المؤلفون: Gresel Martinez, Min Ren, Jean Fan, Robert Shumaker, Jagadeesh Aluri, Helen S. Pentikis

المصدر: The Journal of Clinical Pharmacology. 55:317-327

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, medicine.drug_class, Cmax, Administration, Oral, Urine, Models, Biological, Severity of Illness Index, Gastroenterology, Tyrosine-kinase inhibitor, chemistry.chemical_compound, Pharmacokinetics, Tandem Mass Spectrometry, Oral administration, Internal medicine, Humans, Medicine, Pharmacology (medical), Protein Kinase Inhibitors, Biotransformation, Pharmacology, business.industry, Liver Diseases, Phenylurea Compounds, Hepatic impairment, PK Parameters, Middle Aged, United States, Renal Elimination, Endocrinology, Liver, chemistry, Quinolines, Female, business, Lenvatinib, Chromatography, Liquid, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2d6ccd73cc92ce4f414752493d21faTest
https://doi.org/10.1002/jcph.398Test

المؤلفون: Gary A. Thompson, Robert Shumaker, Gresel Martinez, Jean Fan, Min Ren, Jagadeesh Aluri

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: medicine.medical_specialty, CYP3A4, ketoconazole, Cmax, Pharmaceutical Science, lenvatinib, Pharmacology, chemistry.chemical_compound, Pharmacokinetics, Oral administration, Internal medicine, medicine, Pharmacology (medical), Volume of distribution, business.industry, Articles, Drug interaction, Endocrinology, chemistry, E7080, Ketoconazole, Lenvatinib, business, pharmacokinetics, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006878df072abf67e98b86585d9f776fTest
https://doi.org/10.1002/cpdd.140Test

المؤلفون: Gary A. Thompson, Min Ren, Gresel Martinez, Jean Fan, Robert Shumaker, Jagadeesh Aluri

المصدر: Clinical Drug Investigation

مصطلحات موضوعية: Adult, Male, medicine.drug_class, Antibiotics, Administration, Oral, Pharmacology, Tyrosine-kinase inhibitor, Young Adult, chemistry.chemical_compound, Pharmacotherapy, Pharmacokinetics, Tandem Mass Spectrometry, Cytochrome P-450 CYP3A, medicine, Humans, Drug Interactions, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Original Research Article, Antibiotics, Antitubercular, Protein Kinase Inhibitors, Chromatography, High Pressure Liquid, CYP3A4, business.industry, Phenylurea Compounds, Cytochrome P-450 CYP3A Inducers, General Medicine, Middle Aged, Therapeutic Equivalency, chemistry, Area Under Curve, Quinolines, Female, Rifampin, Lenvatinib, business, Rifampicin, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000d3cb705e818926da5be27028d937cTest
https://doi.org/10.1007/s40261-014-0217-yTest

المؤلفون: Chip Stewart, Mariela Sivina, Yu Long Han, Kristian Cibulskis, Stacey Gabriel, Sergej Konoplev, Julia Hoellenriegel, David A. Weitz, Michael J. Keating, Amaro Taylor-Weiner, Cameron Fraser, Lillian Werner, Martin A. Nowak, Thorsten Zenz, Carrie Sougnez, Gad Getz, Jennifer R. Brown, Youzhong Wan, Donna Neuberg, Kristopher A. Sarosiek, Susan O'Brien, Huidan Zhang, Dan A. Landau, Jean Fan, Lili Wang, Hagop M. Kantarjian, William G. Wierda, Ivana Bozic, Anthony Letai, Jan A. Burger, Scott L. Carter, Peter Kharchencko, Lynne V. Abruzzo, Lihua Zou, Catherine J. Wu, Paola Dal Cin, Adrian M. Dubuc, Matthew S. Davids, Shuqiang Li, Kenneth J. Livak, Eric S. Lander

المساهمون: Massachusetts Institute of Technology. Department of Biology, Lander, Eric Steven

المصدر: Nature communications, vol 7, iss 1
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature

مصطلحات موضوعية: 0301 basic medicine, Male, Lymphoma, Drug Resistance, General Physics and Astronomy, Apoptosis, Drug resistance, medicine.disease_cause, Somatic evolution in cancer, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, hemic and lymphatic diseases, 80 and over, Agammaglobulinaemia Tyrosine Kinase, Chronic, Cancer, Aged, 80 and over, Mutation, Multidisciplinary, Leukemia, biology, Hematology, Middle Aged, Protein-Tyrosine Kinases, Lymphocytic, 3. Good health, Local, 030220 oncology & carcinogenesis, Ibrutinib, Female, Haploinsufficiency, Tyrosine kinase, Adult, Science, and over, General Biochemistry, Genetics and Molecular Biology, Article, Clonal Evolution, 03 medical and health sciences, Rare Diseases, Genetic, Clinical Research, medicine, Genetics, Bruton's tyrosine kinase, Humans, Selection, Genetic, Selection, Aged, Adenine, Human Genome, B-Cell, General Chemistry, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, 030104 developmental biology, Neoplasm Recurrence, Pyrimidines, Good Health and Well Being, chemistry, Drug Resistance, Neoplasm, Immunology, Cell Transdifferentiation, biology.protein, Pyrazoles, Neoplasm, Histiocytic Sarcoma, Neoplasm Recurrence, Local

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a726afcf552a4d4639969d4bedcd3fTest
https://escholarship.org/uc/item/0p25f2hxTest

المؤلفون: Min Ren, Jean Fan, Gresel Martinez, Jagadeesh Aluri, Kun Chen, Robert Shumaker

المصدر: International journal of clinical pharmacology and therapeutics. 52(4)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Chemistry, Pharmaceutical, Cmax, Biological Availability, Bioequivalence, Gastroenterology, chemistry.chemical_compound, Food-Drug Interactions, Pharmacokinetics, Oral administration, Internal medicine, medicine, Humans, Pharmacology (medical), Protein Kinase Inhibitors, Pharmacology, Cross-Over Studies, Phenylurea Compounds, Middle Aged, Crossover study, Healthy Volunteers, Bioavailability, chemistry, Tolerability, Area Under Curve, Quinolines, Lenvatinib

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fa69d51b6271da7ea291141dc5944dTest
https://pubmed.ncbi.nlm.nih.gov/24548978Test

المؤلفون: Jagadeesh Aluri, Gresel Martinez, Gary A. Thompson, Jean Fan, Min Ren, Robert Shumaker

المصدر: Molecular Cancer Therapeutics. 12:A5-A5

مصطلحات موضوعية: Cancer Research, CYP3A4, business.industry, Nausea, Cmax, Bioequivalence, Pharmacology, Confidence interval, chemistry.chemical_compound, Oncology, Pharmacokinetics, chemistry, Medicine, medicine.symptom, business, Lenvatinib, Adverse effect

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a094395f702e7c6bcbea2df8620ebdc2Test
https://doi.org/10.1158/1535-7163.targ-13-a5Test

المؤلفون: Gresel Martinez, Jean Fan, Robert Shumaker, Borje Darpo, Meijian Zhou, Min Ren

المصدر: Molecular Cancer Therapeutics. 10:C116-C116

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, business.industry, Pharmacology, Placebo, QT interval, Crossover study, Confidence interval, QRS complex, chemistry.chemical_compound, Oncology, chemistry, Moxifloxacin, Internal medicine, Heart rate, Cardiology, Medicine, business, Lenvatinib, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::99f6424d81d037bab091d6bd85c1a002Test
https://doi.org/10.1158/1535-7163.targ-11-c116Test

المؤلفون: David Miller, Yasuhiro Funahashi, Agustin A. Garcia, Tadashi Kadowaki, Michael Teneriello, Richard T. Penson, James P. O'Brien, Cristina Ligia Cebotaru, Min Ren, Matthew A. Powell, Ignace Vergote, Mariusz Bidziński, Nicole Meneses, Olga N. Mikheeva, Tamás Pintér, Jean Fan

المصدر: ResearcherID
David Scott Miller
Web of Science

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Pathology, Predictive marker, Angiogenesis, business.industry, Endometrial cancer, Angiopoietin 2, medicine.disease, Recurrent Endometrial Cancer, chemistry.chemical_compound, chemistry, Receptor tyrosine kinase inhibitor, Internal medicine, Medicine, In patient, business, Lenvatinib

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fcc7d913d411d76edff47caf8fddcfTest
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335419602034&KeyUID=WOS:000335419602034Test

المؤلفون: Min Ren, Yasuhiro Funahashi, Nicole Meneses, Pallavi Sachdev, Matthew A. Powell, David Miller, Tadashi Kadowaki, Richard T. Penson, James P. O'Brien, Ignace Vergote, Jean Fan

المصدر: ResearcherID
David Scott Miller

مصطلحات موضوعية: Cancer Research, business.industry, Endometrial cancer, Phases of clinical research, medicine.disease, chemistry.chemical_compound, Oncology, chemistry, Receptor tyrosine kinase inhibitor, Cancer research, medicine, Biomarker (medicine), In patient, Lenvatinib, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e49f077de7f6924f128b6fc0a3ab7a4Test
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335419602104&KeyUID=WOS:000335419602104Test