نتائج البحث - "Georg Auburger"

1

Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis

المؤلفون: Sylvia Torres-Odio, A. Phillip West, Suzana Gispert, Jana Key, Yuanjiu Lei, Saeed S. Menissy, Georg Auburger, Ilka Wittig, Antonia Maletzko

المصدر: J Immunol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e083fd84950a7e2bbe3b0fe22a446bbbTest
https://pubmed.ncbi.nlm.nih.gov/33820828Test

2

In Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism

المؤلفون: Nesli-Ece Sen, Susanne Brodesser, Konrad Sandhoff, Melanie Vanessa Halbach, Júlia Canet-Pons, Carola Oberschmidt, Zeynep-Ece Kaya, Aleksandar Arsovic, David Meierhofer, Suzana Gispert, Georg Auburger

مصطلحات موضوعية: Ceramide, chemistry.chemical_compound, chemistry, Ataxin, Leukodystrophy, medicine, lipids (amino acids, peptides, and proteins), endocrinology_metabolomics, Sphingomyelin metabolism, Tauopathy, Biology, medicine.disease, Cell biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ea74764a16e7980f2fbdcd6bb505f7Test

3

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism

المؤلفون: Georg Auburger, Susanne Brodesser, Zeynep-Ece Kaya, Júlia Canet-Pons, Aleksandar Arsovic, Carola Oberschmidt, Nesli-Ece Sen, Suzana Gispert, Konrad Sandhoff, Melanie-Vanessa Halbach, David Meierhofer

المساهمون: İÜC, Cerrahpaşa Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü

المصدر: International Journal of Molecular Sciences, Vol 20, Iss 23, p 5854 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 23

مصطلحات موضوعية: acid sphingomyelinase (ASMase, leukodystrophy, amyotrophic lateral sclerosis (ALS), neutral sphingomyelinase (Smpd3), neutral ceramidase (asah2), serine palmitoyltransferase 2 (sptlc2), smpd1), lcsh:Chemistry, Myelin, chemistry.chemical_compound, fatty acid elongase (Elovl1/4/5), Sphingosine N-Acyltransferase, lcsh:QH301-705.5, Spectroscopy, Ataxin-2, Mice, Knockout, General Medicine, Computer Science Applications, Cell biology, Sphingomyelins, SCA38, medicine.anatomical_structure, Sphingomyelin Phosphodiesterase, amyotrophic lateral sclerosis (als), acid sphingomyelinase (asmase, SCA34, Knockout mouse, Spinocerebellar ataxia, sca34, lipids (amino acids, peptides, and proteins), Sphingomyelin, sca38, Ceramide, olivo-ponto-cerebellar atrophy (opca), Biology, Ceramides, Catalysis, Article, Inorganic Chemistry, ddc:570, medicine, Animals, Humans, Spinocerebellar Ataxias, serine palmitoyltransferase 2 (Sptlc2), ddc:610, Physical and Theoretical Chemistry, Eye Proteins, Molecular Biology, Smpd1), Sphingosine, fatty acid elongase (elovl1/4/5), Nervous tissue, Organic Chemistry, Membrane Proteins, olivo-ponto-cerebellar atrophy (OPCA), medicine.disease, Lipid Metabolism, ceramide synthase (cers2/cers1), Disease Models, Animal, chemistry, lcsh:Biology (General), lcsh:QD1-999, Ataxin, neutral sphingomyelinase (smpd3), neutral ceramidase (Asah2), ceramide synthase (CERS2/CERS1), Trinucleotide Repeat Expansion

وصف الملف: application/pdf; application/zip; application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d375b355a0af0e0d43d23b91b974bbe0Test
https://www.mdpi.com/1422-0067/20/23/5854Test

4

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation

المؤلفون: Suzana Gispert, Blas Morales-Gordo, Georg Auburger, Lucie Valek, Bastian Roller, David Meierhofer, Júlia Canet-Pons, Jana Key, Irmgard Tegeder, Patrick N. Harter, Hans-Hermann Hoepken, Michel Mittelbronn, Michael Walter, Sylvia Torres-Odio

المصدر: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-26 (2017)

مصطلحات موضوعية: 0301 basic medicine, Pathology, Aging, Parkinson's disease, Parkin, lcsh:RC346-429, chemistry.chemical_compound, Mice, Neuroblastoma, Ubiquitin, Neuroinflammation, Mitophagy, Cells, Cultured, Cerebral Cortex, Neurons, biology, General Neuroscience, Microfilament Proteins, Age Factors, Parkinson Disease, Endoplasmic Reticulum Stress, Ubiquitin ligase, medicine.anatomical_structure, Neurology, Antiviral response, Disease Progression, alpha-Synuclein, medicine.medical_specialty, RNA Splicing, Immunology, Mice, Transgenic, 03 medical and health sciences, Cellular and Molecular Neuroscience, medicine, Animals, Humans, ddc:610, lcsh:Neurology. Diseases of the nervous system, Alpha-synuclein, Research, Gene Expression Profiling, Calcium-Binding Proteins, Ubiquitination, Lipid Metabolism, Disease Models, Animal, 030104 developmental biology, chemistry, biology.protein, Unfolded protein response, Parkinson’s disease, Neuron, Mitochondrial dysfunction, Protein Kinases, Ubiquitin kinase PINK1

وصف الملف: application/pdf; application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af4076a588b6aedcfb22b791953189bTest
https://hdl.handle.net/10668/11465Test

5

A Genetic Mouse Model of Parkinson’s Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine

المؤلفون: Nadine Brehm, Georg Auburger, T. Carlsson, Beatrice Kern, Francesco Bez, Suzana Gispert, M. A. Cenci

المصدر: Molecular Neurobiology. 52:1152-1164

مصطلحات موضوعية: Genetically modified mouse, medicine.medical_specialty, Parkinson's disease, Apomorphine, MAP Kinase Signaling System, Prions, Mutation, Missense, Neuroscience (miscellaneous), Nigrostriatal pathway, Mice, Transgenic, Nerve Tissue Proteins, Neurotransmission, Biology, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Parkinsonian Disorders, Postsynaptic potential, Dopamine, Internal medicine, medicine, Animals, Humans, Point Mutation, Transgenes, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Promoter Regions, Genetic, Alpha-synuclein, Dyskinesias, Dopaminergic Neurons, Post-Synaptic Density, medicine.disease, Corpus Striatum, Substantia Nigra, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, Neurology, chemistry, alpha-Synuclein, Stereotyped Behavior, Protein Processing, Post-Translational, Locomotion, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c092a3825e5bae727b88670176259f6fTest
https://doi.org/10.1007/s12035-014-8911-6Test

6

Blood RNA biomarkers in prodromal PARK4 and REM sleep behavior disorder show role of complexin-1 lass for risk of Parkinson's diseaseA

المصدر: Disease models and mechanisms

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d6d359d653032050e1f0418e829e79Test
https://hdl.handle.net/11858/00-001M-0000-002D-7056-611858/00-001M-0000-002D-7054-ATest

7

Mechanisms underlying altered striatal synaptic plasticity in old A53T-α synuclein overexpressing mice

المؤلفون: Barbara Picconi, Cinzia Costa, Paolo Calabresi, Alexander Kurz, Georg Auburger, Michela Tantucci, Suzana Gispert, Sabrina Siliquini, Alessandro Tozzi

المصدر: Neurobiology of Aging

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7529789ab9dec611f36d4742765db817Test
https://doi.org/10.1016/j.neurobiolaging.2011.05.002Test

8

Striatal dopamine transmission is subtly modified in human A53T(Alpha)-synuclein overexpressing mice

المؤلفون: Suzana Gispert, Nicola J. Platt, Georg Auburger, Stephanie J. Cragg

المصدر: PLoS ONE, Vol 7, Iss 5, p e36397 (2012)
PLoS ONE

مصطلحات موضوعية: medicine.medical_specialty, Transgene, Dopamine, Science, Neurophysiology, Gene Expression, Mice, Transgenic, Striatum, Nucleus accumbens, Biology, Neurotransmission, Synaptic Transmission, chemistry.chemical_compound, Mice, Neuropharmacology, Internal medicine, Gene expression, Neurobiology of Disease and Regeneration, medicine, Animals, Humans, ddc:610, Alpha-synuclein, Multidisciplinary, Neuromodulation, Neurochemistry, Parkinson Disease, Neurotransmitters, Acetylcholine, Corpus Striatum, Endocrinology, chemistry, Neurology, Amino Acid Substitution, nervous system, Synapses, Mutation, Synuclein, alpha-Synuclein, Medicine, Female, Neurochemicals, medicine.drug, Research Article, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac70f45f8d2a32077b1ae0b7c8bd04aTest
https://ora.ox.ac.uk/objects/uuid:dec293c5-8465-4479-8717-ff75bbfdf572Test

9

Age-Related Changes of 14-3-3 Isoforms in Midbrain of A53T-SNCA Overexpressing Mice

المؤلفون: Katrin Rau, Suzana Gispert, Nadine Brehm, Alexander Kurz, Georg Auburger

المصدر: Journal of Parkinson's disease. 5(3)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5f552d61a0692c2d8048f6747df916Test
https://pubmed.ncbi.nlm.nih.gov/26406140Test

10

The role of glyoxalases for sugar stress and aging, with relevance for dyskinesia, anxiety, dementia and Parkinson's disease

المؤلفون: Georg Auburger, Alexander Kurz

المصدر: Aging. 3:5-9

مصطلحات موضوعية: Aging, biology, Methylglyoxal, Cell Biology, Glutathione, Hydroxyacylglutathione hydrolase, chemistry.chemical_compound, Lactoylglutathione lyase, chemistry, Biochemistry, Anaerobic glycolysis, ddc:570, biology.protein, Glycolysis, NAD+ kinase, Dihydroxyacetone phosphate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15681c46d34067800c4a8729779d01bTest
https://doi.org/10.18632/aging.100258Test

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