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المؤلفون: Ross Chawner, Sonia Mazzitelli, Ross Jeggo, Claire E. Eyers, David Spanswick, Jasmeet Virdee, J. Mark Treherne, Alun Williams, David I.C. Scopes, Hozefa Amijee, Clive Bate, Andrew J. Doig
المصدر: Biochemistry. 51:8338-8352
مصطلحات موضوعية: Male, Programmed cell death, Circular dichroism, Cell Survival, Long-Term Potentiation, Peptide, Biochemistry, Oligomer, Mice, chemistry.chemical_compound, Alzheimer Disease, Lactate dehydrogenase, Tumor Cells, Cultured, Animals, Humans, Benzothiazoles, Protein Structure, Quaternary, Neurons, chemistry.chemical_classification, Amyloid beta-Peptides, Circular Dichroism, Long-term potentiation, Surface Plasmon Resonance, Peptide Fragments, Rats, Thiazoles, chemistry, Toxicity, Thioflavin, Protein Multimerization, Oligopeptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222e325f86e334145f0d7f75c2c725e9Test
https://doi.org/10.1021/bi300415vTest -
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المؤلفون: Victoria Ingham, Alun Williams, Clive Bate
المصدر: Neuropharmacology. 60:365-372
مصطلحات موضوعية: Gene isoform, Phospholipase A2 Inhibitors, Prions, Organophosphonates, Peptide, Arachidonic Acids, Biology, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Phospholipase A2, Animals, Humans, Receptor, Lipid raft, Cells, Cultured, Cerebral Cortex, Neurons, Pharmacology, chemistry.chemical_classification, Phospholipase A, Platelet-activating factor, Cholesterol, Peptide Fragments, Cell biology, Phospholipases A2, Protein Transport, chemistry, Biochemistry, biology.protein, lipids (amino acids, peptides, and proteins)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727fa08e89f717e9c89224629290d756Test
https://doi.org/10.1016/j.neuropharm.2010.10.001Test -
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المؤلفون: Clive Bate, Scott Rutherford, Alun Williams, Mike B. Gravenor, Stuart Reid
المصدر: NeuroReport. 13:1933-1938
مصطلحات موضوعية: PrPSc Proteins, Cell Survival, Prions, animal diseases, Glutamic Acid, Prostaglandin, Biology, Dinoprostone, Prion Diseases, Mice, Neuroblastoma, chemistry.chemical_compound, Fetus, Tumor Cells, Cultured, medicine, Animals, Neurotoxin, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Cerebral Cortex, Neurons, chemistry.chemical_classification, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Microglia, General Neuroscience, Anti-Inflammatory Agents, Non-Steroidal, Neurotoxicity, Membrane Proteins, medicine.disease, Peptide Fragments, In vitro, nervous system diseases, Isoenzymes, Mice, Inbred C57BL, Neuroprotective Agents, medicine.anatomical_structure, Enzyme, Animals, Newborn, chemistry, Eicosanoid, Biochemistry, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Cyclooxygenase 1, Arachidonic acid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6aaf2fc0ce08de17c784ae58693083Test
https://doi.org/10.1097/00001756-200210280-00021Test -
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المؤلفون: Clive Bate, Sarah L. Kempster, Alun Williams
المصدر: Neuropharmacology. 51(2)
مصطلحات موضوعية: CD14, Recombinant Fusion Proteins, Receptors, Prostaglandin, Lipopolysaccharide Receptors, Biology, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, medicine, Animals, Platelet Activating Factor, Receptors, Immunologic, Receptor, Cells, Cultured, Pharmacology, Cerebral Cortex, Mice, Knockout, Neurons, Amyloid beta-Peptides, Microglia, Platelet-activating factor, Cell Death, Antagonist, Neurotoxicity, Prostanoid, respiratory system, medicine.disease, Coculture Techniques, Peptide Fragments, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, Neuroprotective Agents, nervous system, Biochemistry, chemistry, Immunoglobulin G, Second messenger system, lipids (amino acids, peptides, and proteins), Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1352f59c28db0ca0bc44ffd9791d120Test
https://pubmed.ncbi.nlm.nih.gov/16678220Test -
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المؤلفون: Alun Williams, Clive Bate, Mario Salmona
المصدر: Neuroreport. 15(3)
مصطلحات موضوعية: Amyloid beta, Prions, animal diseases, Pharmacology, Dinoprostone, Phospholipases A, chemistry.chemical_compound, Neuroblastoma, Phospholipase A2, medicine, Tumor Cells, Cultured, Humans, Prostaglandin E2, Platelet Activating Factor, Phospholipase A, Amyloid beta-Peptides, biology, Platelet-activating factor, Cell Death, Brain Neoplasms, Caspase 3, General Neuroscience, Neurodegeneration, Neurotoxicity, medicine.disease, Peptide Fragments, nervous system diseases, Phospholipases A2, Biochemistry, chemistry, Caspases, biology.protein, Alzheimer's disease, Nervous System Diseases, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b9872898e204e9f74c85f3eb564efbTest
https://pubmed.ncbi.nlm.nih.gov/15094513Test -
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المؤلفون: Jan P. M. Langeveld, Rob H. Meloen, Ronald S. Boshuizen, Johannes P. M. Langedijk, Mario Salmona, Alun Williams
المصدر: Analytical Biochemistry, 333(2), 372-380
Analytical Biochemistry 333 (2004) 2مصطلحات موضوعية: Models, Molecular, Time Factors, Amyloid, Prions, Molecular Sequence Data, Biophysics, Drug Evaluation, Preclinical, Scrapie, Peptide, Biology, cultured-cells, Fibril, Biochemistry, Sensitivity and Specificity, chemistry.chemical_compound, dextran sulfate, Humans, Amino Acid Sequence, Benzothiazoles, alzheimers-disease, congo red, CIDC - Divisie Bacteriologie en TSE's, Molecular Biology, Peptide sequence, Fluorescent Dyes, chemistry.chemical_classification, prp, Staining and Labeling, molecular-cloning, scrapie, Reproducibility of Results, Neurodegenerative Diseases, Cell Biology, Tetracycline, thioflavine-t, In vitro, Peptide Fragments, Congo red, nervous system diseases, Transmembrane domain, Thiazoles, branched polyamines, chemistry, stained amyloid fibrils, Neurofibrils, Gelatin
وصف الملف: application/octet-stream; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f24566fc784506917975ab0dd3679e6Test
https://research.wur.nl/en/publications/an-in-vitro-screening-assay-based-on-synthetic-prion-protein-peptTest -
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المؤلفون: Alun Williams, Robert Veerhuis, Clive Bate, Piet Eikelenboom
المساهمون: Neurology
المصدر: Neuroreport, 14(16), 2099-2103. Lippincott Williams and Wilkins
مصطلحات موضوعية: medicine.medical_specialty, Lipoxygenase, Drug Resistance, Prostaglandin, Biology, Pharmacology, Dinoprostone, Mice, chemistry.chemical_compound, Fetus, Alzheimer Disease, Cell Line, Tumor, Internal medicine, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Animals, Humans, Cyclooxygenase Inhibitors, Prostaglandin E2, Cerebral Cortex, Neurons, chemistry.chemical_classification, Amyloid beta-Peptides, Cyclooxygenase 2 Inhibitors, General Neuroscience, Anti-Inflammatory Agents, Non-Steroidal, Neurotoxicity, Membrane Proteins, medicine.disease, Peptide Fragments, Isoenzymes, Neuroprotective Agents, Enzyme, Endocrinology, Eicosanoid, chemistry, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Enzyme inhibitor, Cyclooxygenase 1, biology.protein, Arachidonic acid, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4f054fca167bfe8335dc297b1f7ed5Test
https://pure.amc.nl/en/publications/neurones-treated-with-cyclooxygenase1-inhibitors-are-resistant-to-amyloidbeta142Test(315eacca-b5e0-46cd-8284-ed3759e1d315).html