المؤلفون: Philip S. Tsao, Themistocles L. Assimes, Katherine M. Siewert, Derek Klarin, Kelsey E. Johnson, Benjamin F. Voight, Kara N. Maxwell, Scott M. Damrauer, Kyong-Mi Chang

المصدر: PLoS Medicine
PLoS Medicine, Vol 17, Iss 9, p e1003302 (2020)

مصطلحات موضوعية: Male, Oncology, Epidemiology, 030204 cardiovascular system & hematology, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Breast Tumors, Odds Ratio, Medicine and Health Sciences, Macromolecular Structure Analysis, Medicine, 030212 general & internal medicine, Lipid Analysis, biology, Cancer Risk Factors, Confounding, General Medicine, Middle Aged, Lipids, Phenotype, Cholesterol, Female, lipids (amino acids, peptides, and proteins), Research Article, Adult, medicine.medical_specialty, Lipoproteins, Breast Neoplasms, Population stratification, Polymorphism, Single Nucleotide, 03 medical and health sciences, Internal medicine, Cholesterylester transfer protein, Mendelian randomization, Breast Cancer, Genetics, Humans, Genetic Predisposition to Disease, Molecular Biology, Triglycerides, Genetic association, business.industry, Cholesterol, HDL, Biology and Life Sciences, Proteins, Cancers and Neoplasms, Cholesterol, LDL, Odds ratio, Mendelian Randomization Analysis, chemistry, Genetic Loci, Medical Risk Factors, biology.protein, business, Genome-Wide Association Study, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cf0bae34e36673ee5a45a992c65eb9Test
http://europepmc.org/articles/PMC7485834Test

المؤلفون: Cheryl Nickerson-Nutter, Ehab A. Ayaub, Yen-Hsing Li, Estela Puchulu-Campanella, Madduri Srinivasarao, Philip S. Low, Spencer D. Lindeman, Fenghua Zhang, Konstantin Tsoyi, Bingbing Wang, Suraj U. Hettiarachchi, Sasmita Rout, Abigail Cox, Ivan O. Rosas, Qian Luo

المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), medicine.medical_treatment, Pulmonary Fibrosis, Respiratory System, QH426-470, Bleomycin, Article, Extracellular matrix, 03 medical and health sciences, chemistry.chemical_compound, Idiopathic pulmonary fibrosis, Mice, 0302 clinical medicine, R5-920, Fibrosis, Pulmonary fibrosis, Macrophages, Alveolar, Chemical Biology, medicine, Genetics, Animals, toll‐like receptor 7, folate receptor β, bleomycin, business.industry, Macrophages, virus diseases, TLR7, Articles, Fibroblasts, medicine.disease, idiopathic pulmonary fibrosis, Mice, Inbred C57BL, 030104 developmental biology, Cytokine, chemistry, Toxicity, Cancer research, Molecular Medicine, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8ec9037972638af948a59b037c0d8cTest
https://pubmed.ncbi.nlm.nih.gov/32597014Test

المؤلفون: Tuomo Kiiskinen, Matthew J. Bown, Sekar Kathiresan, James G. Wilson, John Danesh, Heribert Schunkert, Krishna G. Aragam, Joshua C. Denny, Million Veteran Program, Diego Ardissino, Danish Saleheen, Marina Serper, Julie A. Lynch, Marijana Vujkovic, Usman Baber, Alexander G. Bick, George Hindy, Amit Khera, Nilesh J. Samani, Connor A. Emdin, Mark J. Daly, Hugh Watkins, Ruth McPherson, Aki S. Havulinna, QiPing Feng, Scott M. Damrauer, Namrata Gupta, Derek Klarin, Roberto Elosua, Juha Karjalainen, Philip S Tsao, B F Voight, Josep M. Mercader, Craig L. Hanis, Kyong-Mi Chang, Mark Chaffin, Wei-Qi Wei, David E. Kaplan, Stacey Gabriel, Lan Jiang, Jeanette Erdmann, Mary E. Haas

المساهمون: Institute for Molecular Medicine Finland, University of Helsinki, Complex Disease Genetics, Genomics of Neurological and Neuropsychiatric Disorders, HUS Helsinki and Uusimaa Hospital District, Emdin, Connor A. [0000-0003-2337-1229], Haas, Mary E. [0000-0002-2816-9268], Khera, Amit V. [0000-0001-6535-5839], Chaffin, Mark [0000-0002-1234-5562], Klarin, Derek [0000-0002-4636-5780], Jiang, Lan [0000-0002-2583-3661], Wei, Wei-Qi [0000-0003-4985-056X], Feng, Qiping [0000-0002-6213-793X], Havulinna, Aki [0000-0002-4787-8959], Kiiskinen, Tuomo [0000-0002-6306-8227], Bick, Alexander [0000-0001-5824-9595], Ardissino, Diego [0000-0003-0410-3528], Schunkert, Heribert [0000-0001-6428-3001], McPherson, Ruth [0000-0002-9087-6107], Erdmann, Jeanette [0000-0002-4486-6231], Chang, Kyong-Mi [0000-0001-6811-9364], Vujkovic, Marijana [0000-0003-4924-5714], Voight, Ben [0000-0002-6205-9994], Damrauer, Scott [0000-0001-8009-1632], Lynch, Julie [0000-0003-0108-2127], Kaplan, David [0000-0002-3839-336X], Serper, Marina [0000-0003-4899-2160], Tsao, Philip [0000-0001-7274-9318], Mercader, Josep [0000-0001-8494-3660], Hanis, Craig [0000-0002-4880-5348], Denny, Joshua [0000-0002-3049-7332], Apollo - University of Cambridge Repository, Emdin, Connor A [0000-0003-2337-1229], Haas, Mary E [0000-0002-2816-9268], Khera, Amit V [0000-0001-6535-5839]

المصدر: PLoS Genetics, Vol 16, Iss 4, p e1008629 (2020)
PLoS Genetics, Vol 17, Iss 4, p e1009503 (2021)
PLoS Genetics

مصطلحات موضوعية: Liver Cirrhosis, Male, Cancer Research, Cirrhosis, Datasets as Topic, PROTEIN, Coronary Artery Disease, QH426-470, Fetge -- Malalties, Biochemistry, Vascular Medicine, Liver disease, chemistry.chemical_compound, 0302 clinical medicine, Sociology, ANGPTL3, Consortia, Liver Cirrhosis, Alcoholic, Loss of Function Mutation, Psychology, Coronary Heart Disease, CONFERS SUSCEPTIBILITY, Genetics (clinical), 0303 health sciences, Liver Diseases, Homozygote, Fatty liver, 1184 Genetics, developmental biology, physiology, Middle Aged, Lipids, Addicts, 3. Good health, Cholesterol, Liver, Alkaline phosphatase, Female, Oxidoreductases, ENZYMES, Colesterol, Research Article, medicine.medical_specialty, Cirrosi hepàtica, Cardiology, Mutation, Missense, Addiction, Gastroenterology and Hepatology, Biology, Social sciences, TM6SF2, Mitochondrial Proteins, 03 medical and health sciences, Internal medicine, Genetics, medicine, Humans, Genetic Predisposition to Disease, Alcoholics, GENOME-WIDE ASSOCIATION, Molecular Biology, Alleles, Ecology, Evolution, Behavior and Systematics, PNPLA3, 030304 developmental biology, Medicine and health sciences, Biology and life sciences, MORTALITY, Correction, Cholesterol, LDL, medicine.disease, RISK LOCI, Mitochondrial amidoxime reducing component 1, Fatty Liver, Endocrinology, YIELD, chemistry, Alanine transaminase, Genetic Loci, biology.protein, 3111 Biomedicine, Proteïnes, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/zip; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2aeafb245632b250e5e05c8a2d99cdTest
http://hdl.handle.net/10230/47380Test

المؤلفون: Philip S. Stinard, Qin Bao Li, Kwanghee Lee, Jonathan W. Saunders, Maria Magallanes-Lundback, Charles T. Hunter, Denis S. Willett, Karen E. Koch, Dean DellaPenna, Shawn A. Christensen

المصدر: The Plant Journal. 93:799-813

مصطلحات موضوعية: 2. Zero hunger, 0106 biological sciences, 0301 basic medicine, chemistry.chemical_classification, Phytoene desaturase, Mutant, food and beverages, Cell Biology, Plant Science, Biology, 01 natural sciences, Endosperm, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Phytoene, chemistry, Biochemistry, Genetics, Tocopherol, Carotenoid, Abscisic acid, 010606 plant biology & botany, Homogentisate 1,2-dioxygenase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e52693ab57aef3bb8f388a97c68e2adbTest
https://doi.org/10.1111/tpj.13821Test

المؤلفون: Asif Rasheed, Mary F. Feitosa, Ian J. Deary, Melissa E. Garcia, Danish Saleheen, Christian Gieger, Andrea Maschio, Lia E. Bang, Cliona Molony, Ivan Brandslund, Dan M. Roden, Ian Ford, Paul M. Ridker, Alisa K. Manning, Giorgio Pistis, Anette Varbo, Alexander P. Reiner, Kathleen Stirrups, David C. Liewald, Tim D. Spector, Paul W. Franks, Cristen J. Willer, Daniel I. Chasman, Jean Ferrières, Vilmundur Gudnason, Tapani Ebeling, Neil Poulter, Magdalena Zoledziewska, Elizabeth K. Speliotes, Eleftheria Zeggini, Megan L. Grove, Hua Tang, Stavroula Kanoni, Peter Weeke, Panos Deloukas, Daniel J. Rader, Amit Khera, Serena Sanna, Dorota Pasko, Gina M. Peloso, Charles Kooperberg, Suthesh Sivapalaratnam, Natalie R. van Zuydam, Christian M. Shaffer, Fredrik Karpe, Naveed Sattar, Pieter Muntendam, Ruth J. F. Loos, Eric Boerwinkle, Wei Gao, Mark J. Caulfield, Matt Neville, Sangeetha Somayajula, Olle Melander, Hayato Tada, Jose M. Ordovas, He Zhang, John D. Rioux, Michael Boehnke, Erwin P. Bottinger, Franco Giulianini, Martina Müller-Nurasyid, Stella Trompet, Connor A. Emdin, Andrew P. Morris, Johanne Marie Justesen, Alan R. Tall, Kari Kuulasmaa, Adam S. Butterworth, Marie-Pierre Dubé, Dajiang J. Liu, Paul L. Auer, Jennifer E. Huffman, Usman Baber, John Danesh, Xiao Wang, Anna F. Dominiczak, Jarmo Virtamo, John M. Starr, Ozren Polasek, Gonçalo R. Abecasis, Timo A. Lakka, Stephen S. Rich, Marco M Ferrario, Marju Orho-Melander, Xueling Sim, Dominique Arveiler, Dermot F. Reilly, Torsten Lauritzen, Gudny Eiriksdottir, Marit E. Jørgensen, Anubha Mahajan, Colin N. A. Palmer, Veikko Salomaa, Nicholas J. Wareham, Dewan S. Alam, Anne Tybjærg-Hansen, Ellen M. Schmidt, Y. Eugene Chen, Heather M. Stringham, Bruce M. Psaty, Christie M. Ballantyne, Nan Wang, Joshua C. Bis, Myriam Fornage, Neil S Zheng, Kristian Hveem, Praveen Surendran, Yingchang Lu, Peter S. Sever, James B. Meigs, Heikki A. Koistinen, Charlotta Pisinger, Tibor V. Varga, Yii-Der Ida Chen, Konstantin Strauch, Timothy M. Frayling, Patricia B. Munroe, Albert V. Smith, Ruth Frikke-Schmidt, Lorraine Southam, Frida Renström, Philippe Amouyel, Nicholas G. D. Masca, Alexessander Couto Alves, Xiangfeng Lu, Andres Metspalu, Anne Langsted, Joanna M. M. Howson, Tamara B. Harris, Leif Groop, Chad A. Cowan, Cramer Christensen, Audrey Y. Chu, Markku Laakso, Torben Hansen, Li-An Lin, John C. Chambers, Jonas B. Nielsen, Niels Grarup, Neil R. Robertson, Kiran Musunuru, Joshua S. Weinstock, Morris J. Brown, Jean-Claude Tardif, Gorm B. Jensen, Jerome I. Rotter, Harald Grallert, Yan Zhang, Kerrin S. Small, Nathan O. Stitziel, Fabio Busonero, Jennifer Wessel, Themistocles L. Assimes, Lenore J. Launer, Lars G. Fritsche, Mark O. Goodarzi, Peter W.F. Wilson, Sekar Kathiresan, Philippe M. Frossard, Emanuele Di Angelantonio, Yanhua Zhou, James G. Wilson, Frank Kee, Scott M. Damrauer, Weihua Zhang, Gail Davies, Oluf Pedersen, Sune F. Nielsen, Alanna C. Morrison, Raquel S. Sevilla, Helen R. Warren, Johanna Kuusisto, Hanieh Yaghootkar, Sandosh Padmanabhan, Philip S. Tsao, Caroline Hayward, Tõnu Esko, Ming Xu, Anders Mälarstig, Anne U. Jackson, Eirini Marouli, Jette Bork-Jensen, Robin Young, C.J. O'Donnell, Yong Huo, Melanie Waldenberger, Jaspal S. Kooner, Pekka Mäntyselkä, Marjo-Riitta Järvelin, Santhi K. Ganesh, Annette Peters, L. Adrienne Cupples, Wei Zhou, Derek Klarin, Markus Perola, Francesco Cucca, Allan Linneberg, Mark I. McCarthy, Joel N. Hirschhorn, Pia R. Kamstrup, Nilesh J. Samani, J. Wouter Jukema, Valentin Fuster, Claudia Langenberg, Roxana Mehran, Børge G. Nordestgaard, Jaakko Tuomilehto, Reedik Mägi, Blair H. Smith, Johanna Jakobsdottir, Marianne Benn, Kent D. Taylor, Ani Manichaikul, Igor Rudan, Aniruddh P. Patel, Joshua C. Denny, Oddgeir L. Holmen, John M. C. Connell, Robert A. Scott, Haojie Yu, Rajiv Chowdhury, Sehrish Jabeen, Antonella Mulas, Aliki-Eleni Farmaki, Rainer Rauramaa, George Dedoussis

المساهمون: Vascular Medicine, Nielsen, Jonas B [0000-0002-6654-2852], Kathiresan, Sekar [0000-0002-6724-032X], Apollo - University of Cambridge Repository, Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI)

المصدر: Nature genetics, 49(12), 1758-1766. Nature Publishing Group
NATURE GENETICS
Liu, D J, Peloso, G M, Yu, H, Butterworth, A S, Wang, X, Mahajan, A, Saleheen, D, Emdin, C, Alam, D, Alves, A C, Amouyel, P, Di Angelantonio, E, Arveiler, D, Assimes, T L, Auer, P L, Baber, U, Ballantyne, C M, Bang, L E, Benn, M, Bis, J C, Boehnke, M, Boerwinkle, E, Bork-Jensen, J, Bottinger, E P, Brandslund, I, Brown, M, Busonero, F, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y E, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Connell, J M, Cucca, F, Cupples, L A, Damrauer, S M, Davies, G, Deary, I J, Dedoussis, G, Denny, J C, Dominiczak, A, Dubé, M-P, Ebeling, T, Eiriksdottir, G, Hansen, T, Jensen, G B, Jørgensen, M E & Charge Diabetes Working Group 2017, ' Exome-wide association study of plasma lipids in >300,000 individuals ', Nature Genetics, vol. 49, no. 12, pp. 1758–1766 . https://doi.org/10.1038/ng.3977Test
Nature Genetics
Liu, D J, Peloso, G M, Yu, H, Butterworth, A S, Wang, X, Mahajan, A, Saleheen, D, Emdin, C, Alam, D, Alves, A C, Amouyel, P, Angelantonio, E DI, Arveiler, D, Assimes, T L, Auer, P L, Baber, U, Ballantyne, C M, Bang, L E, Benn, M, Bis, J C, Boehnke, M, Boerwinkle, E, Bork-Jensen, J, Bottinger, E P, Brandslund, I, Brown, M, Busonero, F, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y E, Chen, Y D I, Chowdhury, R, Christensen, C, Chu, A Y, Connell, J M, Cucca, F, Cupples, L A, Damrauer, S M, Davies, G, Deary, I J, Dedoussis, G, Denny, J C, Dominiczak, A, Dubé, M P, Ebeling, T, Eiriksdottir, G, Esko, T, Farmaki, A E, Feitosa, M F, Ferrario, M, Ferrieres, J, Ford, I, Fornage, M, Franks, P W, Frayling, T M, Frikke-Schmidt, R, Fritsche, L G, Frossard, P, Fuster, V, Ganesh, S K, Gao, W, Garcia, M E, Gieger, C, Giulianini, F, Goodarzi, M O, Grallert, H, Grarup, N, Groop, L, Grove, M L, Gudnason, V, Hansen, T, Harris, T B, Hayward, C, Hirschhorn, J N, Holmen, O L, Huffman, J, Huo, Y, Hveem, K, Jabeen, S, Jackson, A U, Jakobsdottir, J, Jarvelin, M R, Jensen, G B, Jørgensen, M E, Jukema, J W, Justesen, J M, Kamstrup, P R, Kanoni, S, Karpe, F, Kee, F, Khera, A V, Klarin, D, Koistinen, H A, Kooner, J S, Kooperberg, C, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T, Langenberg, C, Langsted, A, Launer, L J, Lauritzen, T, MLiewald, D C, Lin, L A, Linneberg, A, Loos, R J F, Lu, Y, Lu, X, Mägi, R, Malarstig, A, Manichaikul, A, Manning, A K, Mäntyselkä, P, Marouli, E, Masca, N G D, Maschio, A, Meigs, J B, Melander, O, Metspalu, A, Morris, A P, Morrison, A C, Mulas, A, Müller-Nurasyid, M, Munroe, P B, Neville, M J, Nielsen, S F, Nielsen, J B, Nordestgaard, B G, Ordovas, J M, Mehran, R, O'Donnell, C J, Orho-Melander, M, Molony, C M, Muntendam, P, Padmanabhan, S, Palmer, C N A, Pasko, D, Patel, A P, Pedersen, O, Perola, M, Peters, A, Pisinger, C, Pistis, G, Polasek, O, Poulter, N, Psaty, B M, Rader, D J, Rasheed, A, Rauramaa, R, Reilly, D F, Reiner, A P, Renström, F, Rich, S S, Ridker, P M, Rioux, J D, Robertson, N R, Roden, D M, Rotter, J I, Rudan, I, Salomaa, V, Samani, N J, Sanna, S, Sattar, N, Schmidt, E M, Scott, R A, Sever, P, Sevilla, R S, Shaffer, C M, Sim, X, Sivapalaratnam, S, Small, K S, Smith, A V, Smith, B H, Somayajula, S, Southam, L, Spector, T D, Speliotes, E K, Starr, J M, Stirrups, K E, Stitziel, N, Strauch, K, Stringham, H M, Surendran, P, Tada, H, Tall, A R, Tang, H, Tardif, J C, Taylor, K D, Trompet, S, Tsao, P S, Tuomilehto, J, Tybjaerg-Hansen, A, Zuydam, N R V, Varbo, A, Varga, T V, Virtamo, J, Waldenberger, M, Wang, N, Wareham, N J, Warren, H R, Weeke, P E, Weinstock, J, Wessel, J, Wilson, J G, Wilson, P W F, Xu, M, Yaghootkar, H, Young, R, Zeggini, E, Zhang, H, Zheng, N S, Zhang, W, Zhang, Y, Zhou, W, Zhou, Y, Zoledziewska, M, Howson, J M M, Danesh, J, McCarthy, M I, Cowan, C A, Abecasis, G, Deloukas, P, Musunuru, K, Willer, C J, Kathiresan, S & V Varga, T 2017, ' Exome-wide association study of plasma lipids in >300,000 individuals ', Nature Genetics, vol. 49, no. 12, pp. 1758-1766 . https://doi.org/10.1038/ng.3977Test
Liu, D J, Peloso, G M, Yu, H, Butterworth, A S, Wang, X, Mahajan, A, Saleheen, D, Emdin, C, Alam, D, Alves, A C, Amouyel, P, Di Angelantonio, E, Arveiler, D, Assimes, T L, Auer, P L, Baber, U, Ballantyne, C M, Bang, L E, Benn, M, Bis, J C, Boehnke, M, Boerwinkle, E, Bork-jensen, J, Bottinger, E P, Brandslund, I, Brown, M, Busonero, F, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y E, Chen, Y I, Chowdhury, R, Christensen, C, Chu, A Y, Connell, J M, Cucca, F, Cupples, L A, Damrauer, S M, Davies, G, Deary, I J, Dedoussis, G, Denny, J C, Dominiczak, A, Dubé, M, Ebeling, T, Eiriksdottir, G, Esko, T, Farmaki, A, Feitosa, M F, Ferrario, M, Ferrieres, J, Ford, I, Fornage, M, Franks, P W, Frayling, T M, Frikke-schmidt, R, Fritsche, L G, Frossard, P, Fuster, V, Ganesh, S K, Gao, W, Garcia, M E, Gieger, C, Giulianini, F, Goodarzi, M O, Grallert, H, Grarup, N, Groop, L, Grove, M L, Gudnason, V, Hansen, T, Harris, T B, Hayward, C, Hirschhorn, J N, Holmen, O L, Huffman, J, Huo, Y, Hveem, K, Jabeen, S, Jackson, A U, Jakobsdottir, J, Jarvelin, M, Jensen, G B, Jørgensen, M E, Jukema, J W, Justesen, J M, Kamstrup, P R, Kanoni, S, Karpe, F, Kee, F, Khera, A V, Klarin, D, Koistinen, H A, Kooner, J S, Kooperberg, C, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T, Langenberg, C, Langsted, A, Launer, L J, Lauritzen, T, Liewald, D C M, Lin, L A, Linneberg, A, Loos, R J F, Lu, Y, Lu, X, Mägi, R, Malarstig, A, Manichaikul, A, Manning, A K, Mäntyselkä, P, Marouli, E, Masca, N G D, Maschio, A, Meigs, J B, Melander, O, Metspalu, A, Morris, A P, Morrison, A C, Mulas, A, Müller-nurasyid, M, Munroe, P B, Neville, M J, Nielsen, J B, Nielsen, S F, Nordestgaard, B G, Ordovas, J M, Mehran, R, O'donnell, C J, Orho-melander, M, Molony, C M, Muntendam, P, Padmanabhan, S, Palmer, C N A, Pasko, D, Patel, A P, Pedersen, O, Perola, M, Peters, A, Pisinger, C, Pistis, G, Polasek, O, Poulter, N, Psaty, B M, Rader, D J, Rasheed, A, Rauramaa, R, Reilly, D F, Reiner, A P, Renström, F, Rich, S S, Ridker, P M, Rioux, J D, Robertson, N R, Roden, D M, Rotter, J I, Rudan, I, Salomaa, V, Samani, N J, Sanna, S, Sattar, N, Schmidt, E M, Scott, R A, Sever, P, Sevilla, R S, Shaffer, C M, Sim, X, Sivapalaratnam, S, Small, K S, Smith, A V, Smith, B H, Somayajula, S, Southam, L, Spector, T D, Speliotes, E K, Starr, J M, Stirrups, K E, Stitziel, N, Strauch, K, Stringham, H M, Surendran, P, Tada, H, Tall, A R, Tang, H, Tardif, J, Taylor, K D, Trompet, S, Tsao, P S, Tuomilehto, J, Tybjaerg-hansen, A, Van Zuydam, N R, Varbo, A, Varga, T V, Virtamo, J, Waldenberger, M, Wang, N, Wareham, N J, Warren, H R, Weeke, P E, Weinstock, J, Wessel, J, Wilson, J G, Wilson, P W F, Xu, M, Yaghootkar, H, Young, R, Zeggini, E, Zhang, H, Zheng, N S, Zhang, W, Zhang, Y, Zhou, W, Zhou, Y, Zoledziewska, M, Howson, J M M, Danesh, J, Mccarthy, M I, Cowan, C A, Abecasis, G, Deloukas, P, Musunuru, K, Willer, C J & Kathiresan, S 2017, ' Exome-wide association study of plasma lipids in >300,000 individuals ', Nature Genetics, vol. 49, no. 12, pp. 1758–1766 . https://doi.org/10.1038/ng.3977Test
Nature Genetics, 49(12), 1758
Liu, D J, Peloso, G M, Yu, H, Butterworth, A S, Wang, X, Mahajan, A, Saleheen, D, Emdin, C, Alam, D, Alves, A C, Amouyel, P, Di Angelantonio, E, Arveiler, D, Assimes, T L, Auer, P L, Baber, U, Ballantyne, C M, Bang, L E, Benn, M, Bis, J C, Boehnke, M, Boerwinkle, E, Bork-Jensen, J, Bottinger, E P, Brandslund, I, Brown, M, Busonero, F, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y E, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Connell, J M, Cucca, F, Cupples, L A, Damrauer, S M, Davies, G, Grarup, N, Hansen, T, Jørgensen, M E, Lauritzen, T, Lin, L A, Nielsen, J B, Nielsen, S F, Pedersen, O, Pisinger, C, Zhang, Y & Charge Diabetes Working Group 2017, ' Exome-wide association study of plasma lipids in >300,000 individuals ', Nature Genetics, vol. 49, no. 12, pp. 1758-1766 . https://doi.org/10.1038/ng.3977Test
Nature Genetics, 49(12), 1758-1766. Nature Publishing Group
Nat. Genet. 49, 1758-1766 (2017)
Nature genetics

مصطلحات موضوعية: 0301 basic medicine, Exome/genetics, Genome-wide association study, Type 2 diabetes, Coronary Artery Disease, 030204 cardiovascular system & hematology, Bioinformatics, Charge Diabetes Working Group, Macular Degeneration, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Exome, Macular Degeneration/blood, Genetics & Heredity, Genetic Predisposition to Disease/genetics, CLONAL HEMATOPOIESIS, 11 Medical And Health Sciences, CODING-SEQUENCE VARIANTS, Lipids, Phenotype, CARDIOVASCULAR-DISEASE, VA Million Veteran Program, lipids (amino acids, peptides, and proteins), GOLD Consortium, LOW-FREQUENCY, EPIC-InterAct Consortium, Diabetes Mellitus, Type 2/blood, Life Sciences & Biomedicine, Type 2, medicine.medical_specialty, Genotype, APOBEC-1 COMPLEMENTATION FACTOR, Biology, Lower risk, Article, EPIC-CVD Consortium, GENETIC ARCHITECTURE, 03 medical and health sciences, Coronary Artery Disease/blood, Diabetes mellitus, Internal medicine, Genetics, medicine, Diabetes Mellitus, Journal Article, Lipolysis, Humans, Genetic Predisposition to Disease, Allele, TYROSINE KINASE JAK2, Genetic Association Studies, B MESSENGER-RNA, Science & Technology, MACULAR DEGENERATION, MYELOPROLIFERATIVE DISORDERS, Cholesterol, Lipids/blood, Genetic Variation, 06 Biological Sciences, medicine.disease, cardiovascular diseases, genome wide association studies, Genetic Association Studies/methods, 030104 developmental biology, Endocrinology, chemistry, Diabetes Mellitus, Type 2, TM6SF2, Developmental Biology

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030383a39967a21d7121379d9b90c713Test
http://hdl.handle.net/11383/2098126Test

المؤلفون: Dylan Aïssi, Claire Perret, Mathieu Lemire, Nora Zwingerman, Irfahan Kassam, Jessica Dennis, Vinh Truong, David-Alexandre Trégouët, Siying Huang, Philip S. Wells, Pierre-Emmanuel Morange, Michael D. Wilson

المساهمون: University of Toronto, Ontario Institute for Cancer Research [Canada] (OICR), Ontario Institute for Cancer Research, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [APHP], University of Ottawa [Ottawa] (uOttawa), Nutrition, obésité et risque thrombotique (NORT), Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), The Hospital for sick children [Toronto] (SickKids), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), University of Ottawa [Ottawa], HAL UPMC, Gestionnaire, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7, pp.11207. ⟨10.1038/s41598-017-09552-z⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, 2017, 7, pp.11207. ⟨10.1038/s41598-017-09552-z⟩

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Canada, lcsh:Medicine, Context (language use), Biology, [SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics, Bioinformatics, Methylation Site, Article, Epigenesis, Genetic, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, PHGDH Gene, Humans, Epigenetics, Phosphoglycerate dehydrogenase, Promoter Regions, Genetic, lcsh:Science, Gene, Phosphoglycerate Dehydrogenase, Triglycerides, ATP Binding Cassette Transporter, Subfamily G, Member 1, Family Health, Genetics, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Multidisciplinary, Triglyceride, lcsh:R, DNA Methylation, Middle Aged, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, 3. Good health, 030104 developmental biology, chemistry, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, DNA methylation, Female, lcsh:Q

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd189a4a7eb4d38397e14f78be78bd96Test
https://hal.sorbonne-universite.fr/hal-01609304Test

المؤلفون: Neil I. Bower, Katarzyna Koltowska, Kelly L. Betterman, Benjamin M. Hogan, Mathias Francois, Tara Karnezis, Jan Kazenwadel, Marc G. Achen, Philip S. Crosier, Jonathan W. Astin, Natasha L. Harvey, Steven A. Stacker, Emmanuelle Lesieur, Sonja Vermeren, Kelly A. Smith, Joelle Kartopawiro

المساهمون: Kartopawiro, Joëlle, Bower, Neil I, Karnezis, Tara, Kazenwadel, Jan, Betterman, Kelly L, Lesieur, Emmanuelle, Koltowska, Katarzyna, Astin, Jonathan, Crosier, Philip, Vermeren, Sonja, Achen, Marc G, Stacker, Steven A., Smith, Kelly A, Harvey, Natasha L, Francois, Mathias, Hogan, Benjamin M

المصدر: Human Molecular Genetics. 23:1286-1297

مصطلحات موضوعية: government.form_of_government, Vascular Endothelial Growth Factor C, Hypotrichosis, Mice, chemistry.chemical_compound, Cell Movement, SOXF Transcription Factors, Genetics, Lymphatic vessel, medicine, Animals, Lymphedema, Telangiectasis, Lymphangiogenesis, Molecular Biology, Zebrafish, Genetics (clinical), Adaptor Proteins, Signal Transducing, Lymphatic Vessels, Mice, Knockout, biology, GTPase-Activating Proteins, Endothelial Cells, Syndrome, General Medicine, biology.organism_classification, medicine.disease, Vascular endothelial growth factor, Disease Models, Animal, Lymphatic Endothelium, medicine.anatomical_structure, Lymphatic system, Gene Expression Regulation, Vascular endothelial growth factor C, chemistry, Hypotrichosis–lymphedema–telangiectasia syndrome, Immunology, Cancer research, government, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe2131cbb5597e028e36e88e8105be6Test
https://doi.org/10.1093/hmg/ddt518Test

المؤلفون: Ramakrishnan Karunakaran, M.E. Leonard, Bouchra Mouhsine, Alison K. East, J. Allan Downie, Allan Williams, Philip S. Poole, Marc A. Fox

مصطلحات موضوعية: Osmotic shock, Mutant, medicine.disease_cause, Microbiology, Rhizobium leguminosarum, chemistry.chemical_compound, Betaine, Bacterial Proteins, Operon, Genetics, medicine, Choline, Ammonium, Molecular Biology, biology, Membrane transport protein, Peas, Biological Transport, Gene Expression Regulation, Bacterial, Quaternary Ammonium Compounds, chemistry, Biochemistry, Glycine, Mutation, biology.protein, ATP-Binding Cassette Transporters

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1dde2bc652e7daf0b92b67b87349f44Test
https://ora.ox.ac.uk/objects/uuid:49d20bdb-e6b2-423a-b8e4-3e00b545489aTest

المؤلفون: Alicia C. Deng, Ronald J. Wong, Hui Zhao, Joshua M. Spin, Mark Hsu, Yosuke Kayama, Matthew B. Wallenstein, Flora Kalish, Takeshi Morisawa, Ronald L. Dalman, David K. Stevenson, Junya Azuma, Philip S. Tsao, Lars Maegdefessel

المساهمون: Bader, Michael

المصدر: PLoS ONE
PloS one, vol 11, iss 2
PLoS ONE, Vol 11, Iss 2, p e0149288 (2016)

مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, Swine, lcsh:Medicine, Gene Expression, 030204 cardiovascular system & hematology, Reductase, Cardiovascular, Biochemistry, Vascular Medicine, chemistry.chemical_compound, White Blood Cells, Mice, 0302 clinical medicine, Animal Cells, Genes, Reporter, Immune Physiology, Gene expression, Medicine and Health Sciences, 2.1 Biological and endogenous factors, Aetiology, Post-Translational Modification, lcsh:Science, Promoter Regions, Genetic, Heme, Pancreatic elastase, Aorta, Mice, Knockout, Innate Immune System, Multidisciplinary, Drugs, Animal Models, Lipids, Aortic Aneurysm, cardiovascular system, Disease Progression, Cytokines, Cellular Types, Anatomy, Inflammation Mediators, Aneurysms, Research Article, Statin, medicine.drug_class, General Science & Technology, Knockout, Immune Cells, Inflammatory Diseases, Immunology, Mouse Models, Biology, Research and Analysis Methods, Promoter Regions, 03 medical and health sciences, Enzyme activator, Rare Diseases, Model Organisms, Downregulation and upregulation, Genetic, medicine, Genetics, Animals, Abdominal, Vascular Diseases, Reporter, Pharmacology, Blood Cells, Animal, Macrophages, lcsh:R, Body Weight, Statins, Biology and Life Sciences, Proteins, Cell Biology, Molecular Development, Heme oxygenase, Enzyme Activation, Disease Models, Animal, 030104 developmental biology, Orphan Drug, chemistry, Genes, Immune System, Disease Models, Cancer research, Cardiovascular Anatomy, Blood Vessels, lcsh:Q, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Heme Oxygenase-1, Developmental Biology, Aortic Aneurysm, Abdominal

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8a44a4ee509fe07a49a16a84e32521Test
http://europepmc.org/articles/PMC4760983Test

المؤلفون: Takamasa Ishii, Philip S. Hartman, Naoaki Ishii

المصدر: Experimental Gerontology. 41:952-956

مصطلحات موضوعية: Genetically modified mouse, Aging, Protein subunit, Longevity, Mutant, Mice, Transgenic, Mitochondrion, Biology, medicine.disease_cause, Biochemistry, Mice, chemistry.chemical_compound, Endocrinology, Superoxides, Neoplasms, Genetics, medicine, Animals, Humans, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Molecular Biology, Mutation, Superoxide, Electron Transport Complex II, Membrane Proteins, 3T3 Cells, Cell Biology, Cytochromes b, Molecular biology, Mitochondria, Cell biology, Succinate Dehydrogenase, Oxidative Stress, chemistry, Apoptosis, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a0a39ac442cf2252e0f23129c9c836Test
https://doi.org/10.1016/j.exger.2006.06.037Test