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المؤلفون: Lachlan Clydesdale, Hari Venugopal, Peishen Zhao, Patrick M. Sexton, Alisa Glukhova, Arthur Christopoulos, Christopher A. Reynolds, Yi Lynn Liang, Xin Zhang, Tin T. Truong, Andrew N. Keller, Maryam Khoshouei, Matthew J. Belousoff, Karen J. Gregory, Giuseppe Deganutti, Radostin Danev, Denise Wootten, Katie Leach
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Nature Communicationsمصطلحات موضوعية: Protein Conformation, alpha-Helical, Gene Expression, General Physics and Astronomy, Peptide, Ligands, chemistry.chemical_compound, Receptor pharmacology, G protein-coupled receptors, Glucagon-Like Peptide 1, Cloning, Molecular, Receptor, chemistry.chemical_classification, Multidisciplinary, digestive, oral, and skin physiology, Recombinant Proteins, Transmembrane domain, Oxyntomodulin, Baculoviridae, hormones, hormone substitutes, and hormone antagonists, Protein Binding, Agonist, endocrine system, medicine.drug_class, G protein, Science, Genetic Vectors, Allosteric regulation, Molecular Dynamics Simulation, Glucagon-Like Peptide-1 Receptor, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, Allosteric Regulation, Electron microscopy, medicine, Humans, Protein Interaction Domains and Motifs, Binding Sites, Cryoelectron Microscopy, Mutagenesis, General Chemistry, Kinetics, HEK293 Cells, chemistry, Mutation, Biophysics, Exenatide, Protein Conformation, beta-Strand
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5aa9dcac923a091ce55a4b69969de5Test
https://doaj.org/article/8f7e8894b23a4f8eb32f5d2c26ccefc6Test -
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المؤلفون: Giuseppe Deganutti, Silvia Atanasio, Roxana-Maria Rujan, Patrick M. Sexton, Denise Wootten, Christopher A. Reynolds
المصدر: Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciencesمصطلحات موضوعية: Agonist, binding, medicine.drug_class, QH301-705.5, Peptide, Calcitonin gene-related peptide, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, GPCR, medicine, Molecular Biosciences, CGRP, Biology (General), Receptor, Molecular Biology, Original Research, G protein-coupled receptor, chemistry.chemical_classification, Telcagepant, telcagepant, Chemistry, molecular dynamics, Cell biology, Docking (molecular), RAMP1, supervised molecular dynamics, CGRPR
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c8a9e43e55937087396fb35c958567Test
https://www.frontiersin.org/articles/10.3389/fmolb.2021.720561/fullTest -
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المؤلفون: Michael Morris, A. K. Jones, Oliver J. Hale, Nick Taylor, Rainer Cramer, Christopher K. Reynolds, Cristian Piras
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reportsمصطلحات موضوعية: Proteomics, 0301 basic medicine, Traceability, Science, media_common.quotation_subject, Mass spectrometry, Biochemistry, 01 natural sciences, Article, Cow milk, 03 medical and health sciences, media_common, Adulterant, Profiling (computer programming), chemistry.chemical_classification, Multidisciplinary, Chromatography, Chemistry, Biomolecule, Biological techniques, 010401 analytical chemistry, Proteins, Lipids, 0104 chemical sciences, Speciation, 030104 developmental biology, Medicine, Food quality
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ab9a5f0d89d7f9c4d6ff2f8b5033adTest
https://doi.org/10.1038/s41598-021-82846-5Test -
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المؤلفون: Christopher K. Reynolds, Alistair S. Grandison, R. Morgan, Kirsty E. Kliem, David J. Humphries, D.I. Givens, Katherine M. Livingstone
المصدر: Journal of Dairy Science. 102:288-300
مصطلحات موضوعية: Whey protein, Rumen, Rapeseed, Total mixed ration, 03 medical and health sciences, fluids and secretions, Latin square, Genetics, Animals, Lactation, Food science, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Chemistry, Fatty Acids, 0402 animal and dairy science, food and beverages, 04 agricultural and veterinary sciences, Animal Feed, 040201 dairy & animal science, Diet, Milk, Whey Proteins, Dietary Supplements, Fermentation, Cattle, Female, Rapeseed Oil, Animal Science and Zoology, Composition (visual arts), Food Science, Polyunsaturated fatty acid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3275149e080f3b7e3c04b89a6f6e937bTest
https://doi.org/10.3168/jds.2018-15247Test -
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المصدر: Animal, Vol 13, Iss 3, Pp 524-532 (2019)
مصطلحات موضوعية: Rumen, 040301 veterinary sciences, Silage, Forage, CHOP, Poaceae, SF1-1100, 0403 veterinary science, Animal science, Latin square, chop length, Animals, Lactation, Dry matter, particle size distribution, Particle Size, milk production, ryegrass silage, chemistry.chemical_classification, Chemistry, 0402 animal and dairy science, food and beverages, 04 agricultural and veterinary sciences, Metabolism, Hydrogen-Ion Concentration, 040201 dairy & animal science, forage ratio, Diet, Animal culture, Milk, Fatty Acids, Unsaturated, Animal Science and Zoology, Animal Nutritional Physiological Phenomena, Cattle, Female, Polyunsaturated fatty acid
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888018589cd66b262f8f02378c2ac3a4Test
http://www.sciencedirect.com/science/article/pii/S1751731118001568Test -
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المؤلفون: Arthur Christopoulos, Sebastian G.B. Furness, Yi Lynn Liang, Giuseppe Deganutti, Matthew J. Belousoff, Maoqing Dong, Christopher A. Reynolds, Alisa Glukhova, Sarah J. Piper, Radostin Danev, Patrick M. Sexton, Maryam Khoshouei, Denise Wootten, Kaleeckal G. Harikumar, Laurence J. Miller
المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Insecta, General Physics and Astronomy, Peptide, 02 engineering and technology, Plasma protein binding, Crystallography, X-Ray, Protein Structure, Secondary, Receptors, G-Protein-Coupled, Secretin, Protein structure, Cricetinae, GTP-Binding Protein alpha Subunits, Gs, lcsh:Science, Peptide sequence, chemistry.chemical_classification, Multidisciplinary, Chemistry, Gastroenterology, 021001 nanoscience & nanotechnology, Structural biology, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, hormones, hormone substitutes, and hormone antagonists, Protein Binding, Science, Protein domain, Molecular Dynamics Simulation, digestive system, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, Protein Domains, Animals, Humans, Amino Acid Sequence, Cysteine, G protein-coupled receptor, Binding Sites, Cryoelectron Microscopy, Hydrogen Bonding, General Chemistry, 030104 developmental biology, Biophysics, lcsh:Q
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d095ff17c121c4e6cf026f4b65f53375Test
https://doi.org/10.1038/s41467-020-17791-4Test -
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المؤلفون: Giovanna Ghirlanda, Patrick M. Sexton, Juliana E. Milburn, Arthur Christopoulos, Maoqing Dong, Denise Wootten, Christopher A. Reynolds, Rafael Alcala-Torano, Juan Carlos Mobarec, Carolyn E. Clark, Sweta R. Raval, Kaleeckal G. Harikumar, Laurence J. Miller
المصدر: Biochem Pharmacol
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Conformation, alpha-Helical, Peptide, CHO Cells, Ligands, Biochemistry, Partial agonist, Article, Glucagon-Like Peptide-1 Receptor, Receptors, G-Protein-Coupled, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, 0302 clinical medicine, Cricetulus, Secretin, Animals, Humans, Amino Acid Sequence, Receptor, G protein-coupled receptor, Pharmacology, chemistry.chemical_classification, Alanine, Binding Sites, Biological activity, Receptors, Calcitonin, Ligand (biochemistry), 030104 developmental biology, chemistry, Competitive antagonist, 030220 oncology & carcinogenesis, Drug Design, Biophysics, Secretin receptor, Peptides, Hydrophobic and Hydrophilic Interactions, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1704710372a14db4f7d2b7f9b7a4caTest
https://europepmc.org/articles/PMC7299832Test/ -
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المؤلفون: Christopher K. Reynolds, A.L. Thomson, J.E. Archer, N.W. Grant, Caroline Rymer, David J. Humphries
المصدر: Animal Feed Science and Technology. 239:94-106
مصطلحات موضوعية: chemistry.chemical_classification, Silage, 0402 animal and dairy science, food and beverages, 04 agricultural and veterinary sciences, Fractionation, 040201 dairy & animal science, Nutrient, Animal science, chemistry, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, Animal Science and Zoology, Organic matter, Composition (visual arts), Dry matter, Animal nutrition, Chemical composition, Mathematics
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d55ec708ab7eb1367e5c50d0144a72Test
https://doi.org/10.1016/j.anifeedsci.2018.03.009Test -
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المؤلفون: Paul W. R. Harris, Renata Kowalczyk, Daniel P. Raleigh, Christopher A. Reynolds, Augen A. Pioszak, Giuseppe Deganutti, Amy G. Wong, Erica R. Hendrikse, Christopher S. Walker, Katarzyna Swierkula, Lauren R. Yule, Rebekah L. Bower, Margaret A. Brimble, Zachary Ridgway, Debbie L. Hay, Tayla A Rees
المصدر: ACS Pharmacology & Translational Science. 1:32-49
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, chemistry.chemical_classification, endocrine system, Amylin, Peptide, Calcitonin gene-related peptide, Peptide hormone, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, chemistry, Pharmacology (medical), Calcitonin receptor, Signal transduction, Receptor, 030217 neurology & neurosurgery, G protein-coupled receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73e05cc00f40f537ec5c0918e4a81aaTest
https://doi.org/10.1021/acsptsci.8b00002Test -
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المؤلفون: Caroline A. Hick, Emma Dal Maso, Patrick M. Sexton, Giuseppe Deganutti, Denise Wootten, Ming-Wei Wang, Sebastian G.B. Furness, Debbie L. Hay, Christopher A. Reynolds, Arthur Christopoulos, Vi Pham, Yue Zhu, Dehua Yang
المصدر: Biochemical Pharmacology
مصطلحات موضوعية: 0301 basic medicine, Agonist, endocrine system, medicine.drug_class, Receptor expression, GPCR structure-function, Peptide, Biased agonism, Biochemistry, Protein Structure, Secondary, Article, Cell Line, 03 medical and health sciences, medicine, Functional selectivity, Humans, Amino Acid Sequence, G protein-coupled receptor, Calcitonin receptor, Receptor, ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Chemistry, Extracellular Fluid, Receptors, Calcitonin, Peptide Fragments, Protein Structure, Tertiary, 3. Good health, Cell biology, 030104 developmental biology, Calcitonin, Molecular modelling, hormones, hormone substitutes, and hormone antagonists, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc96dc5c8c6251a26201fc893b221aaTest
https://doi.org/10.1016/j.bcp.2018.02.005Test