المؤلفون: Van de Walle, Tim, Cools, Lore, Mangelinckx, Sven, D'hooghe, Matthias

المصدر: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ; ISSN: 0223-5234 ; ISSN: 1768-3254

مصطلحات موضوعية: Chemistry, Medicine and Health Sciences, Organic Chemistry, Drug Discovery, Pharmacology, General Medicine, Quinoline, Malaria, Cancer, Medicinal chemistry, PLASMODIUM-FALCIPARUM MALARIA, TYROSINE KINASE INHIBITORS, COLCHICINE BINDING-SITE, BETA-HEMATIN FORMATION, IN-VITRO, BIOLOGICAL EVALUATION, ANTIPROLIFERATIVE ACTIVITY, TOPOISOMERASE-I, CANCER-THERAPY, GUANYLTHIOUREA DERIVATIVES

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

العلاقة: https://biblio.ugent.be/publication/8730417Test; http://hdl.handle.net/1854/LU-8730417Test; http://dx.doi.org/10.1016/j.ejmech.2021.113865Test; https://biblio.ugent.be/publication/8730417/file/8730420Test

الإتاحة: https://doi.org/10.1016/j.ejmech.2021.113865Test
https://biblio.ugent.be/publication/8730417Test
http://hdl.handle.net/1854/LU-8730417Test
https://biblio.ugent.be/publication/8730417/file/8730420Test

المؤلفون: Vandekerckhove, Stephanie, D'hooghe, Matthias

المصدر: BIOORGANIC & MEDICINAL CHEMISTRY ; ISSN: 0968-0896

مصطلحات موضوعية: Chemistry, Hybrids, Quinolines, Antimalarial agents, CHLOROQUINE-RESISTANCE TRANSPORTER, HISTONE DEACETYLASE INHIBITORS, PLASMODIUM-FALCIPARUM MALARIA, ANTI-TUBERCULAR EVALUATION, CINNAMIC ACID-DERIVATIVES, CYCLOADDITION EN-ROUTE, BETA-LACTAM-FERROCENE, IN-VITRO, BIOLOGICAL EVALUATION, ANTIPLASMODIAL ACTIVITY

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

العلاقة: https://biblio.ugent.be/publication/7070616Test; http://hdl.handle.net/1854/LU-7070616Test; http://dx.doi.org/10.1016/j.bmc.2014.12.018Test; https://biblio.ugent.be/publication/7070616/file/7070624Test

الإتاحة: https://doi.org/10.1016/j.bmc.2014.12.018Test
https://biblio.ugent.be/publication/7070616Test
http://hdl.handle.net/1854/LU-7070616Test
https://biblio.ugent.be/publication/7070616/file/7070624Test

المؤلفون: Qiuying Cheng, John M. Ong'echa, Angela O. Achieng, Bernard Guyah, Collins Ouma, Christophe G. Lambert, Douglas J Perkins

المصدر: EBioMedicine

مصطلحات موضوعية: Male, 0301 basic medicine, Research paper, medicine.medical_treatment, Interleukin-1beta, PBMCs, Peripheral blood mononuclear cells, LAIR2, Leukocyte-associated immunoglobulin like receptor-2, PfHz, Plasmodium falciparum haemozoin, LAIR1, Leukocyte-associated immunoglobulin like receptor-1, SHP-1, SH2 domain-containing tyrosine phosphatase-1, Pathogenesis, chemistry.chemical_compound, 0302 clinical medicine, PCN, Pigment containing neutrophils, TNF-α, Tumor necrosis factor alpha, Malaria, Falciparum, Receptors, Immunologic, 050207 economics, Receptor, Leukocyte-associated immunoglobulin like receptor-1, Leukocyte-associated immunoglobulin like receptor-2, P. falciparum, Plasmodium falciparum, 050208 finance, CLL, Chronic lymphocytic leukaemia, ITIM, immuno-tyrosine inhibition motifs, biology, Protein Tyrosine Phosphatase, Non-Receptor Type 6, 05 social sciences, Anemia, General Medicine, SMA, Severe malarial anaemia, 3. Good health, HFRS, haemorrhagic fever with renal syndrome, Child, Preschool, HIV-1, Human immunodeficiency virus 1, 030220 oncology & carcinogenesis, IL-6, Interleukin 6, Female, Tumor necrosis factor alpha, Antibody, Signal Transduction, C1q, Complement component 1q, Hemeproteins, SHP-2, SH2 domain-containing tyrosine phosphatase-2, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Immune system, Phagocytosis, SLE, Systemic lupus erythematosus, Complement component 1q, In vivo, 0502 economics and business, medicine, Humans, SMA, severe malarial anaemia, Interleukin 6, Plasmodium falciparum malaria, Interleukin-6, Tumor Necrosis Factor-alpha, business.industry, Complement C1q, LAIR1, Plasmodium falciparum haemozoin, Antagonist, Infant, PCM, Pigment containing monocytes, NF-κB, Immunotherapy, AML, Acute myeloid leukaemia, 030104 developmental biology, chemistry, NF-κB, Nuclear factor-kappa beta, Immunology, Leukocytes, Mononuclear, IL-1β, Interleukin 1 beta, biology.protein, PCR, Polymerase chain reaction, business, Biomedical sciences

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30abf7c3e7fb40fd277a58e163bf6e21Test
https://doi.org/10.1016/j.ebiom.2019.06.040Test

المؤلفون: Aziz, Mohd Yusmaidie, 1984, Hoffmann, Kurt-Jürgen, Ashton, Michael, 1955

المصدر: Journal of Pharmaceutical Sciences. 107(5):1461-1467

مصطلحات موضوعية: Chemical Sciences, Kemi, Pharmacology and Toxicology, Farmakologi och toxikologi, piperaquine, CYP inhibition, drug-drug interaction, drug-drug interactions, plasmodium-falciparum malaria, mechanism-based, inhibition, time-dependent inhibition, in-vitro, dihydroartemisinin-piperaquine, clinical-trial, pharmacokinetics, midazolam, cytochromes-p450, Pharmacology & Pharmacy, Chemistry

الوصول الحر: https://gup.ub.gu.se/publication/267678Test

المؤلفون: Nicholas J. White, Mara K. N. Lawniczak, Darunee Chiwcharoen, Kathrin Witmer, Arjen M. Dondorp, Kesinee Chotivanich, Oliver J Watson, Virginia M. Howick, Jake Baum, Lucy C Okell, Richard D. Pearson, Michael J. Delves, Andrea Ruecker, Farah A. Dahalan, Boodtee Sornboon, Sasithon Pukrittayakamee, Sabrina Yahiya, Ursula Straschil

المساهمون: Intensive Care Medicine, Wellcome Trust, Medicines for Malaria Venture, Medical Research Council (MRC), The Royal Society

المصدر: Antimicrobial Agents and Chemotherapy
Antimicrobial agents and chemotherapy, 65(1):e00898-20. American Society for Microbiology

مصطلحات موضوعية: Male, medicine.medical_treatment, Artemisinin combination therapies (ACTs), Drug Resistance, Gametocytes, chemistry.chemical_compound, 1108 Medical Microbiology, Pharmacology (medical), Pharmacology & Pharmacy, Artemisinin, Malaria, Falciparum, SOUTHEAST-ASIA, Asia, Southeastern, 0303 health sciences, Multidrug-resistant malaria, OPEN-LABEL, Artemisinins, 3. Good health, Kelch13, Infectious Diseases, DIHYDROARTEMISININ, MEFLOQUINE RESISTANCE, Anopheles stephensi, 1115 Pharmacology and Pharmaceutical Sciences, Life Sciences & Biomedicine, medicine.drug, 0605 Microbiology, Combination therapy, ARTESUNATE, Plasmodium falciparum, Dihydroartemisinin, PFMDR1 GENE, Biology, Microbiology, 03 medical and health sciences, Antimalarials, Halofantrine, Mechanisms of Resistance, parasitic diseases, medicine, Gametocyte, Animals, Humans, HALOFANTRINE, Parasites, COMBINATION, 030304 developmental biology, Pharmacology, Science & Technology, 030306 microbiology, PLASMODIUM-FALCIPARUM MALARIA, biology.organism_classification, medicine.disease, Virology, Culicidae, chemistry, Artesunate, Transmission blocking, Malaria

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222babf9a1a4a841550f7ebef07a8deaTest
https://doi.org/10.1128/aac.00898-20Test

المؤلفون: Ahmed Abdalazim Dafallah Albashir

المصدر: Oxford Medical Case Reports

مصطلحات موضوعية: myalgia, Pediatrics, medicine.medical_specialty, Constipation, 030231 tropical medicine, Case Report, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, parasitic diseases, Medicine, 030212 general & internal medicine, functional intestinal obstruction, Plasmodium falciparum malaria, biology, business.industry, Anopheles, Plasmodium falciparum, Functional Bowel Obstruction, biology.organism_classification, medicine.disease, omcrep/1200, intestinal obstruction, Bowel obstruction, Infectious Diseases, chemistry, Artesunate, Parasitology, medicine.symptom, business, AcademicSubjects/MED00010, Malaria

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f20cd6b0d819e7b9d3a1c79776e1dadTest
http://europepmc.org/articles/PMC7583405Test

المؤلفون: Lore Cools, Sven Mangelinckx, Matthias D'hooghe, Tim Van de Walle

المصدر: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

مصطلحات موضوعية: CANCER-THERAPY, Quinoline, Antineoplastic Agents, Medicinal chemistry, Antimalarials, Neoplasms, Drug Discovery, Medicine and Health Sciences, TYROSINE KINASE INHIBITORS, Humans, Antimalarial Agent, BIOLOGICAL EVALUATION, Cancer, Pharmacology, BETA-HEMATIN FORMATION, Molecular Structure, Traditional medicine, ANTIPROLIFERATIVE ACTIVITY, Chemistry, Organic Chemistry, Plasmodium parasite, PLASMODIUM-FALCIPARUM MALARIA, IN-VITRO, General Medicine, Anticancer drug, TOPOISOMERASE-I, Malaria, COLCHICINE BINDING-SITE, Quinolines, GUANYLTHIOUREA DERIVATIVES

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173ca6cff8efb356d1ba46c8277528fdTest
https://doi.org/10.1016/j.ejmech.2021.113865Test

المؤلفون: Elizabeth Juma, Azra C. Ghani, Raquel González, Michael T. Bretscher, Sarah G. Staedke, Philippe J Guerin, Bertrand Lell, Umberto D'Alessandro, Elisabeth Baudin, Kasia Stepniewska, Emmanuelle Espie, Innocent Valea, Clarissa Moreira, Halidou Tinto, Clara Menéndez, Estrella Lasry, Abdoulaye Djimde, Nines Lima, Jamie T. Griffin, Jean-Bosco Ouédraogo, Lucy C Okell, Grant Dorsey, Ghyslain Mombo-Ngoma, Frederic Nikiema, Adoke Yeka, Quique Bassat, Corine Karema, Prabin Dahal, Bakary Fofana

المساهمون: Medical Research Council (MRC), Medicines for Malaria Venture, The Royal Society, Bill & Melinda Gates Foundation

المصدر: BMC Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
BMC Med
BMC Medicine
Dipòsit Digital de la UB
Universidad de Barcelona

مصطلحات موضوعية: 0301 basic medicine, Male, SELECTION, Artemether/lumefantrine, lcsh:Medicine, Trial, chemistry.chemical_compound, 0302 clinical medicine, Mathematical model, mdr1, Artemisinin, Malaria, Falciparum, 11 Medical and Health Sciences, biology, Artesunate/amodiaquine, General Medicine, Artemisinins, 3. Good health, Drug Combinations, Child, Preschool, Chemoprophylaxis, Crt, Female, Drug, Life Sciences & Biomedicine, PREGNANT-WOMEN, medicine.drug, Research Article, CHEMOPREVENTION, medicine.medical_specialty, 030231 tropical medicine, 030106 microbiology, Plasmodium falciparum, Malària, MOLECULAR MARKERS, Amodiaquine, GENETIC-STRUCTURE, Lumefantrine, 03 medical and health sciences, Antimalarials, Medicine, General & Internal, Internal medicine, General & Internal Medicine, parasitic diseases, medicine, Humans, DIHYDROARTEMISININ-PIPERAQUINE, ANTIMALARIAL-DRUG RESISTANCE, POLYMORPHISMS, Science & Technology, business.industry, Artemether, Lumefantrine Drug Combination, lcsh:R, Infant, PLASMODIUM-FALCIPARUM MALARIA, medicine.disease, biology.organism_classification, Malaria, chemistry, business, SULFADOXINE-PYRIMETHAMINE

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b428836411d235e5beb84c0efc8eb8Test
http://hdl.handle.net/10044/1/76878Test

المؤلفون: Aziz, Mohd Yusmaidie, 1984, Hoffmann, Kurt-Jürgen, Ashton, Michael, 1955

المصدر: Journal of chromatography. B. 1063:253-258

مصطلحات موضوعية: Biochemistry and Molecular Biology, Biokemi och molekylärbiologi, Pharmacology and Toxicology, Farmakologi och toxikologi, Chemical Sciences, Kemi, Piperaquine, Malaria, LC-MS/MS, Pharmacokinetics, Drug metabolism, plasmodium-falciparum malaria, dihydroartemisinin-piperaquine, artemether-lumefantrine, uncomplicated malaria, pharmacokinetics, children, Biochemistry & Molecular Biology, Chemistry

الوصول الحر: https://gup.ub.gu.se/publication/258756Test

المؤلفون: Aung Pyae Phyo, Nicholas J. White, François Nosten, Atthanee Jeeyapant, Marina Mc Dew White, Verena I. Carrara, Nicholas P. J. Day, Kamonchanok Konghahong, Charles J. Woodrow, Kanlaya Sriprawat, Tim J. Anderson, Clare L. Ling, Jerzy Michal Dziekan, Shalini Nair, Elizabeth A. Ashley, Mallika Imwong, Zbynek Bozdech, Khin Maung Lwin, Rose McGready, Stephane Proux

المصدر: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Combination therapy, 030106 microbiology, Population, Plasmodium falciparum, Drug Resistance, Protozoan Proteins, Drug resistance, artemisinin resistance, 03 medical and health sciences, chemistry.chemical_compound, Antimalarials, parasitic diseases, medicine, Humans, Artemisinin, Malaria, Falciparum, education, Articles and Commentaries, Pfmdr1, education.field_of_study, Plasmodium falciparum malaria, biology, Mefloquine, business.industry, K13 mutation, medicine.disease, biology.organism_classification, Virology, Artemisinins, 3. Good health, Infectious Diseases, chemistry, Artesunate, Mutation, business, Malaria, medicine.drug, mefloquine–artesunate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c908aa0001d2f632ac701c710d89ab3Test
http://europepmc.org/articles/PMC4996140Test