المؤلفون: Raidan Ba-Hattab, Noha Barhom, Safa A. Azim Osman, Iheb Naceur, Aseel Odeh, Arisha Asad, Shahd Ali R. N. Al-Najdi, Ehsan Ameri, Ammar Daer, Renan L. B. Da Silva, Claudio Costa, Arthur R. G. Cortes, Faleh Tamimi

المصدر: Applied Sciences, Vol 13, Iss 3, p 1516 (2023)

مصطلحات موضوعية: artificial intelligence, neural network, periapical lesion, panoramic radiographs, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

الوصف: Dentists could fail to notice periapical lesions (PLs) while examining panoramic radiographs. Accordingly, this study aimed to develop an artificial intelligence (AI) designed to address this problem. Materials and methods: a total of 18618 periapical root areas (PRA) on 713 panoramic radiographs were annotated and classified as having or not having PLs. An AI model consisting of two convolutional neural networks (CNNs), a detector and a classifier, was trained on the images. The detector localized PRAs using a bounding-box-based object detection model, while the classifier classified the extracted PRAs as PL or not-PL using a fine-tuned CNN. The classifier was trained and validated on a balanced subset of the original dataset that included 3249 PRAs, and tested on 707 PRAs. Results: the detector achieved an average precision of 74.95%, while the classifier accuracy, sensitivity and specificity were 84%, 81% and 86%, respectively. When integrating both detection and classification models, the proposed method accuracy, sensitivity, and specificity were 84.6%, 72.2%, and 85.6%, respectively. Conclusion: a two-stage CNN model consisting of a detector and a classifier can successfully detect periapical lesions on panoramic radiographs.

العلاقة: https://www.mdpi.com/2076-3417/13/3/1516Test; https://doaj.org/toc/2076-3417Test; https://doaj.org/article/c028f1d1e51044658629825c05fbf480Test

الإتاحة: https://doi.org/10.3390/app13031516Test
https://doaj.org/article/c028f1d1e51044658629825c05fbf480Test

المؤلفون: Hye-Mi Jeon, Youn-Kyung Choi, Jeong-Kil Park, So-Yeun Kim, Kyoung-Hwa Jung, Eun Young Kwon

المصدر: Journal of Dental Rehabilitation and Applied Science. 37:95-100

مصطلحات موضوعية: Periapical lesion, chemistry.chemical_compound, Calcium hydroxide, chemistry, business.industry, Medicine, Dentistry, Radiation treatment planning, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c2b9c46f57c00230fbc943637dbb1548Test
https://doi.org/10.14368/jdras.2021.37.2.95Test

المؤلفون: Lamya Mohammed Alhomaidhi

المصدر: International Journal of Medicine in Developing Countries. :403-406

مصطلحات موضوعية: biology, business.industry, Dentistry, Case presentation, Gutta-percha, biology.organism_classification, Periapical lesion, Mandibular canine, chemistry.chemical_compound, chemistry, Rooted tooth, Sodium hypochlorite, Medicine, business, Root canal anatomy, Endodontic retreatment

الوصف: Background: The knowledge of root canal anatomy is considered essential in the diagnoses and treatment of endodontic cases to assure successful outcomes. Although the mandibular canine is known to be a single- rooted tooth with a single canal, variations can be seen. However, the incidence of a mandibular canine having two roots and two canals is extremely rare. Case Presentation: This article reports a case of non-surgical retreatment of mandibular canine, with two roots and two canals, presented to the clinic with a periapical lesion. Chloroform and H-files were used to remove previous gutta percha, canals were shaped with a profile rotary system, and irrigated with 2.5% sodium hypochlorite. The canals were then obturated with gutta percha and AH Plus sealer. Conclusion: Clinicians must use all the available tools to help them detect anatomical variations to manage their cases successfully.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0942b19e50c207d3bc3399b094992168Test
https://doi.org/10.24911/ijmdc.51-1606133450Test

المؤلفون: Deebah Choudhary, Atinderpal Singh, Nikhil Dev Wazir

المصدر: IP Indian Journal of Conservative and Endodontics. 5:123-126

مصطلحات موضوعية: Endodontic therapy, 030219 obstetrics & reproductive medicine, Calcium hydroxide, Surgical approach, Periapical radiolucency, business.industry, Periapical disease, Inflammatory response, Dentistry, 030206 dentistry, Lesion, Periapical lesion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, medicine, medicine.symptom, business

الوصف: Background: Periapical disease may occur through an inflammatory response in a non-vital tooth. The treatment of choice for most of these periapical lesions may be a conservative non-surgical approach. An accurate diagnosis of the periapical lesion whether it is of endodontic or nonendodontic origin has to be made. Non- surgical endodontic therapy has shown a success rate of 94.4% with complete or partial healing. Case description: The present clinical cases show two large periapical lesions in 14 year and 17-year-old male patients respectively which were healed with non- surgical approaches using different formulations of calcium hydroxide. Conclusion: Healing was seen after few months in both the lesion without invasive treatments. As the first case revealed periapical healing within 2 months of calcium hydroxide placement whereas the second case showed a much slower rate of healing over one year. Keywords: Nonsurgical treatment, Periapical lesion, Calcium hydroxide, Metapex.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::82cf55edc2df7590ba8a363e31a7cac4Test
https://doi.org/10.18231/j.ijce.2020.029Test

المؤلفون: Harees Shabir, Avninder Kaur, Anchal Soni

المصدر: Dental Journal of Advance Studies. 8:127-130

مصطلحات موضوعية: Periodontitis, medicine.diagnostic_test, business.industry, Dentistry, Physical examination, 030206 dentistry, medicine.disease, Periapical lesion, stomatognathic diseases, 03 medical and health sciences, Cementoenamel junction, chemistry.chemical_compound, 0302 clinical medicine, stomatognathic system, Discolored tooth, chemistry, 030220 oncology & carcinogenesis, Sodium hypochlorite, medicine, business, Pulp necrosis, Permanent teeth

الوصف: A 9-year-old child reported with chief complaint of broken teeth (11 and 21) and discolored tooth (21). Diagnosis of pulp necrosis with apical periodontitis with regard to 11 and 21 was made based on clinical and radiographic examination. The canals were irrigated with sodium hypochlorite and then dried with paper points. Disinfection of canals was done using photoactivated disinfection (PAD). Platelet-rich fibrin (PRF) was placed as scaffold in canals till the cementoenamel junction (CEJ). A 2-mm thick layer of white MTA was placed, followed by dual seal using glass–ionomer cement (GIC) and composite resin. Follow-up examination was done for 1 year. Clinical examination showed no pain, tenderness on percussion, and no mobility and improvement in color of teeth. Radiographic evaluation revealed continued thickening of the dentinal walls, root lengthening, regression of the periapical lesion, and partial apical closure. This report of pulp revascularization shows that disinfection with photodynamic therapy combined with PRF resulted in satisfactory root development in necrotic immature teeth.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d5fafcee074341becd84c1c58af20144Test
https://doi.org/10.1055/s-0040-1714157Test

المؤلفون: Rahmi Alma Farah, Myrna Nurlatifah Zakaria, Elvi Sahara

المصدر: Key Engineering Materials. 829:226-231

مصطلحات موضوعية: Calcium hydroxide, business.industry, Mechanical Engineering, Dentistry, 030206 dentistry, Periapical lesion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Mechanics of Materials, General Materials Science, 030212 general & internal medicine, business, Pulp necrosis

الوصف: Calcium hydroxide [Ca(OH)2] has been widely used as an intracanal medicament especially in treatment of periapical lesion. This case report will discuss about calcium hydroxide as intracanal medicament in a periapical lesion of an upper left central incisor. This case describes about treatment of periapical lesion with suspect of infected cyst with symptoms and root resorption. Root canal preparation was done by crown down technique using protaper hands universal from S1/27mm until F5/27mm. Calcium hydroxide paste was continuously applicated every 2 weeks as intracanal medicament until the periapical index (PAI) of lesion decrease, in this case PAI decreased from scale 5 until scale 2 during three months recall. Calcium hydroxide supports tissue repair, stimulates fibroblast formation and damage the cytoplasmic membrane of bacteria, denature their proteins or damage the DNA by its alkaline property. As conclusion, the use of calcium hydroxide successfully decrease the periapical lesion index in the periapical radiograph examination and can be considered as a simple and effective medicament for endodontic infection.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8f9bdd441c5b6e12054eecb957df6f02Test
https://doi.org/10.4028/www.scientific.net/kem.829.226Test

المؤلفون: Recai Zan, Fatma Kaya, Kerem Engin Akpinar, Demet Altunbaş

المصدر: Volume: 23, Issue: 3 248-253
Cumhuriyet Dental Journal

مصطلحات موضوعية: Calcium hydroxide, business.industry, Root canal, Dentistry, Periapical lesion, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Healing,large periapical lesion,non-surgical endodontic treatment,calcium hydroxide, Health Care Sciences and Services, General Earth and Planetary Sciences, Medicine, Sağlık Bilimleri ve Hizmetleri, business, General Environmental Science

الوصف: The infected pulp, microorganisms toxins, metabolic products, chemical agents, mechanical irritations, foreign substances, trauma and host defense plays a role in the periapical tissue diseases. Options for the treatment of large periapical lesions range from non-surgical root canal treatment and/or apical surgery to extraction. Although apical surgery may be a treatment option in these cases, conventional root canal treatment should be the first choice. The aim of this case report is to report that the large size of a periapical lesion does not always need a surgical approach and even large periapical lesions heal following a conservative endodontic therapy.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06d79357fa5203dac751137de287c73Test
https://dergipark.org.tr/tr/pub/cumudj/issue/56988/694557Test

المؤلفون: Iago Ramirez, Naiana Viana Viola, Giovanni Antônio Nícoli, Suellen de Azevedo Moreira, Camila Soares Lopes

المساهمون: Universidade Estadual Paulista (Unesp), Univ Fed Alfenas

المصدر: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

مصطلحات موضوعية: Tooth injury, medicine.medical_specialty, Periapical cyst, Sodium Hypochlorite, medicine.medical_treatment, Biophysics, Dentistry, Photodynamic therapy, Dermatology, Endodontics, Root Canal Filling Materials, Lesion, chemistry.chemical_compound, Dental Pulp Necrosis, medicine, Humans, Pharmacology (medical), Calcium hydroxide, Antimicrobial photodynamic therapy, Root Canal Irrigants, business.industry, Biofilm, medicine.disease, Root Canal Therapy, Disinfection, Periapical lesion, Photochemotherapy, Oncology, chemistry, Debridement (dental), medicine.symptom, business

الوصف: Made available in DSpace on 2020-12-10T19:44:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01 This article describes the use of Photodynamic Therapy (PDT) during the endodontic treatment of teeth with periapical lesion. Patients presented tooth 35 with diagnostic hypotheses of Periapical Cyst or Granuloma. The Crown-Down preparation was performed with the HyFlex CM system. In case I it was not possible to reach the working length, in case II the foraminal debridement was performed at the actual tooth length. In the final irrigation, the E1 - Irrisonic ultrasonic insert was used, promoting sequentially agitation of NaOCl 2.5%, EDTA 17% and NaOCl 2.5%. Then, PDT was applied with 0.005% methylene blue dye. Calcium Hydroxide with Parammonochlorophenol was used and after 15 days, the final irrigation protocol and PDT were performed again. After 90 days of case I and 1 year of case II, the total lesion regression was observed in both cases. It is concluded that the proposed treatment improved the microbial disinfection favoring the regression of the periapical alterations providing satisfactory clinical and radiographic results. Univ Estadual Paulista, Fac Dent Araraquara, Dept Restorat Dent, Araraquara, SP, Brazil Univ Fed Alfenas, Dept Clin & Surg, Alfenas, MG, Brazil Univ Estadual Paulista, Fac Dent Araraquara, Dept Restorat Dent, Araraquara, SP, Brazil

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773883f91f0c182033bad3e0d6344a19Test
https://doi.org/10.1016/j.pdpdt.2019.09.002Test

المؤلفون: Sungtae Kim, Jung-Ju Kim, Ki-Tae Koo, Yang-Jo Seol, Yong-Moo Lee, Jung-Chul Park, Tae Il Kim, Heithem Ben Amara, In-Chul Rhyu, Young Ku

المصدر: Journal of Periodontology. 90:416-424

مصطلحات موضوعية: 0301 basic medicine, Bone Regeneration, Bone Morphogenetic Protein 2, Dentistry, Beagle, Lesion, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Transforming Growth Factor beta, Hyaluronic acid, medicine, Animals, Humans, Hyaluronic Acid, Dental alveolus, biology, business.industry, X-Ray Microtomography, 030206 dentistry, Recombinant Proteins, Periapical lesion, 030104 developmental biology, chemistry, Collagen sponge, Osteocalcin, biology.protein, Periodontics, medicine.symptom, Wound healing, business

الوصف: Background This experimental study aims to evaluate the effect of hyaluronic acid on healing of infected extraction sockets compared with recombinant human bone morphogenetic protein-2 (rhBMP-2). Methods Both third and fourth mandibular premolars of six beagle dogs were hemisected, and the distal roots were extracted at baseline. Subsequently, combined endodontic-periodontic lesions were induced at the remaining mesial roots. After 4 months, the mesial roots on both sides of the mandible were removed. Four sockets per dog were randomly allocated to four groups: Group 1, Control; Group 2, only absorbable collagen sponge (ACS: carrier); Group 3, 1% hyaluronic acid (HA) gel + ACS; and Group 4, rhBMP-2 + ACS. After 3 months of healing, the dogs were euthanized for microcomputed tomography and histologic analysis. Results After the lesion induction period (4 months), communication between the periodontal lesion and endodontic periapical lesion was observed at all remaining mesial roots. Alveolar bone overgrowth was observed in groups 3 and 4, but bone volume density was not significantly different among all groups. At the crestal portion, mineralization, and osteocalcin expression were higher in groups 3 and 4 than in groups 1 and 2. Conclusion Treatment with HA can promote bone formation and improve the wound healing rate comparable to rhBMP-2 in infected extraction sockets.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbee0a173038f38b7435b5b7d13036b4Test
https://doi.org/10.1002/jper.18-0348Test

المؤلفون: Juan J. Segura-Egea, C. B. M. Cardoso, Francine Benetti, Leticia Citelli Conti, Phc Oliveira, Suely Regina Mogami Bomfim, Mariane Maffei Azuma, Luciano Tavares Angelo Cintra

المساهمون: Universidade Estadual Paulista (Unesp), University of Sevilla, Universidade Federal de Minas Gerais (UFMG), University of Michigan

المصدر: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

مصطلحات موضوعية: Vitamin, Male, medicine.medical_specialty, medicine.medical_treatment, 0206 medical engineering, 02 engineering and technology, systemic disorders, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Animals, Humans, Rats, Wistar, Ligature, General Dentistry, Dental alveolus, Periodontitis, Inflammation, medicine.diagnostic_test, Triglyceride, business.industry, 030206 dentistry, apical periodontitis, medicine.disease, Atherosclerosis, 020601 biomedical engineering, Lipids, endodontic medicine, Rats, Periapical lesion, Endocrinology, chemistry, Pulp (tooth), atherosclerosis, Lipid profile, business, Periapical Periodontitis

الوصف: Made available in DSpace on 2020-12-12T02:15:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Aim: To investigate the relationship between apical periodontitis and atherosclerosis in rats by lipid profile and carotid artery intima tunic measurement, and histological and histometric evaluation of periapical lesions. Methodology: Forty male Wistar rats were allocated into four groups: control (C), with apical periodontitis (AP), with atherosclerosis (AT) and with AP and AT (AP + AT). Atherosclerosis was induced using a high-lipid diet associated with a surgical ligature in the carotid artery and a super dosage of vitamin D3. AP was induced via pulp exposure to the oral environment. At 45 and 75 days, serum levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were measured. The maxillary and mandibular jaws and carotid artery were collected and processed for histological analysis. The Kruskal–Wallis or Mann–Whitney test was performed for nonparametric data, and the Tukey’s or Student’s t-test was performed for parametric data (P ' 0.05). Results: In nonatherosclerotic animals, the induction of apical periodontitis increased TG levels significantly, from 63.1 ± 11.4 mg dL−1 in group C to 88.2 ± 7.9 mg dL−1 in the AP group (P ' 0.05). The induction of AP was associated with a trend for higher TC and LDL-C levels in atherosclerotic animals (P ' 0.05); however, it only significantly increased TG levels, from 93.2 ± 18.0 mg dL−1 in AT group to 121.9 ± 14.5 mg dL−1 in the AP + AT group (P ' 0.05). Animals in the AP + AT group had a 36.5% increase in the thickness of the carotid intima tunic when compared with the AT group (P ' 0.05). The intensity of the inflammatory infiltrate was significantly larger in the AP + AT group when compared with AP group (P ' 0.05). The AP + AT group exhibited significantly greater alveolar bone loss, with a periapical lesion size of 206.4 ± 56.3 × 104 μm2, compared with 151.4 ± 49.1 × 104 μm2 in the AP group (P ' 0.05). Conclusion: Apical periodontitis influenced triglyceride levels, increasing them even in the absence of atherosclerosis, and influenced the increase in the thickness of the carotid artery intima tunic in the presence of atherosclerosis. Atherosclerosis intensified the inflammatory reaction and increased bone resorption in periapical lesions. Endodontic Section Department of Preventive and Restorative Dentistry School of Dentistry São Paulo State University (Unesp) Endodontic Section Department of Stomatology School of Dentistry University of Sevilla Endodontic Section Department of Restorative Dentistry School of Dentistry Federal University of Minas Gerais Department of Cariology Restorative Sciences and Endodontics University of Michigan Department Clinic and Surgery and Animal Reproduction Araçatuba Veterinary Medicine São Paulo State University (Unesp) Endodontic Section Department of Preventive and Restorative Dentistry School of Dentistry São Paulo State University (Unesp) Department Clinic and Surgery and Animal Reproduction Araçatuba Veterinary Medicine São Paulo State University (Unesp) FAPESP: 2016/08005-0 CNPq: 311650/2018-0 CNPq: 436122/2018-9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4826b3b72a5385584d37650f1ec1fc87Test