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المؤلفون: E. G. Knysh, O. I. Panasenko, I. I. Aksyonova-Seliuk
المصدر: Фармацевтичний журнал, Vol 6, Pp 60-65 (2018)
مصطلحات موضوعية: Tert butyl, Chemical structure, lcsh:RM1-950, 1,2,4-Triazole, lcsh:RS1-441, Biological activity, Antimicrobial, Mass spectrometry, organic synthesis, High-performance liquid chromatography, lcsh:Pharmacy and materia medica, chemistry.chemical_compound, lcsh:Therapeutics. Pharmacology, chemistry, 5-(4-(tert-butyl)phenyl)-4-((R)amino)-4Н-1, 4-triazoles, Organic chemistry, Organic synthesis, 4-triazole-3-thiols
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e53efe5c0264ba1fdb2e64a1084837fTest
https://pharmj.org.ua/index.php/journal/article/view/101/69Test -
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المؤلفون: Yan Guo, Wenxue Fan, Yuefeng Xie, Shuyu Cao, Haitong Wan, Bo Jin
المصدر: Frontiers in Pharmacology, Vol 11 (2020)
مصطلحات موضوعية: 0301 basic medicine, Senescence, senescence, human umbilical vein cells, hydrogen peroxide, Umbilical vein, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, SIRT1, Pharmacology (medical), Hydrogen peroxide, Pharmacology, biology, Sirtuin 1, lcsh:RM1-950, Cell biology, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, chemistry, Apoptosis, 030220 oncology & carcinogenesis, 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside, biology.protein, 2 3 5 4 tetrahydroxystilbene 2 o β d glucoside, Target gene, Plasminogen activator
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca90bbcc021f24b82cbb7915e5b1af8Test
https://www.frontiersin.org/article/10.3389/fphar.2020.542902/fullTest -
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المؤلفون: Xian Wu, Liuyi Dong, Chuanying Dai, Mingqi Hou, Jin Qian, Jiaqiang Sun
المصدر: Biomedicine & Pharmacotherapy, Vol 124, Iss, Pp 109923-(2020)
مصطلحات موضوعية: 0301 basic medicine, Polygonum, RM1-950, 03 medical and health sciences, 0302 clinical medicine, Traditional Chinese medicine, Glucosides, Polygonummultiflorum, Stilbenes, Animals, Humans, Medicine, Chinese Traditional, Pharmacology, biology, Traditional medicine, Chemistry, General Medicine, biology.organism_classification, Tetrahydroxystilbene, Pharmacological action, Extraction Purification, 030104 developmental biology, Pharmacological activities, 030220 oncology & carcinogenesis, Fallopia multiflora, Therapeutics. Pharmacology, 2 3 5 4 tetrahydroxystilbene 2 o β d glucoside
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caf9136677301121adaef56b3877808Test
http://www.sciencedirect.com/science/article/pii/S075333222030113XTest -
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المؤلفون: Hui-Hsia Hsieh, Yu-Hui Ni, Tien-Yuan Wu
المصدر: Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO4-8
مصطلحات موضوعية: Cellular metabolism, Chemistry, Applied Mathematics, General Mathematics, Related gene, 2 3 5 4 tetrahydroxystilbene 2 o β d glucoside, Molecular biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::839389ab93e65601c8d3c9ffd68dcf7fTest
https://doi.org/10.1254/jpssuppl.wcp2018.0_po4-8-43Test -
5دورية أكاديمية
المؤلفون: Sahin, Onur
المساهمون: Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji/Genel Biyoloji Bölümü., orcid:0000-0003-4944-0181, orcid:0000-0002-0483-9642, orcid:0000-0002-7687-3284, orcid:0000-0002-3595-6286, Inci, Duygu, Aydin, Rahmiye, Vatan, Ozgür, Cinkılıc, Nilüfer, G-2201-2019, O-7508-2015, AAH-5296-2021, AAH-8936-2021, 55082306300, 56261495600, 16235098100, 26533892300
مصطلحات موضوعية: Chemistry, Bovine serum-albumin, Double-strand dna, Copper(II) complex, In-vitro, Substituted 1,10-phenanthrolines, Platinum(II) complexes, Crystal-structure, Bsa binding, Derivaties, Phenanthroline, multidisciplinary, Complex, Viscometry, Schiff Bases, 1,10 phenanthroline, 4 [5 (4 methyl 1 piperazinyl)[2,5' bi 1h benzimidazol] 2' yl]phenol, Amino acid, Bovine serum albumin, Carboplatin, Cisplatin, Dna, Ethidium bromide, Glycine, Hydrogen, Hydroxyurea, Ligand, Oxaliplatin, Palladium complex, Transplatin
العلاقة: 2211-C; Makale - Uluslararası Hakemli Dergi; (OUAP (F)-2015/14); New Journal of Chemistry; Yurt içi; Sanayi; Inci, D. vd. (2019). ''Water-soluble binary and ternary palladium(II) complexes containing amino acids and intercalating ligands: Synthesis, characterization, biomolecular interactions and cytotoxicities''. New Journal of Chemistry, 43(12), 4681-4697.; https://doi.org/10.1039/c8nj05934aTest; https://hdl.handle.net/11452/39613Test; 000462541900003; 2-s2.0-85063220833; 4681; 4697; 43; 12
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المؤلفون: Gemma Navarro, Abdelouahid Samadi, Jordi Mestres, José Marco-Contelles, Mohammad A. Khasawneh, Rafael Franco, Irene Reyes-Resina, Haythem A. Saadeh
المصدر: Dipòsit Digital de la UB
Universidad de Barcelona
ACS Omega, Vol 3, Iss 12, Pp 17368-17375 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Dopaminergic transmission, Functional selectivity, General Chemical Engineering, High selectivity, G-protein-coupled receptors, 5-((4-Arylpiperazin-1-yl)methyl)quinolin-8-ols, Proteïnes G, Biased agonism, lcsh:Chemistry, Synthesis, Dopamine receptor D3, N-Arylpiperazines, Receptor, Chemistry, Malalties neurodegeneratives, Neurodegenerative Diseases, 5-((4-(Pyrimidin-2-yl)piperazin-1-yl)methyl)quinolin-8-ol, General Chemistry, lcsh:QD1-999, Dopamine receptor, Identification (biology), G Proteins, Signal transduction, Selectivity, Neuroscience
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc64c0088f5af2f27933f37dc1d508fTest
http://hdl.handle.net/10261/178192Test -
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المؤلفون: Samuel Meignan, Abigaëlle Gros, Tiphaine Rogez-Florent, Amélie Lansiaux, Catherine Foulon, Jean François Goossens, Raphaël Frédérick, Sebastien Gluszok, Bernard Masereel, Laurence Goossens, Perrine Six, Claudiu T. Supuran, Christine Bal-Mahieu, Andrea Scozzafava, Patrick Depreux
المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute, Groupe de Recherche Interdiscipinaire Innovation et Optimisation Thérapeutique - EA 4481 (GRIIOT), Université de Lille, Droit et Santé, Institut pour la Recherche sur le Cancer de Lille (U837 INSERM - IRCL), Institut pour la recherche sur le cancer de Lille [Lille] (IRCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche Jean-Pierre AUBERT - Neurosciences et Cancer -JPArc [Lille], Institut de Chimie Pharmaceutique Albert Lespagnol (ICPAL), Laboratorio di Chimica Bioinorganica (LCBI), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Laboratorio di Chimica Bioinorganica, Université de Namur [Namur] (UNamur), EA 4481 Groupe de Recherche Interdiscipinaire (GRIIOT), Faculté des Sciences Pharmaceutiques et Biologiques, Università degli Studi di Firenze = University of Florence [Firenze], Université de Namur [Namur], Plasticité Cellulaire et Cancer (CPAC) - U908 (CPAC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Catholique de Louvain (UCL), Génétique moléculaire et approches thérapeutiques des hémopathies malignes, IRCL-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Bioorganic & Medicinal Chemistry
Bioorganic & Medicinal Chemistry : the tetrahedron journal for research at the interface of chemistry and biology, Vol. 21, no. 6, p. 1451-1464 (2013)
Bioorganic & Medicinal Chemistry; Vol 21
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2013, 21 (6), pp.1451-1464. ⟨10.1016/j.bmc.2012.10.029⟩مصطلحات موضوعية: 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (4 bromophenyl) 1h pyrazole, Carbonate dehydratase ix inhibitor, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (2 phenantryl) 1h pyrazole, Unclassified drug, Clinical Biochemistry, Cell, Pharmaceutical Science, Drug structure, Antiproliferative activity, 1 (3 aminosulfonylphenyl) 3 hydroxymethyl 5 phenyl 1h pyrazole, 01 natural sciences, Biochemistry, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (4 methoxyphenyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 4 hydroxymethyl 5 (2 naphthyl) 1h pyrazole, Breast cancer, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (5 bromo 6 methoxynaphtalen 2 yl) 1h pyrazole, Catalytic Domain, Drug Discovery, Cytotoxicity, Hypoxia, Carbonic Anhydrase Inhibitors, ComputingMilieux_MISCELLANEOUS, Enzyme active site, Carbonic Anhydrases, chemistry.chemical_classification, 0303 health sciences, Sulfonamides, Carbonic anhydrase, biology, Chemistry, Aryl sulfonamide inhibitors, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (2 methoxyphenyl) 1h pyrazole, Carbonate dehydratase IX, 3. Good health, 1 (3 aminosulfonylphenyl) 3 hydroxymethyl 5 (6 methoxy 2 naphthalenyl) 1h pyrazole, Molecular Docking Simulation, Enzyme inhibition, medicine.anatomical_structure, Drug screening, Drug selectivity, Molecular Medicine, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (6 methoxynaphtalen 2 yl) 1h pyrazole, Simulation, medicine.drug, 1 (4 aminosulfonylphenyl) 5 hydroxymethyl 3 phenyl 1h pyrazole, Protein Binding, 1 (3 aminosulfonylphenyl) 3 hydroxymethyl 5 naphthyl 1h pyrazole, Drug cytotoxicity, 1 (4 aminosulfonylphenyl) 5 hydroxymethyl 3 (2 naphthyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 pyridinyl 1h pyrazole, Drug binding, Sulfonamide, Article, Molecular model, 03 medical and health sciences, Drug synthesis, Structure-Activity Relationship, Drug potency, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Antigens, Neoplasm, Cell Line, Tumor, medicine, Humans, Doxorubicin, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (1 naphthyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 4 hydroxymethyl 5 phenyl 1h pyrazole, Carbonic Anhydrase IX, Molecular Biology, 1 (4 aminosulfonylphenyl) 3 hydroxyethyl 5 phenyl 1h pyrazole, 030304 developmental biology, Cell Proliferation, 1 (4 aminosulfonylphenyl) 4 hydroxymethyl 5 (6 methoxy 2 naphtalenyl) 1h pyrazole, Carbonate dehydratase inhibitor, Cell strain MDA MB 231, Binding Sites, 010405 organic chemistry, Organic Chemistry, Active site, In vitro, 0104 chemical sciences, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (2 naphthyl) 1h pyrazole, Kinetics, Enzyme, Binding kinetics, Tumor progression, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (4 tolyl) 1h pyrazole, Pyrazole, biology.protein, Pyrazoles, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (3 methoxyphenyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 phenyl 1h pyrazole, Cell line, 4 (5 aryl 2 hydroxymethyl pyrazol 1 yl)benzenesulfonamide
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24fc0ffbfbf6b174096e2e6e1a78a94Test
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المؤلفون: F. Ivy Carroll, Abhijit R. Kulkarni, Ganesh A. Thakur, Deniz Bagdas, Shakir D. AlSharari, Giulia Donvito, M. Imad Damaj, Julie A. Meade, Elnaz Rahimpour, Aron H. Lichtman, Roger L. Papke, Wisam Toma, Asti Jackson
المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Deney Hayvanları Yetiştirme ve Araştırma Merkezi., Bağdaş, Deniz
مصطلحات موضوعية: Target, Male, Nociception, Mouse, Inflammatory pain, medicine.medical_treatment, Pharmacology, Signal transduction, Antagonists and inhibitors, Cannabinoid receptor antagonists, Antinociception, Mice, 0302 clinical medicine, Models, Peroxisome proliferator activated receptor antagonist, Nicotinic Antagonist, Oxazoles, Azabicyclo derivative, Pain measurement, GW 6471, Analogs and derivatives, Neurology, Ethanolamines, Mechanism, Cholinergic receptor stimulating agent, Agonist, medicine.medical_specialty, Tonic pain, Alpha7 nicotinic acetylcholine receptor, Article, 03 medical and health sciences, Palmitic acid derivative, Cannabinoid receptor antagonist, Bridged bicyclo compounds, PPAR alpha, Palmidrol, Animal model, Positive allosteric modulator, Animal experiment, Palmitoylethanolamide, Nociceptive pain, 5 (4 chloro 3 methylphenyl) 1 (4 methylbenzyl) n (1,3,3 trimethylbicyclo[2.2.1]heptan 2 yl) 3 pyrazolecarboxamide, Animal, Inflammation, Methyllycaconitine, 3-(2,4-Dimethoxybenzylidene)Anabaseine, Amides, Institute for cancer research mouse, Pnu-120596, 030104 developmental biology, Endocrinology, chemistry, Peroxisome proliferator activated receptor alpha, 030217 neurology & neurosurgery, 0301 basic medicine, Cannabinoid 2 receptor, Nicotinic acetylcholine receptors, Unclassified drug, Neuropathic pain, Gat107, Azabicyclo compounds, Nicotinic antagonists, Oleoylethanolamide, chemistry.chemical_compound, Bungarotoxin receptor, 1 (5 chloro 2,4 dimethoxyphenyl) 3 (5 methyl 3 isoxazolyl)urea, Priority journal, Benzamide derivative, Palmitic acids, Pamgat 107, Ethanolamine derivative, Nicotinic acetylcholine receptor, Nicotinic agonist, Mice, inbred ICR, Benzamides, G-proteins, Rimonabant, 1,4-diazabicyclo(3.2.2)nonan-4-yl(5-(3-(trifluoromethyl)phenyl)furan-2-yl)methanone, Furan derivative, medicine.drug_class, Nuclear peroxisome proliferator-activated receptor type-α, Neurosciences & neurology, PNU-282987, Nicotinic receptor blocking agent, Developmental Neuroscience, Internal medicine, medicine, Animals, Furans, Drug effects, Neurosciences, Alpha7, Oxazole derivative, Cannabinoid 1 receptor, Nonhuman, Receptor cross-talk, Protein protein interaction, Tyrosine, NS 6740, Cannabinoid, Cell nucleus, Controlled study, 4 chloro n (3 quinuclidinyl)benzamide
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ea9d727a8e43b74cb10445104dd912Test
http://hdl.handle.net/11452/29379Test -
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المؤلفون: Ceyda Icsel, Veysel T. Yilmaz
المساهمون: Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü., İçsel, Ceyda, Yılmaz, Veysel Turan, AAI-3342-2021, L-7238-2018
المصدر: Journal of Photochemistry and Photobiology B: Biology. 130:115-121
مصطلحات موضوعية: Platinum(II) complexes, Male, Biochemistry & molecular biology, Palladium(II), Coordination complexes, Intercalation (chemistry), chemistry.chemical_compound, Saccharin, Crystal, Ultraviolet spectroscopy, Intercalation, DNA denaturation, Fluorometry, Fluorescence spectroscopy, Cancer, Priority journal, Zinc(II) saccharinate, Gel electrophoresis, DNA cleavage, Radiation, Radiological and Ultrasound Technology, Viscosity, 4 [5 (4 methyl 1 piperazinyl)[2,5' bi 1h benzimidazol] 2' yl]phenol, copper complex, Titrimetry, Metal-complexes, Zinc, Copper(II) saccharinate, visual_art, visual_art.visual_art_medium, Titration, Zinc complex, Ethidium bromide, Viscometry, Inorganic chemistry, Biophysics, chemistry.chemical_element, Inutero-exposure, Static electricity, Article, Absorption, Metal, Conformational transition, DNA helix, Radiology, Nuclear Medicine and imaging, DNA binding, Hydrogen bond, In vitro study, DNA, UV-Vis spectroscopy, Complex, Palladium, 2-Phenylpyridine, Nonhuman, Copper, Recognition, Binding affinity, chemistry, Acridine-orange, Sweetening agents, Ethidium-bromide, Nuclear chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554ec986af430ee0307c87e5c887d4caTest
https://doi.org/10.1016/j.jphotobiol.2013.11.001Test -
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المؤلفون: Mukeshd Doble, Ponnurengam Malliappan Sivakumar
المصدر: Medicinal Chemistry. 4:110-115
مصطلحات موضوعية: Models, Molecular, Steric effects, Quantitative structure–activity relationship, Binding Sites, Cyclooxygenase 2 Inhibitors, biology, Chemistry, Stereochemistry, Hydrogen bond, Binding energy, Quantitative Structure-Activity Relationship, Active site, Hydrogen Bonding, Interaction energy, 1 (4 fluorophenyl) 2 [(4 methylsulfonyl)phenyl]cyclopentene, 4 [5 (4 bromophenyl) 3 trifluoromethyl 1h pyrazol 1 yl]benzenesulfonamide, 5 (4 fluorophenyl) 1 [(4 methylsulfonyl)phenyl] 3 trifluoromethylpyrazole, 5 bromo 2 (4 fluorophenyl) 3 (4 methylsulfonylphenyl)thiophene, celecoxib, cyclooxygenase 2, cyclooxygenase 2 inhibitor, l 768 277, n (2 cyclohexyloxy 4 nitrophenyl)methanesulfonamide, nimesulide, prostaglandin synthase inhibitor, rofecoxib, sc 58451, valdecoxib, binding affinity, binding site, blood brain barrier, computer model, computer prediction, drug penetration, drug protein binding, drug structure, enzyme activity, IC 50, mathematical computing, priority journal, quantitative analysis, structure activity relation, chemical structure, chemistry, human, hydrogen bond, protein binding, quantitative structure activity relation, solubility, Blood-Brain Barrier, Cyclooxygenase 2, Humans, Inhibitory Concentration 50, Protein Binding, Solubility, Drug Discovery, biology.protein, Molecule, HOMO/LUMO
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee361189381f7e3d39df02cbddbe431bTest
https://doi.org/10.2174/157340608783789112Test