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1
المؤلفون: Tony Tiganis, Pei Kee Goh, Chrysovalantou E. Xirouchaki, Spencer Greatorex, Kevin Sek, Paul A. Beavis, Rachel Xu, Xin Du, Samuel J. Hogarth, Phillip K. Darcy, Mara N. Zeissig, Kun-Hui Lu, Roger J. Daly, Florian Wiede, Nicholas K. Tonks
المصدر: Cancer Discov
مصطلحات موضوعية: T cell, Programmed Cell Death 1 Receptor, Cell, Cell- and Tissue-Based Therapy, CD8-Positive T-Lymphocytes, Immunotherapy, Adoptive, Article, Mice, Downregulation and upregulation, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Cytotoxicity, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Chemistry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Blockade, medicine.anatomical_structure, Oncology, Cancer research, hormones, hormone substitutes, and hormone antagonists, CD8, Intracellular
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe8179c7b63b6bcc3c67dfaef438480Test
https://doi.org/10.1158/2159-8290.cd-21-0694Test -
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المؤلفون: Su-Xia Sun, Hao Zhang, Xian-Chao Cheng, Zhihui Zheng, Ting-Ting Ding, Run-Ling Wang, Li-Song Zhang, Yang-Chun Ma, Xin-Hua Lu, Ya-Ya Liu
المصدر: Biochemical and Biophysical Research Communications. 579:40-46
مصطلحات موضوعية: Chemistry, Pharmaceutical, Drug Evaluation, Preclinical, Biophysics, Molecular Dynamics Simulation, Imidazolidines, Inhibitory postsynaptic potential, Biochemistry, Inhibitory Concentration 50, chemistry.chemical_compound, Molecular dynamics, Imidazolidine, Catalytic Domain, Humans, Enzyme Inhibitors, Molecular Biology, Biological evaluation, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Cell Biology, Small molecule, Molecular Docking Simulation, chemistry, Design synthesis, Drug Design, Signal transduction, Selectivity, Algorithms, Software, hormones, hormone substitutes, and hormone antagonists, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97757944edc0809c4fca6952ec3ed3a7Test
https://doi.org/10.1016/j.bbrc.2021.09.047Test -
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المؤلفون: Jae Sue Choi, Seo Young Yang, Vu Thi Oanh, Byung Sun Min, Nguyen Viet Phong, Jeong Ah Kim
المصدر: International Journal of Biological Macromolecules. 188:719-728
مصطلحات موضوعية: Dryopteris, Dryopteris crassirhizoma, Stereochemistry, Proton Magnetic Resonance Spectroscopy, In silico, Phloroglucinol, Biochemistry, Molecular Docking Simulation, chemistry.chemical_compound, Ursolic acid, Structural Biology, Catalytic Domain, Carbon-13 Magnetic Resonance Spectroscopy, Molecular Biology, Sodium orthovanadate, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, biology, General Medicine, biology.organism_classification, In vitro, Kinetics, Enzyme, chemistry, Two-dimensional nuclear magnetic resonance spectroscopy, Rhizome
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1850c0fa41517dde1ff7166d9caf78Test
https://doi.org/10.1016/j.ijbiomac.2021.08.091Test -
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المؤلفون: Lei Zhang, Yang Ying, Zhiyan Xiao, Fei Ye, Jin-Ying Tian
المصدر: Journal of Chemical Information and Modeling. 61:4720-4732
مصطلحات موضوعية: Protein Tyrosine Phosphatase, Non-Receptor Type 1, Virtual screening, Drug discovery, Chemistry, General Chemical Engineering, Allosteric regulation, Structural diversity, General Chemistry, Computational biology, Protein tyrosine phosphatase, Molecular Dynamics Simulation, Library and Information Sciences, Integrated approach, Protein Tyrosine Phosphatase 1B, Computer Science Applications, Catalytic Domain, Enzyme Inhibitors, Allosteric Site, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb000e0313c2b7fb068943b722409658Test
https://doi.org/10.1021/acs.jcim.1c00357Test -
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المؤلفون: Chuan-Yuan Wei, Xin-Yi Deng, Qiang Wang, Yanwen Yang, Leqi Qian, Fazhi Qi, Jiaqi Liu, Lu Wang
المصدر: Experimental Dermatology. 31:202-213
مصطلحات موضوعية: Protein Tyrosine Phosphatase, Non-Receptor Type 1, MAPK/ERK pathway, Gene knockdown, Cell growth, Chemistry, Motility, Dermatology, Protein tyrosine phosphatase, Fibroblasts, medicine.disease, Biochemistry, Hedgehog signaling pathway, Extracellular Matrix, Cell biology, Extracellular matrix, Keloid, medicine, Humans, skin and connective tissue diseases, Molecular Biology, Cells, Cultured, hormones, hormone substitutes, and hormone antagonists, Cell Proliferation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1a83c0ae81d16f7f69af6e41fd2777Test
https://doi.org/10.1111/exd.14443Test -
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المؤلفون: Bikash Medhi, Phulen Sarma, Ajay Prakash, Seema Bansal, Rupa Joshi, Nitika Garg, Kanwaljit Chopra, Subodh Kumar, Saniya Mahendiratta, Amit Sharma, Madhunika Agrawal
المصدر: Brain Research Bulletin. 171:113-125
مصطلحات موضوعية: Male, 0301 basic medicine, Morris water navigation task, Pharmacology, Hippocampus, Diabetes Mellitus, Experimental, Wortmannin, 03 medical and health sciences, chemistry.chemical_compound, Cognition, 0302 clinical medicine, Insulin resistance, Neurotrophic factors, Avoidance Learning, Animals, Medicine, Rats, Wistar, Cognitive decline, Maze Learning, Neuroinflammation, Cerebral Cortex, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Alendronate, biology, business.industry, Akt/PKB signaling pathway, General Neuroscience, medicine.disease, Rats, Oxidative Stress, Insulin receptor, 030104 developmental biology, chemistry, biology.protein, Insulin Resistance, business, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b0721daab8e1bbff7f5763b35fb751Test
https://doi.org/10.1016/j.brainresbull.2021.02.026Test -
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المؤلفون: Nathan Long, Adam Le Gresley, Stephen P. Wren
المصدر: Chemmedchem
مصطلحات موضوعية: PPARγ, endocrine system diseases, Chemistry, Pharmaceutical, Pharmacology, chemistry, 01 natural sciences, Biochemistry, Aldehyde Reductase, Diabetes mellitus, Drug Discovery, Diabetes Mellitus, medicine, Animals, Humans, Hypoglycemic Agents, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Biological sciences, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Aldose reductase, ALR2, 010405 organic chemistry, Chemistry, Organic Chemistry, PTP1B, nutritional and metabolic diseases, Minireviews, medicine.disease, Protein Tyrosine Phosphatase 1B, 0104 chemical sciences, PPAR gamma, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Thiazolidinediones, Minireview, Pharmacophore, biological
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1414f8c86795d0a05cfedb80650f76b9Test
https://doi.org/10.1002/cmdc.202100177Test -
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المؤلفون: Xue Li, Minmin Zhu, Ting Huang, Changhong Miao, Fei Wang, Wenting Hou, Lihong Lu
المصدر: Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Cell Death & Diseaseمصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_specialty, Endothelium, Immunology, CREB, Article, Umbilical vein, Histone H4, Diabetic nephropathy, Pathogenesis, 03 medical and health sciences, Cellular and Molecular Neuroscience, Diabetes complications, Internal medicine, medicine, Animals, Humans, Diabetic Nephropathies, lcsh:QH573-671, Cyclic AMP Response Element-Binding Protein, Protein Tyrosine Phosphatase, Non-Receptor Type 1, 030102 biochemistry & molecular biology, biology, Chemistry, lcsh:Cytology, Type 2 diabetes, Cell Biology, Methylation, Middle Aged, medicine.disease, Rats, Glucose, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Hyperglycemia, biology.protein, Phosphorylation, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c159e8de27353c026b316e2d39021bbfTest
https://doaj.org/article/4abb9c8e7d2b4e1fba4ee9466da74fa8Test -
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المؤلفون: Wenli Hu, Zhenou Sun, Chong Zhao, Shangyun Lu, Hongbo Hu, Shutao Yin
المصدر: Cancer Science
مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, MAP Kinase Signaling System, medicine.medical_treatment, tumor‐intrinsic signal, B7-H1 Antigen, 03 medical and health sciences, Interferon-gamma, Mice, 0302 clinical medicine, Mediator, Cell, Molecular, and Stem Cell Biology, In vivo, Cell Movement, PD-L1, Cell Line, Tumor, medicine, melanoma, Animals, Humans, Phosphorylation, Cell Proliferation, Protein Tyrosine Phosphatase, Non-Receptor Type 1, biology, Cell growth, Kinase, Chemistry, Cancer, General Medicine, Immunotherapy, Original Articles, Proto-Oncogene Proteins c-met, medicine.disease, Mice, Inbred C57BL, lung cancer, 030104 developmental biology, Oncology, PD‐L1, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Disease Progression, Heterografts, Original Article, RNA Interference, MET phosphorylation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e904c7d978189daa580b44d637cedcaeTest
http://europepmc.org/articles/PMC8088939Test -
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المؤلفون: Akarawin Hongdusit, Jerome M. Fox
المصدر: Biochemistry. 60:254-258
مصطلحات موضوعية: Protein Tyrosine Phosphatase, Non-Receptor Type 1, Protein Tyrosine Phosphatase, Non-Receptor Type 2, 0303 health sciences, Chemistry, Light switch, 030302 biochemistry & molecular biology, Allosteric regulation, Protein domain, Protein tyrosine phosphatase, Optogenetics, Biochemistry, Protein Tyrosine Phosphatase 1B, Fusion gene, 03 medical and health sciences, Allosteric Regulation, Helix, Biophysics, Humans
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2875b51ff7472191b6bcf55c44de4b3fTest
https://doi.org/10.1021/acs.biochem.0c00841Test