نتائج البحث - "Kenneth P Nephew"

1

Targeting Ovarian Cancer Stem Cells by Dual Inhibition of HOTAIR and DNA Methylation

المؤلفون: Ali R. Özeş, Fang Fang, Weini Wang, Kenneth P. Nephew

المصدر: Mol Cancer Ther

مصطلحات موضوعية: Peptide Nucleic Acids, 0301 basic medicine, Cancer Research, Cell, Population, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, DNA (Cytosine-5-)-Methyltransferases, education, Cell Proliferation, Ovarian Neoplasms, education.field_of_study, Chemistry, EZH2, HOTAIR, DNA Methylation, medicine.disease, Xenograft Model Antitumor Assays, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Oncology, Cell culture, 030220 oncology & carcinogenesis, DNA methylation, Azacitidine, Neoplastic Stem Cells, Cancer research, Female, RNA, Long Noncoding, Stem cell, Ovarian cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0720d8dbd6ab3f6fd51ff5aed05d8ccTest
https://doi.org/10.1158/1535-7163.mct-20-0826Test

2

A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer

المساهمون: Blagden, Sarah P [0000-0001-8783-3491], Markham, Merry Jennifer [0000-0003-3567-3494], Hirte, Hal W [0000-0003-2888-4146], Hall, Geoff D [0000-0002-8864-5932], Apollo - University of Cambridge Repository

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Paclitaxel, medicine.medical_treatment, Neutropenia, Deoxycytidine, Gastroenterology, Article, Carboplatin, Epigenesis, Genetic, Polyethylene Glycols, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Clinical endpoint, Humans, Medicine, Survival rate, Aged, Aged, 80 and over, Ovarian Neoplasms, Chemotherapy, business.industry, Middle Aged, medicine.disease, Gemcitabine, Survival Rate, Treatment Outcome, 030104 developmental biology, Oncology, chemistry, Doxorubicin, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Azacitidine, Female, Topotecan, Patient Safety, Neoplasm Recurrence, Local, business, Ovarian cancer, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0132937e4799a70c839d4097d50cabd8Test
https://doi.org/10.1158/1078-0432.ccr-19-1638Test

3

Profiling Cell–Matrix Adhesion Using Digitalized Acoustic Streaming

المؤلفون: Zhuhao Wu, Richard L. Carpenter, Zheng Ao, Hongwei Cai, Lei Jiang, Asael Nunez, Feng Guo, Kenneth P. Nephew

المصدر: Analytical Chemistry. 92:2283-2290

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6017b6b41b803135cf45a3a8a9a116cfTest
https://doi.org/10.1021/acs.analchem.9b05065Test

4

Combined epigenetic and metabolic inhibition blocks platinum-induced ovarian cancer stem cell enrichment

المؤلفون: Riddhi Sood, Shruthi Sriramkumar, Vaishnavi Muralikrishnan, Sikai Xiao, Weini Wang, Christiane Hassel, Kenneth P. Nephew, Heather M. O’Hagan

مصطلحات موضوعية: Methyltransferase, endocrine system diseases, biology, Chemistry, Aldehyde dehydrogenase, Promoter, medicine.disease, female genital diseases and pregnancy complications, DNA methylation, biology.protein, medicine, Cancer research, Epigenetics, NAD+ kinase, Stem cell, Ovarian cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3a81616bebba938563220f64e0c37b75Test
https://doi.org/10.1101/2021.03.18.435878Test

5

Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A is Mediated by Replication Protein A in Ovarian Cancer

المؤلفون: John J. Turchi, Timothy D. Matthews, Pamela S. VanderVere-Carozza, Katherine S. Pawelczak, Samuel A. Miller, Shruthi Sriramkumar, Ahmed H. Ghobashi, Kenneth P. Nephew, Heather M. O'Hagan

المصدر: Mol Cancer Res

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b29d58adecb033cd553f7339052fc6Test

6

Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion

المؤلفون: Harold N. Keer, Ning Ding, M. Sharon Stack, Jessica Tang, Nicholas Pulliam, Kenneth P. Nephew, Heather M. O'Hagan, Doug Rusch, Aaron Buechlein, Ali R. Özeş

المصدر: Molecular Cancer Research. 16:1226-1240

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cafa306ba9ab18447b8ccb3abef89a2Test
https://doi.org/10.1158/1541-7786.mcr-17-0406Test

7

An Effective Epigenetic-PARP Inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA Mutations

المؤلفون: Nicholas Pulliam, Harold N. Keer, John Lyons, Kenneth P. Nephew, Fang Fang, Feyruz V. Rassool, Stephen B. Baylin, Harikrishna Nakshatri, Kathy D. Miller, Daniela Matei, Jessica Tang, Ali R. Özeş, Adeoluwa Adewuyi

المصدر: Clinical Cancer Research. 24:3163-3175

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, Combination therapy, Poly(ADP-ribose) Polymerase Inhibitors, Article, Epigenesis, Genetic, Mice, 03 medical and health sciences, chemistry.chemical_compound, Breast cancer, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, Cyclic AMP, medicine, Animals, Humans, Talazoparib, skin and connective tissue diseases, BRCA2 Protein, Ovarian Neoplasms, BRCA1 Protein, business.industry, BRCA mutation, Cancer, medicine.disease, Cyclic AMP-Dependent Protein Kinases, Xenograft Model Antitumor Assays, female genital diseases and pregnancy complications, Disease Models, Animal, 030104 developmental biology, Oncology, chemistry, Tumor progression, Mutation, PARP inhibitor, Cancer research, Phthalazines, Female, Reactive Oxygen Species, Ovarian cancer, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79f4b6c42551aa85a53234ff0b86746Test
https://doi.org/10.1158/1078-0432.ccr-18-0204Test

8

Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)

مصطلحات موضوعية: Multidisciplinary, Science, General Physics and Astronomy, Sterol homeostasis, chemistry.chemical_element, General Chemistry, Biology, Non-coding RNA, Oxygen, General Biochemistry, Genetics and Molecular Biology, Cell biology, chemistry, lcsh:Q, lcsh:Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ed4294654232c0a2f7a9f4078106ffTest
http://link.springer.com/article/10.1038/s41467-020-19708-7Test

9

Abstract B63: Lysophosphatidic acid as a mediator of ovarian cancer cell stemness

المؤلفون: Kenneth P. Nephew, Yuliya Klymenko

المصدر: Clinical Cancer Research. 26:B63-B63

مصطلحات موضوعية: Cancer Research, education.field_of_study, business.industry, Population, Cell, Cancer, medicine.disease, Metastasis, chemistry.chemical_compound, medicine.anatomical_structure, Oncology, chemistry, Cancer stem cell, Lysophosphatidic acid, Cancer research, medicine, Stem cell, business, Ovarian cancer, education

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::984bfac0a3ec16916afa465d9f939052Test
https://doi.org/10.1158/1557-3265.ovca19-b63Test

10

Targeting Aldehyde Dehydrogenases to Eliminate Cancer Stem Cells in Gynecologic Malignancies

المؤلفون: Thomas D. Hurley, Kenneth P. Nephew, Vaishnavi Muralikrishnan

المصدر: Cancers
Cancers, Vol 12, Iss 961, p 961 (2020)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce482e7fd510d09c5a370a2efbb72ddaTest
https://doi.org/10.3390/cancers12040961Test

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