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المؤلفون: Niels Hellings, Jeroen F. J. Bogie, Bert O. Eijnde, Bieke Broux, Shahid P Baba, Dheeraj Kumar Posa, Charly Keytsman, Tim Vanmierlo, Laura Blancquaert, Wouter M. A. Franssen, David Hoetker, Jack van Horssen, Wim Derave, Jan H. Spaas
المساهمون: SPAAS, Jan/0000-0002-4953-2505, RS: MHeNs - R3 - Neuroscience, Psychiatrie & Neuropsychologie, Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation
المصدر: JOURNAL OF NEUROINFLAMMATION
Journal of Neuroinflammation, 18(1):255. BioMed Central Ltd
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-19 (2021)
Journal of Neuroinflammation, 18(1):255. BioMed Central
Spaas, J, Franssen, W M A, Keytsman, C, Blancquaert, L, Vanmierlo, T, Bogie, J, Broux, B, Hellings, N, van Horssen, J, Posa, D K, Hoetker, D, Baba, S P, Derave, W & Eijnde, B O 2021, ' Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation ', Journal of Neuroinflammation, vol. 18, no. 1, 255 . https://doi.org/10.1186/s12974-021-02306-9Test
Journal of Neuroinflammationمصطلحات موضوعية: Male, Acrolein, Carnosine, Multiple sclerosis, Neuroinflammation, Oxidative, Pharmacology, medicine.disease_cause, SUPPLEMENTATION, Mice, chemistry.chemical_compound, Reactive carbonyl, CHEMISTRY, Medicine and Health Sciences, PROTEIN CARBONYLATION, DAMAGE, Microglia, General Neuroscience, Experimental autoimmune encephalomyelitis, MULTIPLE-SCLEROSIS, medicine.anatomical_structure, Neurology, Female, medicine.symptom, Encephalomyelitis, Autoimmune, Experimental, Immunology, Inflammation, Nitric oxide, stress, Cellular and Molecular Neuroscience, Autoimmune Diseases of the Nervous System, medicine, Animals, Humans, TRANSCRIPTOME, RC346-429, DETOXIFICATION, Research, Biology and Life Sciences, HISTIDINE-CONTAINING DIPEPTIDES, medicine.disease, Mice, Inbred C57BL, chemistry, Oxidative stress, Neuroinflammatory Diseases, CELLS, Neurology. Diseases of the nervous system
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10493d5b0217197873f415df24e8fa39Test
http://www.scopus.com/inward/record.url?scp=85118759302&partnerID=8YFLogxKTest -
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المؤلفون: Maarten E. Witte, Tom Verhoeven, Jasper J. Koning, Jack van Horssen, Bert van het Hof, Lauri Borghuis, Merel Rijnsburger, Alwin Kamermans, Helga E. de Vries
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, ACS - Microcirculation
المصدر: Kamermans, A, Verhoeven, T, van het Hof, B, Koning, J J, Borghuis, L, Witte, M, van Horssen, J, de Vries, H E & Rijnsburger, M 2019, ' Setmelanotide, a Novel, Selective Melanocortin Receptor-4 Agonist Exerts Anti-inflammatory Actions in Astrocytes and Promotes an Anti-inflammatory Macrophage Phenotype ', Frontiers in Immunology, vol. 10, 2312 . https://doi.org/10.3389/fimmu.2019.02312Test
Frontiers in Immunology, 10:2312
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunologyمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Agonist, lcsh:Immunologic diseases. Allergy, medicine.drug_class, Immunology, Anti-Inflammatory Agents, macrophage, multiple sclerosis, Neuroprotection, 03 medical and health sciences, 0302 clinical medicine, astrocyte, Melanocortin receptor, medicine, Humans, Immunology and Allergy, melanocortin, Phosphorylation, Cyclic AMP Response Element-Binding Protein, Cells, Cultured, Original Research, Aged, melanocortin receptor-4, Interleukin-6, Chemistry, Macrophages, Neurodegeneration, Interleukin, Middle Aged, Interleukin-11, medicine.disease, Melanocortin 4 receptor, Phenotype, 030104 developmental biology, medicine.anatomical_structure, alpha-MSH, inflammation, Astrocytes, Cancer research, Receptor, Melanocortin, Type 4, Female, Melanocortin, lcsh:RC581-607, 030215 immunology, Astrocyte
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896b17f5ae96d8db4852179819d9bb35Test
https://research.vumc.nl/en/publications/ca4f60ca-aecc-435f-9bd3-00a1d1002c6aTest -
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المؤلفون: Elien Wouters, Dieter Lütjohann, Jerome J. A. Hendriks, Jeroen F. J. Bogie, Tim Vanmierlo, Jo Mailleux, Jack van Horssen
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation
المصدر: Multiple Sclerosis, 24(3), 279-289. SAGE Publications Ltd
Mailleux, J, Vanmierlo, T, Bogie, J F, Wouters, E, Lütjohann, D, Hendriks, J J & van Horssen, J 2018, ' Active liver X receptor signaling in phagocytes in multiple sclerosis lesions ', Multiple Sclerosis, vol. 24, no. 3, pp. 279-289 . https://doi.org/10.1177/1352458517696595Testمصطلحات موضوعية: 0301 basic medicine, Multiple Sclerosis, Phagocytosis, Tissue Banks, 03 medical and health sciences, Myelin, chemistry.chemical_compound, 0302 clinical medicine, polycyclic compounds, Humans, Medicine, Liver X receptor, Cells, Cultured, Myelin Sheath, Liver X Receptors, business.industry, Macrophages, Multiple sclerosis, Brain, demyelinating diseases, multiple sclerosis, myelin sheath, phagocytes, liver X receptor, 27-hydroxycholesterol, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Neurology, chemistry, Myelin sheath, Immunology, 27-Hydroxycholesterol, lipids (amino acids, peptides, and proteins), Neurology (clinical), business, 030217 neurology & neurosurgery, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3544204d18edeb350d531f5059a31bTest
https://doi.org/10.1177/1352458517696595Test -
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المؤلفون: Tim Vanmierlo, Sandra Amor, Suzan Wetzels, Kristiaan Wouters, Jerome J. A. Hendriks, Veerle Somers, Jean L.J.M. Scheijen, Casper G. Schalkwijk, Jack van Horssen
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Pathology, AII - Inflammatory diseases, RS: CARIM - R3 - Vascular biology, Interne Geneeskunde, MUMC+: MA Alg Onderzoek Interne Geneeskunde (9), RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, RS: MHeNs - R3 - Neuroscience, RS: Carim - B07 The vulnerable plaque: makers and markers, Pathologie, Psychiatrie & Neuropsychologie, RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome
المصدر: Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology, 10
Frontiers in Immunology, 10:855. Frontiers Media S.A.
Wetzels, S, Vanmierlo, T, Scheijen, J L J M, van Horssen, J, Amor, S, Somers, V, Schalkwijk, C G, Hendriks, J J A & Wouters, K 2019, ' Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions ', Frontiers in Immunology, vol. 10, pp. 855 . https://doi.org/10.3389/fimmu.2019.00855Testمصطلحات موضوعية: 0301 basic medicine, Glycation End Products, Advanced, Male, BIOMARKER, END-PRODUCTS AGES, multiple sclerosis, OXIDATION, DISEASE, RAGE (receptor), neuroinflammation, chemistry.chemical_compound, 0302 clinical medicine, Immunology and Allergy, Original Research, GENE-EXPRESSION, Microglia, Chemistry, Methylglyoxal, Middle Aged, Pyruvaldehyde, Immunohistochemistry, medicine.anatomical_structure, Disease Progression, Female, Disease Susceptibility, advanced glycation endproducts, lcsh:Immunologic diseases. Allergy, medicine.medical_specialty, alpha-dicarbonyl, astrocytes, Central nervous system, Immunology, MECHANISMS, 03 medical and health sciences, Immune system, CEREBROSPINAL-FLUID, Internal medicine, medicine, α-dicarbonyl, Humans, Neuroinflammation, Aged, Autoimmune disease, RECEPTOR, Multiple sclerosis, medicine.disease, INDIVIDUALS, 030104 developmental biology, Endocrinology, CHOROID-PLEXUS, lcsh:RC581-607, Biomarkers, 030215 immunology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bbb0a6c32d49bd865d71207d5160f7Test
https://cris.maastrichtuniversity.nl/en/publications/1a7ae3be-c424-419d-95d5-509a05bb113cTest -
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المؤلفون: Merel Rijnsburger, Ananya Chakraborty, Jack van Horssen, Susanne M. A. van der Pol, Alwin Kamermans, Helga E. de Vries
المساهمون: Molecular cell biology and Immunology, ACS - Microcirculation, Amsterdam Neuroscience - Neuroinfection & -inflammation
المصدر: Kamermans, A, Rijnsburger, M, Chakraborty, A, van der Pol, S, de Vries, H E & van Horssen, J 2019, ' Reduced angiopoietin-like 4 expression in multiple sclerosis lesions facilitates lipid uptake by phagocytes via modulation of lipoprotein-lipase activity ', Frontiers in Immunology, vol. 10, no. MAY, 950 . https://doi.org/10.3389/fimmu.2019.00950Test
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 10(MAY):950مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Adult, Male, Multiple Sclerosis, Phagocyte, Central nervous system, Immunology, Angiopoietin, 03 medical and health sciences, Myelin, 0302 clinical medicine, astrocyte, ANGPTL4, Cell Line, Tumor, medicine, Immunology and Allergy, Angiopoietin-Like Protein 4, Humans, Remyelination, Myelin Sheath, Aged, Original Research, Aged, 80 and over, Lipoprotein lipase, Phagocytes, Chemistry, Multiple sclerosis, Macrophages, angiopoietin-like 4, Brain, Middle Aged, medicine.disease, Lipid Metabolism, Cell biology, Lipoprotein Lipase, 030104 developmental biology, medicine.anatomical_structure, remyelination, lipoprotein-lipase, Female, lcsh:RC581-607, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6987cede47e908aea4ec1ed1b61df203Test
https://research.vumc.nl/en/publications/28d72115-5a11-429c-8392-29e7a172ecdfTest -
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المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, ACS - Microcirculation
المصدر: Glia
GLIA, 67(1), 68-77. John Wiley and Sons Inc.
Kamermans, A, Planting, K E, Jalink, K, van Horssen, J & de Vries, H E 2019, ' Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production ', GLIA, vol. 67, no. 1, pp. 68-77 . https://doi.org/10.1002/glia.23526Testمصطلحات موضوعية: 0301 basic medicine, Adult, Male, Multiple Sclerosis, Central nervous system, chondroitin sulfate proteoglycan, TRPM7, TRPM Cation Channels, Biology, Protein Serine-Threonine Kinases, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Transient receptor potential channel, 0302 clinical medicine, Downregulation and upregulation, medicine, Animals, Humans, Cells, Cultured, Research Articles, Aged, Aged, 80 and over, Neurons, Multiple sclerosis, Neurodegeneration, astrocytes, neurodegeneration, Middle Aged, medicine.disease, In vitro, Cell biology, Rats, 030104 developmental biology, medicine.anatomical_structure, Neurology, chemistry, Chondroitin Sulfate Proteoglycans, Chondroitin sulfate proteoglycan, Female, 030217 neurology & neurosurgery, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd28bb035a37c8aa45ffd980fc93a2fTest
https://pubmed.ncbi.nlm.nih.gov/30453391Test -
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المؤلفون: Jerome J. A. Hendriks, Elien Wouters, Winde Jorissen, Jeroen F. J. Bogie, Elien Grajchen, Jasmine Vanmol, Niels Hellings, Tim Vanmierlo, Jack van Horssen, Kristiaan Wouters, Jo Mailleux
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Multiple Sclerosis, Collectin, Mice, 03 medical and health sciences, Myelin, 0302 clinical medicine, Placenta, medicine, Animals, Humans, Myeloid Cells, Scavenger receptor, Receptor, Myelin Sheath, Receptors, Scavenger, Phagocytes, Multidisciplinary, Chemistry, Cell Membrane, Corrigenda, Collectins, Cell biology, Mice, Inbred C57BL, HEK293 Cells, RAW 264.7 Cells, 030104 developmental biology, medicine.anatomical_structure, embryonic structures, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296e80a9ae9d871dd5e61457f7de1486Test
https://doi.org/10.1038/srep46925Test -
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المؤلفون: Carsten Berndt, Klaudia Lepka, Orhan Aktas, Jens Ingwersen, Hans-Peter Hartung, Reiner Schneider, Natalia Rios, Arne Holmgren, Eckhard Bill, Rafael Radi, Thomas Hildebrandt, Katrin Volbracht, Timur Prozorovski, Lawrence Steinman, Jack van Horssen, Christopher Horst Lillig
المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation
المصدر: GLIA, 65(9), 1521-1534. John Wiley and Sons Inc.
Lepka, K, Volbracht, K, Bill, E, Schneider, R, Rios, N, Hildebrandt, T, Ingwersen, J, Prozorovski, T, Lillig, C H, van Horssen, J, Steinman, L, Hartung, H P, Radi, R, Holmgren, A, Aktas, O & Berndt, C 2017, ' Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia ', GLIA, vol. 65, no. 9, pp. 1521-1534 . https://doi.org/10.1002/glia.23178Testمصطلحات موضوعية: 0301 basic medicine, Encephalomyelitis, Autoimmune, Experimental, Biology, Nitric Oxide, Schistosoma japonicum, Nitric oxide, Tissue Culture Techniques, 03 medical and health sciences, Cellular and Molecular Neuroscience, Myelin, chemistry.chemical_compound, Neural Stem Cells, Glutaredoxin, Cerebellum, Peroxynitrous Acid, medicine, Escherichia coli, Animals, Humans, Neuroinflammation, Glutaredoxins, Myelin Sheath, Glutathione Transferase, Inflammation, Microglia, Nitrotyrosine, Experimental autoimmune encephalomyelitis, Glutaredoxin 2, medicine.disease, Neuroprotection, Recombinant Proteins, Cell biology, Mice, Inbred C57BL, Oligodendroglia, 030104 developmental biology, medicine.anatomical_structure, Neurology, Biochemistry, chemistry, Female, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5454e5144dbbaba6fdee28fbd68286cTest
https://research.vumc.nl/en/publications/59f0271e-5af8-4309-aa53-076692f28be2Test -
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المؤلفون: Micha M.M. Wilhelmus, Benjamin Drukarch, Jamie L. Lim, Jack van Horssen, Helga E. de Vries, Jeroen J.M. Hoozemans
المساهمون: Molecular cell biology and Immunology, Anatomy and neurosciences, Pathology, NCA - neurodegeneration
المصدر: Archives of Toxicology, 88(10), 1773-1786. Springer Verlag
Lim, J L, Wilhelmus, M M M, de Vries, H E, Drukarch, B, Hoozemans, J J M & van Horssen, J 2014, ' Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases ', Archives of Toxicology, vol. 88, no. 10, pp. 1773-1786 . https://doi.org/10.1007/s00204-014-1338-zTestمصطلحات موضوعية: Antioxidant, NF-E2-Related Factor 2, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Central nervous system, Disease, Biology, Toxicology, medicine.disease_cause, Antioxidants, medicine, Animals, Humans, Transcription factor, chemistry.chemical_classification, Reactive oxygen species, Mechanism (biology), Multiple sclerosis, Brain, Neurodegenerative Diseases, General Medicine, medicine.disease, Mitochondria, Disease Models, Animal, Oxidative Stress, medicine.anatomical_structure, chemistry, Immunology, Microglia, Reactive Oxygen Species, Neuroscience, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c3641d065bcaaedfdf64f6b1d521e7Test
https://doi.org/10.1007/s00204-014-1338-zTest -
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المؤلفون: Joost A. R. Drexhage, Paul van der Valk, Jack van Horssen, Susanne M. A. van der Pol, Helga E. de Vries, Mark R. Mizee, Bert van het Hof, Reina E. Mebius, Arie Reijerkerk, Philip G. Nijland
المساهمون: Molecular cell biology and Immunology, Pathology, NCA - Neuroinflamation
المصدر: Mizee, M R, Nijland, P G, van der Pol, S M A, Drexhage, J A R, Hof, B, Mebius, R, van der Valk, P, van Horssen, J, Reijerkerk, A & de Vries, H E 2014, ' Astrocyte-derived retinoic acid: a novel regulator of blood-brain barrier function in multiple sclerosis ', Acta Neuropathologica, vol. 128, no. 5, pp. 691-703 . https://doi.org/10.1007/s00401-014-1335-6Test
Acta Neuropathologica, 128(5), 691-703. Springer Verlagمصطلحات موضوعية: Adult, Male, Multiple Sclerosis, Time Factors, NF-E2-Related Factor 2, Retinoic acid, Tretinoin, Biology, Blood–brain barrier, medicine.disease_cause, Aldehyde Dehydrogenase 1 Family, Pathology and Forensic Medicine, Lesion, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Glial Fibrillary Acidic Protein, medicine, Humans, Cells, Cultured, Neuroinflammation, Aged, Aged, 80 and over, Multiple sclerosis, Brain, Endothelial Cells, Retinal Dehydrogenase, Aldehyde Dehydrogenase, Middle Aged, medicine.disease, Cell biology, HEK293 Cells, medicine.anatomical_structure, chemistry, Blood-Brain Barrier, Astrocytes, Immunology, Cytokines, Female, Autopsy, Neurology (clinical), medicine.symptom, Reactive Oxygen Species, Oxidative stress, Astrocyte, Morphogen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24674a1b925d6301e2322129110e260Test
https://doi.org/10.1007/s00401-014-1335-6Test