-
1
المؤلفون: Anne T. Nies, Elke Schaeffeler, Kathrin Klein, Kathleen M. Giacomini, Michel Eichelbaum, Matthias Schwab, Ute Hofmann, Claudia Neul, Stefan Winter
المصدر: British Journal of Pharmacology. 178:1459-1474
مصطلحات موضوعية: 0301 basic medicine, CYP2D6, SLC47A1, Organic Cation Transport Proteins, Pharmacology, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cations, medicine, Humans, Organic cation transport proteins, biology, Chemistry, Sparteine, Organic Cation Transporter 2, Cytochrome P450, Phenotype, 030104 developmental biology, Cytochrome P-450 CYP2D6, Pharmaceutical Preparations, Debrisoquine, Perhexiline, biology.protein, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3555d075053f2fad1daf3c8541155Test
https://doi.org/10.1111/bph.15370Test -
2
المؤلفون: Sebastian Raimundo, Ulrich M. Zanger, Matthias Schwab, Thomas Stüven, Joachim Fischer, Bernd Evert, Michel Eichelbaum
المصدر: Pharmacogenetics. 11:573-585
مصطلحات موضوعية: Polymorphism, Genetic, Genotype, Immunoblotting, Bufuralol, Gene Dosage, Biology, Phenotype, Molecular biology, Gene dosage, Recombinant Proteins, Isoenzymes, Variable Expression, chemistry.chemical_compound, Cytochrome P-450 CYP2D6, Liver, chemistry, Polymorphism (computer science), Gene expression, Genetics, Humans, General Pharmacology, Toxicology and Pharmaceutics, Allele, Promoter Regions, Genetic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1d6cfbdd9224734a2c54ede250ad4eTest
https://doi.org/10.1097/00008571-200110000-00004Test -
3
المؤلفون: Gerhard Schänzle, Klaus Eckhardt, Gerd Mikus, Shuxia Li, Michel Eichelbaum, Susanne Ammon
المصدر: Pain. 76:27-33
مصطلحات موضوعية: Adult, Male, Genotype, Metabolite, Analgesic, Population, Cmax, Pharmacology, chemistry.chemical_compound, Double-Blind Method, Pharmacokinetics, Humans, Medicine, education, Pain Measurement, education.field_of_study, Morphine, Codeine, business.industry, Analgesics, Opioid, Phenotype, Anesthesiology and Pain Medicine, Cytochrome P-450 CYP2D6, Neurology, Opioid, chemistry, Area Under Curve, Female, Neurology (clinical), business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db466013e2310322be7586f5a1a365c3Test
https://doi.org/10.1016/s0304-3959Test(98)00021-9 -
4
المؤلفون: Ulrich M. Zanger, Heinz Haubruck, Bernd Evert, Michel Eichelbaum
المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology. 355:309-318
مصطلحات موضوعية: CYP2D6, Insecta, In Vitro Techniques, Spodoptera, digestive system, chemistry.chemical_compound, Animals, Humans, Allele, skin and connective tissue diseases, Site-directed mutagenesis, Cells, Cultured, Pharmacology, Genetics, Polymorphism, Genetic, biology, Wild type, Cytochrome P450, General Medicine, Phenotype, Molecular biology, Rats, Isoenzymes, Kinetics, Cytochrome P-450 CYP2D6, Debrisoquine, chemistry, Mutagenesis, Microsomes, Liver, biology.protein, Electrophoresis, Polyacrylamide Gel, Baculoviridae, Pharmacogenetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde6fde45badfc34fb8e4100278e5b02Test
https://doi.org/10.1007/pl00004948Test -
5
المؤلفون: Heyo K. Kroemer, Christian Funck-Brentano, Michel Eichelbaum, Patrice Jaillon, Norbert G. Knebel, Kerstin Bühl, Laurent Becquemont
المصدر: Clinical Pharmacology and Therapeutics. 55:256-269
مصطلحات موضوعية: Adult, Male, CYP2D6, Metabolic Clearance Rate, Administration, Oral, Amiodarone, Pharmacology, Drug Administration Schedule, Mixed Function Oxygenases, Electrocardiography, Cytochrome P-450 Enzyme System, Pharmacokinetics, Reference Values, medicine, Humans, Drug Interactions, Pharmacology (medical), Flecainide, Analysis of Variance, Dose-Response Relationship, Drug, Chemistry, Genetic Variation, Dextromethorphan, Drug interaction, Crossover study, Phenotype, Cytochrome P-450 CYP2D6, Pharmacogenetics, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d666bea6a6bb5519697129934927c0fTest
https://doi.org/10.1038/clpt.1994.26Test -
6
المؤلفون: TD Arias, LF Jorge, Daniel W. Nebert, Michel Eichelbaum, Ulrich Griese
المصدر: Pharmacogenetics. 3:231-238
مصطلحات موضوعية: Male, CYP2D6, Genotype, Panama, Population genetics, Biology, Mixed Function Oxygenases, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Gene Frequency, Genetics, Humans, General Pharmacology, Toxicology and Pharmaceutics, Allele, Allele frequency, Alleles, Biological Evolution, Indians, Central American, Molecular biology, Phenotype, Cytochrome P-450 CYP2D6, Debrisoquine, chemistry, Multigene Family, Female, Restriction fragment length polymorphism, Variants of PCR, Polymorphism, Restriction Fragment Length, Pseudogenes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b397cfa7e7ac1423995a8f113abfba0Test
https://doi.org/10.1097/00008571-199310000-00002Test -
7
المؤلفون: Leif Bertilsson, Juliette Säwe, Q. Y. Yue, Marja-Liisa Dahl, Inger Johansson, C O Meese, Magnus Ingelman-Sundberg, Michel Eichelbaum
المصدر: Pharmacogenetics. 3:94-100
مصطلحات موضوعية: Quinidine, CYP2D6, Genotype, Metabolic Clearance Rate, CYP2D6 Gene, Biology, Hydroxylation, digestive system, White People, Mixed Function Oxygenases, chemistry.chemical_compound, Asian People, Cytochrome P-450 Enzyme System, Genetics, medicine, Cytochrome P-450 Enzyme Inhibitors, Humans, General Pharmacology, Toxicology and Pharmaceutics, Allele, skin and connective tissue diseases, Stereoisomerism, Phenotype, Debrisoquin, Cytochrome P-450 CYP2D6, Haplotypes, Debrisoquine, chemistry, Poor metabolizer, Polymorphism, Restriction Fragment Length, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3931c55dbb8bee1f6e6fbe8b23459a4eTest
https://doi.org/10.1097/00008571-199304000-00005Test -
8
المؤلفون: C R Wolf, J.S. Miles, Michel Eichelbaum, J.E. Moss, A.C. Gough, A Gaedigk, Nigel K. Spurr
المصدر: Nature. 347:773-776
مصطلحات موضوعية: CYP2D6, Lung Neoplasms, Cytochrome, CYP3A, Molecular Sequence Data, Locus (genetics), Biology, Polymerase Chain Reaction, Mixed Function Oxygenases, Cytochrome P-450 Enzyme System, Humans, Deoxyribonucleases, Type II Site-Specific, chemistry.chemical_classification, Genetics, Multidisciplinary, Base Sequence, Cytochrome P450, Monooxygenase, Phenotype, Enzyme, Cytochrome P-450 CYP2D6, Urinary Bladder Neoplasms, chemistry, Mutation, biology.protein, Polymorphism, Restriction Fragment Length
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3af67be12fceaa6032ef027570bec90Test
https://doi.org/10.1038/347773a0Test -
9
المؤلفون: Michel Eichelbaum, Ulrich M. Zanger, Sebastian Raimundo
المصدر: Naunyn-Schmiedeberg's archives of pharmacology. 369(1)
مصطلحات موضوعية: Pharmacology, Genetics, CYP2D6, Polymorphism, Genetic, General Medicine, Biology, Null allele, Substrate Specificity, chemistry.chemical_compound, Phenotype, Debrisoquine, chemistry, Cytochrome P-450 CYP2D6, Pharmaceutical Preparations, Pharmacogenomics, Genotype, Animals, Humans, Allele, Drug metabolism, Pharmacogenetics, Alleles, Biotransformation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b600247e9a5b31b771c886dff6dbd9e4Test
https://pubmed.ncbi.nlm.nih.gov/14618296Test -
10
المؤلفون: Peter Neuhaus, Michel Eichelbaum, Thomas E. Mürdter, Matthias Schwab, Claudia Marx, Kathrin Klein, Andreas K. Nussler, Ulrich M. Zanger, Monika Bredschneider
المصدر: Clinical pharmacology and therapeutics. 71(6)
مصطلحات موضوعية: Silent mutation, Genotype, Immunoblotting, Single-nucleotide polymorphism, Glutathione S-Transferase A1, Isozyme, Polymerase Chain Reaction, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, medicine, Humans, Pharmacology (medical), Promoter Regions, Genetic, Busulfan, DNA Primers, Glutathione Transferase, Pharmacology, Polymorphism, Genetic, biology, Haplotype, Glutathione, Molecular biology, Glutathione S-transferase, Phenotype, chemistry, Haplotypes, Multivariate Analysis, biology.protein, Immunosuppressive Agents, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee01f7ea6c1cec25b23e9143dbcb053Test
https://pubmed.ncbi.nlm.nih.gov/12087351Test