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المؤلفون: Rasmus Jorgensen, Luise Gram Schleiss, Kirsten Raun, Jacob Kofoed, Claus Bekker Jeppesen, Birgitte Schjellerup Wulff, Berit Østergaard Christoffersen, Jørgen Olsen, Lars Ynddal, Franziska Zosel, Ulrich Sensfuss, Johan F. Paulsson, Søren Østergaard, Jane Spetzler, Flemming S Nielsen
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reportsمصطلحات موضوعية: Swine, Science, Serum albumin, Peptide, Lipid-anchored protein, Medicinal chemistry, CHO Cells, Biochemistry, Article, Acylation, Lipopeptides, Cricetulus, In vivo, Cricetinae, Potency, Animals, Humans, Peptide YY, Obesity, chemistry.chemical_classification, Pharmacology, Lead optimization, Multidisciplinary, biology, Drug discovery, Fatty Acids, Albumin, Fatty acid, Acetylation, Liraglutide, Receptors, Neuropeptide Y, Drug Combinations, HEK293 Cells, chemistry, Drug delivery, biology.protein, Swine, Miniature, Medicine, Female, Anti-Obesity Agents, Peptides, Oligopeptides, Half-Life, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b070773ae97f4392dec87755c1751435Test
https://doaj.org/article/cec7ec4e645c44c5a30946919c1e7741Test -
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المؤلفون: Christian L. Roth, Oleg G. Chepurny, Bart C. De Jonghe, George G. Holz, Clinton Elfers, Kylie S. Chichura, Matthew R. Hayes, Tito Borner, Robert P. Doyle, Ian R. Sweet, Brandon T. Milliken
المصدر: J Med Chem
مصطلحات موضوعية: Blood Glucose, Male, Models, Molecular, Vomiting, Nausea, Neuropeptide, Peptide, Type 2 diabetes, Pharmacology, Binding, Competitive, 01 natural sciences, Article, Glucagon-Like Peptide-1 Receptor, Rats, Sprague-Dawley, Islets of Langerhans, Structure-Activity Relationship, 03 medical and health sciences, Weight loss, In vivo, Insulin Secretion, Weight Loss, Drug Discovery, medicine, Animals, Humans, Peptide YY, Receptor, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Shrews, medicine.disease, In vitro, Rats, Receptors, Neuropeptide Y, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Glucose, chemistry, Microsomes, Liver, Exenatide, Molecular Medicine, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f87628e79fa1735fd176ff82760e989Test
https://doi.org/10.1021/acs.jmedchem.0c01783Test -
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المؤلفون: A. Richard Chamberlin, A. John Yucel, Zachary R. Woydziak
المصدر: ChemMedChem
مصطلحات موضوعية: animal structures, Stereochemistry, Phosphatase, macromolecular substances, environment and public health, 01 natural sciences, Biochemistry, Article, Serine, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Protein Phosphatase 2, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Threonine, Furans, IC50, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Active site, Protein phosphatase 2, Lipids, Receptors, Neuropeptide Y, 0104 chemical sciences, enzymes and coenzymes (carbohydrates), 010404 medicinal & biomolecular chemistry, embryonic structures, biology.protein, Molecular Medicine, Tautomycin, Selectivity
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c41f38ec9e6986e89eb3b1be678f627Test
https://doi.org/10.1002/cmdc.202000801Test -
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المصدر: Chemmedchem
مصطلحات موضوعية: neuropeptide Y, media_common.quotation_subject, Peptide, cell lines, Ligands, 01 natural sciences, Biochemistry, law.invention, chemistry.chemical_compound, Biosynthesis, law, Very Important Paper, Cell Line, Tumor, Drug Discovery, cancer, Humans, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Internalization, media_common, G protein-coupled receptor, Fluorescent Dyes, Pharmacology, chemistry.chemical_classification, shuttling, Drug Carriers, Arrestin, Microscopy, Confocal, Full Paper, 010405 organic chemistry, Organic Chemistry, Full Papers, Ligand (biochemistry), 0104 chemical sciences, Receptors, Neuropeptide Y, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Targeted drug delivery, chemistry, Pharmaceutical Preparations, drug delivery, Recombinant DNA, Biophysics, Molecular Medicine, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb9bad27c063f76fd618dd2724d7666Test
http://europepmc.org/articles/PMC7818256Test -
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المؤلفون: Nobuaki Miyahara
المصدر: Folia Pharmacologica Japonica. 155:360-363
مصطلحات موضوعية: Mice, chemistry.chemical_compound, Immune system, mental disorders, Hypersensitivity, Animals, Humans, Medicine, Neuropeptide Y, Receptor, Neurotransmitter, Asthma, Inflammation, Pharmacology, business.industry, respiratory system, Neuropeptide Y receptor, medicine.disease, humanities, Pathophysiology, Receptors, Neuropeptide Y, respiratory tract diseases, medicine.anatomical_structure, chemistry, Peripheral nervous system, Immunology, business, Airway
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153da6595cdbb1b417c7b5bfe02cb155Test
https://doi.org/10.1254/fpj.20036Test -
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المؤلفون: Nora Klöting, Stefanie Wittrisch, Annette G. Beck-Sickinger, Matthias Blüher, Karin Mörl, Rima Chakaroun
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 31, Iss, Pp 163-180 (2020)
Mol. Metab. 31, 163-180 (2020)مصطلحات موضوعية: 0301 basic medicine, Molecular Conformation, Adipose tissue, Pharmacology, Adipocyte Targeting, Npy1r, Peptide Drug Conjugate, Tesaglitazar, Type 2 Diabetes, Mice, chemistry.chemical_compound, 0302 clinical medicine, tesa, tesaglitazar, Adipocyte, Chlorocebus aethiops, Adipocytes, FFA, free fatty acids, Cells, Cultured, Adipogenesis, Phenylpropionates, Cell Differentiation, Adipocyte targeting, Type 2 diabetes, NPY1R, neuropeptide Y1 receptor, tesa-NPY, [K4(GFLG-tesa), F7, P34]-NPY, Fabp4, fatty acid binding protein 4, NPY1R, COS Cells, Female, Original Article, Alkanesulfonates, Agonist, lcsh:Internal medicine, Cell type, medicine.drug_class, NPY, neuropeptide Y, T2D, type 2 diabetes, 030209 endocrinology & metabolism, Diabetes Mellitus, Experimental, Structure-Activity Relationship, 03 medical and health sciences, 3T3-L1 Cells, medicine, Animals, Humans, PPAR alpha, lcsh:RC31-1245, Molecular Biology, GPCR, G protein-coupled receptor, Mcp-1, monocyte chemotactic protein, Dose-Response Relationship, Drug, Adiponectin, Cell Biology, PPARα/γ, peroxisome proliferator-activated receptor alpha/gamma, Receptors, Neuropeptide Y, Mice, Inbred C57BL, PPAR gamma, HEK293 Cells, 030104 developmental biology, Diabetes Mellitus, Type 2, chemistry, Cell culture, Peptides, Cidec, cell death-inducing DEFA-like effector c, Peptide drug conjugate
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8a5984d3babe4cd79f900f950e2c37Test
https://doi.org/10.1016/j.molmet.2019.11.009Test -
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المؤلفون: Joshua A. Owens, Alexandra A. Wolfarth, Andrew S. Neish, Bindu Chandrasekharan, Bejan Saeedi, Darra Boyer, Heba Iskandar, Tanvi Dhere
المصدر: Inflamm Bowel Dis
مصطلحات موضوعية: Colon, medicine.medical_treatment, Biopsy, Pharmacology, Mice, Interferon, medicine, Immunology and Allergy, Animals, Humans, Colitis, Intestinal Mucosa, Receptor, Inflammation, Chemistry, Dextran Sulfate, Gastroenterology, Interleukin, Neuropeptide Y receptor, medicine.disease, Inflammatory Bowel Diseases, Corrigenda, Receptors, Neuropeptide Y, Cytokine, Cytokines, Tumor necrosis factor alpha, Leading Off, Ex vivo, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8017f9a0a6bee821680ec32a26aa10d7Test
https://pubmed.ncbi.nlm.nih.gov/34792116Test -
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المؤلفون: Leif K. Larsen, Henrik H. Hansen, Jacob Jelsing, Harald Tammen, Niels Vrang, Peter W. Haebel, Rikke V. Grônlund, Thomas Klein, Tamara Baader-Pagler
المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)مصطلحات موضوعية: 0301 basic medicine, Agonist, Male, medicine.medical_specialty, Combination therapy, medicine.drug_class, Science, Mice, Obese, 030209 endocrinology & metabolism, Linagliptin, Dipeptidyl peptidase, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Weight loss, Internal medicine, medicine, Animals, Pharmacology, Dipeptidyl-Peptidase IV Inhibitors, Multidisciplinary, Chemistry, digestive, oral, and skin physiology, Endocrine system and metabolic diseases, Receptors, Neuropeptide Y, 030104 developmental biology, Endocrinology, Anorectic, Medicine, medicine.symptom, Diet-induced obese, Homeostasis, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120fa05ea99ec2378256ffe043c674e3Test
https://pubmed.ncbi.nlm.nih.gov/33850212Test -
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المؤلفون: Isabel M Marrero, Carlos A. Perez-Heydrich, Todd E. Thiele, Kathryn J. Reissner, Marian T. Sepulveda-Orengo, Stacey L. Robinson
المصدر: Neuropsychopharmacology
مصطلحات موضوعية: Male, medicine.medical_specialty, Efferent, Population, Prefrontal Cortex, behavioral disciplines and activities, Article, Binge Drinking, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Limbic system, Internal medicine, Neural Pathways, medicine, Animals, Neuropeptide Y, Prefrontal cortex, Receptor, education, Pharmacology, education.field_of_study, Ethanol, Basolateral Nuclear Complex, Chemistry, musculoskeletal, neural, and ocular physiology, Neuropeptide Y receptor, Receptors, Neuropeptide Y, 030227 psychiatry, Mice, Inbred C57BL, Disease Models, Animal, Psychiatry and Mental health, medicine.anatomical_structure, Endocrinology, nervous system, Female, psychological phenomena and processes, 030217 neurology & neurosurgery, Basolateral amygdala
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3c5e136fec3080ee1ea69affd8570cTest
https://doi.org/10.1038/s41386-018-0310-7Test -
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المؤلفون: Hui Jia, Kamil Kuca, Dawei Guo, Wenda Wu, Eugenie Nepovimova, Qinghua Wu
المصدر: Toxicology. 452
مصطلحات موضوعية: 0301 basic medicine, Vomiting, Trichothecene, Neuropeptide, Pharmacology, Toxicology, Granisetron, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, biology.animal, medicine, Animals, Serotonin 5-HT3 Receptor Antagonists, Mink, Neurotransmitter, Receptor, biology, Dose-Response Relationship, Drug, business.industry, digestive, oral, and skin physiology, Receptors, Neuropeptide Y, 030104 developmental biology, chemistry, Peptide YY, Female, Serotonin, Receptors, Serotonin, 5-HT3, business, Emetics, Trichothecenes, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9206da46c9f349604294ccf83eec9096Test
https://pubmed.ncbi.nlm.nih.gov/33581213Test