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المؤلفون: Ross Chawner, Sonia Mazzitelli, Ross Jeggo, Claire E. Eyers, David Spanswick, Jasmeet Virdee, J. Mark Treherne, Alun Williams, David I.C. Scopes, Hozefa Amijee, Clive Bate, Andrew J. Doig
المصدر: Biochemistry. 51:8338-8352
مصطلحات موضوعية: Male, Programmed cell death, Circular dichroism, Cell Survival, Long-Term Potentiation, Peptide, Biochemistry, Oligomer, Mice, chemistry.chemical_compound, Alzheimer Disease, Lactate dehydrogenase, Tumor Cells, Cultured, Animals, Humans, Benzothiazoles, Protein Structure, Quaternary, Neurons, chemistry.chemical_classification, Amyloid beta-Peptides, Circular Dichroism, Long-term potentiation, Surface Plasmon Resonance, Peptide Fragments, Rats, Thiazoles, chemistry, Toxicity, Thioflavin, Protein Multimerization, Oligopeptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222e325f86e334145f0d7f75c2c725e9Test
https://doi.org/10.1021/bi300415vTest -
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المؤلفون: Victoria Ingham, Alun Williams, Clive Bate
المصدر: Neuropharmacology. 60:365-372
مصطلحات موضوعية: Gene isoform, Phospholipase A2 Inhibitors, Prions, Organophosphonates, Peptide, Arachidonic Acids, Biology, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Phospholipase A2, Animals, Humans, Receptor, Lipid raft, Cells, Cultured, Cerebral Cortex, Neurons, Pharmacology, chemistry.chemical_classification, Phospholipase A, Platelet-activating factor, Cholesterol, Peptide Fragments, Cell biology, Phospholipases A2, Protein Transport, chemistry, Biochemistry, biology.protein, lipids (amino acids, peptides, and proteins)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727fa08e89f717e9c89224629290d756Test
https://doi.org/10.1016/j.neuropharm.2010.10.001Test -
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المؤلفون: Mourad Tayebi, Alun Williams, Luisa Diomede, Clive Bate, Mario Salmona
المصدر: Neurotoxicity Research. 17:203-214
مصطلحات موضوعية: Simvastatin, Docosahexaenoic Acids, Prions, animal diseases, Synaptophysin, Enzyme-Linked Immunosorbent Assay, In Vitro Techniques, Hippocampal formation, Neurotransmission, Toxicology, Hippocampus, Synapse, Mice, Animals, Humans, Neurotoxin, Drug Interactions, Cells, Cultured, Cerebral Cortex, Mice, Knockout, Neurons, chemistry.chemical_classification, Dose-Response Relationship, Drug, biology, Caspase 3, General Neuroscience, Embryo, Mammalian, Eicosapentaenoic acid, Peptide Fragments, nervous system diseases, Cell biology, Neuroprotective Agents, Eicosapentaenoic Acid, Gene Expression Regulation, nervous system, chemistry, Biochemistry, Docosahexaenoic acid, Fatty Acids, Unsaturated, biology.protein, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, Synaptosomes, Polyunsaturated fatty acid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5351409a315ff0f09ced6daba2de3c03Test
https://doi.org/10.1007/s12640-009-9093-2Test -
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المؤلفون: Ronald S. Boshuizen, Clive Bate, Alun Williams
المصدر: Journal of Neuroimmunology. 170:62-70
مصطلحات موضوعية: Cell Survival, Prions, medicine.drug_class, Recombinant Fusion Proteins, CD14, Immunology, Lipopolysaccharide Receptors, Peptide, Monoclonal antibody, Antibodies, Monocytes, Epitope, Epitopes, Mice, Chimera (genetics), medicine, Animals, Humans, Immunology and Allergy, Cells, Cultured, Cerebral Cortex, Mice, Knockout, Neurons, chemistry.chemical_classification, Cell Death, biology, Antibodies, Monoclonal, Molecular biology, Coculture Techniques, Peptide Fragments, In vitro, Mice, Inbred C57BL, nervous system, Neurology, chemistry, Immunoglobulin G, Knockout mouse, biology.protein, Microglia, Neurology (clinical), Antibody, Epitope Mapping
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9620daf56f0981058c098de0d6c31155Test
https://doi.org/10.1016/j.jneuroim.2005.08.021Test -
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المؤلفون: Clive Bate, Scott Rutherford, Alun Williams, Mike B. Gravenor, Stuart Reid
المصدر: NeuroReport. 13:1933-1938
مصطلحات موضوعية: PrPSc Proteins, Cell Survival, Prions, animal diseases, Glutamic Acid, Prostaglandin, Biology, Dinoprostone, Prion Diseases, Mice, Neuroblastoma, chemistry.chemical_compound, Fetus, Tumor Cells, Cultured, medicine, Animals, Neurotoxin, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Cerebral Cortex, Neurons, chemistry.chemical_classification, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Microglia, General Neuroscience, Anti-Inflammatory Agents, Non-Steroidal, Neurotoxicity, Membrane Proteins, medicine.disease, Peptide Fragments, In vitro, nervous system diseases, Isoenzymes, Mice, Inbred C57BL, Neuroprotective Agents, medicine.anatomical_structure, Enzyme, Animals, Newborn, chemistry, Eicosanoid, Biochemistry, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Cyclooxygenase 1, Arachidonic acid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6aaf2fc0ce08de17c784ae58693083Test
https://doi.org/10.1097/00001756-200210280-00021Test -
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المؤلفون: Dirk Werling, Alun Williams
المساهمون: Williams, Alun [0000-0003-0835-0200], Apollo - University of Cambridge Repository
المصدر: BMC Neuroscience, Vol 13, Iss 1, p 106 (2012)
BMC Neuroscienceمصطلحات موضوعية: Time Factors, Phospholipases A2, Cytosolic, Synapse, Mice, Phospholipase A2, Tubulin, Drug Interactions, Enzyme Inhibitors, Cytoskeleton, Cells, Cultured, Cerebral Cortex, Neurons, Arachidonic Acid, biology, Cell Death, Chemistry, General Neuroscience, Ionomycin, Neurodegeneration, lcsh:QP351-495, Ketones, Cell biology, Protein Transport, Tetradecanoylphorbol Acetate, lipids (amino acids, peptides, and proteins), Intracellular, Research Article, Neurite, Prions, Synaptophysin, Tritium, PACOCF3, lcsh:RC321-571, Cellular and Molecular Neuroscience, medicine, Neurotoxicity, Animals, Humans, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Analysis of Variance, Dose-Response Relationship, Drug, medicine.disease, Embryo, Mammalian, Peptide Fragments, Enzyme Activation, lcsh:Neurophysiology and neuropsychology, Gene Expression Regulation, biology.protein
وصف الملف: text/xml; application/pdf; image/tiff
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bd5d5bea60e0331f0cb4a95c3cf7a1Test
http://www.biomedcentral.com/1471-2202/13/106Test -
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المؤلفون: Clive Bate, Luisa Diomede, Mario Salmona, Victoria Marshall, Laura Colombo, Alun Williams
المصدر: Neuropharmacology. 54(6)
مصطلحات موضوعية: medicine.medical_specialty, Docosahexaenoic Acids, Prions, Caveolin 1, Enzyme-Linked Immunosorbent Assay, Nerve Tissue Proteins, Dinoprostone, Cellular and Molecular Neuroscience, Mice, Phospholipase A2, Internal medicine, medicine, Animals, Cognitive decline, Prostaglandin E2, Lipid raft, Cells, Cultured, Pharmacology, chemistry.chemical_classification, Neurons, Amyloid beta-Peptides, biology, Cell Death, Dose-Response Relationship, Drug, Caspase 3, Neurotoxicity, medicine.disease, Eicosapentaenoic acid, Peptide Fragments, Phospholipases A2, Endocrinology, Cholesterol, chemistry, Biochemistry, Eicosapentaenoic Acid, Docosahexaenoic acid, biology.protein, lipids (amino acids, peptides, and proteins), Polyunsaturated fatty acid, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff4c46f49ad761cd590d1438c022818Test
https://pubmed.ncbi.nlm.nih.gov/18355880Test -
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المؤلفون: Clive Bate, Sarah L. Kempster, Alun Williams
المصدر: Neuropharmacology. 51(2)
مصطلحات موضوعية: CD14, Recombinant Fusion Proteins, Receptors, Prostaglandin, Lipopolysaccharide Receptors, Biology, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, medicine, Animals, Platelet Activating Factor, Receptors, Immunologic, Receptor, Cells, Cultured, Pharmacology, Cerebral Cortex, Mice, Knockout, Neurons, Amyloid beta-Peptides, Microglia, Platelet-activating factor, Cell Death, Antagonist, Neurotoxicity, Prostanoid, respiratory system, medicine.disease, Coculture Techniques, Peptide Fragments, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, Neuroprotective Agents, nervous system, Biochemistry, chemistry, Immunoglobulin G, Second messenger system, lipids (amino acids, peptides, and proteins), Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1352f59c28db0ca0bc44ffd9791d120Test
https://pubmed.ncbi.nlm.nih.gov/16678220Test -
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المؤلفون: Alun Williams, Clive Bate, Mario Salmona
المصدر: Neuroreport. 15(3)
مصطلحات موضوعية: Amyloid beta, Prions, animal diseases, Pharmacology, Dinoprostone, Phospholipases A, chemistry.chemical_compound, Neuroblastoma, Phospholipase A2, medicine, Tumor Cells, Cultured, Humans, Prostaglandin E2, Platelet Activating Factor, Phospholipase A, Amyloid beta-Peptides, biology, Platelet-activating factor, Cell Death, Brain Neoplasms, Caspase 3, General Neuroscience, Neurodegeneration, Neurotoxicity, medicine.disease, Peptide Fragments, nervous system diseases, Phospholipases A2, Biochemistry, chemistry, Caspases, biology.protein, Alzheimer's disease, Nervous System Diseases, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b9872898e204e9f74c85f3eb564efbTest
https://pubmed.ncbi.nlm.nih.gov/15094513Test -
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المؤلفون: Jan P. M. Langeveld, Rob H. Meloen, Ronald S. Boshuizen, Johannes P. M. Langedijk, Mario Salmona, Alun Williams
المصدر: Analytical Biochemistry, 333(2), 372-380
Analytical Biochemistry 333 (2004) 2مصطلحات موضوعية: Models, Molecular, Time Factors, Amyloid, Prions, Molecular Sequence Data, Biophysics, Drug Evaluation, Preclinical, Scrapie, Peptide, Biology, cultured-cells, Fibril, Biochemistry, Sensitivity and Specificity, chemistry.chemical_compound, dextran sulfate, Humans, Amino Acid Sequence, Benzothiazoles, alzheimers-disease, congo red, CIDC - Divisie Bacteriologie en TSE's, Molecular Biology, Peptide sequence, Fluorescent Dyes, chemistry.chemical_classification, prp, Staining and Labeling, molecular-cloning, scrapie, Reproducibility of Results, Neurodegenerative Diseases, Cell Biology, Tetracycline, thioflavine-t, In vitro, Peptide Fragments, Congo red, nervous system diseases, Transmembrane domain, Thiazoles, branched polyamines, chemistry, stained amyloid fibrils, Neurofibrils, Gelatin
وصف الملف: application/octet-stream; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f24566fc784506917975ab0dd3679e6Test
https://research.wur.nl/en/publications/an-in-vitro-screening-assay-based-on-synthetic-prion-protein-peptTest