نتائج البحث - "Receptors, Neuropeptide Y"

1

Exogenous orexin-A downregulates luteinizing hormone secretory activity in prepubertal female rats

المؤلفون: Anna Litwiniuk, Wojciech Bik, Boguslawa Baranowska, Małgorzata Kalisz, Alina Gajewska, Lidia Martynska, Magdalena Chmielowska

المصدر: Endokrynologia Polska. 72:238-242

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ea3d66cecc37091dc69f8f074fa156Test
https://doi.org/10.5603/ep.a2021.0041Test

2

NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression

المؤلفون: Nora Klöting, Stefanie Wittrisch, Annette G. Beck-Sickinger, Matthias Blüher, Karin Mörl, Rima Chakaroun

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 31, Iss, Pp 163-180 (2020)
Mol. Metab. 31, 163-180 (2020)

مصطلحات موضوعية: 0301 basic medicine, Molecular Conformation, Adipose tissue, Pharmacology, Adipocyte Targeting, Npy1r, Peptide Drug Conjugate, Tesaglitazar, Type 2 Diabetes, Mice, chemistry.chemical_compound, 0302 clinical medicine, tesa, tesaglitazar, Adipocyte, Chlorocebus aethiops, Adipocytes, FFA, free fatty acids, Cells, Cultured, Adipogenesis, Phenylpropionates, Cell Differentiation, Adipocyte targeting, Type 2 diabetes, NPY1R, neuropeptide Y1 receptor, tesa-NPY, [K4(GFLG-tesa), F7, P34]-NPY, Fabp4, fatty acid binding protein 4, NPY1R, COS Cells, Female, Original Article, Alkanesulfonates, Agonist, lcsh:Internal medicine, Cell type, medicine.drug_class, NPY, neuropeptide Y, T2D, type 2 diabetes, 030209 endocrinology & metabolism, Diabetes Mellitus, Experimental, Structure-Activity Relationship, 03 medical and health sciences, 3T3-L1 Cells, medicine, Animals, Humans, PPAR alpha, lcsh:RC31-1245, Molecular Biology, GPCR, G protein-coupled receptor, Mcp-1, monocyte chemotactic protein, Dose-Response Relationship, Drug, Adiponectin, Cell Biology, PPARα/γ, peroxisome proliferator-activated receptor alpha/gamma, Receptors, Neuropeptide Y, Mice, Inbred C57BL, PPAR gamma, HEK293 Cells, 030104 developmental biology, Diabetes Mellitus, Type 2, chemistry, Cell culture, Peptides, Cidec, cell death-inducing DEFA-like effector c, Peptide drug conjugate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8a5984d3babe4cd79f900f950e2c37Test
https://doi.org/10.1016/j.molmet.2019.11.009Test

3

Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice

المؤلفون: Leif K. Larsen, Henrik H. Hansen, Jacob Jelsing, Harald Tammen, Niels Vrang, Peter W. Haebel, Rikke V. Grônlund, Thomas Klein, Tamara Baader-Pagler

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120fa05ea99ec2378256ffe043c674e3Test
https://pubmed.ncbi.nlm.nih.gov/33850212Test

4

NPY Receptor 2 Mediates NPY Antidepressant Effect in the mPFC of LPS Rat by Suppressing NLRP3 Signaling Pathway

المؤلفون: Wenjiao Wang, Xinyue Chen, Tao Xu, Cuige Shi, Jing Sun, Yutao Yang, Zhi-Qing David Xu, Hui Li, Chunkai Du, Xiaoxiao Li, Kemeng Dong

المصدر: Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be9fac5662443d15913234942fa10ddTest
https://doi.org/10.1155/2019/7898095Test

5

An insurmountable NPY Y5 receptor antagonist exhibits superior anti-obesity effects in high-fat diet-induced obese mice

المؤلفون: Hirohide Nambu, Hideo Yukioka, Atsushi Obata, Takayuki Okuno, Hideki Tanioka, Yumiko Fukasaka, Misato Tonomura

المصدر: Neuropeptides. 70:55-63

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b457020fa050b80a964ffdb13d0b01Test
https://doi.org/10.1016/j.npep.2018.05.006Test

6

Increase in neuropeptide Y activity impairs social behaviour in association with glutamatergic dysregulation in diabetic mice

المؤلفون: Naomi Yonemochi, Tomohiro Kamata, John L. Waddington, Masahiro Shibasaki, Hiroko Ikeda, Junzo Kamei, Daiki Ueda

المصدر: British journal of pharmacologyREFERENCES. 178(3)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e08343a1fd8e398ccb0ab00ee850e36Test
https://pubmed.ncbi.nlm.nih.gov/35971963Test

7

Development and characterisation of a peptidergic N-and C-terminally stabilised mammalian NPY1R agonist which protects against diabetes induction

المؤلفون: Neil Tanday, Ryan A. Lafferty, Peter R. Flatt, Nigel Irwin

المصدر: Biochimica et biophysica acta. General subjects. 1864(5)

مصطلحات موضوعية: 0301 basic medicine, Agonist, Fish Proteins, Male, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Biophysics, Neuropeptide, 030209 endocrinology & metabolism, Protective Agents, Biochemistry, Glucagon, Cell Line, Diabetes Mellitus, Experimental, 03 medical and health sciences, Mice, 0302 clinical medicine, Internal medicine, Insulin-Secreting Cells, medicine, Animals, Hypoglycemic Agents, Insulin, Petromyzon, Molecular Biology, geography, geography.geographical_feature_category, biology, Chemistry, Lamprey, digestive, oral, and skin physiology, biology.organism_classification, Islet, Endopeptidase, Receptors, Neuropeptide Y, 030104 developmental biology, Endocrinology, Beta cell, Peptides, human activities, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824e8aa0f1579c02e0c2cc67fc57d982Test
https://pubmed.ncbi.nlm.nih.gov/32007578Test

8

The effect of peptide tyrosine tyrosine (PYY3-36), a selective Y2 receptor agonist on streptozotocin-induced diabetes in albino rats

المؤلفون: Mona M. I. Abdalla, Rasha F. Ahmed, Nagwa M. Zenhom, Heba A. Abdel-Hamid

المصدر: Endocrine Regulations, Vol 53, Iss 1, Pp 26-33 (2019)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, pyy, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, chemistry.chemical_compound, Eating, 0302 clinical medicine, Endocrinology, Adiposity, Glycogen, high fat diet, Organ Size, Neuropeptide Y receptor, medicine.drug, Agonist, medicine.medical_specialty, medicine.drug_class, Drinking, 030209 endocrinology & metabolism, Intra-Abdominal Fat, Diseases of the endocrine glands. Clinical endocrinology, Streptozocin, Diabetes Mellitus, Experimental, 03 medical and health sciences, Insulin resistance, nf-κb and npy, Internal medicine, Diabetes mellitus, medicine, Animals, Peptide YY, Rats, Wistar, business.industry, Insulin, Body Weight, nutritional and metabolic diseases, Type 2 Diabetes Mellitus, RC648-665, medicine.disease, Streptozotocin, Peptide Fragments, Rats, Receptors, Neuropeptide Y, 030104 developmental biology, chemistry, Insulin Resistance, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e4605bde1090ad4e2177d795e55a24Test
https://pubmed.ncbi.nlm.nih.gov/31517617Test

9

Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model

المؤلفون: Eduardo Souza-Silva, Carlos Rogério Tonussi, Lucas Mascarin, Maíra A. Bicca, Fabiana N Dornelles, Taciane Stein

المصدر: Brain research. 1735

مصطلحات موضوعية: 0301 basic medicine, Agonist, Male, Nociception, Knee Joint, medicine.drug_class, Pyridines, Pain, Pharmacology, Injections, Intra-Articular, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Neurotoxin, Animals, Neuropeptide Y, Rats, Wistar, Molecular Biology, Injections, Spinal, Pain Measurement, 2-Pyridylethylamine, Analgesics, General Neuroscience, Antagonist, Neuropeptide Y receptor, Spinal cord, Arthralgia, Spine, Hindlimb, Rats, Receptors, Neuropeptide Y, 030104 developmental biology, medicine.anatomical_structure, chemistry, Spinal Cord, Receptors, Histamine, Neurology (clinical), 030217 neurology & neurosurgery, Histamine, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cb1968f39efdcfb0df3cf850125679Test
https://pubmed.ncbi.nlm.nih.gov/32135147Test

10

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, Agonist, Dihydropyridines, medicine.drug_class, Inositol Phosphates, Arginine, Crystallography, X-Ray, Ligands, Article, Substrate Specificity, Structure-Activity Relationship, 03 medical and health sciences, medicine, Humans, Neuropeptide Y, Receptor, Diphenylacetic Acids, Nuclear Magnetic Resonance, Biomolecular, Binding Sites, Multidisciplinary, 030102 biochemistry & molecular biology, Drug discovery, Chemistry, Phenylurea Compounds, Neuropeptide Y receptor, Ligand (biochemistry), Receptors, Neuropeptide Y, 3. Good health, Molecular Docking Simulation, N-terminus, 030104 developmental biology, Biochemistry, Peptide YY, Mutation, Mutant Proteins, Endogenous agonist, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c7c85e188410a47148a2b5ceedc71fTest
https://doi.org/10.1038/s41586-018-0046-xTest

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