Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status
| العنوان: | Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status |
|---|---|
| المؤلفون: | Ali Sheikhy, Hedyeh Saneifard, Marjan Shakiba, Aida Fallahzadeh, Leila Baniadam, Fatemeh Abdollah Gorji |
| المصدر: | Nutrition and Metabolic Insights Nutrition and Metabolic Insights, Vol 14 (2021) |
| بيانات النشر: | SAGE Publications, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Vitamin, medicine.medical_specialty, puberty, obesity, RC620-627, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, 25(OH)2D3, vitamin D deficiency, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Vitamin D and neurology, TX341-641, Original Study, 030212 general & internal medicine, Nutritional diseases. Deficiency diseases, Nutrition and Dietetics, Nutrition. Foods and food supply, business.industry, medicine.disease, Obesity, Endocrinology, chemistry, business, season, Food Science |
| الوصف: | Background: Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity. Objective: The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level. Method: A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020. Results: 220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, P < .001). Mean vitamin D level was lower in obese children compared with non-obese ( P < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) ( P = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) ( P = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls ( P < .001). Conclusion: Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups. |
| اللغة: | English |
| تدمد: | 1178-6388 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91802bf9911e5d6da8c620fc5432ee20Test http://europepmc.org/articles/PMC8161864Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....91802bf9911e5d6da8c620fc5432ee20 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 11786388 |
|---|