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المؤلفون: Anne T. Nies, Elke Schaeffeler, Kathrin Klein, Kathleen M. Giacomini, Michel Eichelbaum, Matthias Schwab, Ute Hofmann, Claudia Neul, Stefan Winter
المصدر: British Journal of Pharmacology. 178:1459-1474
مصطلحات موضوعية: 0301 basic medicine, CYP2D6, SLC47A1, Organic Cation Transport Proteins, Pharmacology, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cations, medicine, Humans, Organic cation transport proteins, biology, Chemistry, Sparteine, Organic Cation Transporter 2, Cytochrome P450, Phenotype, 030104 developmental biology, Cytochrome P-450 CYP2D6, Pharmaceutical Preparations, Debrisoquine, Perhexiline, biology.protein, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3555d075053f2fad1daf3c8541155Test
https://doi.org/10.1111/bph.15370Test -
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المؤلفون: Michel Eichelbaum, Astrid Nörenberg, Maria Thomas, Ulrich M. Zanger, Werner Schroth, Thomas E. Mürdter, Hiltrud Brauch, Matthias Schwab, Janina Johänning, Patrick Kröner
المصدر: Archives of Toxicology
مصطلحات موضوعية: CYP2B6, Bisphenol, Health, Toxicology and Mutagenesis, Metabolite, Glucuronidation, Estrogen receptor, Gene induction, Pharmacology, Alkenes, Toxicology, 030226 pharmacology & pharmacy, Gene Expression Regulation, Enzymologic, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Glucuronides, Cytochrome P-450 Enzyme System, Phenols, medicine, Humans, Glucuronosyltransferase, skin and connective tissue diseases, ADME, CYP3A4, Estrogens, General Medicine, Tamoxifen, Metabolism, Estrogen-like metabolites, chemistry, 030220 oncology & carcinogenesis, Hepatocytes, Microsomes, Liver, hormones, hormone substitutes, and hormone antagonists, CYP activity, medicine.drug, Toxicokinetics and Metabolism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8044be80adc4584bdb07a4964bc05dTest
http://europepmc.org/articles/PMC5866846Test -
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المؤلفون: Werner Schroth, Stefan Winter, Thomas Mürdter, Elke Schaeffeler, Diana Eccles, Bryony Eccles, Balram Chowbay, Chiea C. Khor, Arafat Tfayli, Nathalie K. Zgheib, Michel Eichelbaum, Matthias Schwab, Hiltrud Brauch
المصدر: Frontiers in Pharmacology, Vol 8 (2017)
Frontiers in Pharmacologyمصطلحات موضوعية: medicine.medical_specialty, CYP2D6, Metabolite, Estrogen receptor, Biology, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Breast cancer, breast cancer, Internal medicine, Genotype, medicine, Pharmacology (medical), Allele, skin and connective tissue diseases, Original Research, Pharmacology, tamoxifen, lcsh:RM1-950, metabolizer phenotype, Desmethyl, medicine.disease, Endocrinology, lcsh:Therapeutics. Pharmacology, chemistry, CYP2D6 polymorphism, 030220 oncology & carcinogenesis, endoxifen, Tamoxifen, medicine.drug
وصف الملف: text
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3d4f1ffff791888c186c77930757d0Test
http://journal.frontiersin.org/article/10.3389/fphar.2017.00582/fullTest -
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المؤلفون: Georg Heinkele, Jana C. Precht, Matthias Schwab, Michel Eichelbaum, Hiltrud Brauch, Werner Schroth, Janina Johänning, Thomas E. Mürdter
المصدر: Analytical and Bioanalytical Chemistry. 407:7497-7502
مصطلحات موضوعية: Antineoplastic Agents, Hormonal, Bisphenol, medicine.drug_class, medicine.medical_treatment, Breast Neoplasms, Estrone, Biochemistry, Analytical Chemistry, Steroid, chemistry.chemical_compound, Limit of Detection, Tandem Mass Spectrometry, medicine, Humans, Androstenedione, Solid phase extraction, Chromatography, Chemistry, Selected reaction monitoring, Postmenopause, Tamoxifen, Estrogen, Female, hormones, hormone substitutes, and hormone antagonists, Chromatography, Liquid, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d10265cba912937d18a951bab1e5e5eTest
https://doi.org/10.1007/s00216-015-8907-8Test -
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المؤلفون: Alexander Teml, Christian Schäfer, Maarit Rein, Gema Pereira-Caro, Antoine Lévèques, Alan Crozier, Ute Hofmann, Tristan P. Dew, Matthias Schwab, Lucas Actis-Goretta, Gary Williamson, Michel Eichelbaum
المصدر: Molecular Nutrition & Food Research. 59:1651-1662
مصطلحات موضوعية: Adult, Male, Brush border, Biological Availability, Blood Pressure, Pharmacology, Intestinal absorption, Body Mass Index, Excretion, Young Adult, chemistry.chemical_compound, Hesperidin, Glucoside, In vivo, Humans, Single-Blind Method, Cross-Over Studies, Hesperetin, Metabolism, Healthy Volunteers, chemistry, Biochemistry, Gastrointestinal Absorption, Female, Food Science, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8321ffc423c3a4901ed1ea2fd72950c7Test
https://doi.org/10.1002/mnfr.201500202Test -
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المؤلفون: Matthias Schwab, Stefan Winter, Peter A. Fasching, Georg Heinkele, Hiltrud Brauch, Thomas E. Mürdter, L Bacchus‐Gerybadze, Werner Schroth, W. Simon, Tanja Fehm, Michel Eichelbaum
المصدر: Clinical Pharmacology & Therapeutics. 89:708-717
مصطلحات موضوعية: Adult, medicine.medical_specialty, UGT1A4, CYP2B6, Metabolite, Estrogen receptor, Biology, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Internal medicine, medicine, Humans, Pharmacology (medical), Prospective Studies, Glucuronosyltransferase, skin and connective tissue diseases, IC50, Aged, Aged, 80 and over, Pharmacology, Polymorphism, Genetic, Biological activity, Middle Aged, UGT2B7, Cytochrome P-450 CYP2C19, Tamoxifen, Endocrinology, Cytochrome P-450 CYP2D6, Receptors, Estrogen, chemistry, Female, Aryl Hydrocarbon Hydroxylases, Follow-Up Studies, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08057486b74af3ba45820042cacda1eTest
https://doi.org/10.1038/clpt.2011.27Test -
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المؤلفون: David W. Haas, Elke Schaeffeler, Gregory K. Robbins, David B. Clifford, Ulrich M. Zanger, Edward P. Acosta, Marylyn D. Ritchie, Roy M. Gulick, Michel Eichelbaum, Matthias Schwab, Huan Liu, Alison A. Motsinger-Reif, Heather J. Ribaudo, Gene D. Morse
المصدر: The Journal of Infectious Diseases. 202:717-722
مصطلحات موضوعية: Cyclopropanes, Male, Oncology, medicine.medical_specialty, ATP Binding Cassette Transporter, Subfamily B, Efavirenz, Anti-HIV Agents, Black People, HIV Infections, Pharmacology, Biology, Polymorphism, Single Nucleotide, White People, Article, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, Genotype, medicine, Cytochrome P-450 CYP3A, Humans, Immunology and Allergy, ATP Binding Cassette Transporter, Subfamily B, Member 1, CYP3A5, Oxidoreductases, N-Demethylating, Hispanic or Latino, Stepwise regression, Benzoxazines, Clinical trial, Cytochrome P-450 CYP2B6, Treatment Outcome, Infectious Diseases, chemistry, Pharmacogenetics, Alkynes, Reverse Transcriptase Inhibitors, Female, Aryl Hydrocarbon Hydroxylases, Body mass index
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4feee22b9353e06073d44582f08b5458Test
https://doi.org/10.1086/655470Test -
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المؤلفون: Heike Tegude, Ulrike Gradhand, Martin F. Fromm, Jörg König, Michel Eichelbaum, Oliver Burk
المصدر: Life Sciences. 80:1490-1494
مصطلحات موضوعية: Regulatory Sequences, Nucleic Acid, Transfection, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Genes, Reporter, Complementary DNA, Humans, Cloning, Molecular, General Pharmacology, Toxicology and Pharmaceutics, Luciferases, Gene, DNA Primers, Analysis of Variance, Messenger RNA, Reporter gene, biology, General Medicine, Molecular biology, chemistry, Regulatory sequence, ABCC3, biology.protein, Multidrug Resistance-Associated Proteins, Cytosine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9dcc1c4dc67bfc5a7bf4a29cafaa2bTest
https://doi.org/10.1016/j.lfs.2007.01.023Test -
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المصدر: Breast Cancer Research and Treatment. 107:15-24
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Metabolite, Estrogen receptor, Breast Neoplasms, Protein Serine-Threonine Kinases, Biology, Transforming Growth Factor beta2, chemistry.chemical_compound, Cell Line, Tumor, Internal medicine, Biomarkers, Tumor, medicine, Humans, RNA, Messenger, skin and connective tissue diseases, Cell Proliferation, Receptor, Transforming Growth Factor-beta Type II, Cancer, Estrogens, Transforming growth factor beta, Antiestrogen, medicine.disease, Tamoxifen, Endocrinology, Models, Chemical, Oncology, chemistry, Selective estrogen receptor modulator, Cancer cell, Cancer research, biology.protein, Receptors, Transforming Growth Factor beta, Biomarkers, hormones, hormone substitutes, and hormone antagonists, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fec4a285a569846f31abf7cbfb12d50Test
https://doi.org/10.1007/s10549-007-9526-7Test -
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المؤلفون: Michel Eichelbaum, Klaus von Bergmann, Dieter Lütjohann, Mikko Niemi, Michael Igel, Kari T. Kivistö, Ute Hofmann, Katja A. Arnold, Matthias Schwab
المصدر: Clinical Pharmacology & Therapeutics. 79:419-426
مصطلحات موضوعية: Adult, medicine.medical_specialty, Organic anion transporter 1, Organic Anion Transporters, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, medicine, Humans, Pharmacology (medical), Prospective Studies, Pravastatin, Pharmacology, Polymorphism, Genetic, biology, Liver-Specific Organic Anion Transporter 1, Cholesterol, Cholesterol, LDL, Confidence interval, Organic anion-transporting polypeptide, Endocrinology, Haplotypes, chemistry, Biochemistry, Pharmacogenetics, Area Under Curve, biology.protein, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, SLCO1B1, Half-Life, Lipoprotein, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8d1067c789c20c065cbd8eea23e6fbTest
https://doi.org/10.1016/j.clpt.2006.01.010Test