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المؤلفون: Rasmus Jorgensen, Luise Gram Schleiss, Kirsten Raun, Jacob Kofoed, Claus Bekker Jeppesen, Birgitte Schjellerup Wulff, Berit Østergaard Christoffersen, Jørgen Olsen, Lars Ynddal, Franziska Zosel, Ulrich Sensfuss, Johan F. Paulsson, Søren Østergaard, Jane Spetzler, Flemming S Nielsen
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reportsمصطلحات موضوعية: Swine, Science, Serum albumin, Peptide, Lipid-anchored protein, Medicinal chemistry, CHO Cells, Biochemistry, Article, Acylation, Lipopeptides, Cricetulus, In vivo, Cricetinae, Potency, Animals, Humans, Peptide YY, Obesity, chemistry.chemical_classification, Pharmacology, Lead optimization, Multidisciplinary, biology, Drug discovery, Fatty Acids, Albumin, Fatty acid, Acetylation, Liraglutide, Receptors, Neuropeptide Y, Drug Combinations, HEK293 Cells, chemistry, Drug delivery, biology.protein, Swine, Miniature, Medicine, Female, Anti-Obesity Agents, Peptides, Oligopeptides, Half-Life, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b070773ae97f4392dec87755c1751435Test
https://doaj.org/article/cec7ec4e645c44c5a30946919c1e7741Test -
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المؤلفون: Christian L. Roth, Oleg G. Chepurny, Bart C. De Jonghe, George G. Holz, Clinton Elfers, Kylie S. Chichura, Matthew R. Hayes, Tito Borner, Robert P. Doyle, Ian R. Sweet, Brandon T. Milliken
المصدر: J Med Chem
مصطلحات موضوعية: Blood Glucose, Male, Models, Molecular, Vomiting, Nausea, Neuropeptide, Peptide, Type 2 diabetes, Pharmacology, Binding, Competitive, 01 natural sciences, Article, Glucagon-Like Peptide-1 Receptor, Rats, Sprague-Dawley, Islets of Langerhans, Structure-Activity Relationship, 03 medical and health sciences, Weight loss, In vivo, Insulin Secretion, Weight Loss, Drug Discovery, medicine, Animals, Humans, Peptide YY, Receptor, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Shrews, medicine.disease, In vitro, Rats, Receptors, Neuropeptide Y, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Glucose, chemistry, Microsomes, Liver, Exenatide, Molecular Medicine, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f87628e79fa1735fd176ff82760e989Test
https://doi.org/10.1021/acs.jmedchem.0c01783Test -
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المصدر: Chemmedchem
مصطلحات موضوعية: neuropeptide Y, media_common.quotation_subject, Peptide, cell lines, Ligands, 01 natural sciences, Biochemistry, law.invention, chemistry.chemical_compound, Biosynthesis, law, Very Important Paper, Cell Line, Tumor, Drug Discovery, cancer, Humans, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Internalization, media_common, G protein-coupled receptor, Fluorescent Dyes, Pharmacology, chemistry.chemical_classification, shuttling, Drug Carriers, Arrestin, Microscopy, Confocal, Full Paper, 010405 organic chemistry, Organic Chemistry, Full Papers, Ligand (biochemistry), 0104 chemical sciences, Receptors, Neuropeptide Y, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Targeted drug delivery, chemistry, Pharmaceutical Preparations, drug delivery, Recombinant DNA, Biophysics, Molecular Medicine, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb9bad27c063f76fd618dd2724d7666Test
http://europepmc.org/articles/PMC7818256Test -
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المؤلفون: Jens Meiler, Oanh Vu, Clara T. Schoeder, Simone Prömel, Victoria Elisabeth Groß, Anette Kaiser, Miron Mikhailowitsch Gershkovich
المصدر: J Mol Biol
مصطلحات موضوعية: Models, Molecular, Amino Acid Motifs, Peptide binding, Peptide, Article, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Animals, Humans, Neuropeptide Y, Amino Acid Sequence, Receptor, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, biology, Chemistry, Glutamate receptor, Neuropeptide Y receptor, biology.organism_classification, Ligand (biochemistry), Cell biology, Receptors, Neuropeptide Y, Mutation, Protostome, Salt bridge, 030217 neurology & neurosurgery, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22735864b593e2a34f525070c42afb41Test
https://europepmc.org/articles/PMC8380825Test/ -
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المصدر: Biological Chemistry. 400:299-311
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Clinical Biochemistry, Neuropeptide, Peptide, Disease, Biology, Peptide hormone, Neuropeptide Y receptor, Biochemistry, Receptors, Neuropeptide Y, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, chemistry, Neoplasms, Peptide YY, Humans, Pancreatic polypeptide, Neuropeptide Y, Receptor, Molecular Biology, Neuroscience, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fd10ad136c552ac2819366dda06930Test
https://doi.org/10.1515/hsz-2018-0364Test -
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المؤلفون: Ryan A. Lafferty, Peter R. Flatt, Neil Tanday, Nigel Irwin
المصدر: Metabolism: clinical and experimental. 111
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, Dipeptidyl Peptidase 4, Neuropeptide, 030209 endocrinology & metabolism, Peptide, Glucagon, Cell Line, 03 medical and health sciences, Islets of Langerhans, Mice, 0302 clinical medicine, Endocrinology, Internal medicine, Insulin-Secreting Cells, medicine, Animals, Humans, Peptide YY, media_common, chemistry.chemical_classification, geography, geography.geographical_feature_category, biology, Chemistry, Lamprey, digestive, oral, and skin physiology, Appetite, biology.organism_classification, Islet, Receptors, Neuropeptide Y, 030104 developmental biology, Anorectic, human activities, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe091b2a19f0f1e514b5a727b85c269Test
https://pubmed.ncbi.nlm.nih.gov/32777442Test -
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المؤلفون: Marleen Groenen, Simon J. Mountford, Mengjie Liu, Philip E. Thompson, Nicholas D. Holliday, Rachel R. Richardson, Stephen J. Briddon
المصدر: Journal of medicinal chemistry. 63(10)
مصطلحات موضوعية: Stereochemistry, Dimer, Peptide, CHO Cells, Peptides, Cyclic, chemistry.chemical_compound, Cricetulus, Cricetinae, Drug Discovery, Animals, Humans, Receptor, chemistry.chemical_classification, biology, Dose-Response Relationship, Drug, Chinese hamster ovary cell, Neuropeptides, Antagonist, biology.organism_classification, Receptors, Neuropeptide Y, Ring size, HEK293 Cells, chemistry, Molecular Medicine, Protein Multimerization, Selectivity
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16598329f448b7f619db754ca8ac4cd0Test
https://pubmed.ncbi.nlm.nih.gov/32364733Test -
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المؤلفون: Steven L. Shipp, Guoqing Wang, Elizabeth R. Gilbert, Mark A. Cline, Yang Xiao
المصدر: Comparative biochemistry and physiology. Part A, Molecularintegrative physiology. 244
مصطلحات موضوعية: 0301 basic medicine, Physiology, Lipolysis, Subcutaneous Fat, Adipose tissue, Biology, Fatty Acids, Nonesterified, Biochemistry, Quail, 03 medical and health sciences, NEFA, Japan, biology.animal, Enhancer binding, Animals, RNA, Messenger, Molecular Biology, chemistry.chemical_classification, 030109 nutrition & dietetics, Coturnix japonica, Fatty acid, Fasting, Feeding Behavior, Neuropeptide Y receptor, biology.organism_classification, Receptors, Neuropeptide Y, 030104 developmental biology, chemistry, Animals, Newborn, CCAAT-Enhancer-Binding Proteins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e0745de5194204b90aa5e45f06d2deTest
https://pubmed.ncbi.nlm.nih.gov/32171800Test -
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المؤلفون: Tohru Mekata, Tomoya Kono, Kenji Mori, Takanori Ida, Mikiya Miyazato, Takahiro Sato, Jun Satoh, Morikatsu Yoshida
المصدر: General and Comparative Endocrinology. 246:321-330
مصطلحات موضوعية: 0301 basic medicine, Peptide, Biology, Transcriptome, 03 medical and health sciences, Endocrinology, Penaeidae, Gene expression, Animals, Drosophila Proteins, Tissue Distribution, Receptor, Gene, G protein-coupled receptor, chemistry.chemical_classification, Neuropeptides, biology.organism_classification, Molecular biology, Receptors, Neuropeptide Y, Shrimp, 030104 developmental biology, chemistry, Biochemistry, Drosophila, Animal Science and Zoology, Drosophila melanogaster, Peptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b89ecf92718a4e51e34f97049e8f3aeTest
https://doi.org/10.1016/j.ygcen.2017.01.008Test -
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المؤلفون: Rachel R. Richardson, Mengjie Liu, Simon J. Mountford, Lei Zhang, Philip E. Thompson, Matheus H. Tempone, Nicholas D. Holliday, Herbert Herzog
المصدر: Bioconjugate Chemistry. 27:2166-2175
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Peptide, Ligands, Binding, Competitive, 01 natural sciences, Partial agonist, 03 medical and health sciences, chemistry.chemical_compound, Humans, Neuropeptide Y, Amino Acid Sequence, Cyanine, Coloring Agents, Receptor, Peptide sequence, Pharmacology, chemistry.chemical_classification, Staining and Labeling, 010405 organic chemistry, Ligand, Organic Chemistry, Antagonist, Carbocyanines, Neuropeptide Y receptor, Peptide Fragments, Receptors, Neuropeptide Y, 0104 chemical sciences, HEK293 Cells, 030104 developmental biology, chemistry, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972bb0b302eedd9bc0fbc36b8584ec5bTest
https://doi.org/10.1021/acs.bioconjchem.6b00376Test