How novel combos could overcome resistance to targeted drugs in leukemia, solid tumors and more.

التفاصيل البيبلوغرافية
العنوان: How novel combos could overcome resistance to targeted drugs in leukemia, solid tumors and more.
المؤلفون: Weintraub, Arlene
المصدر: FierceBiotech; 12/21/2020, pN.PAG-N.PAG, 1p
مصطلحات موضوعية: DRUG resistance, COLON cancer, LEUKEMIA, TUMORS, MTOR inhibitors
مصطلحات جغرافية: CINCINNATI (Ohio)
الشركة/الكيان: UNIVERSITY of California, Los Angeles, NATIONAL Academy of Sciences (U.S.)
مستخلص: Researchers at Cincinnati Children's and UCLA have preclinical evidence suggesting that combining mTOR or BRAF inhibitors with other targeted treatments could overcome resistance in several cancers. The findings could guide research aimed at finding new treatments for leukemia and melanoma, as well as lung, pancreatic and colon cancer. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index