دورية أكاديمية
Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas
| العنوان: | Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas |
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| المؤلفون: | İrfan Cicin, Tahsin Özatlı, Esma Türkmen, Türkan Özturk, Melike Özçelik, Devrim Çabuk, Ayşe Gökdurnalı, Özlem Balvan, Yaşar Yıldız, Metin Şeker, Nuriye Özdemir, Burcu Yapar, Özgür Tanrıverdi, Yusuf Günaydin, Serkan Menekşe, Berna Öksüzoğlu, Asude Aksoy, Bülent Erdogan, M Bekir Hacıoglu, Erkan Arpaci, Alper Sevinç |
| المساهمون: | Sivas Cumhuriyet Üniversitesi |
| سنة النشر: | 2016 |
| المجموعة: | Sivas Cumhuriyet University Institutional Repository |
| مصطلحات موضوعية: | Cerrahi |
| الوصف: | Background: Prognostic factors and the standard treatment approach for gynaecological carcinosarco-mas have not yet been clearly defined. Although car-cinosarcomas are more aggressive than pure epithelial tumours, they are treated similarly. Serous/clear cell and endometrioid components may be predictive fac-tors for the efficacy of adjuvant chemotherapy (CT) or radiotherapy (RT) or RT in patients with uterine and ovarian carcinosarcomas. Heterologous carcino-sarcomas may benefit more from adjuvant CT.Aims: We aimed to define the prognostic and predic-tive factors associated with treatment options in ovar-ian (OCS) and uterine carcinosarcoma (UCS).Study Design: Retrospective cross-sectional studyMethods: We retrospectively reviewed the medical re-cords of patients with ovarian and uterine carcinosar-coma from 2000 to 2013, and 127 women were includ-ed in this study (24 ovarian and 103 uterine). Patients admitted to seventeen oncology centres in Turkey be-tween 2000 and December 2013 with a histologically proven diagnosis of uterine carcinosarcoma with FIGO 2009 stage I-III and patients with sufficient data ob-tained from well-kept medical records were included in this study. Stage IV tumours were excluded. The pa-tient records were retrospectively reviewed. Data from 104 patients were evaluated for this study.Results: Age (>=70 years) was a poor prognostic factor for UCS (p=0.036). Pelvic±para aortic lymph node dis-section did not affect overall survival (OS) (p=0.35). Macroscopic residual disease was related with OS (p<0.01). The median OS was significantly longer in stage I-II patients than stage III patients (p=0.03). Adjuvant treatment improved OS (p=0.013). Adju-vant radiotherapy tended to increase the median OS ; Background: Prognostic factors and the standard treatment approach for gynaecological carcinosarco-mas have not yet been clearly defined. Although car-cinosarcomas are more aggressive than pure epithelial tumours, they are treated similarly. Serous/clear cell and endometrioid components may ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2146-3123 |
| العلاقة: | Balkan Medical Journal; Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı; http://www.trdizin.gov.tr/publication/paper/detail/TWpBME5UWXdNQT09Test; https://hdl.handle.net/20.500.12418/4231Test; 33; 524; 517 |
| الإتاحة: | https://doi.org/20.500.12418/4231Test https://hdl.handle.net/20.500.12418/4231Test http://www.trdizin.gov.tr/publication/paper/detail/TWpBME5UWXdNQT09Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.867079D7 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 21463123 |
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