التفاصيل البيبلوغرافية
| العنوان: |
Intraparenchymal intracranial pressure monitoring for hydrocephalus and cerebrospinal fluid disorders. |
| المؤلفون: |
Chari, Aswin, Dasgupta, Debayan, Smedley, Alexander, Craven, Claudia, Dyson, Edward, Matloob, Samir, Thompson, Simon, Thorne, Lewis, Toma, Ahmed, Watkins, Laurence |
| المصدر: |
Acta Neurochirurgica; Oct2017, Vol. 159 Issue 10, p1967-1978, 12p |
| مصطلحات موضوعية: |
INTRACRANIAL pressure, HYDROCEPHALUS, CEREBROSPINAL fluid, INTRACRANIAL hypertension, CEREBROSPINAL fluid shunts, DIAGNOSIS |
| مستخلص: |
Background: Elective intraparenchymal intracranial pressure (ICP) monitoring is useful for the diagnosis and treatment of hydrocephalus and cerebrospinal fluid (CSF) disorders. This retrospective study analyzes median ICP and pulse amplitude (PA) recordings in neurosurgically naïve patients undergoing elective ICP monitoring for suspected CSF disorders. Methods: Retrospective review of prospectively collated database of neurosurgically naïve patients undergoing elective ICP monitoring for suspected hydrocephalus and CSF disorders. Following extraction of the median ICP and PA values (separated into all, day and night time recordings), principal component analysis (PCA) was performed to identify the principal factors determining the spread of the data. Exploratory comparisons and correlations of ICP and PA values were explored, including by post hoc diagnostic groupings and age. Results: A total of 198 patients were identified in six distinct diagnostic groups ( n = 21-47 in each). The PCA suggested that there were two main factors accounting for the spread in the data, with 61.4% of the variance determined largely by the PA and 33.0% by the ICP recordings. Exploratory comparisons of PA and ICP between the diagnostic groups showed significant differences between the groups. Specifically, significant differences were observed in PA between a group managed conservatively and the Chiari/syrinx, IIH, and NPH/LOVA groups and in the ICP between the conservatively managed group and high-pressure, IIH, and low-pressure groups. Correlations between ICP and PA revealed some interesting trends in the different diagnostic groups and correlations between ICP, PA, and age revealed a decreasing ICP and increasing PA with age. Conclusions: This study provides insights into hydrodynamic disturbances in different diagnostic groups of patients with CSF hydrodynamic disorders. It highlights the utility of analyzing both median PA and ICP recordings, stratified into day and night time recordings. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
