دورية أكاديمية
Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
| العنوان: | Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2) |
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| المؤلفون: | Towns, Clodagh, Richer, Madeleine, Jasaityte, Simona, Stafford, Eleanor J., Joubert, Julie, Antar, Tarek, Martinez-Carrasco, Alejandro, Makarious, Mary B., Casey, Bradford, Vitale, Dan, Levine, Kristin, Leonard, Hampton, Pantazis, Caroline B., Screven, Laurel A., Hernandez, Dena G., Wegel, Claire E., Solle, Justin, Nalls, Mike A., Blauwendraat, Cornelis, Singleton, Andrew B., Tan, Manuela M. X., Iwaki, Hirotaka, Morris, Huw R., Foo, Jia Nee |
| المساهمون: | Lee Kong Chian School of Medicine (LKCMedicine) |
| سنة النشر: | 2023 |
| المجموعة: | DR-NTU (Digital Repository at Nanyang Technological University, Singapore) |
| مصطلحات موضوعية: | Medicine, Health and Life Sciences, Cerebrospinal Fluid, Parkinson Disease |
| الوصف: | The Global Parkinson's Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia. ; Published version ; This research is supported by the Aligning Science Across Parkinson’s Initiative, the Intramural Research Program, National Institute on Aging, National Institutes of Health, Department of Health and Human Services, project ZO1 AG000949, and the Michael J. Fox Foundation for Parkinson’s Research. Data used in the preparation of this article were obtained from Global Parkinson’s Genetics Program (GP2). GP2 is funded by the Aligning Science Across Parkinson’s (ASAP) initiative and implemented by The Michael J. Fox Foundation for Parkinson’s Research (https://gp2.orgTest). |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2373-8057 |
| العلاقة: | NPJ Parkinson's Disease; Towns, C., Richer, M., Jasaityte, S., Stafford, E. J., Joubert, J., Antar, T., Martinez-Carrasco, A., Makarious, M. B., Casey, B., Vitale, D., Levine, K., Leonard, H., Pantazis, C. B., Screven, L. A., Hernandez, D. G., Wegel, C. E., Solle, J., Nalls, M. A., Blauwendraat, C., .Foo, J. N. (2023). Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2). NPJ Parkinson's Disease, 9(1), 131-. https://dx.doi.org/10.1038/s41531-023-00533-wTest; https://hdl.handle.net/10356/173527Test; 2-s2.0-85170643330; 131 |
| DOI: | 10.1038/s41531-023-00533-w |
| الإتاحة: | https://doi.org/10.1038/s41531-023-00533-wTest https://hdl.handle.net/10356/173527Test |
| حقوق: | © 2023 The Author(s). Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http:// creativecommons.org/licenses/by/4.0/. |
| رقم الانضمام: | edsbas.DA52A4B1 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 23738057 |
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| DOI: | 10.1038/s41531-023-00533-w |