دورية أكاديمية

Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways.

التفاصيل البيبلوغرافية
العنوان: Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways.
المؤلفون: Kilic, Ertugrul, Kilic, Ülkan, Soliz, Jorge, Bassetti, Claudio L., Gassmann, Max, Hermann, Dirk M.
المصدر: FASEB Journal; Dec2005, Vol. 19 Issue 14, p2026-2028, 3p, 1 Color Photograph, 1 Diagram, 2 Graphs
مصطلحات موضوعية: ERYTHROPOIETIN, CEREBRAL ischemia, LABORATORY mice, TRANSGENIC mice, HEMATOPOIETIC growth factors
مستخلص: The article presents a study which tested erythropoietin's (Epo) neuroprotective efficacy after focal cerebral ischemia in a transgenic mouse line and elucidated the signaling mechanisms responsible for Epo's neuroprotective function. Principal findings are given. Conclusions and significance of the study are discussed.
قاعدة البيانات: Complementary Index
الوصف
تدمد:08926638
DOI:10.1096/fj.05-3941fje