المؤلفون: Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S

المساهمون: Hubrecht Institute with UMC

مصطلحات موضوعية: Antineoplastic Agents/pharmacology, Cell Proliferation, Cells, Cultured, Crystallography, X-Ray, Drug Contamination, Glycine/analogs & derivatives, Humans, Microtubules/drug effects, Mutation, Neoplasms/drug therapy, Pharmaceutical Preparations/chemistry, Protein Conformation, Sulfones/pharmacology, Tubulin/chemistry, microtubules, CRISPRi, chemical genetics, rigosertib, CRISPRa, drug mechanism of action, drug target identification, Molecular Biology, Cell Biology, Research Support, Non-U.S. Gov't, Journal Article, N.I.H., Extramural

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/442183Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/442183Test

المؤلفون: Canela, María-Dolores, Noppen, Sam, Bueno, Oskía, Prota, Andrea E., Bargsten, Katja, Sáez-Calvo, Gonzalo, Jimeno, María-Luisa, Benkheil, Mohammed, Ribatti, Domenico, Velázquez, Sonsoles, Camarasa, María-José, Fernando Díaz, J., Steinmetz, Michel O., Priego, Eva-María, Pérez-Pérez, María-Jesús, Liekens, Sandra

المساهمون: Canela, María-Dolore, Noppen, Sam, Bueno, Oskía, Prota, Andrea E., Bargsten, Katja, Sáez-Calvo, Gonzalo, Jimeno, María-Luisa, Benkheil, Mohammed, Ribatti, Domenico, Velázquez, Sonsole, Camarasa, María-José, Fernando Díaz, J., Steinmetz, Michel O., Priego, Eva-María, Pérez-Pérez, María-Jesú, Liekens, Sandra

مصطلحات موضوعية: Cancer, Drug research, Tubulin, Vascular-disrupting, Angiogenesis Inhibitor, Animal, Antineoplastic Agent, Apoptosi, Benzodioxole, Binding Site, Breast Neoplasm, Cell Movement, Cell Proliferation, Cells, Cultured, Chalcone, Crystallography, X-Ray, Dipeptide, Endothelium, Vascular, Female, Human, Melanoma, Experimental, Mice, SCID, Neovascularization, Pathologic, Prodrug

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27224920; volume:8; issue:9; firstpage:14325; lastpage:14342; numberofpages:18; journal:ONCOTARGET; http://hdl.handle.net/11586/228005Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85014070318; http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=download&pathTest[]=9527&path[]=29775

الإتاحة: https://doi.org/10.18632/oncotarget.9527Test
http://hdl.handle.net/11586/228005Test
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=download&pathTest[]=9527&path[]=29775

المؤلفون: Trigili, Chiara, Barasoain, Isabel, Sánchez-Murcia, Pedro A., Bargsten, Katja, Redondo-Horcajo, Mariano, Nogales, Aurora, Gardner, Nicola M., Meyer, Arndt, Naylor, Guy J., Gomez-Rubio, Elena, Gago, Federico, Steinmetz, Michel O., Paterson, Ian, Prota, Andrea E., Díaz, José Fernando

المساهمون: Ministerio de Economía y Competitividad (España), Comunidad de Madrid, Swiss National Science Foundation, AstraZeneca

مصطلحات موضوعية: Ligand, Antineoplastic agents, Cells, Noncovalent interactions, Screening assays

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BIO2013-42984-R; http://dx.doi.org/10.1021/acsomega.6b00317Test; Sí; ACS Omega 1(6) 1192- 1204 (2016); http://hdl.handle.net/10261/251270Test; http://dx.doi.org/10.13039/501100003329Test; http://dx.doi.org/10.13039/100004325Test; http://dx.doi.org/10.13039/100012818Test

الإتاحة: https://doi.org/10.1021/acsomega.6b00317Test
https://doi.org/10.13039/501100003329Test
https://doi.org/10.13039/100004325Test
https://doi.org/10.13039/100012818Test
http://hdl.handle.net/10261/251270Test

المؤلفون: Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S, Sub Cell Biology, Celbiologie

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Sub Cell Biology, Celbiologie

المصدر: Molecular Cell
Molecular Cell, 79(1), 191. Cell Press
Molecular Cell, 79(1), 191-198.e3. Cell Press

مصطلحات موضوعية: Protein Conformation, Mutant, Cell, medicine.disease_cause, Crystallography, X-Ray, Microtubules, 0302 clinical medicine, Tubulin, Neoplasms, Sulfones, Cells, Cultured, Glycine/analogs & derivatives, Mutation, 0303 health sciences, Cultured, Crystallography, biology, Chemistry, rigosertib, Rigosertib, drug mechanism of action, 3. Good health, Cell biology, medicine.anatomical_structure, chemical genetics, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Pharmaceutical Preparations/chemistry, Drug Contamination, Antineoplastic Agents/pharmacology, Cells, Glycine, Antineoplastic Agents, Article, 03 medical and health sciences, CRISPRa, Tubulin/chemistry, Microtubule, medicine, Humans, Binding site, Molecular Biology, 030304 developmental biology, Cell Proliferation, drug target identification, CRISPRi, Cell Biology, In vitro, Neoplasms/drug therapy, Sulfones/pharmacology, Cancer cell, X-Ray, biology.protein, Microtubules/drug effects, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e69dbc0caaaee2c44b7494dfd72fa4Test
https://pubmed.ncbi.nlm.nih.gov/32619469Test

المؤلفون: Prota, Andrea E., Campbell, Jacquelyn A., Schelling, Pierre, Forrest, J. Craig, Watson, Melissa J., Peters, Timothy R., Aurrand-Lions, Michel, Imhof, Beat A., Dermody, Terence S., Stehle, Thilo

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 4/29/2003, Vol. 100 Issue 9, p5366. 6p. 3 Color Photographs, 8 Diagrams, 1 Chart, 3 Graphs.

مصطلحات موضوعية: *REOVIRUSES, *CELLS, *ADENOVIRUSES