العنوان البديل: Regulating mechanism of miR-7 in sensitivity of colorectal cancer cells to 5-fluorouracil. (English)

المؤلفون: 张岩, 田素礼, 周勇旭, 刘昶

المصدر: Practical Oncology Journal; 2023, Vol. 37 Issue 4, p320-328, 9p

مصطلحات موضوعية: REVERSE transcriptase polymerase chain reaction, FLOW cytometry, PROTEINS, CELL culture, WESTERN immunoblotting, MICRORNA, APOPTOSIS, RNA, CELL physiology, MTOR inhibitors, COLORECTAL cancer, FLUOROURACIL, GENE expression, TREATMENT effectiveness, CELLULAR signal transduction, CELL survival, CELL proliferation, TRANSFERASES, CELL lines, COMBINED modality therapy, DRUG resistance in cancer cells, CASPASES

المؤلفون: Chen, Mei, Tan, An-hui, Li, Jing

المصدر: Nutrition & Cancer; 2023, Vol. 75 Issue 2, p726-733, 8p, 1 Diagram, 6 Graphs

مصطلحات موضوعية: DISEASE progression, IN vitro studies, GLUTATHIONE, WESTERN immunoblotting, CURCUMIN, MTOR inhibitors, COLORECTAL cancer, CELLULAR signal transduction, MALONDIALDEHYDE, CELL survival, CELL proliferation, DESCRIPTIVE statistics, REACTIVE oxygen species

المؤلفون: Mondielli, Gregoire, Mougel, Gregory, Darriet, Florent, Roche, Catherine, Querdray, Adeline, Lisbonis, Christophe, Appay, Romain, Dufour, Henry, Chinot, Olivier, Graillon, Thomas, Barlier, Anne

المصدر: Cancers; Sep2022, Vol. 14 Issue 18, pN.PAG-N.PAG, 18p

مصطلحات موضوعية: PROTEIN metabolism, IN vitro studies, STATISTICAL significance, STATISTICS, CARCINOGENESIS, WESTERN immunoblotting, MTOR inhibitors, SIGNAL peptides, APOPTOSIS, MANN Whitney U Test, CELLULAR signal transduction, CELL survival, MENINGIOMA, TRANSFERASES, EVEROLIMUS, GENOMICS, CELL proliferation, CHI-squared test, DESCRIPTIVE statistics, MITOGEN-activated protein kinases, CELL lines, DATA analysis, DATA analysis software

المؤلفون: Song, Tao, Zhang, Huazhou

المصدر: Breast Journal; 8/28/2022, Vol. 2022, p1-13, 13p

مصطلحات موضوعية: XENOGRAFTS, CELL culture, RNA-binding proteins, WESTERN immunoblotting, METASTASIS, MTOR inhibitors, APOPTOSIS, HEALTH outcome assessment, CELLULAR signal transduction, CELL survival, CELL motility, CISPLATIN, CELL proliferation, DESCRIPTIVE statistics, POLYMERASE chain reaction, CELL lines, BREAST tumors, DRUG resistance in cancer cells, PHARMACODYNAMICS

المؤلفون: Maksudul Alam, Caden O Maxwell, Janmaris Marin Fermin, Tara Moore-Medlin, Cherie-Ann O. Nathan, Chaning Burnett, Alok R. Khandelwal, Patrick T. Spiller, Xiaohua Rong

المصدر: Molecular Carcinogenesis. 61:33-44

مصطلحات موضوعية: Cancer Research, Programmed cell death, Cell Survival, Autophagic Cell Death, mTORC1, Biology, Mice, Cell Line, Tumor, medicine, Animals, Autophagy-Related Protein-1 Homolog, Humans, Everolimus, Viability assay, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Sirolimus, Squamous Cell Carcinoma of Head and Neck, Autophagy, Intracellular Signaling Peptides and Proteins, MTOR Inhibitors, medicine.disease, Xenograft Model Antitumor Assays, Head and neck squamous-cell carcinoma, Gene Expression Regulation, Neoplastic, Head and Neck Neoplasms, Apoptosis, Mutation, Cancer research, Tumor Suppressor Protein p53

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fcfe1f81b778488448584ee326c106Test
https://doi.org/10.1002/mc.23357Test

المؤلفون: Seyed Mohammad Abedi, Samaneh Vaseghi, Nasrin Abbasi Gharibkandi, Alireza Mardanshahi, Sajjad Molavipordanjani

المصدر: Molecular Biology Reports. 48:1-14

مصطلحات موضوعية: Cell Survival, medicine.medical_treatment, Apoptosis, Radiation Tolerance, Phosphatidylinositol 3-Kinases, Cell Line, Tumor, Neoplasms, Autophagy, Genetics, medicine, Humans, Radiosensitivity, Protein Kinase Inhibitors, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Cell growth, Akt/PKB signaling pathway, business.industry, TOR Serine-Threonine Kinases, Cell Cycle, Cancer, MTOR Inhibitors, General Medicine, medicine.disease, Radiation therapy, Cancer research, business, Proto-Oncogene Proteins c-akt, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fdb87979d16875fbb742eee534b74bTest
https://doi.org/10.1007/s11033-021-06607-3Test

المؤلفون: Marzanna Cechowska-Pasko, Ewa Jabłońska, Wioletta Ratajczak-Wrona, Rafał Krętowski, Wioleta Justyna Omeljaniuk

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 11511, p 11511 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21

مصطلحات موضوعية: GDC-0980, Cell Survival, QH301-705.5, CHOP, Article, Catalysis, Metastasis, Inorganic Chemistry, Cell Line, Tumor, medicine, Humans, Physical and Theoretical Chemistry, Biology (General), Cytotoxicity, Molecular Biology, Protein kinase B, QD1-999, Spectroscopy, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Chemistry, Brain Neoplasms, Organic Chemistry, Autophagosomes, apoptosis, glioblastoma, Cancer, General Medicine, MTOR Inhibitors, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Endoplasmic Reticulum Stress, dual PI3K/mTOR inhibitor, Computer Science Applications, Pyrimidines, Apoptosis, Cell culture, Cancer research, apitolisib, Drug Screening Assays, Antitumor, Metabolic Networks and Pathways

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2276301b12f4db2a038b16ea5030b6b3Test
https://www.mdpi.com/1422-0067/22/21/11511Test

المؤلفون: Takayoshi Suzuki, Gabrielle Gray, Rajeshwar Rao Tekmal, Yi He, Srinath Palakurthi, Sureshkumar Mulampurath Achuthan Pillai, Prabhakar Pitta Venkata, Zhao Lai, Junhao Liu, Edward R. Kost, Salvador Alejo, Suryavathi Viswanadhapalli, Ilanna Loeffel, Gangadhara R. Sareddy, Yi Zou, Bridgitte E. Palacios, Ratna K. Vadlamudi, Uday P. Pratap, Yihong Chen

المصدر: Cancer letters. 524

مصطلحات موضوعية: Male, Cancer Research, Cell Survival, medicine.medical_treatment, Apoptosis, mTORC2, Targeted therapy, Mice, Cell Movement, medicine, Animals, Humans, Viability assay, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Histone Demethylases, Sirolimus, Chemistry, TOR Serine-Threonine Kinases, MTOR Inhibitors, Xenograft Model Antitumor Assays, Endometrial Neoplasms, Gene Expression Regulation, Neoplastic, Oncology, Cancer research, Female, Drug Screening Assays, Antitumor, Chromatin immunoprecipitation, Ex vivo, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ad2d9424beea8ece843b299524d4ecTest
https://pubmed.ncbi.nlm.nih.gov/34673129Test

المؤلفون: Marc R. Mansour, Alla Berezovskaya, E. Elizabeth Patton, Chang-Bin Jing, Julia Etchin, Charles K. Kaufman, Mark W. Zimmerman, Scott J. Rodig, Megan W. Martel, A. Thomas Look, Leonard I. Zon, Hillary M. Layden, Grace Thurston, Shuning He, Ellen van Rooijen

المصدر: Oncogene
He, S, Zimmerman, M W, Layden, H M, Berezovskaya, A, Etchin, J, Martel, M W, Thurston, G, Jing, C-B, van Rooijen, E, Kaufman, C K, Rodig, S J, Zon, L I, Patton, E E, Mansour, M R & Look, A T 2021, ' Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss ', Oncogene . https://doi.org/10.1038/s41388-021-01926-yTest

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Programmed cell death, Cell Survival, Thiophenes, Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Loss of Function Mutation, Cell Line, Tumor, Genetics, medicine, PTEN, Animals, Humans, Everolimus, Cancer models, Molecular Biology, neoplasms, Melanoma, PI3K/AKT/mTOR pathway, Zebrafish, Cell Proliferation, Sirolimus, Sulfonamides, Neurofibromin 1, Venetoclax, PTEN Phosphohydrolase, Drug Synergism, MTOR Inhibitors, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Xenograft Model Antitumor Assays, Temsirolimus, 030104 developmental biology, Pyrimidines, chemistry, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Myeloid Cell Leukemia Sequence 1 Protein, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9204b7f93b2e55dccf004f4c12d0f189Test
https://pubmed.ncbi.nlm.nih.gov/34331013Test

المؤلفون: Kuan-Wei Lee, Max K. Leong, Ching-Feng Weng, Varadharajan Thiyagarajan

المصدر: Journal of Biomolecular Structure and Dynamics. 36:4220-4234

مصطلحات موضوعية: Male, 0301 basic medicine, Curcumin, Cell Survival, In silico, Biology, Rats, Sprague-Dawley, Serine, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Hepatic Stellate Cells, Animals, Phosphorylation, Threonine, Protein Kinase Inhibitors, Molecular Biology, Cells, Cultured, PI3K/AKT/mTOR pathway, Cell Proliferation, Sirolimus, Dose-Response Relationship, Drug, Kinase, Cell growth, TOR Serine-Threonine Kinases, Ribosomal Protein S6 Kinases, 70-kDa, General Medicine, Discovery and development of mTOR inhibitors, Cell biology, Molecular Docking Simulation, 030104 developmental biology, 030220 oncology & carcinogenesis, Hepatic stellate cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0d95f4ed856b4dbefe3bd369c0c9acTest
https://doi.org/10.1080/07391102.2017.1411295Test