المؤلفون: Sakamoto, Y., Sato, M., Sato, Y., Harada, A., Suzuki, T., Goto, C., Tamura, K., Toyooka, K., Kimura, Hiroshi, Ohkawa, Y., Hara-Nishimura, I., Takagi, S., Matsunaga, S.

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Lamina, genetic structures, Arabidopsis, General Physics and Astronomy, 01 natural sciences, Gene Expression Regulation, Plant, Gene expression, RNA-Seq, lcsh:Science, In Situ Hybridization, Fluorescence, Plant Proteins, Regulation of gene expression, Multidisciplinary, Arabidopsis Proteins/genetics/metabolism, biology, Nuclear Proteins, Copper/*metabolism, Nuclear Proteins/genetics/metabolism, Chromatin, Cell biology, Nuclear lamina, Mutation/genetics, Science, Locus (genetics), Article, General Biochemistry, Genetics and Molecular Biology, Chromatin/metabolism, 03 medical and health sciences, Developmental biology, Arabidopsis/genetics, Gene, Nuclear Lamina/genetics/metabolism/ultrastructure, Cell Nucleus, Nuclear Lamina, Arabidopsis Proteins, General Chemistry, biology.organism_classification, 030104 developmental biology, Cell Nucleus/metabolism, Mutation, lcsh:Q, Plant Proteins/genetics/metabolism, Plant sciences, Copper, 010606 plant biology & botany

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949272ba3b3b82233de1724517e6100fTest
https://doaj.org/article/c86f370d5995440ea4edd12a155f947bTest

المؤلفون: Dreesen, Oliver

المصدر: Biochemical Society Transactions

مصطلحات موضوعية: DNA Replication, Senescence, Aging, Cytoplasm, congenital, hereditary, and neonatal diseases and abnormalities, senescence, DNA Repair, DNA repair, Biology, Biochemistry, Molecular Bases of Health & Disease, LMNA, Mice, 03 medical and health sciences, Progeria, 0302 clinical medicine, Intermediate Filament Proteins, Protein Domains, medicine, Animals, Humans, DNA, Chromosomes & Chromosomal Structure, Review Articles, Cellular Senescence, lamin A, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Nuclear Lamina, integumentary system, Gene Expression Profiling, Nuclear Proteins, Aging, Premature, Lamin Type A, Progerin, medicine.disease, Chromatin, Cell biology, Phenotype, Mutation, Nuclear lamina, 030217 neurology & neurosurgery, Lamin, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f564c38951688975c2cd9b9d5194fb4Test
https://doi.org/10.1042/bst20190882Test

المؤلفون: Manindra Bera, Kaushik Sengupta

المصدر: Nucleus, Vol 11, Iss 1, Pp 99-110 (2020)
Nucleus
article-version (VoR) Version of Record

مصطلحات موضوعية: intermediate filaments, chromosomal positioning, lcsh:QH426-470, inter/intra-chromosomal contacts, Review, macromolecular substances, myosin, Biology, LMNA, 03 medical and health sciences, Animals, Humans, Inner membrane, Chromosome Positioning, lcsh:QH573-671, Intermediate filament, loop-clusters, Actin, 030304 developmental biology, Cell Nucleus, nuclear lamins, 0303 health sciences, Nuclear Lamina, Nucleoplasm, lcsh:Cytology, laminopathies, 030302 biochemistry & molecular biology, Cell Biology, Lamin Type A, Cell biology, lcsh:Genetics, Gene Expression Regulation, Mutation, Nuclear lamina, actin, Lamin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f292df6757d2232340d9473f74c65a6aTest
https://doaj.org/article/ac2901bd281a46a98db0e33949f53240Test

المؤلفون: Silvia Ortega-Gutiérrez, Beatriz Marcos-Ramiro, Jon Macicior

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7190, p 7190 (2021)

مصطلحات موضوعية: 0301 basic medicine, Aging, Pyridines, Review, medicine.disease_cause, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Lonafarnib, Biology (General), Hutchinson–Gilford progeria syndrome (HGPS), Spectroscopy, Cellular Senescence, Skin, Progeria, Mutation, integumentary system, rare diseases, Aging, Premature, General Medicine, Progerin, Lamin Type A, Computer Science Applications, Chemistry, Phenotype, 030220 oncology & carcinogenesis, Nuclear lamina, congenital, hereditary, and neonatal diseases and abnormalities, QH301-705.5, Context (language use), Biology, Catalysis, Inorganic Chemistry, Small Molecule Libraries, 03 medical and health sciences, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, lamin A, Cell Nucleus, Nuclear Lamina, Point mutation, Organic Chemistry, Laminopathies, Química orgánica, nutritional and metabolic diseases, progeria, Fibroblasts, medicine.disease, 030104 developmental biology, chemistry, progerin, Cancer research, Lamin

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb1b7093f85929d11daee5c183d56dcTest
http://europepmc.org/articles/PMC8267806Test

المؤلفون: Robert A. Hegele, Rosettia Ho

المصدر: Clinical Genetics. 95:199-209

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Intermediate Filaments, Laminopathy, 030105 genetics & heredity, Biology, LMNA, 03 medical and health sciences, Genetics, medicine, Animals, Humans, Genetic Predisposition to Disease, Protein Interaction Domains and Motifs, Intermediate filament, Transcription factor, Alleles, Genetic Association Studies, Genetics (clinical), Cell Nucleus, Nuclear Lamina, integumentary system, medicine.disease, Phenotype, Chromatin, Lamins, 030104 developmental biology, Genetic Loci, Multigene Family, Mutation, embryonic structures, Nuclear lamina, Protein Processing, Post-Translational, Lamin, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9801a1c64075def1c8dfe51d224472bTest
https://doi.org/10.1111/cge.13455Test

المؤلفون: Stephen G. Young, Paul Kim, Amy C. Rowat, Patrick J. Heizer, Thomas A. Weston, Loren G. Fong, Navjot Kaur Gill, Natalie Y. Chen, Jared L.-C. Fong, Yiping Tu

المصدر: JCI Insight

مصطلحات موضوعية: Programmed cell death, congenital, hereditary, and neonatal diseases and abnormalities, Nuclear Envelope, Myocytes, Smooth Muscle, Mice, Transgenic, Mouse models, Muscle, Smooth, Vascular, Mice, Progeria, Vascular Biology, medicine.artery, medicine, Animals, Humans, Nuclear membrane, Aorta, integumentary system, Lamin Type B, Chemistry, General Medicine, medicine.disease, Progerin, Lamin Type A, Cardiovascular disease, Cell biology, Cell nucleus, Disease Models, Animal, medicine.anatomical_structure, Mutation, cardiovascular system, Nuclear lamina, Lamin, Research Article, Genetic diseases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca3024b2a09029014688642c5c36585Test
https://pubmed.ncbi.nlm.nih.gov/34423791Test

المؤلفون: Ivan P. Moskowitz, Kohta Ikegami, Stefano Secchia, Jason D. Lieb, Omar Almakki

المصدر: Dev Cell

مصطلحات موضوعية: Premature aging, Male, congenital, hereditary, and neonatal diseases and abnormalities, animal structures, Adolescent, Active Transport, Cell Nucleus, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, LMNA, Euchromatin, 03 medical and health sciences, 0302 clinical medicine, Progeria, Enhancer binding, Gene expression, medicine, Humans, Enhancer, Child, Molecular Biology, Cells, Cultured, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Binding Sites, Nuclear Lamina, integumentary system, Chemistry, 030302 biochemistry & molecular biology, nutritional and metabolic diseases, Cell Biology, Fibroblasts, medicine.disease, Lamin Type A, Cell biology, Histone, Enhancer Elements, Genetic, Mutation, embryonic structures, biology.protein, Nuclear lamina, 030217 neurology & neurosurgery, Lamin, Developmental Biology, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bc3a692936e97532b363ab8d8729beTest
https://europepmc.org/articles/PMC7201903Test/

المؤلفون: Oliver Dreesen, Mattheus Xing Rong Foo, Peh Fern Ong

المصدر: Journal of dermatological science. 96(2)

مصطلحات موضوعية: 0301 basic medicine, Premature aging, Senescence, DNA Replication, Aging, Contracture, DNA Repair, Dermatology, Disease, medicine.disease_cause, Bioinformatics, Biochemistry, Progeroid syndromes, 030207 dermatology & venereal diseases, 03 medical and health sciences, Mice, 0302 clinical medicine, Progeria, Heterochromatin, Medicine, Animals, Humans, Protein Precursors, Molecular Biology, Cellular Senescence, Cell Nucleus, Mutation, Nuclear Lamina, integumentary system, business.industry, Nuclear Proteins, Aging, Premature, Telomere, medicine.disease, Lamin Type A, Chromatin, 030104 developmental biology, Skin Abnormalities, Nuclear lamina, Werner Syndrome, business, Lamin, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7731b618260f585e519e48ac74a1ffTest
https://pubmed.ncbi.nlm.nih.gov/31727429Test

المؤلفون: Emanuela Scarano, Tomasz Stokowy, Tzung-Chien Hsieh, Florian Erger, Janine Altmueller, Christian Gilissen, Gunnar Houge, Trine Prescott, Christian Kubisch, Andrea Bevot, Maria Redfors, Davor Lessel, Laura Mazzanti, Torunn Fiskerstrand, Angelika Riess, Dejan Đukić, Peter Krawitz, Cecilie F. Rustad, Christian Netzer, Itamar Jobani, Felix Marbach

المصدر: American Journal of Human Genetics, 104, 4, pp. 749-757
American Journal of Human Genetics, 104, 749-757

مصطلحات موضوعية: Male, 0301 basic medicine, Adolescent, Computational biology, Biology, 03 medical and health sciences, Progeria, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, Artificial Intelligence, Report, Cell Line, Tumor, Genetics, medicine, Humans, Mass Screening, Supernumerary, Diagnosis, Computer-Assisted, Child, Gene, Genetics (clinical), Cell Nucleus, Genetic disorder, Membrane Proteins, Nuclear Proteins, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Syndrome, Geneticist, Fibroblasts, Prognosis, medicine.disease, Phenotype, 030104 developmental biology, Child, Preschool, Face, Mutation, Nuclear lamina, Intention tremor, medicine.symptom, Medical Informatics, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e979612262a8a27f16eb75d61eabdf7Test
https://doi.org/10.1016/j.ajhg.2019.02.021Test

المؤلفون: Tom Misteli, Leonid A. Serebryannyy

المصدر: Methods. 157:80-87

مصطلحات موضوعية: Premature aging, High throughput imaging, Proximity ligation assay, Computational biology, Article, General Biochemistry, Genetics and Molecular Biology, Protein–protein interaction, 03 medical and health sciences, Progeria, Protein Interaction Mapping, medicine, Humans, Protein Precursors, Nuclear protein, Molecular Biology, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Indirect immunofluorescence, Chemistry, 030302 biochemistry & molecular biology, Lamin Type A, medicine.disease, Highly sensitive, Mutation, Nuclear lamina

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674cadefb9fad406fd537ec0f36cdc3cTest
https://doi.org/10.1016/j.ymeth.2018.11.004Test