المؤلفون: Joshua L Justice, Laura A. Murray-Nerger, Pranav Rekapalli, Ileana M. Cristea, Josiah E. Hutton

المصدر: Nucleic Acids Research

مصطلحات موضوعية: DNA Repair, AcademicSubjects/SCI00010, DNA damage, DNA repair, Laminopathy, Herpesvirus 1, Human, Genome Integrity, Repair and Replication, Biology, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, Humans, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Nuclear Lamina, Lamin Type B, Lysine, Acetylation, DNA Repair Pathway, Cell cycle, medicine.disease, G1 Phase Cell Cycle Checkpoints, Chromatin, Cell biology, Nuclear lamina, Female, Tumor Suppressor p53-Binding Protein 1, 030217 neurology & neurosurgery, Lamin, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b63f1d82a6b6773e5d147542d34d8Test
https://doi.org/10.1093/nar/gkab019Test

المؤلفون: Laura A. Murray-Nerger, Ileana M. Cristea

المصدر: Trends Biochem Sci

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, animal structures, Biology, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, medicine, Humans, Muscular dystrophy, Intermediate filament, Molecular Biology, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Progeria, integumentary system, medicine.disease, Chromatin, Lamins, Cell biology, embryonic structures, biology.protein, Nuclear lamina, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, Lamin, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d23125ee92b860b37fba4ef76743f63Test
https://doi.org/10.1016/j.tibs.2021.05.007Test

المؤلفون: Dreesen, Oliver

المصدر: Biochemical Society Transactions

مصطلحات موضوعية: DNA Replication, Senescence, Aging, Cytoplasm, congenital, hereditary, and neonatal diseases and abnormalities, senescence, DNA Repair, DNA repair, Biology, Biochemistry, Molecular Bases of Health & Disease, LMNA, Mice, 03 medical and health sciences, Progeria, 0302 clinical medicine, Intermediate Filament Proteins, Protein Domains, medicine, Animals, Humans, DNA, Chromosomes & Chromosomal Structure, Review Articles, Cellular Senescence, lamin A, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Nuclear Lamina, integumentary system, Gene Expression Profiling, Nuclear Proteins, Aging, Premature, Lamin Type A, Progerin, medicine.disease, Chromatin, Cell biology, Phenotype, Mutation, Nuclear lamina, 030217 neurology & neurosurgery, Lamin, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f564c38951688975c2cd9b9d5194fb4Test
https://doi.org/10.1042/bst20190882Test

المؤلفون: Silvia Ortega-Gutiérrez, Beatriz Marcos-Ramiro, Jon Macicior

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7190, p 7190 (2021)

مصطلحات موضوعية: 0301 basic medicine, Aging, Pyridines, Review, medicine.disease_cause, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Lonafarnib, Biology (General), Hutchinson–Gilford progeria syndrome (HGPS), Spectroscopy, Cellular Senescence, Skin, Progeria, Mutation, integumentary system, rare diseases, Aging, Premature, General Medicine, Progerin, Lamin Type A, Computer Science Applications, Chemistry, Phenotype, 030220 oncology & carcinogenesis, Nuclear lamina, congenital, hereditary, and neonatal diseases and abnormalities, QH301-705.5, Context (language use), Biology, Catalysis, Inorganic Chemistry, Small Molecule Libraries, 03 medical and health sciences, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, lamin A, Cell Nucleus, Nuclear Lamina, Point mutation, Organic Chemistry, Laminopathies, Química orgánica, nutritional and metabolic diseases, progeria, Fibroblasts, medicine.disease, 030104 developmental biology, chemistry, progerin, Cancer research, Lamin

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb1b7093f85929d11daee5c183d56dcTest
http://europepmc.org/articles/PMC8267806Test

المؤلفون: Nemil Bhatt, Salome McAllen, Omar D. Johnson, Nicha Puangmalai, Urmi Sengupta, Michael G. Kharas, Rakez Kayed, Mauro Montalbano

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Cytoplasm, General Physics and Astronomy, RNA-binding protein, 02 engineering and technology, Protein aggregation, Mice, lcsh:Science, Cellular localization, Aged, 80 and over, Inclusion Bodies, Multidisciplinary, biology, Chemistry, Neurodegenerative diseases, RNA-Binding Proteins, Middle Aged, Alzheimer's disease, 021001 nanoscience & nanotechnology, Frontal Lobe, Cell biology, medicine.anatomical_structure, Nuclear lamina, Female, Tauopathy, 0210 nano-technology, Protein Binding, Science, Tau protein, Active Transport, Cell Nucleus, Mice, Transgenic, Nerve Tissue Proteins, tau Proteins, Molecular neuroscience, Article, General Biochemistry, Genetics and Molecular Biology, Protein Aggregates, 03 medical and health sciences, mental disorders, medicine, Animals, Humans, Aged, Cell Nucleus, Musashi2, General Chemistry, Chromatin Assembly and Disassembly, medicine.disease, digestive system diseases, Cellular neuroscience, Disease Models, Animal, Cell nucleus, HEK293 Cells, 030104 developmental biology, biology.protein, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c5b933ccf113f0ce6bfc72ceb7d508Test
https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af230Test

المؤلفون: Vashisth, Manasvita, Cho, Sangkyun, Irianto, Jerome, Xia, Yuntao, Wang, Mai, Hayes, Brandon, Wieland, Daniel, Wells, Rebecca, Jafarpour, Farshid, Liu, Andrea, Discher, Dennis E, Sub Cond-Matter Theory, Stat & Comp Phys, Theoretical Physics

المساهمون: Sub Cond-Matter Theory, Stat & Comp Phys, Theoretical Physics

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 118(48), 1. National Academy of Sciences

مصطلحات موضوعية: Proteomics, Cell Survival, Expression, Kaplan-Meier Estimate, Computational biology, Biology, Nucleus, Scaling, Mass Spectrometry, Mechanobiology, Extracellular matrix, Neoplasms, medicine, Humans, General, Gene, Transcription factor, Cell Proliferation, Cell Nucleus, Multidisciplinary, Lamin Type B, Gene Expression Profiling, Liver Neoplasms, Computational Biology, RNA, Cancer, DNA, Genomics, Oncogenes, Biological Sciences, Prognosis, medicine.disease, Fibrosis, Extracellular Matrix, Gene Expression Regulation, Neoplastic, Treatment Outcome, FOXM1, Nuclear lamina, Collagen, Stress, Mechanical, Transcriptome, Function (biology)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad253c028598464b67661742bdaf0fb3Test
https://doi.org/10.1073/pnas.2112940118Test

المؤلفون: Robert A. Hegele, Rosettia Ho

المصدر: Clinical Genetics. 95:199-209

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Intermediate Filaments, Laminopathy, 030105 genetics & heredity, Biology, LMNA, 03 medical and health sciences, Genetics, medicine, Animals, Humans, Genetic Predisposition to Disease, Protein Interaction Domains and Motifs, Intermediate filament, Transcription factor, Alleles, Genetic Association Studies, Genetics (clinical), Cell Nucleus, Nuclear Lamina, integumentary system, medicine.disease, Phenotype, Chromatin, Lamins, 030104 developmental biology, Genetic Loci, Multigene Family, Mutation, embryonic structures, Nuclear lamina, Protein Processing, Post-Translational, Lamin, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9801a1c64075def1c8dfe51d224472bTest
https://doi.org/10.1111/cge.13455Test

المؤلفون: Won Jing Wang, Ya-Hui Chi, Hong Chen Chen, Wei Syun Huang, Li Ru You, Ching Tung Chu, Jia Rong Fan

المصدر: EMBO Reports
EMBO Rep

مصطلحات موضوعية: ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Laminopathy, macromolecular substances, laminopathy, Biology, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Ciliogenesis, medicine, Genetics, lamin, Molecular Biology, Tissue homeostasis, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Nuclear Lamina, Nesprin, Chemistry, Cilium, cilia, Articles, Tau tubulin kinase 2, medicine.disease, Lamin Type A, Actins, Lamins, Addendum, Cell biology, ciliopathy, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Nuclear lamina, Cell Adhesion, Polarity & Cytoskeleton, 030217 neurology & neurosurgery, Lamin, ciliogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24946bf6bc725dbd0dcca0a25cccd3fbTest
http://europepmc.org/articles/PMC7534621Test

المؤلفون: Stephen G. Young, Paul Kim, Amy C. Rowat, Patrick J. Heizer, Thomas A. Weston, Loren G. Fong, Navjot Kaur Gill, Natalie Y. Chen, Jared L.-C. Fong, Yiping Tu

المصدر: JCI Insight

مصطلحات موضوعية: Programmed cell death, congenital, hereditary, and neonatal diseases and abnormalities, Nuclear Envelope, Myocytes, Smooth Muscle, Mice, Transgenic, Mouse models, Muscle, Smooth, Vascular, Mice, Progeria, Vascular Biology, medicine.artery, medicine, Animals, Humans, Nuclear membrane, Aorta, integumentary system, Lamin Type B, Chemistry, General Medicine, medicine.disease, Progerin, Lamin Type A, Cardiovascular disease, Cell biology, Cell nucleus, Disease Models, Animal, medicine.anatomical_structure, Mutation, cardiovascular system, Nuclear lamina, Lamin, Research Article, Genetic diseases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca3024b2a09029014688642c5c36585Test
https://pubmed.ncbi.nlm.nih.gov/34423791Test

المؤلفون: Ivan P. Moskowitz, Kohta Ikegami, Stefano Secchia, Jason D. Lieb, Omar Almakki

المصدر: Dev Cell

مصطلحات موضوعية: Premature aging, Male, congenital, hereditary, and neonatal diseases and abnormalities, animal structures, Adolescent, Active Transport, Cell Nucleus, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, LMNA, Euchromatin, 03 medical and health sciences, 0302 clinical medicine, Progeria, Enhancer binding, Gene expression, medicine, Humans, Enhancer, Child, Molecular Biology, Cells, Cultured, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Binding Sites, Nuclear Lamina, integumentary system, Chemistry, 030302 biochemistry & molecular biology, nutritional and metabolic diseases, Cell Biology, Fibroblasts, medicine.disease, Lamin Type A, Cell biology, Histone, Enhancer Elements, Genetic, Mutation, embryonic structures, biology.protein, Nuclear lamina, 030217 neurology & neurosurgery, Lamin, Developmental Biology, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bc3a692936e97532b363ab8d8729beTest
https://europepmc.org/articles/PMC7201903Test/