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1
المؤلفون: Jian Li, Kun-Liang Guan, Leonard Post, Andrei W. Konradi, Ying Feng, Xiao Peng, Fa-Xing Yu, Mingyue Ma, Tracy T. Tang
المصدر: Molecular Cancer Therapeutics. 20:986-998
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Hippo signaling pathway, Chemistry, Cell growth, Effector, In vitro, Merlin (protein), 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Palmitoylation, In vivo, 030220 oncology & carcinogenesis, Cancer research, Transcription factor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::509eed1cc6d2346fbb6bfc63d6fe0e58Test
https://doi.org/10.1158/1535-7163.mct-20-0717Test -
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المؤلفون: Zishuo Yu, Huirong Yang, Xizi Chen, Ning Gao, Yanhui Xu, Hai-Xin Yuan, Ningning Li, Kun-Liang Guan, Jiaxuan Cheng, Jiabei Li, Dan Ye
المصدر: Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, GTP', General Physics and Astronomy, mTORC1, GTPase, Tuberous Sclerosis Complex 1 Protein, Cell growth, Tuberous Sclerosis, Models, Cryoelectron microscopy, Small GTPase, Tumour-suppressor proteins, Multidisciplinary, biology, Chemistry, GTPase-Activating Proteins, medicine.anatomical_structure, RHEB, Protein Binding, Cell signalling, congenital, hereditary, and neonatal diseases and abnormalities, Science, 1.1 Normal biological development and functioning, Protein domain, General Biochemistry, Genetics and Molecular Biology, Article, Vaccine Related, 03 medical and health sciences, Rare Diseases, Protein Domains, Underpinning research, Biodefense, Tuberous Sclerosis Complex 2 Protein, medicine, Humans, 030102 biochemistry & molecular biology, Prevention, Molecular, General Chemistry, Brain Disorders, nervous system diseases, 030104 developmental biology, HEK293 Cells, biology.protein, Biophysics, Biocatalysis, Ras Homolog Enriched in Brain Protein, TSC1, TSC2, Protein Multimerization
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f5b1e548f704a6eddafca2d7a0d152Test
https://pubmed.ncbi.nlm.nih.gov/33436626Test -
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المؤلفون: Steven W. Plouffe, Audrey W. Hong, Kun-Liang Guan, Hai-Xin Yuan, Wantae Kim, Zhipeng Meng, Sungho Moon, Eek-hoon Jho
المصدر: EMBO reports. 18:72-86
مصطلحات موضوعية: 0301 basic medicine, Hippo signaling pathway, Osmotic shock, Kinase, Chemistry, Cell growth, Articles, Biochemistry, Cell biology, 03 medical and health sciences, Crosstalk (biology), 030104 developmental biology, Genetics, Phosphorylation, Molecular Biology, Nuclear localization sequence, Tissue homeostasis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0337d392c4ea53ece1a34c6f738c522dTest
https://doi.org/10.15252/embr.201642681Test -
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المؤلفون: Zhen Wang, Xin Zhou, Yi Ping Sun, Fulong Li, Yue Xiong, Hai Xin Yuan, Xu Feng, Meng Tian Li, Ying Yu, Kun-Liang Guan, Zhipeng Meng, Peng Liu
المصدر: Journal of Biological Chemistry. 291:18947-18958
مصطلحات موضوعية: 0301 basic medicine, Vascular smooth muscle, Myocytes, Smooth Muscle, Cell, 030204 cardiovascular system & hematology, GTP-Binding Protein alpha Subunits, G12-G13, Biochemistry, Muscle, Smooth, Vascular, Receptors, Thromboxane A2, Prostaglandin H2, Thromboxane A2, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Movement, medicine, Humans, Receptor, Molecular Biology, Adaptor Proteins, Signal Transducing, Cell Proliferation, Hippo signaling pathway, Cell growth, Intracellular Signaling Peptides and Proteins, YAP-Signaling Proteins, Cell migration, Cell Biology, Bridged Bicyclo Compounds, Heterocyclic, Phosphoproteins, Actin cytoskeleton, Cell biology, 030104 developmental biology, medicine.anatomical_structure, chemistry, Gene Knockdown Techniques, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Fatty Acids, Unsaturated, Trans-Activators, HeLa Cells, Signal Transduction, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215fc08f6a0314506c331b8dc5ebc67dTest
https://doi.org/10.1074/jbc.m116.739722Test -
5
المؤلفون: Mingjie Zhang, Zhou Yang, Zeyang Ji, Zhijie Lin, Kun-Liang Guan, Ruiling Xie
المصدر: eLife
eLife, Vol 8 (2019)مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Structural Biology and Molecular Biophysics, LATS, Mice, 0302 clinical medicine, Cell polarity, Protein Interaction Maps, Biology (General), KIBRA, 0303 health sciences, biology, Chemistry, General Neuroscience, Brain, Cell Polarity, General Medicine, Cell cycle, Cell biology, Protein Transport, Hippo signaling, 030220 oncology & carcinogenesis, Medicine, YAP, Synaptic signaling, Protein Binding, Research Article, WW domain tandem, QH301-705.5, Polarity (physics), Science, MAGI, DNA-binding protein, General Biochemistry, Genetics and Molecular Biology, WW Domains, WW domain, 03 medical and health sciences, Animals, Cell Proliferation, 030304 developmental biology, General Immunology and Microbiology, Cell growth, E. coli, Proteins, 030104 developmental biology, Structural biology, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc7bb47a7e9d98ef8d4e659d8a222d6Test
https://doi.org/10.1101/694976Test -
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المؤلفون: Kun-Liang Guan, Inder M. Verma, Jolene K. Diedrich, Yasushi Soda, Audrey W. Hong, Steve Plouffe, Narayana Yeddula, James J. Moresco, Sachin Verma, Gerald M. Pao, Quan Zhu, Toshiro Moroishi
المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 15
مصطلحات موضوعية: Hippo, Ubiquitin, 2.1 Biological and endogenous factors, Aetiology, skin and connective tissue diseases, YAP1, Neurofibromin 2, Tumor, Multidisciplinary, biology, Chemistry, BRCA1 Protein, Adaptor Proteins, Cell biology, Ubiquitin ligase, PNAS Plus, Phosphorylation, Female, Signal Transduction, 1.1 Normal biological development and functioning, Ubiquitin-Protein Ligases, Mutation, Missense, Breast Neoplasms, Protein Serine-Threonine Kinases, ubiquitination, Cell Line, Underpinning research, BARD1, Cell Line, Tumor, Breast Cancer, cancer, Humans, Hippo Signaling Pathway, Adaptor Proteins, Signal Transducing, Cell Proliferation, Hippo signaling pathway, Cell growth, Tumor Suppressor Proteins, Signal Transducing, Ubiquitination, YAP-Signaling Proteins, BRCA1, Phosphoproteins, HEK293 Cells, Amino Acid Substitution, NF2, Mutation, biology.protein, Ectopic expression, Generic health relevance, Missense, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7f8109eb2e6e151a1497c5527ee2fcTest
https://pubmed.ncbi.nlm.nih.gov/30918126Test -
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المؤلفون: Hai Xin Yuan, Audrey W. Hong, Delong Meng, Fa-Xing Yu, Wai Ling Macrina Lam, Kun-Liang Guan, Susan S. Taylor, Jenna L. Jewell, Vivian Fu, Chase H. Melick, Huanyu Wang
المصدر: eLife
eLife, Vol 8 (2019)مصطلحات موضوعية: 0301 basic medicine, mTORC1, Receptors, G-Protein-Coupled, 0302 clinical medicine, Receptors, cell biology, 2.1 Biological and endogenous factors, Aetiology, Biology (General), Phosphorylation, Receptor, cancer biology, Cancer Biology, Chemistry, General Neuroscience, General Medicine, Cell biology, Medicine, Signal transduction, biological phenomena, cell phenomena, and immunity, Signal Transduction, Research Article, Human, Gs alpha subunit, QH301-705.5, 1.1 Normal biological development and functioning, Science, Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, G-Protein-Coupled, Underpinning research, Animals, Humans, human, Protein kinase A, Protein Processing, mouse, G protein-coupled receptor, General Immunology and Microbiology, Cell growth, Post-Translational, Regulatory-Associated Protein of mTOR, Cell Biology, Cyclic AMP-Dependent Protein Kinases, 030104 developmental biology, cancer cells, cells, Biochemistry and Cell Biology, Protein Processing, Post-Translational, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffb298648d804f7699381ac8a2b44fdTest
https://pubmed.ncbi.nlm.nih.gov/31112131Test -
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المؤلفون: Yi Ping Sun, Yue Xiong, Peng Liu, Zhen Wang, Hai Xin Yuan, Xin Zhou, Tian-Xiang Wang, Xu Feng, Kun-Liang Guan
المصدر: Cancer research, vol 77, iss 9
مصطلحات موضوعية: 0301 basic medicine, rho GTP-Binding Proteins, Cancer Research, Carcinogenesis, GTPase, medicine.disease_cause, law.invention, law, Cell Movement, 2.1 Biological and endogenous factors, Aetiology, Endothelin A, Cancer, Endothelin-1, Chemistry, Intracellular Signaling Peptides and Proteins, Adaptor Proteins, Signal transducing adaptor protein, Receptor, Endothelin A, GTP-Binding Protein alpha Subunits, Colo-Rectal Cancer, Gene Expression Regulation, Neoplastic, Oncology, Colonic Neoplasms, Receptor, medicine.medical_specialty, Oncology and Carcinogenesis, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, Oncology & Carcinogenesis, Transcription factor, Adaptor Proteins, Signal Transducing, Cell Proliferation, Neoplastic, Hippo signaling pathway, Cell growth, Signal Transducing, YAP-Signaling Proteins, HCT116 Cells, Phosphoproteins, Endothelin 1, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Cancer research, Trans-Activators, Suppressor, Digestive Diseases, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aafcd8fb7d5a2241eaf5290a42a28a4Test
https://europepmc.org/articles/PMC6724531Test/ -
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المؤلفون: Chen Ying Liu, Yi Ping Sun, Xian Bo Lv, Yue Xiong, Zhen Wang, Kun-Liang Guan, Qun-Ying Lei
المصدر: EMBO reports, vol 16, iss 8
مصطلحات موضوعية: TAZ, Hippo pathway, tight junction, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Biochemistry, Cell Line, Dephosphorylation, Cell Line, Tumor, Cell polarity, Genetics, Phosphoprotein Phosphatases, Humans, Hippo Signaling Pathway, Phosphorylation, Molecular Biology, Adaptor Proteins, Signal Transducing, Cell Proliferation, Hippo signaling pathway, Tumor, Tight Junction Proteins, Cell growth, Kinase, Chemistry, HEK 293 cells, Scientific Reports, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Cell Polarity, Protein-Serine-Threonine Kinases, Cell biology, HEK293 Cells, Gene Expression Regulation, PARD3, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Cancer research, Trans-Activators, Biochemistry and Cell Biology, Signal transduction, Transcription Factors, Signal Transduction, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e09eb5c49458057a4c4e72cb3c36a7Test
https://escholarship.org/uc/item/5bz6f6vcTest -
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المؤلفون: Ken Inoki, Kun-Liang Guan, Raymond S. Yeung, Yong Li
المصدر: Journal of Biological Chemistry. 277:44593-44596
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Tyrosine 3-Monooxygenase, Tumor suppressor gene, Recombinant Fusion Proteins, Cell Cycle Proteins, Protein Serine-Threonine Kinases, medicine.disease_cause, Ribosomal Protein S6 Kinases, 90-kDa, Biochemistry, Tuberous Sclerosis Complex 1 Protein, Cell Line, Ribosomal s6 kinase, Tuberous Sclerosis, Proto-Oncogene Proteins, Tuberous Sclerosis Complex 2 Protein, Serine, medicine, Animals, Humans, Genes, Tumor Suppressor, Phosphorylation, Molecular Biology, Adaptor Proteins, Signal Transducing, Mutation, Binding Sites, biology, Chemistry, Cell growth, Tumor Suppressor Proteins, Proteins, Cell Biology, Phosphoproteins, nervous system diseases, Repressor Proteins, medicine.anatomical_structure, 14-3-3 Proteins, Cancer research, biology.protein, TSC1, TSC2, Carrier Proteins, Proto-Oncogene Proteins c-akt, Function (biology), Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923ec245edd0d24b8219364a38d1b672Test
https://doi.org/10.1074/jbc.c200510200Test
