التفاصيل البيبلوغرافية
| العنوان: |
Apoptosis, the dermatologist, the venereologist and the patient. |
| المؤلفون: |
Gaffney, Eoin F.1, Cotter, Thomas G.2 |
| المصدر: |
Journal of the European Academy of Dermatology & Venereology. Aug95, Vol. 5 Issue 1, p1-8. 8p. |
| مصطلحات موضوعية: |
*APOPTOSIS, *DERMATOLOGY, *HIV, *ONCOGENES, *CANCER, *CELL death |
| مستخلص: |
Apoptosis is the genetically mediated process whereby individual cells determine their deletion from normal and diseased tissues. Deregulation of apoptosis occurs to a greater or Lesser extent in malignant tumors and in certain skin diseases, and also largely accounts for the progressive depletion of CD4[sup+] lymphocytes in HIV infection. Greater understanding of apoptosic modulation by oncogenes and tumor suppressor genes such as c-myc, Fas, p53, bcl-2, and abl will facilitate the development of new therapeutic strategies for cancer and other diseases. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
