التفاصيل البيبلوغرافية
| العنوان: |
and spermatogenesis REVIEW |
| المؤلفون: |
Yan-ho Cheng, Elissa W. P. Wong, C. Yan Cheng |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
http://www.landesbioscience.com/journals/spermatogenesis/Cheng2SPMG1-3.pdfTest. |
| المجموعة: |
CiteSeerX |
| مصطلحات موضوعية: |
These authors contributed equally to this work. Key words, testis, spermatogenesis, cancer/testis antigens, seminiferous epithelial cycle, cell cycle progression, mitosis, meiosis, spermatogonia, spermatogonial stem cells, spermatocytes, spermatids, spermatozoa, tumorigenesis, cancer During spermatogenesis, undifferentiated |
| الوصف: |
and differentiated spermatogonia, spermatocytes, spermatids and spermatozoa all express specific antigens, yet the functions of many of these antigens remain unexplored. Studies in the past three decades have shown that many of these transiently expressed genes in developing germ cells are proto-oncogenes and oncogenes, which are expressed only in the testis and various types of cancers in humans and rodents. As such, these antigens are designated cancer/testis antigens (CT antigens). Since the early 1980s, about 70 families of CT antigens have been identified with over 140 members are known to date. Due to their restricted expression in the ©2011LandesBioscience. Donotdistribute. testis and in various tumors in humans, they have been used as the target of immunotherapy. Multiple clinical trials at different |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.338.85Test; http://www.landesbioscience.com/journals/spermatogenesis/Cheng2SPMG1-3.pdfTest |
| الإتاحة: |
http://www.landesbioscience.com/journals/spermatogenesis/Cheng2SPMG1-3.pdfTest |
| حقوق: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.2EF9F1AB |
| قاعدة البيانات: |
BASE |
