المؤلفون: Wiese, Wojciech¹ (AUTHOR) wojciech.wiese@stud.umed.lodz.pl, Barczuk, Julia¹ (AUTHOR) julia.barczuk@stud.umed.lodz.pl, Racinska, Olga¹ (AUTHOR) olga.racinska@stud.umed.lodz.pl, Siwecka, Natalia¹ (AUTHOR) natalia.siwecka@stud.umed.lodz.pl, Rozpedek-Kaminska, Wioletta¹ (AUTHOR) wioletta.rozpedek@umed.lodz.pl, Slupianek, Artur² (AUTHOR) aslupian@temple.edu, Sierpinski, Radoslaw³ (AUTHOR) r.sierpinski@uksw.edu.pl, Majsterek, Ireneusz¹ (AUTHOR) ireneusz.majsterek@umed.lodz.pl

المصدر: Cancers. Nov2023, Vol. 15 Issue 21, p5297. 18p.

مصطلحات موضوعية: *PHOSPHOTRANSFERASES, *MTOR inhibitors, *LEUKEMIA, *CELLULAR signal transduction, *CELL cycle, *HEMATOLOGIC malignancies, *CELL proliferation

المؤلفون: Zhao, Weidong, Zhao, Xiaohan, Xu, Menglin, Cheng, Zhengwu, Zhang, Zhengxiang

المصدر: Journal of Oncology; 11/8/2022, p1-12, 12p

مصطلحات موضوعية: STOMACH tumors, BIOLOGICAL models, IN vitro studies, NONPARAMETRIC statistics, IN vivo studies, XENOGRAFTS, ANALYSIS of variance, ANIMAL experimentation, WESTERN immunoblotting, MTOR inhibitors, METASTASIS, LYMPH nodes, CELL motility, CELLULAR signal transduction, T-test (Statistics), GENE expression, CELL cycle, CELL proliferation, DESCRIPTIVE statistics, CHI-squared test, KAPLAN-Meier estimator, SURVIVAL analysis (Biometry), TUMOR markers, CELL lines, POLYMERASE chain reaction, DATA analysis software, MICE, PHOSPHORYLATION

المؤلفون: Xie, Hui, Rutz, Jochen, Maxeiner, Sebastian, Grein, Timothy, Thomas, Anita, Juengel, Eva, Chun, Felix K.-H., Cinatl, Jindrich, Haferkamp, Axel, Tsaur, Igor, Blaheta, Roman A.

المصدر: Cancers; Oct2022, Vol. 14 Issue 19, p4682, 18p

مصطلحات موضوعية: BLADDER tumors, SULFUR compounds, IN vitro studies, DISEASE progression, MTOR inhibitors, CELL cycle, CELL proliferation, DESCRIPTIVE statistics, PLANT extracts, DRUG allergy, CELL lines, DRUG resistance in cancer cells

المؤلفون: Lu, Zhaoming, Shi, Xiaojing, Gong, Fanghua, Li, Shenglei, Wang, Yang, Ren, Yandan, Zhang, Mengyin, Yu, Bin, Li, Yan, Zhao, Wen, Zhang, Jianying, Hou, Guiqin

المصدر: Acta Pharmaceutica Sinica B; Jun2020, Vol. 10 Issue 6, p1004-1019, 16p

مصطلحات موضوعية: SQUAMOUS cell carcinoma, TREATMENT effectiveness, MTOR inhibitors, CELL cycle, CELL proliferation

المؤلفون: Seyed Mohammad Abedi, Samaneh Vaseghi, Nasrin Abbasi Gharibkandi, Alireza Mardanshahi, Sajjad Molavipordanjani

المصدر: Molecular Biology Reports. 48:1-14

مصطلحات موضوعية: Cell Survival, medicine.medical_treatment, Apoptosis, Radiation Tolerance, Phosphatidylinositol 3-Kinases, Cell Line, Tumor, Neoplasms, Autophagy, Genetics, medicine, Humans, Radiosensitivity, Protein Kinase Inhibitors, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Cell growth, Akt/PKB signaling pathway, business.industry, TOR Serine-Threonine Kinases, Cell Cycle, Cancer, MTOR Inhibitors, General Medicine, medicine.disease, Radiation therapy, Cancer research, business, Proto-Oncogene Proteins c-akt, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fdb87979d16875fbb742eee534b74bTest
https://doi.org/10.1007/s11033-021-06607-3Test

المؤلفون: Skarphedinn Halldorsson, Maria Tunset Grinde, Ottar Rolfsson, Qiong Wang, Sigurdur Trausti Karvelsson, Kotryna Seip, Gunhild Marie Maelandsmo, Freyr Jóhannsson, Siver Andreas Moestue, Arnar Sigurdsson

المصدر: Molecular Cancer Research

مصطلحات موضوعية: Cancer Research, Epithelial-Mesenchymal Transition, Glutamine, Apoptosis, Breast Neoplasms, Pentose Phosphate Pathway, chemistry.chemical_compound, Lipid biosynthesis, medicine, Tumor Cells, Cultured, Humans, Glycolysis, Molecular Biology, PI3K/AKT/mTOR pathway, Cell Proliferation, Chemistry, Cell Cycle, Cancer, Lipid metabolism, Mesenchymal Stem Cells, Glutathione, MTOR Inhibitors, medicine.disease, Oncology, Cell culture, Drug Resistance, Neoplasm, Cancer research, Metabolome, Female

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30918c45617bf8e18e4b058da4d64403Test
https://pubmed.ncbi.nlm.nih.gov/34088869Test

المؤلفون: Roberto Ballarino, Toyoaki Natsume, Laura Baranello, Rashid Mehmood, Radosław Grochowski, Anika Wiegard, Jan Grosser, Michele Ceribelli, Donald P. Cameron, Anna H. Bizard, Fedor Kouzine, Nicola Crosetto, Vladislav Kuzin, Arne Lindqvist, Ivana Karabogdan, Francesco Valant

المصدر: Wiegard, A, Kuzin, V, Cameron, D P, Grosser, J, Ceribelli, M, Mehmood, R, Ballarino, R, Valant, F, Grochowski, R, Karabogdan, I, Crosetto, N, Lindqvist, A, Bizard, A H, Kouzine, F, Natsume, T & Baranello, L 2021, ' Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1 ', Molecular Cell, vol. 81, no. 24, pp. 5007-5024.e9 . https://doi.org/10.1016/j.molcel.2021.10.015Test

مصطلحات موضوعية: Transcription, Genetic, Mitosis, RNA polymerase II, Biology, Chromosome segregation, Transcription (biology), Humans, supercoiling, Prometaphase, TOP1, Molecular Biology, Cell Proliferation, mitosis, topoisomerase, G1 Phase, Promoter, MTOR Inhibitors, Cell Biology, Chromatin Assembly and Disassembly, HCT116 Cells, segregation, Chromatin, Cell biology, Gene Expression Regulation, Neoplastic, ChIP-seq, polymerase, DNA Topoisomerases, Type I, biology.protein, Chromatin Immunoprecipitation Sequencing, DNA supercoil, cell cycle, RNA Polymerase II, RNAPII, Colorectal Neoplasms, transcription

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2285bb0b44adcf14340fca481f1e79Test
https://doi.org/10.1016/j.molcel.2021.10.015Test

المؤلفون: Mikhail V. Blagosklonny, Zoya N. Demidenko, Olga V. Leontieva

المصدر: Oncotarget

مصطلحات موضوعية: Senescence, Cyclin-Dependent Kinase Inhibitor p21, Aging, Indoles, senescence, Immunoblotting, mTORC1, Mechanistic Target of Rapamycin Complex 2, Biology, Mechanistic Target of Rapamycin Complex 1, Muscle hypertrophy, Cell Line, Tumor, Animals, Humans, quiescence, PI3K/AKT/mTOR pathway, Cellular Senescence, Cell Proliferation, Sirolimus, Dose-Response Relationship, Drug, Kinase, Cell growth, TOR Serine-Threonine Kinases, Blood Proteins, Cell cycle, Discovery and development of mTOR inhibitors, Cell biology, Oncology, Purines, geroconversion, Multiprotein Complexes, Research Perspective, mTOR

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddd208181c75c7d8ca6a1b625f7e2b4Test
https://pubmed.ncbi.nlm.nih.gov/26375366Test

المؤلفون: Matthew Trendowski, Tenzin Kusang, Thomas P. Fondy, Timothy D. Christen, Antoaneta A. Andonova, Berlini Narampanawe, Ashlee Thibaud

المصدر: Investigational New Drugs

مصطلحات موضوعية: Pharmacology, Cell Line, Tumor, medicine, Humans, Pharmacology (medical), MTOR inhibitors, Mechanistic target of rapamycin, Cytoskeleton, PI3K/AKT/mTOR pathway, Cell Proliferation, Cell Size, Sirolimus, Cytoskeletal-directed agents, Preclinical Studies, Antibiotics, Antineoplastic, Leukemia, Everolimus, Dose-Response Relationship, Drug, biology, Cell growth, TOR Serine-Threonine Kinases, U937 Cells, Cell cycle, Hematopoietic Stem Cells, Drug synergy, Oncology, Hematologic Neoplasms, biology.protein, Stem cell, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec86a3525b049791b8032aecbc23187Test