نتائج البحث - "Kaye J. Williams"

1

Tubulin-binding dibenz[c,e]oxepines: Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents

المؤلفون: Timothy W. Wallace, John A. Hadfield, Steven B. Rossington, Kaye J. Williams, Steven D. Shnyder

المصدر: Rossington, S, Hadfield, J, Shnyder, S D, Wallace, T & Williams, K 2017, ' Tubulin-binding dibenz[c,e]oxepines : Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents ', Bioorganic and Medicinal Chemistry, vol. 25, no. 5, pp. 1630-1642 . https://doi.org/10.1016Test/j.bmc.2017.01.027

مصطلحات موضوعية: Necrosis, Clinical Biochemistry, Pharmaceutical Science, Tumour vasculature, 01 natural sciences, Biochemistry, Tubulin binding, Structural variation, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tubulin, Cell Line, Tumor, Neoplasms, Biological property, Drug Discovery, Journal Article, medicine, Animals, Humans, Colchicine, Molecular Biology, Biological evaluation, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, direct arylation, Organic Chemistry, palladium catalyst, 0104 chemical sciences, tubulin, chemistry, Cell culture, 030220 oncology & carcinogenesis, biology.protein, Heterografts, Molecular Medicine, medicine.symptom, Dibenzoxepins

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7159b0428917a521e7ecb361504f199Test
https://doi.org/10.1016Test/j.bmc.2017.01.027

2

High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma

المؤلفون: Joanna Dutko-Gwozdz, Omar N. Pathmanaban, Peter Cueppens, Kenny Yu, Brian A. Telfer, Gareth Griffiths, Ian Peers, Roderick Benson, Kaye J. Williams, Brian W. Bigger, Deniz Beyit, Catherine McBain, Ian Kamaly-Asl, Amir Saam Youshani, Jessica T. Taylor

المصدر: PLoS ONE
Yu, K K H, Taylor, J T, Pathmanaban, O N, Youshani, A S, Beyit, D, Dutko-Gwozdz, J, Benson, R, Griffiths, G, Peers, I, Cueppens, P, Telfer, B A, Williams, K J, McBain, C, Kamaly-Asl, I D & Bigger, B W 2018, ' High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma ', PLoS ONE, vol. 13, no. 3, e0193694 . https://doi.org/10.1371/journal.pone.0193694Test
PLoS ONE, Vol 13, Iss 3, p e0193694 (2018)

مصطلحات موضوعية: 0301 basic medicine, Cancer Treatment, lcsh:Medicine, Apoptosis, Mice, SCID, Bortezomib, Mice, 0302 clinical medicine, Mice, Inbred NOD, Medicine and Health Sciences, Tumor Cells, Cultured, Medicine, Blastomas, lcsh:Science, Neurological Tumors, Staining, Multidisciplinary, Cell Death, Brain Neoplasms, Cell Staining, Oncology, Neurology, Cell Processes, 030220 oncology & carcinogenesis, High-content screening, Neoplastic Stem Cells, Female, Biological Cultures, medicine.drug, Research Article, Transplantation, Heterologous, Surgical and Invasive Medical Procedures, Antineoplastic Agents, Research and Analysis Methods, 03 medical and health sciences, In vivo, Cancer stem cell, Neurosphere, Animals, Humans, Cell Proliferation, Pharmacology, Mitoxantrone, Drug Screening, Surgical Resection, business.industry, lcsh:R, Biology and Life Sciences, Cancers and Neoplasms, Cell Biology, Cell Cultures, Transplantation, Nuclear Staining, 030104 developmental biology, Cell culture, Specimen Preparation and Treatment, Drug Resistance, Neoplasm, Gamma Rays, Cancer research, lcsh:Q, Neurospheres, business, Glioblastoma, Glioblastoma Multiforme

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62738a9c8f7a45480d33d24e41cc123dTest
http://europepmc.org/articles/PMC5834163Test

3

The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy

المؤلفون: Philippe Lambin, Ludwig Dubois, Ala Yaromina, Natasja G. Lieuwes, R. Biemans, Brian A. Telfer, Guido R.M.M. Haenen, Kaye J. Williams, Raymon Niemans, Simon J. A. van Kuijk, Roben G. Gieling

المساهمون: RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Promovendi ODB, Radiotherapie, Ondersteunend personeel ODB, Farmacologie en Toxicologie, RS: CARIM - R3.05 - Vascular remodeling in cardiovascular disease, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting

المصدر: PLOS ONE, 11(8):e0161040. Public Library of Science
PLoS ONE, Vol 11, Iss 8, p e0161040 (2016)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Physiology, Cancer Treatment, lcsh:Medicine, Pharmacology, Toxicology, Pathology and Laboratory Medicine, Biochemistry, Mice, 0302 clinical medicine, Tumor Cells, Cultured, Medicine and Health Sciences, Carbonic Anhydrase Inhibitors, Hypoxia, lcsh:Science, Cell Analysis, Carbonic Anhydrases, Sulfonamides, Multidisciplinary, Antibiotics, Antineoplastic, Chemistry, Cell Hypoxia, 3. Good health, Enzymes, Gene Expression Regulation, Neoplastic, Bioassays and Physiological Analysis, Oncology, Physiological Parameters, 030220 oncology & carcinogenesis, Physical Sciences, Cell lines, Female, Biological cultures, medicine.drug, Research Article, Cell Viability Testing, Combination therapy, Mice, Nude, Breast Neoplasms, 03 medical and health sciences, In vivo, medicine, Animals, Humans, Doxorubicin, Viability assay, Carbonic Anhydrase IX, IC50, HT29 cells, Cell Proliferation, Toxicity, Cell growth, Phenylurea Compounds, Body Weight, lcsh:R, Chemical Compounds, Biology and Life Sciences, Proteins, Cell Biology, Carbon Dioxide, A300, Xenograft Model Antitumor Assays, In vitro, Research and analysis methods, 030104 developmental biology, Cell culture, Enzymology, lcsh:Q

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0015a9f0028d8ab1a88076adbb66f6a8Test

4

Irradiation Decreases the Neuroendocrine Biomarker Pro-Opiomelanocortin in Small Cell Lung Cancer Cells In Vitro and In Vivo

المؤلفون: Roya Behrouzi, Anne White, Muhammad Babur, Jennifer L. Bryant, Philip Riddell, Suzanne Meredith, Kaye J. Williams

المصدر: PLOS ONE
Meredith, S, Bryant, J, Babur, M, Riddell, P W, Behrouzi, R, Williams, K & White, A 2016, ' Irradiation Decreases the Neuroendocrine Biomarker Pro-Opiomelanocortin in Small Cell Lung Cancer Cells In Vitro and In Vivo. ', P L o S One, vol. 11, no. 2, e0148404 . https://doi.org/10.1371/journal.pone.0148404Test
PLoS ONE, Vol 11, Iss 2, p e0148404 (2016)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Pathology, Lung Neoplasms, Pro-Opiomelanocortin, medicine.medical_treatment, Cancer Treatment, Gene Expression, lcsh:Medicine, Biochemistry, Lung and Intrathoracic Tumors, Mesoderm, Small Cell Lung Cancer, Mice, 0302 clinical medicine, Medicine and Health Sciences, Enzyme-Linked Immunoassays, lcsh:Science, Staining, Multidisciplinary, Cell Staining, Animal Models, Phenotype, 3. Good health, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Small Cell Lung Carcinoma, hormones, hormone substitutes, and hormone antagonists, Research Article, endocrine system, medicine.medical_specialty, Radiation Therapy, Mouse Models, Biology, Research and Analysis Methods, 03 medical and health sciences, Model Organisms, Neuroendocrine Cells, In vivo, Cell Line, Tumor, medicine, Genetics, Biomarkers, Tumor, Animals, Humans, Immunoassays, neoplasms, Cell Proliferation, Cell growth, lcsh:R, Cancers and Neoplasms, Biology and Life Sciences, Dose-Response Relationship, Radiation, In vitro, respiratory tract diseases, Radiation therapy, 030104 developmental biology, Cell culture, Specimen Preparation and Treatment, Immunologic Techniques, lcsh:Q, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d8c47a6ce1d3b3942e445026a80909Test

5

Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells

المؤلفون: Warwick B. Dunn, Kaye J. Williams, Royston Goodacre, Helen L. Kotze, J. William Allwood, Emily G. Armitage

المصدر: Armitage, E G, Kotze, H L, Allwood, J W, Dunn, W B, Goodacre, R & Williams, K 2015, ' Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells ', Scientific Reports, vol. 5, 15649, pp. 1-12 . https://doi.org/10.1038/srep15649Test
Armitage, E G, Kotze, H L, Allwood, J W, Dunn, W B, Goodacre, R & Williams, K 2015, ' Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells ' Scientific Reports, vol. 5, 15649, pp. 1-12 . https://doi.org/10.1038/srep15649Test
Scientific Reports