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المؤلفون: Hannah Prendeville, Cathal Harmon, Nika N. Danial, Anita Reddy, Edward T. Chouchani, Accalia Fu, Nhien V. Tran, Ryan Garrity, Lydia Lynch, Steven P. Gygi, Evanna L. Mills, John Szpyt, Haopeng Xiao, Mark P. Jedrychowski, Gary A. Bradshaw
المصدر: Nat Metab
مصطلحات موضوعية: medicine.medical_specialty, Adipose Tissue, White, Endocrinology, Diabetes and Metabolism, Succinic Acid, Adipose tissue, Inflammation, Biology, Article, Hepatitis, Receptors, G-Protein-Coupled, Pathogenesis, Mice, Non-alcoholic Fatty Liver Disease, Stress, Physiological, Physiology (medical), Internal medicine, Glucose Intolerance, Internal Medicine, Succinate receptor 1, medicine, Humans, Animals, Uncoupling Protein 1, Fatty liver, Cell Biology, Adipose Tissue, Beige, medicine.disease, Fibrosis, Thermogenin, Glucose, Endocrinology, Hepatic stellate cell, Disease Susceptibility, medicine.symptom, Extracellular Space, Thermogenesis, Metabolic Networks and Pathways, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19452567cd920c53d527e8394df462aTest
https://doi.org/10.1038/s42255-021-00389-5Test -
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المؤلفون: John Szpyt, Bruce M. Spiegelman, Steven P. Gygi, Haopeng Xiao, Michael P. Murphy, Nhien Tran, Ryan Garrity, Evanna L. Mills, Anja V. Gruszczyk, Cathal Harmon, Gary A. Bradshaw, Edward T. Chouchani, Lydia Lynch, Hannah Prendeville, Mark P. Jedrychowski, Dina Laznik-Bogoslavski
المصدر: Cell Metab
مصطلحات موضوعية: Male, medicine.medical_specialty, Physiology, medicine.drug_class, Regulator, Adipose tissue, Inflammation, Regulatory site, Biology, Article, Mice, Adipose Tissue, Brown, Internal medicine, Genetic model, medicine, Animals, Cysteine, Molecular Biology, Uncoupling Protein 1, Thermogenesis, Cell Biology, Thermogenin, Endocrinology, Adipose Tissue, Estrogen, Female, medicine.symptom, Energy Metabolism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdb71b25e4f336f6c2fb959e4865721Test
https://doi.org/10.1016/j.cmet.2021.11.003Test -
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المؤلفون: Han Dong, Ayano C. Kohlgruber, Lydia Lynch, Harry Kane, Michael B. Brenner, Nelson M. LaMarche
المصدر: Cell Metab
Cell Metabolismمصطلحات موضوعية: 0301 basic medicine, Adoptive cell transfer, Physiology, Cell, Adipose tissue, Inflammation, Biology, Article, 03 medical and health sciences, Interferon-gamma, Mice, 0302 clinical medicine, medicine, Macrophage, Animals, Homeostasis, Molecular Biology, Mice, Knockout, Cell Biology, Endoplasmic Reticulum Stress, Cell biology, Interleukin-10, Mice, Inbred C57BL, Interleukin 10, 030104 developmental biology, medicine.anatomical_structure, Adipose Tissue, Unfolded protein response, Natural Killer T-Cells, medicine.symptom, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a20b7dda5a19e282fd2179fc0d5399Test
https://europepmc.org/articles/PMC8234787Test/ -
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المؤلفون: Ayano C. Kohlgruber, Claire McIntyre, Bruno Silva-Santos, Mathilde Raverdeau, Lydia Dyck, Noëlla Lopes, Róisín M. Loftus, Leandro Z. Agudelo, Rafael J. Argüello, Nital Sumaria, Aaron Douglas, Philippe Pierre, Manolis Kellis, Hannah Prendeville, Harry Kane, Stefania Martin, Stephen Cunningham, Daniel J. Pennington, Michael B. Brenner, Gina J. Fiala, Colleen Carmody, Lydia Lynch
المساهمون: Trinity College Dublin, Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Computer Science and Artificial Intelligence Laboratory [Cambridge] (CSAIL), Massachusetts Institute of Technology (MIT), Harvard Medical School [Boston] (HMS), Queen Mary University of London (QMUL), Repositório da Universidade de Lisboa, Universidade de Lisboa - Instituto de Medicina Molecular João Lobo Antunes, Brigham & Women’s Hospital [Boston] (BWH), Blizard Institute, Universidade de Lisboa - Instituto de Medicina Molecular João Lobo Antune, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)
المصدر: Nature immunology
Nature Immunology
Nature Immunology, Nature Publishing Group, 2021, 22 (2), pp.179-192. ⟨10.1038/s41590-020-00848-3⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Immunology, 2021, 22 (2), pp.179-192. ⟨10.1038/s41590-020-00848-3⟩مصطلحات موضوعية: 0301 basic medicine, Adoptive cell transfer, medicine.medical_treatment, Melanoma, Experimental, Immunotherapy, Adoptive, 0302 clinical medicine, Cancer immunotherapy, Interferon, T-Lymphocyte Subsets, Tumor Microenvironment, Immunology and Allergy, Interleukin-17, Receptors, Antigen, T-Cell, gamma-delta, 3. Good health, Cell biology, Mitochondria, Tumor Burden, medicine.anatomical_structure, Phenotype, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, Colonic Neoplasms, Female, Glycolysis, medicine.drug, Signal Transduction, T cell, Immunology, [SDV.CAN]Life Sciences [q-bio]/Cancer, Breast Neoplasms, Mice, Transgenic, Thymus Gland, Biology, Article, 03 medical and health sciences, Interferon-gamma, Immune system, Lymphocytes, Tumor-Infiltrating, Organ Culture Techniques, Antigen, Cell Line, Tumor, medicine, Animals, Humans, Cell Lineage, Obesity, Tumor microenvironment, Immunotherapy, Lipid Metabolism, Mice, Inbred C57BL, 030104 developmental biology, Glucose, Energy Metabolism, 030215 immunology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260b51c089faeb170e0f58ebc08a358fTest
https://pubmed.ncbi.nlm.nih.gov/33462452Test -
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المؤلفون: Steven P. Gygi, Wei Song, Shangyu Hong, Colin J. Palmer, Peter-James H. Zushin, Dimitrije Cabarkapa, Alexander S. Banks, Jessica A. Hall, John Szpyt, Norbert Perrimon, Bingyang Liu, Mark P. Jedrychowski, Zhaoming Deng, Hassan Aliakbarian, Amir I. Mina, Ali Tavakkoli, Lydia Lynch
المصدر: Molecular Metabolism, Vol 12, Iss, Pp 25-38 (2018)
Molecular Metabolismمصطلحات موضوعية: 0301 basic medicine, Beta-3 adrenergic receptor, MAPK/ERK pathway, lcsh:Internal medicine, medicine.medical_specialty, MAP Kinase Signaling System, Lipolysis, Adipocytes, White, Adipose, Adipose tissue, White adipose tissue, Mice, 03 medical and health sciences, chemistry.chemical_compound, Beta adrenergic receptor, Adipocyte, Internal medicine, Serine, medicine, Animals, Humans, Obesity, Phosphorylation, lcsh:RC31-1245, Molecular Biology, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Free fatty acid, Insulin resistance, 3T3 Cells, Cell Biology, Mice, Inbred C57BL, ERK, Drosophila melanogaster, 030104 developmental biology, Endocrinology, chemistry, Fat, Receptors, Adrenergic, beta-3, Original Article, Thermogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c9cfd495ddb3971811142ae6016865Test
https://doi.org/10.1016/j.molmet.2018.03.012Test -
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المؤلفون: Nelson M. LaMarche, Ayano C. Kohlgruber, Tyler Paras, Danielle Duquette, Lydia Lynch, Alexander S. Banks, Amir I. Mina, Adam P Uldrich, Shani T. Gal-Oz, Dale I. Godfrey, Michael B. Brenner, Ali Tavakkoli, Ulrich H. von Andrian, Tal Shay, Hung N. Nguyen, Moto Shimazaki, Hui-Fern Koay
المصدر: Nature Immunology
Nat Immunolمصطلحات موضوعية: Male, 0301 basic medicine, Regulatory T cell, T cell, Immunology, Adipose tissue, Biology, T-Lymphocytes, Regulatory, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Antigen, T-Lymphocyte Subsets, medicine, Animals, Homeostasis, Humans, Immunology and Allergy, Obesity, Mice, Knockout, Interleukin-17, Interleukin, Receptors, Antigen, T-Cell, gamma-delta, Thermogenesis, Cell biology, Mice, Inbred C57BL, Interleukin 33, 030104 developmental biology, medicine.anatomical_structure, Adipose Tissue, Tumor necrosis factor alpha, Interleukin 17, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3d13712180acc84fb197c66a84ce82Test
https://doi.org/10.1038/s41590-018-0094-2Test -
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المؤلفون: Vanessa Zaiatz-Bittencourt, Nadine Assmann, Lydia Lynch, Clair M. Gardiner, Róisín M. Loftus, Raymond P. Donnelly, Katie L. O’Brien, David K. Finlay, Katja Dettmer, Paul Heinrich, Peter J. Oefner, Lydia Dyck
المصدر: Nature Immunology. 18:1197-1206
مصطلحات موضوعية: 0301 basic medicine, Immunoblotting, Immunology, Oxidative phosphorylation, Oxidative Phosphorylation, 03 medical and health sciences, T-Lymphocyte Subsets, Animals, Humans, Immunology and Allergy, Glycolysis, Transcription factor, Cell Proliferation, Chemistry, Effector, Cell growth, Lipid metabolism, Flow Cytometry, Lipids, Sterol regulatory element-binding protein, Cell biology, Killer Cells, Natural, Metabolic pathway, Glucose, 030104 developmental biology, Cytokines, lipids (amino acids, peptides, and proteins), Sterol Regulatory Element Binding Protein 1, Sterol Regulatory Element Binding Protein 2
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1801ed92f84290b2f7aae9c7d83f60Test
https://doi.org/10.1038/ni.3838Test -
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المؤلفون: Daniel J. Drucker, Alexander S. Banks, Bing Lu, Lydia Lynch, Danielle Duquette, Abhisek Ghosh, Donal O'Shea, Andrew E. Hogan, Michael B. Brenner, Eleftheria Maratos-Flier, Michelle Corrigan, David E. Cohen, Chantel Lester, Darko Stevanovic, Katherine B. LeClair
المصدر: Cell Metabolism
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, FGF21, Physiology, Adipose Tissue, White, Adipose tissue, 030209 endocrinology & metabolism, Biology, 03 medical and health sciences, 0302 clinical medicine, Adipose Tissue, Brown, Glucagon-Like Peptide 1, Weight loss, Internal medicine, Weight Loss, medicine, Animals, Humans, Receptor, Molecular Biology, 2. Zero hunger, Liraglutide, Thermogenesis, Cell Biology, Natural killer T cell, Fibroblast Growth Factors, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Immunology, Natural Killer T-Cells, medicine.symptom, Cell activation, medicine.drug
وصف الملف: text
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c14831c4385f53ae56c510c4b2ac9daTest
https://doi.org/10.1016/j.cmet.2016.08.003Test -
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المؤلفون: Ronan Bergin, Natacha Veerapen, Donal O'Shea, Cathriona Foley, Andrew E. Hogan, Gurdyal S. Besra, Frances C. Tinley, Róisín M. Loftus, Marta M. Pisarska, Arimin Mat, Laura Tobin, Ciaran Bannan, Paul N. Moynagh, Gary Sommerville, Linda V. Sinclair, Aisling M. O'Brien, David K. Finlay, Lydia Lynch, Nicole A. W. Wood
المصدر: Journal of immunology (Baltimore, Md. : 1950). 202(12)
مصطلحات موضوعية: Adult, Male, medicine.medical_treatment, Immunology, Population, Cell, Mucosal associated invariant T cell, mTORC1, Biology, Mechanistic Target of Rapamycin Complex 1, Lymphocyte Activation, Mucosal-Associated Invariant T Cells, Large Neutral Amino Acid-Transporter 1, 03 medical and health sciences, Interferon-gamma, 0302 clinical medicine, Immune system, Downregulation and upregulation, medicine, Immunology and Allergy, Humans, Obesity, education, Cells, Cultured, education.field_of_study, Effector, Sequence Analysis, RNA, Cell biology, medicine.anatomical_structure, Cytokine, Diabetes Mellitus, Type 2, Female, Glycolysis, 030215 immunology, Signal Transduction
وصف الملف: text
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494246a829a2194bf252feceb5dc222aTest
https://pubmed.ncbi.nlm.nih.gov/31076528Test -
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المؤلفون: Stephanie J. Crowley, Stephanie K. Dougan, Nelson M. LaMarche, Hee-Jin Jeong, Lestat R. Ali, Gui Zhen Chen, Kelly Boelaars, Eleanor Clancy-Thompson, Lydia Lynch, Michael B. Brenner
المصدر: The EMBO Journal
مصطلحات موضوعية: Chemokine, Nuclear Transfer Techniques, medicine.medical_treatment, Population, Immunology, Peyer's patches, Galactosylceramides, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, RAR-related orphan receptor gamma, medicine, Animals, Promyelocytic Leukemia Zinc Finger Protein, education, Molecular Biology, B cell, Tissue homeostasis, Cells, Cultured, 030304 developmental biology, 0303 health sciences, education.field_of_study, IL‐4, tissue‐resident iNKT cells, General Immunology and Microbiology, biology, General Neuroscience, Gene Expression Profiling, Vaccination, Peyer's patch, Cell Differentiation, Articles, Nuclear Receptor Subfamily 1, Group F, Member 3, Immunoglobulin Class Switching, transnuclear mice, 3. Good health, Cell biology, oral vaccines, medicine.anatomical_structure, Cytokine, Immunoglobulin class switching, Immunoglobulin G, biology.protein, Natural Killer T-Cells, Female, Interleukin-4, T-Box Domain Proteins, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c32a86ecc84e72783bec8a01a402353Test
https://pubmed.ncbi.nlm.nih.gov/31304630Test