المؤلفون: Julien Ferent, Sandii Constable, Laura E. Mariani, Emilie Legué, Patricia T. Yam, Eduardo D. Gigante, Karel F. Liem, Frédéric Charron, Tamara Caspary

المصدر: Cell Reports, Vol 29, Iss 11, Pp 3356-3366.e3 (2019)
Cell reports

مصطلحات موضوعية: 0301 basic medicine, animal structures, Growth Cones, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Animals, Small GTPase, Hedgehog Proteins, Cilia, Sonic hedgehog, Growth cone, lcsh:QH301-705.5, Cells, Cultured, ADP-Ribosylation Factors, Cilium, Commissure, Cell biology, Axon Guidance, 030104 developmental biology, lcsh:Biology (General), embryonic structures, biology.protein, Axon guidance, Neural development, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19c0bd0945be993fe681d45cd591980Test
http://www.sciencedirect.com/science/article/pii/S221112471931486XTest

المؤلفون: Lukas Tamayo-Orrego, Samer Salameh, Grant W. Brown, Andrew P. Jackson, David Gallo, Sushmetha Mohan, Frédéric Racicot, Trang Hoang, Brandon Ho, Amandine Bemmo, Frédéric Charron

المساهمون: Université de Montréal. Faculté de médecine. Département de médecine

المصدر: Nature Cancer
Tamayo Orrego, L, Gallo, D, Racicot, F, Bemmo, A, Mohan, S, Ho, B, Salameh, S, Hoang, T, Jackson, A P, Brown, G W & Charron, F 2020, ' Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma ', nature cancer . https://doi.org/10.1038/s43018-020-0094-7Test

مصطلحات موضوعية: DNA Replication, Cancer Research, animal structures, Carcinogenesis, Tumor initiation, Biology, medicine.disease_cause, Loss of heterozygosity, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Hedgehog Proteins, Homologous recombination, Sonic hedgehog, Cancer models, Cerebellar Neoplasms, Cancer, 030304 developmental biology, Medulloblastoma, 0303 health sciences, DNA replication, Origin firing, medicine.disease, Cell biology, CNS cancer, Oncology, PTCH1, embryonic structures, biology.protein, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4d4c4af099fd7b9ffa5fbc117c5f4aTest

المؤلفون: Patricia T. Yam, Frédéric Charron

المصدر: Nature Chemical Biology. 15:1030-1031

مصطلحات موضوعية: 0303 health sciences, Mechanism (biology), Chemistry, 030302 biochemistry & molecular biology, Cell Biology, Endocytosis, Axon growth, Cell biology, 03 medical and health sciences, nervous system, Extracellular, Phosphorylation, Axon guidance, Receptor, Molecular Biology, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7f77bf6b0060fa881616bc3af854bbbeTest
https://doi.org/10.1038/s41589-019-0383-6Test

المؤلفون: Frédéric Charron, Elisabeth Traiffort, Amina Zahaf, Mary Zakaria, Olivier Pascual, Abdelmoumen Kassoussi, Ines Hristovska, Yousra Laouarem, Marie-Eve Mayeur, Julien Ferent

المصدر: Development. 146

مصطلحات موضوعية: Male, Neurofilament, Blotting, Western, Intermediate Filaments, Receptors, Cell Surface, Cuprizone, Mice, 03 medical and health sciences, Myelin, 0302 clinical medicine, medicine, Animals, Hedgehog Proteins, Axon, Sonic hedgehog, Molecular Biology, Cells, Cultured, Myelin Sheath, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Microglia, biology, Macrophages, Cell Differentiation, Oligodendrocyte, Hedgehog signaling pathway, Myelin basic protein, Cell biology, Mice, Inbred C57BL, Oligodendroglia, medicine.anatomical_structure, nervous system, Immunoglobulin G, biology.protein, 030217 neurology & neurosurgery, Demyelinating Diseases, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4f6b00578939dbfbea779b59e7c2a5Test
https://doi.org/10.1242/dev.172502Test

المؤلفون: Frédéric Charron, Shannon M. Swikert, Lukas Tamayo-Orrego

المصدر: Cell Cycle

مصطلحات موضوعية: 0301 basic medicine, Senescence, Genome instability, preneoplasia, medicine.disease_cause, Loss of heterozygosity, sonic hedgehog, 03 medical and health sciences, Ptch1, medicine, Animals, Humans, Hedgehog Proteins, TP53, Sonic hedgehog, neoplasms, Molecular Biology, Cellular Senescence, Genetics, Medulloblastoma, Extra Views, biology, p53, Cell Biology, medicine.disease, Hedgehog signaling pathway, nervous system diseases, stomatognathic diseases, 030104 developmental biology, PTCH1, cell senescence, Mutation, Cancer research, biology.protein, Tumor Suppressor Protein p53, Carcinogenesis, Signal Transduction, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dc10099687a4223936d0c2abd20d41Test
https://doi.org/10.1080/15384101.2016.1189044Test

المؤلفون: Frédéric Charron, Sarah E. Millar, Andrew M. Overmiller, Julio C. Salas-Alanis, Molly R. Marous, Donna M. Brennan-Crispi, Felicia Cooper, Joya Sahu, Natalia A. Riobo-Del Galdo, Kathleen P. McGuinn, Ioanna Ch. Georgiou, Maxwell Frankfurter, Lukas Tamayo-Orrego, Mỹ G. Mahoney

المصدر: The Journal of investigative dermatology. 139(2)

مصطلحات موضوعية: 0301 basic medicine, STAT3 Transcription Factor, Skin Neoplasms, Mice, Transgenic, Dermatology, Biochemistry, Zinc Finger Protein GLI1, Article, 03 medical and health sciences, Paracrine signalling, Mice, 0302 clinical medicine, GLI1, Cell Line, Tumor, medicine, Animals, Humans, Basal cell carcinoma, Hedgehog Proteins, Gene Knock-In Techniques, Sonic hedgehog, Phosphorylation, Autocrine signalling, Molecular Biology, Hedgehog, Skin, Desmoglein 2, biology, integumentary system, Cadherin, Chemistry, Basal Cell Nevus Syndrome, Cell Biology, medicine.disease, Molecular biology, Hedgehog signaling pathway, Patched-1 Receptor, Disease Models, Animal, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7845adc461f95ef903a971c816e8faTest
https://pubmed.ncbi.nlm.nih.gov/30291846Test

المؤلفون: Steves Morin, Shirin Makihara, Frédéric Charron, Patricia T. Yam, Jean-François Côté, Julien Ferent

المصدر: Developmental cell. 46(4)

مصطلحات موضوعية: 0301 basic medicine, animal structures, Growth Cones, RAC1, Mice, Transgenic, Nerve Tissue Proteins, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, DOCK, medicine, Animals, Guanine Nucleotide Exchange Factors, Hedgehog Proteins, Axon, Sonic hedgehog, Cytoskeleton, Growth cone, Molecular Biology, Cells, Cultured, Adaptor Proteins, Signal Transducing, Neurons, biology, Dock3, GTPase-Activating Proteins, Gene Expression Regulation, Developmental, Cell Biology, Embryo, Mammalian, Axons, Cell biology, Axon Guidance, Cytoskeletal Proteins, 030104 developmental biology, medicine.anatomical_structure, Spinal Cord, embryonic structures, biology.protein, Axon guidance, Carrier Proteins, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8556b0a7f9cc136ddb8eb1499ae92131Test
https://pubmed.ncbi.nlm.nih.gov/30078728Test

المؤلفون: Christine Jolicoeur, Julien Ferent, Steves Morin, Michel Cayouette, Frédéric Charron, Jean-Francois Michaud, Fanny Giguère, Patricia T. Yam, Shirin Makihara

المصدر: Neuron. 102:1157-1171.e5

مصطلحات موضوعية: 0301 basic medicine, endocrine system, animal structures, Endosome, media_common.quotation_subject, Growth Cones, education, Endocytic cycle, Nerve Tissue Proteins, Receptors, Cell Surface, Endocytosis, Mice, 03 medical and health sciences, 0302 clinical medicine, Animals, Hedgehog Proteins, Sonic hedgehog, Internalization, health care economics and organizations, media_common, Floor plate, Neurons, biology, Chemistry, General Neuroscience, Membrane Proteins, Axon Guidance, Cell biology, Patched-1 Receptor, 030104 developmental biology, Gene Knockdown Techniques, Immunoglobulin G, embryonic structures, NUMB, biology.protein, Axon guidance, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d860514c964c09e6a3bd06ff4b5feeTest
https://doi.org/10.1016/j.neuron.2019.04.003Test

المؤلفون: Frédéric Charron

المصدر: Developmental Cell. 43:655-656

مصطلحات موضوعية: 0301 basic medicine, Cerebellum, Brain tumor, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Precursor cell, medicine, Humans, Hedgehog Proteins, Cerebellar Neoplasms, Molecular Biology, Hedgehog, Medulloblastoma, Translation (biology), Cell Biology, medicine.disease, Hedgehog signaling pathway, Cell biology, 030104 developmental biology, medicine.anatomical_structure, nervous system, biological phenomena, cell phenomena, and immunity, Signal Transduction, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed60b6295e9a3bc4318bf7043f4a0a60Test
https://doi.org/10.1016/j.devcel.2017.12.008Test

المؤلفون: Frédéric Charron

المصدر: PLoS Genetics
PLoS Genetics, Vol 11, Iss 9, p e1005441 (2015)

مصطلحات موضوعية: Cancer Research, Cell signaling, lcsh:QH426-470, Endosome, Endocytic cycle, Nerve Tissue Proteins, Biology, Endocytosis, Retinal ganglion, Genetics, Animals, Receptors, Immunologic, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, Body Patterning, Slit, Axons, Cell biology, Intracellular signal transduction, lcsh:Genetics, Perspective, Axon guidance, Drosophila, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3c746a87513b4711ccab040036560fTest
https://pubmed.ncbi.nlm.nih.gov/26334304Test