المؤلفون: Jonathan Schönfelder (11217173), Peter Benedikt Pfeiffer (11217176), Tejaswini Pradhan (11217179), Johan Bijzet (478976), Bouke P. C. Hazenberg (8041688), Stefan O. Schönland (8888558), Ute Hegenbart (5538473), Bernd Reif (1262229), Christian Haupt (11217182), Marcus Fändrich (54216)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Neuroscience, Ecology, Immunology, Developmental Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Amyloid structure, prion, protein misfolding, proteolytic stability, immunoglobulin light chain, transthyretin, serum amyloid A

العلاقة: https://figshare.com/articles/journal_contribution/Protease_resistance_of_i_ex_vivo_i_amyloid_fibrils_implies_the_proteolytic_selection_of_disease-associated_fibril_morphologies/15090326Test

الإتاحة: https://doi.org/10.6084/m9.figshare.15090326.v1Test

المؤلفون: Xinrui Gui, Shuang Feng, Zilong Li, Yanyan Li, Bernd Reif, Bingyang Shi, Zheng Niu

المصدر: Journal of Biological Chemistry. 299:102926

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1a68c867cbde27ad198c6850439a660aTest
https://doi.org/10.1016/j.jbc.2023.102926Test

المؤلفون: Sk Abdul Mohid, Karishma Biswas, TaeJun Won, Lakshmi S. Mallela, Arin Gucchait, Lena Butzke, Riddhiman Sarkar, Timothy Barkham, Bernd Reif, Enrico Leipold, Sanhita Roy, Anup K. Misra, Rajamani Lakshminarayanan, DongKuk Lee, Anirban Bhunia

المصدر: Biochimica et biophysica acta. Biomembranes. 1864(10)

مصطلحات موضوعية: Sterols, Antifungal Agents, Ergosterol, Cell Membrane, Biophysics, Cell Biology, Peptides, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b513032571177f12a65d77ca51e38cdTest
https://pubmed.ncbi.nlm.nih.gov/35753394Test

المؤلفون: Matthias J. Brandl, Tejaswini Pradhan, Johannes Buchner, Gina Feind, Carolin Berner, Benedikt Weber, Bernd Reif, Maria Daniela Pulido Cendales, Martin Zacharias

المصدر: Journal of Biological Chemistry. 293:17107-17118

مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Amino Acid Motifs, Lysine, Immunoglobulin domain, Protein aggregation, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Molecular dynamics, Protein Domains, Humans, Transition Temperature, Molecular Biology, Protein secondary structure, biology, Cell Biology, 030104 developmental biology, Monomer, chemistry, Immunoglobulin G, Protein Structure and Folding, Biophysics, biology.protein, Protein Conformation, beta-Strand, lipids (amino acids, peptides, and proteins), Protein folding, Immunoglobulin Domains, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4e744f62fedfcd0ca5690c5830597fTest
https://doi.org/10.1074/jbc.ra118.005475Test

المؤلفون: Stefanie Huhn, Marcus Fändrich, Bernd Reif, Ute Hegenbart, Riddhiman Sarkar, Tejaswini Pradhan, Stefan Schönland, Karthikeyan Annamalai

المصدر: The Journal of Biological Chemistry
J. Biol. Chem. 295, 18474-18484 (2020)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Amyloid, nuclear magnetic resonance (NMR), Sequence Homology, macromolecular substances, Protein aggregation, Fibril, Immunoglobulin light chain, Biochemistry, protein aggregation, 03 medical and health sciences, antibody, medicine, Humans, AL amyloidosis · antibody light chain · protein aggregation · fibril seeding · Magic Angle Spinning (MAS) solid-state NMR spectroscopy, Immunoglobulin Light-chain Amyloidosis, Amino Acid Sequence, Molecular Biology, Nuclear Magnetic Resonance, Biomolecular, solid state NMR, 030102 biochemistry & molecular biology, Chemistry, C-terminus, Amyloidosis, Point mutation, Cell Biology, Al Amyloidosis ·, Antibody Light Chain ·, Protein Aggregation ·, Fibril Seeding ·, Magic Angle Spinning (mas) Solid-state Nmr Spectroscopy, Antibody, Protein Aggregation, Solid State Nmr, Nuclear Magnetic Resonance (nmr), medicine.disease, 030104 developmental biology, Mutation, Protein Structure and Folding, Biophysics, Immunoglobulin Light Chains, Protein Conformation, beta-Strand, Salt bridge

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08beffb6b520e8806d11c3f5402b7a4cTest
https://pubmed.ncbi.nlm.nih.gov/33093170Test

المؤلفون: Gerd Multhaup, Bernd Reif, Lisa-Marie Munter, Daniela Kaden

المصدر: European Journal of Cell Biology. 91:234-239

مصطلحات موضوعية: Histology, biology, Chemistry, BACE1-AS, P3 peptide, Cell Biology, General Medicine, Pathology and Forensic Medicine, Biochemistry of Alzheimer's disease, Amyloid beta-Protein Precursor, Structure-Activity Relationship, Alpha secretase, Biochemistry, Alzheimer Disease, mental disorders, biology.protein, Amyloid precursor protein, Animals, Humans, APLP1, Protein Multimerization, Protein Dimerization, Amyloid precursor protein secretase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77126944554ed76246dd99895602118Test
https://doi.org/10.1016/j.ejcb.2011.01.017Test

المؤلفون: Gerd Multhaup, Elke Prade, Riddhiman Sarkar, Heiko J. Bittner, Juan Miguel López del Amo, Peter W. Hildebrand, Bernd Reif, Gerhard Althoff-Ospelt

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Amyloid, Plasma protein binding, macromolecular substances, Fibril, Biochemistry, Protein Structure, Secondary, Protein structure, Sulindac, Alzheimer Disease, mental disorders, medicine, Humans, Molecular Biology, Amyloid beta-Peptides, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Cell Biology, medicine.disease, Small molecule, Protein Structure and Folding, Biophysics, Salt bridge, Alzheimer's disease, Hydrophobic and Hydrophilic Interactions, medicine.drug, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f147c1d01b26fae101e527677407dc0Test
https://europepmc.org/articles/PMC4661391Test/

المؤلفون: Juan Miguel López del Amo, Ronald Frank, Bernd Reif, Marcus Fändrich, Björn Grüning, Stefan Günther, Jan Bieschke, Erich E. Wanker, Michael Schmidt, Franziska Schiele, Annett Boeddrich, Thomas Wiglenda, Qinwen Wang, Roger Anwyl, Rudi Lurz, Daniela Kleckers, Sigrid Schnoegl, Dominic M. Walsh, Ralf P. Friedrich, Martin Herbst

المصدر: Nature Chemical Biology; Vol 8
Nature Chemical Biology

مصطلحات موضوعية: Models, Molecular, Amyloid, Beta sheet, 010402 general chemistry, Fibril, Hippocampus, Synaptic Transmission, 01 natural sciences, Protein Structure, Secondary, 03 medical and health sciences, Protein structure, Microscopy, Electron, Transmission, Cell Line, Tumor, Oxazines, Humans, Amino Acid Sequence, Molecular Biology, Peptide sequence, 030304 developmental biology, 0303 health sciences, Chemistry, Fibrillogenesis, Long-term potentiation, Cell Biology, Small molecule, Peptide Fragments, 0104 chemical sciences, Biochemistry, Hydrophobic and Hydrophilic Interactions

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f30fcb247be102ca7b8ff9fa4541a40Test

المؤلفون: Anna Klukovits, Friedrich W. Herberg, Kornelia Hampel, Dmitry Kashin, Kerstin Zühlke, Judit Verli, Andrey C. da Costa Goncalves, Mangesh Joshi, Hannelore Haase, Martin W. Bergmann, Bernd Reif, Marta Dr. Szaszak, Dorothea Lorenz, Robert S. Kass, Dermot M.F. Cooper, Hans G. Genieser, Ingo Morano, Solveig Grossmann, Sabine Friedl, Bastian Zimmermann, Marie C. Moutty, Peter Schmieder, Frank Christian, Hendrikje Göttert, George S. Baillie, Frank Götz, Carolyn Vargas, Walter Rosenthal, Miles D. Houslay, Jens Furkert, Jens Peter von Kries, Róbert Gáspár, Claudia Noack, Stephan Drewianka, Debbie Willoughby, Enno Klussmann

المصدر: The Journal of Biological Chemistry
The journal of biological chemistry, 286: 9079-9096

مصطلحات موضوعية: Male, Allosteric regulation, Cyclic AMP (cAMP), Adenylate Cyclase (Adenylyl Cyclase), AKAP18, A Kinase Anchor Proteins, Biology, Biochemistry, Rats, Inbred WKY, Second Messenger Systems, Protein Phosphorylation, 03 medical and health sciences, Enzyme activator, AKAP150, 0302 clinical medicine, AKAP, Allosteric Regulation, Cyclic AMP, Myocyte, Animals, Protein phosphorylation, Myocytes, Cardiac, Protein kinase A, Molecular Biology, Protein Kinase Inhibitors, 030304 developmental biology, Heart Failure, 0303 health sciences, Protein Kinase A (PKA), Cell Biology, Yotiao, Cyclic AMP-Dependent Protein Kinases, Myocardial Contraction, 3. Good health, Cell biology, Rats, Enzyme Activation, Compartmentalization, Protein-Protein Interactions, Second messenger system, Chronic Disease, Signal Transduction, Compartmentalized Signaling, Signal transduction, 030217 neurology & neurosurgery

وصف الملف: text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524465e5c34273c7764a0932ea83b11aTest
http://europepmc.org/articles/PMC3058960Test

المؤلفون: Hans-Michael Zenn, Viola Popara, Christian Hundsrucker, Walter Rosenthal, Friedrich W. Herberg, Bernd Reif, Burkhard Wiesner, Mangesh Joshi, Enno Klussmann, Philipp Skroblin, Jenny Eichhorst, Frank Christian

المصدر: The journal of biological chemistry, 285: 5507-5521

مصطلحات موضوعية: Scaffold protein, A-kinase-anchoring protein, endocrine system, Amino Acid Motifs, Protein domain, A Kinase Anchor Proteins, Plasma protein binding, Biology, Biochemistry, Glycogen Synthase Kinase 3, Protein structure, GSK-3, Cell Line, Tumor, Humans, Molecular Biology, GSK3B, Glycogen Synthase Kinase 3 beta, Cell Biology, Cyclic AMP-Dependent Protein Kinases, Protein Structure, Tertiary, Evolution/Protein, Signal Transduction/Cyclic Nucleotides/Cyclic AMP, Signal Transduction/Protein Kinases/Serine/Threonine, Protein/Protein-Protein Interactions, Signal Transduction/Protein Kinases/Cyclic Nucleotide, Signal Transduction/Adapter Proteins, Signal Transduction/Protein Kinases, AKAP, Phosphorylation/Kinases/Serine-Threonine, Protein Multimerization, Signal Transduction, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c225b249a1b18fc54c2a0a0bbc1d7b39Test
https://doi.org/10.1074/jbc.m109.047944Test