المؤلفون: Matt J. Silver, Paula Dominguez-Salas, Daniela Handke, Andrew M. Prentice, Jörg Gromoll, Sophie E. Moore, Robert A. Waterland, Branwen J. Hennig, Anke Hinney, Joachim Spranger, Johannes Hebebrand, Frank L. Heppner, Lena Walzer, Anthony J. C. Fulford, Peter Kühnen, Susanna Wiegand, Heiko Krude, Carsten Grötzinger, Annette Grüters

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Pro-Opiomelanocortin, Physiology, Offspring, Medizin, Biology, Cohort Studies, 03 medical and health sciences, Missing heritability problem, Pregnancy, Genetic variation, Humans, Epigenetics, Melanocyte-Stimulating Hormones, Obesity, Allele, Molecular Biology, Alleles, Genetics, Body Weight, Genetic Variation, Cell Biology, Methylation, Sequence Analysis, DNA, Heritability, DNA Methylation, Middle Aged, Carbon, 030104 developmental biology, DNA methylation, Leukocytes, Mononuclear, CpG Islands, Female, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8993112223eb407813fb1897acb0a9e4Test
https://www.ncbi.nlm.nih.gov/pubmed/27568547Test

المؤلفون: Jessica Mühlhaus, Martin Klingenspor, Harald Brumm, S. Scherag, Johannes Hebebrand, Heike Biebermann, Anke Hinney, Susanna Wiegand, Florian Bolze, Heiko Krude, Annette Grüters

المصدر: Obesity. 20:1074-1081

مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, Nonsense mutation, Mutant, Medizin, Medicine (miscellaneous), Biology, Endocrinology, Humans, Obesity, Receptor, Gene, Genetics, Oxadiazoles, Nutrition and Dietetics, Wild type, Stop codon, Cell biology, Melanocortin 4 receptor, Aminoglycosides, Blood-Brain Barrier, Codon, Nonsense, Codon, Terminator, Receptor, Melanocortin, Type 4, Female, Signal transduction, Energy Metabolism, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7816d403e052f25779dfc52229e0869Test
https://doi.org/10.1038/oby.2011.202Test

المؤلفون: Eva Rettenbacher, Kurt Widhalm, Johannes Hebebrand, Heike Biebermann, Anke Hinney, Harald Brumm, Patrick Tarnow, Petra Ambrugger, Michael Schaefer, Annette Grüters, Anne Rediger, Gerd Krause, Gunnar Kleinau

المصدر: Obesity Facts. 1:155-162

مصطلحات موضوعية: Adult, Male, Models, Molecular, Heterozygote, Health (social science), Adolescent, Mutant, Transfection, Physiology (medical), Chlorocebus aethiops, Animals, Humans, Medicine, Obesity, Receptor, Genes, Dominant, COS cells, business.industry, Wild type, Hydrogen Bonding, Heterozygote advantage, Middle Aged, Cell biology, Transmembrane domain, Child, Preschool, COS Cells, Mutation, Mutation (genetic algorithm), Receptor, Melanocortin, Type 4, Original Article, Female, Signal transduction, business, Dimerization, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54e6a42c15827f45fdbf7c2bbab6c74Test
https://doi.org/10.1159/000138251Test

المؤلفون: Anne Müller, Carolin S. Hoefig, Maxi Cöster, Carolin Leonie Wienchol, Heiko Krude, Jens Mittag, Jessica Mühlhaus, Annette Grüters, Torsten Schöneberg, Heike Biebermann, Jaroslawna Meister, Juliane Dinter, Josef Köhrle, Gunnar Kleinau, Simon Friedrich Jacobi

المصدر: Journal of molecular endocrinology. 54(3)

مصطلحات موضوعية: MAPK/ERK pathway, Male, Mice, 129 Strain, Adrenergic receptor, Drug Evaluation, Preclinical, Gene Expression, GTP-Binding Protein alpha Subunits, Gi-Go, Receptors, G-Protein-Coupled, 3-Iodothyronamine, chemistry.chemical_compound, Islets of Langerhans, Norepinephrine, Endocrinology, Receptors, Adrenergic, alpha-2, TAAR1, Adrenergic alpha-2 Receptor Agonists, Thyronines, Glucose homeostasis, Animals, Humans, Receptor, Molecular Biology, G protein-coupled receptor, Chemistry, Cell biology, Mice, Inbred C57BL, Glucose, HEK293 Cells, Signal transduction, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa88e1dab741a73ddd0ec8e5dea8c33aTest
https://pubmed.ncbi.nlm.nih.gov/25878061Test

المؤلفون: Josef Köhrle, Silke Morin, Juliane Dinter, Gunnar Kleinau, Matthias Tschöp, Jessica Mühlhaus, Daniela Nürnberg, Heiko Krude, Chun-Xia Yi, Heike Biebermann, Torsten Schöneberg, Carolin Leonie Wienchol, Annette Grüters

المساهمون: AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Endocrinology

المصدر: PLoS ONE, 10(2). Public Library of Science
PLoS ONE
PLoS ONE 10:e0117774 (2015)
PLoS ONE, Vol 10, Iss 2, p e0117774 (2015)

مصطلحات موضوعية: medicine.medical_specialty, MAP Kinase Signaling System, G protein, lcsh:Medicine, Biology, Ligands, Cell Line, Receptors, G-Protein-Coupled, 3-Iodothyronamine, Mice, TAAR5, chemistry.chemical_compound, Internal medicine, TAAR1, Chlorocebus aethiops, Thyronines, medicine, Animals, Humans, lcsh:Science, Receptor, Trace amine-associated receptor, Mice, Knockout, Multidisciplinary, lcsh:R, Cell biology, Mice, Inbred C57BL, HEK293 Cells, Endocrinology, chemistry, COS Cells, Knockout mouse, lcsh:Q, Signal transduction, Signal Transduction, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48002c58423e84de29ceaa46a955327eTest
https://pure.amc.nl/en/publications/inverse-agonistic-action-of-3iodothyronamine-at-the-human-trace-amineassociated-receptor-5Test(b83ca6e9-def8-45a8-8648-1535f3db2a7f).html

المؤلفون: Annette Grüters, Anne Müller, Jana Fischer, Timo D. Müller, Heike Biebermann, Vera Knäuper, Gunnar Kleinau, Matthias H. Tschöp, Brinja Leinweber

المصدر: BMC Res. Notes 7:913 (2014)
BMC Research Notes

مصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, Short Report, Biology, Q1, General Biochemistry, Genetics and Molecular Biology, Receptors, G-Protein-Coupled, Mice, GTP-Binding Proteins, Constitutive activation, Extracellular, Enzyme-linked receptor, Animals, Humans, Inverse agonist, Amino Acid Sequence, GABBR2, GABBR1, Receptor, Signaling mechanism, G protein-coupled receptor, Medicine(all), G-protein coupled receptor 83, Binding Sites, Sequence Homology, Amino Acid, Biochemistry, Genetics and Molecular Biology(all), Cell Membrane, Antagonist, General Medicine, Protein Structure, Tertiary, Cell biology, HEK293 Cells, Biochemistry, COS Cells, Mutation, Mitogen-Activated Protein Kinases, Signal transduction, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe2753fb0136feea7d2d766e964f645Test
https://doi.org/10.1186/1756-0500-7-913Test

المؤلفون: Heiko Krude, Gunnar Kleinau, Carolin L. Piechowski, Chun-Xia Yi, Josef Köhrle, Annette Grüters, M. H. Tschöp, Daniela Nürnberg, Andrea M. Müller, Jessica Mühlhaus, Heike Biebermann, Juliane Dinter

المصدر: Experimental and Clinical Endocrinology & Diabetes. 122

مصطلحات موضوعية: MAPK/ERK pathway, Agonist, medicine.medical_specialty, medicine.drug_class, Endocrinology, Diabetes and Metabolism, General Medicine, Biology, Cell biology, 3-Iodothyronamine, chemistry.chemical_compound, Endocrinology, chemistry, TAAR1, Internal medicine, Internal Medicine, medicine, Inverse agonist, Signal transduction, Receptor, Trace amine-associated receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3a8525db8d5f66836b4e9d88966e1ecbTest
https://doi.org/10.1055/s-0034-1372013Test

المؤلفون: Heike Biebermann, Heiko Krude, Annette Grüters, Gunnar Kleinau, Susanne Neumann

المصدر: Endocrine reviews. 34(5)

مصطلحات موضوعية: endocrine system, endocrine system diseases, G protein, Protein Conformation, Endocrinology, Diabetes and Metabolism, Gene Expression, Reviews, Biology, Thyrotropin receptor, Endocrinology, GTP-binding protein regulators, GTP-Binding Proteins, Humans, Amino Acids, Receptor, G protein-coupled receptor, Binding Sites, Molecular Structure, Cell Membrane, Genetic Variation, Receptors, Thyrotropin, Thyroid Diseases, eye diseases, Cell biology, Phenotype, Biochemistry, Hormone receptor, Mutation, Signal transduction, hormones, hormone substitutes, and hormone antagonists, Hormone, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8eaa4e52c29e2b02cd9954261f81369Test
https://pubmed.ncbi.nlm.nih.gov/23645907Test

المؤلفون: Juliane Pratzka, Timo D. Müller, Heiko Krude, Matthias H. Tschöp, Annette Grüters, Carolin L. Piechowski, Anne Müller, Brian Finan, Gunnar Kleinau, Heike Biebermann

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e53347 (2013)
PLoS ONE 8:e53347 (2013)

مصطلحات موضوعية: Protein Conformation, Amino Acid Motifs, lcsh:Medicine, Gene Expression, Plasma protein binding, Signal transduction, Receptors, G-Protein-Coupled, Mice, Molecular cell biology, Chlorocebus aethiops, Signaling in Cellular Processes, Membrane Receptor Signaling, Receptor, lcsh:Science, Second Messenger System, Multidisciplinary, COS cells, Mechanisms of Signal Transduction, Neurotransmitter Receptor Signaling, Signaling cascades, Ligand (biochemistry), Hormone Receptor Signaling, cAMP signaling cascade, Cell biology, Molecular Docking Simulation, Biochemistry, COS Cells, Polyphosphoinositide signaling cascade, Protein Binding, Research Article, G protein, Adenylyl Cyclase Signaling Pathway, chemistry.chemical_element, Zinc, Biology, Signaling Pathways, Chlorides, Genetic Mutation, Genetics, Animals, Humans, Adenylyl cyclase signaling cascade, G protein-coupled receptor, Binding Sites, lcsh:R, Cell Membrane, G-Protein Signaling, HEK293 Cells, chemistry, Zinc Compounds, Mutagenesis, Mutation, lcsh:Q, Protein Multimerization

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3e507a7115158338c30723dc58e528Test
https://pubmed.ncbi.nlm.nih.gov/23335960Test

المؤلفون: Eva K. Wirth, Marc Klein, Annette Grüters, Ulrich Schweizer, Doreen Braun, Franziska Wohlgemuth, Nathalie Reix, Josef Köhrle

المساهمون: Institut fur Experimentelle Endokrinologie, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]

المصدر: Biochemical Journal
Biochemical Journal, Portland Press, 2011, 439 (2), pp.249-255. ⟨10.1042/BJ20110759⟩

مصطلحات موضوعية: Thyroid Hormones, medicine.medical_specialty, Amino Acid Transport System y+, Blotting, Western, Biology, Polymerase Chain Reaction, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Neutral amino acid transport, medicine, Animals, Amino acid transporter, Amino Acid Metabolism, Inborn Errors, Molecular Biology, DNA Primers, 030304 developmental biology, Mice, Knockout, chemistry.chemical_classification, Monocarboxylate transporter, 0303 health sciences, Base Sequence, Fusion Regulatory Protein 1, Light Chains, Thyroid, Brain, Life Sciences, Transporter, Cell Biology, medicine.disease, Immunohistochemistry, Amino acid, Mice, Inbred C57BL, Endocrinology, medicine.anatomical_structure, chemistry, Aminoaciduria, biology.protein, 030217 neurology & neurosurgery, Signal Transduction, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7ac0bddd6a4b0a4f4db15785bcee5aTest
https://hal.archives-ouvertes.fr/hal-00628667/file/PEER_stage2_10.1042%2FBJ20110759.pdfTest