المؤلفون: Ling Chen, Ya Wang, Guoxi Li, Qi Wan, Tingting Di, Huanxian Chang, Wenfeng Yu, Xianying Zeng

المصدر: Neurobiology of Disease, Vol 127, Iss, Pp 350-361 (2019)

مصطلحات موضوعية: 0301 basic medicine, BSCL2, Tau protein, Hyperphosphorylation, tau Proteins, Tau phosphorylation, Hippocampus, Protein Aggregation, Pathological, Seipin, lcsh:RC321-571, Congenital generalized lipodystrophy, 03 medical and health sciences, Mice, 0302 clinical medicine, GTP-Binding Protein gamma Subunits, Peroxisome proliferator-activated receptor-γ (PPARγ), medicine, Animals, Phosphorylation, Protein kinase B, Mammalian target of rapamycin (mTOR), lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, PI3K/AKT/mTOR pathway, Mice, Knockout, Neurons, Glycogen Synthase Kinase 3 beta, biology, Chemistry, TOR Serine-Threonine Kinases, GSK3β, Insulin resistance, medicine.disease, Axons, Cell biology, PPAR gamma, 030104 developmental biology, Neurology, biology.protein, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e9c26c8af25986e1d0768233a2ccb9Test
http://www.sciencedirect.com/science/article/pii/S0969996119300762Test

المؤلفون: Yukari Kyumoto-Nakamura, Kento Nishida, Soichiro Sonoda, Sara Murata, Shion Hama, Toshio Kukita, Takayoshi Yamaza, Haruyoshi Yamaza, Kazuaki Nonaka, Yosuke Tanaka, Norihisa Uehara

المصدر: Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-12 (2018)

مصطلحات موضوعية: Male, 0301 basic medicine, Small interfering RNA, Bone Regeneration, Cell, Medicine (miscellaneous), Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Osteogenesis, lcsh:QD415-436, Phosphorylation, lcsh:R5-920, biology, Chemistry, Cell Differentiation, Phosphoinositide 3 kinase (PI3K), Up-Regulation, Cell biology, medicine.anatomical_structure, Molecular Medicine, Stem cell, lcsh:Medicine (General), Signal Transduction, Scaffold-free spheroidal calcified construct, Stem cells from apical papilla (SCAP), Biochemistry, Genetics and Molecular Biology (miscellaneous), lcsh:Biochemistry, Young Adult, 03 medical and health sciences, Spheroids, Cellular, medicine, Animals, Humans, Mammalian target of rapamycin (mTOR), Dental Papilla, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, Phosphoinositide 3-kinase, Research, AKT, Multipotent Stem Cells, Regeneration (biology), Mesenchymal stem cell, Mesenchymal Stem Cells, 030206 dentistry, Cell Biology, Dentinogenesis, 030104 developmental biology, Dentin, biology.protein, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da87115e32aceab171d86993f9bb56bTest
https://doi.org/10.1186/s13287-018-1077-9Test

المؤلفون: José L. Quiles, Ángel J. De la Rosa, José L. Mauriz, Francisco J. Padillo, Raúl González, José M. Fuentes, Jesús de la Cruz, Javier González-Gallego, Elena Navarro-Villarán, Raquel Ordóñez, L.M. Marín-Gómez, Jordi Muntané, Mario Rodríguez-Arribas, María A. Rodríguez-Hernández, J.M. Álamo-Martínez, Paloma Gallego, Laura Contreras, José A Del Campo

المساهمون: Universidad de Sevilla. Departamento de Genética

المصدر: idUS. Depósito de Investigación de la Universidad de Sevilla
instname

مصطلحات موضوعية: 0301 basic medicine, Sorafenib, Cell signaling, autophagy, Physiology, Clinical Biochemistry, Apoptosis, 03 medical and health sciences, Mice, 0302 clinical medicine, Downregulation and upregulation, Autophagy, medicine, Biomarkers, Tumor, Animals, Humans, Bcl-2, Protein kinase A, Protein kinase B, PI3K/AKT/mTOR pathway, Chemistry, Caspase 3, mammalian target of rapamycin (mTOR), Liver Neoplasms, apoptosis, JNK Mitogen-Activated Protein Kinases, Cell Biology, Hep G2 Cells, Endoplasmic Reticulum Stress, 5′AMP-activated protein kinase (AMPK), Xenograft Model Antitumor Assays, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Unfolded protein response, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Transcription Factor CHOP, medicine.drug, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13faddb9a0c020090635a3ed453ddd5eTest
https://hdl.handle.net/10668/12863Test

المؤلفون: Ji Miao, Sudha B. Biddinger, Ivana Semova, Anthony N. Hollenberg, Hong Kang, Matthew D. Hirschey, David Masson, Yue Hu, Satyapal Chahar, Xiaowei Sun

المساهمون: Division of Endocrinology, Children's Hospital Boston, Harvard Medical School, Harvard Medical School [Boston] ( HMS ), Beth Israel Deaconess Medical Center, Lipides - Nutrition - Cancer [Dijon - U1231] ( LNC ), Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Duke University Medical Center

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2018, 293 (6), pp.2006-2014. 〈http://www.jbc.org/content/293/6/2006.longTest〉. 〈10.1074/jbc.M117.782557〉

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biochemistry, metabolic syndrome, fructose, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Internal medicine, Gene expression, medicine, Animals, glucose, Molecular Biology, [ SDV.BBM ] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Triglycerides, lipogenesis, Mice, Knockout, Fatty liver, dyslipidemia, mammalian target of rapamycin (mTOR), Lipid metabolism, Fructose, Cell Biology, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Metabolism, chemistry, Gene Expression Regulation, Liver, Lipogenesis, Metabolic syndrome, Signal transduction, biological phenomena, cell phenomena, and immunity, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0151552b633fb1a9d27448adf7dd3bTest
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01730773Test

المؤلفون: Paola Muti, Gregory R. Steinberg, Bruce E. Kemp, Andrew J. O'Brien, Vanessa P. Houde, Linda Villani, Theodoros Tsakiridis, Giovanni Blandino, Sandra Galic, Lindsay A. Broadfield

مصطلحات موضوعية: Male, Lung Neoplasms, Sodium Salicylate, AMP-Activated Protein Kinases, Biochemistry, chemistry.chemical_compound, Mice, AMP-activated protein kinase, Mice, Knockout, Aspirin, biology, Anti-Inflammatory Agents, Non-Steroidal, mammalian target of rapamycin (mTOR), Drug Synergism, Metformin, Neoplasm Proteins, Lipogenesis, Female, medicine.drug, acetyl-CoA carboxylase (ACC), medicine.medical_specialty, Cell Survival, aspirin, proliferation, fatty acids, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Hypoglycemic Agents, Protein kinase A, Molecular Biology, Sodium salicylate, Fatty acid synthesis, Binding Sites, AMPK, Prostatic Neoplasms, cholesterol, Cell Biology, Fibroblasts, Embryo, Mammalian, Enzyme Activation, Endocrinology, chemistry, biology.protein, Cancer research, 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase, Acetyl-CoA Carboxylase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fa08a800d2106d31457a94d70f7df9Test
https://acuresearchbank.acu.edu.au/item/8825v/salicylate-activates-ampk-and-synergizes-with-metformin-to-reduce-the-survival-of-prostate-and-lung-cancer-cells-ex-vivo-through-inhibition-of-de-novo-lipogenesisTest

المؤلفون: Suhua Zhu, Qing-Ping Li, Xiaowei Wu, Hong-Yi Zhu, Liang Hu, Maojuan Hao

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 3; Pages: 614
International Journal of Molecular Sciences, Vol 18, Iss 3, p 614 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, Nitric Oxide Synthase Type I, AMP-Activated Protein Kinases, lcsh:Chemistry, Mice, Ischemic Postconditioning, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, TOR Serine-Threonine Kinases, mammalian target of rapamycin (mTOR), General Medicine, Mitochondria, Computer Science Applications, Cell biology, Reperfusion Injury, cardiovascular system, Signal Transduction, medicine.drug, autophagy, adenosine monophosphate-activated protein kinase (AMPK), medicine.medical_specialty, Article, Catalysis, Cell Line, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, Animals, Physical and Theoretical Chemistry, Protein kinase A, ischemic postconditioning (IPostC), ischemia/reperfusion, neuronal nitric oxide synthase (nNOS), Molecular Biology, PI3K/AKT/mTOR pathway, Reactive oxygen species, Myocardium, Organic Chemistry, Autophagy, AMPK, medicine.disease, Adenosine, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, chemistry, Apoptosis, Reperfusion injury

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b699fa81934a03619a9805f733e92b6dTest
https://doi.org/10.3390/ijms18030614Test