التفاصيل البيبلوغرافية
| العنوان: |
Complications of intravascular catheters in ICU: definitions, incidence and severity. A randomized controlled trial comparing usual transparent dressings versus new-generation dressings (the ADVANCED study). |
| المؤلفون: |
Günther, Silvia, Schwebel, Carole, Hamidfar-Roy, Rebecca, Bonadona, Agnès, Lugosi, Maxime, Ara-Somohano, Claire, Minet, Clémence, Potton, Leïla, Cartier, Jean-Charles, Vésin, Aurelien, Chautemps, Magalie, Styfalova, Lenka, Ruckly, Stephane, Timsit, Jean-François, Günther, Silvia Calviño, Bonadona, Agnès, Minet, Clémence, Potton, Leïla, Vésin, Aurelien, Timsit, Jean-François |
| المصدر: |
Intensive Care Medicine; Nov2016, Vol. 42 Issue 11, p1753-1765, 13p |
| مصطلحات موضوعية: |
CENTRAL venous catheters, ARTERIAL catheters, DIALYSIS catheters, DELPHI method, RANDOMIZED controlled trials, CATHETERS, CLINICAL trials, COMPARATIVE studies, LENGTH of stay in hospitals, INTENSIVE care units, INTRAVENOUS catheterization, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, NONPARAMETRIC statistics, RESEARCH, SURGICAL dressings, THROMBOSIS, TIME, EVALUATION research, DISEASE incidence, SEVERITY of illness index, MEDICAL equipment reliability, CATHETER-related infections |
| مستخلص: |
Purpose: To describe all post-insertion complications involving most used intravascular access, and to determine whether the use of a new-generation transparent dressing (3M™ IV Advanced) might reduce their number and impact on ICU patient outcomes.Methods: Patients older than 18, with an expected length of stay ≥48 h and requiring at least one central venous catheter (CVC), arterial catheter (AC), haemodialysis catheter (HDC), pulmonary arterial catheters (PAC) or peripheral venous catheter (PVC) were randomized into two groups: a new-generation transparent dressing, or the hospital's classical transparent dressing, and were followed daily for any infectious and non-infectious complications. Complications were graduated for severity by an independent international multicentre multidisciplinary panel of practitioners using a Delphi process.Results: We included 628 patients, 2214 catheters (873 PVCs, 630 CVCs, 512 ACs and 199 HDCs and PACs) and 4836 dressings. Overall incidence rate was of 60.9/1000 catheter-days. The most common complication was dysfunction (34.6/1000 catheter-days), mainly for PVCs (16/1000 catheter-days) and ACs (12.9/1000 catheter-days). Infectious complications incidence rate in CVCs and ACs was of 14.5/1000, mostly due to colonization (14.2/1000 catheter-days). Thrombosis incidence was of 3.8/1000 catheter-days with severe and very severe complications in 16 cases (1.8/1000 catheter-days) and one thrombosis-related death. 3M™ IV Advanced dressing did not decrease the rate of catheters with at least a minor complication [57.37/1000 vs. 57.52/1000 catheter-days, HR 1.03, CI (0.84-1.27), p = 0.81]. Incidence rates for each single complication remained equivalent: infectious [HR 0.93 (0.62-1.40), p = 0.72], deep thrombosis [HR 0.90 (0.39-2.06), p = 0.80], extravasation and phlebitis [HR 1.40 (0.69-2.82), p = 0.35], accidental removal [1.07 (0.56-2.04), p = 0.84] and dysfunction [HR 1.04 (0.80-1.35), p = 0.79].Conclusion: The ADVANCED study showed the overall risk of complications to intravascular catheters in ICU patients being dysfunction, infection and thrombosis. The 3M™ IV Advanced dressing did not decrease complication rates as compared to standard dressings. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
