التفاصيل البيبلوغرافية
| العنوان: |
Association Between Enterovirus Infection and Type 1 Diabetes Risk: A Meta-Analysis of 38 Case-Control Studies. |
| المؤلفون: |
Wang, Kan, Ye, Fei, Chen, Yong, Xu, Jianxin, Zhao, Yufang, Wang, Yeping, Lan, Tian |
| المصدر: |
Frontiers in Endocrinology; 9/7/2021, Vol. 12, p1-9, 9p |
| مصطلحات موضوعية: |
ENTEROVIRUS diseases, TYPE 1 diabetes, CASE-control method, ODDS ratio |
| مصطلحات جغرافية: |
NORTH America |
| مستخلص: |
Objective: The association between enterovirus infection and type 1 diabetes (T1D) is controversial, and this meta-analysis aimed to explore the correlation. Methods: PubMed, Embase, Web of Science, and Cochrane Database were searched from inception to April 2020. Studies were included if they could provide sufficient information to calculate odds ratios and 95% confidence intervals. All analyses were performed using STATA 15.1. Results: Thirty-eight studies, encompassing 5921 subjects (2841 T1D patients and 3080 controls), were included. The pooled analysis showed that enterovirus infection was associated with T1D (P < 0.001). Enterovirus infection was correlated with T1D in the European (P < 0.001), African (P = 0.002), Asian (P = 0.001), Australian (P = 0.011), and Latin American (P = 0.002) populations, but no conclusion could be reached for North America. The association between enterovirus infection and T1D was detected in blood and tissue samples (both P < 0.001); no association was found in stool samples. Conclusion: Our findings suggest that enterovirus infection is associated with T1D. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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