المؤلفون: Gerard Temprano‐Sagrera, Colleen M. Sitlani, William P. Bone, Miguel Martin‐Bornez, Benjamin F. Voight, Alanna C. Morrison, Scott M. Damrauer, Paul S. de Vries, Nicholas L. Smith, Maria Sabater‐Lleal, Abbas Dehghan, Adam S Heath, Alanna C Morrison, Alex P Reiner, Andrew Johnson, Anne Richmond, Annette Peters, Astrid van Hylckama Vlieg, Barbara McKnight, Bruce M Psaty, Caroline Hayward, Cavin Ward‐Caviness, Christopher O’Donnell, Daniel Chasman, David P Strachan, David A Tregouet, Dennis Mook‐Kanamori, Dipender Gill, Florian Thibord, Folkert W Asselbergs, Frank W.G. Leebeek, Frits R Rosendaal, Gail Davies, Georg Homuth, Gerard Temprano, Harry Campbell, Herman A Taylor, Jan Bressler, Jennifer E Huffman, Jerome I Rotter, Jie Yao, James F Wilson, Joshua C Bis, Julie M Hahn, Karl C Desch, Kerri L Wiggins, Laura M Raffield, Lawrence F Bielak, Lisa R Yanek, Marcus E Kleber, Martina Mueller, Maryam Kavousi, Massimo Mangino, Melissa Liu, Michael R Brown, Matthew P Conomos, Min‐A Jhun, Ming‐Huei Chen, Moniek P.M. de Maat, Nathan Pankratz, Nicholas L Smith, Patricia A Peyser, Paul Elliot, Paul S de Vries, Peng Wei, Philipp S Wild, Pierre E Morange, Pim van der Harst, Qiong Yang, Ngoc‐Quynh Le, Riccardo Marioni, Ruifang Li, Scott M Damrauer, Simon R Cox, Stella Trompet, Stephan B Felix, Uwe Völker, Weihong Tang, Wolfgang Koenig, J. Wouter Jukema, Xiuqing Guo, Sara Lindstrom, Lu Wang, Erin N Smith, William Gordon, Mariza de Andrade, Jennifer A Brody, Jack W Pattee, Jeffrey Haessler, Ben M Brumpton, Daniel I Chasman, Pierre Suchon, Constance Turman, Marine Germain, James MacDonald, Sigrid K Braekkan, Sebastian M Armasu, Rabecca D Jackson, Jonas B Nielsen, Franco Giulianini, Marja K Puurunen, Manal Ibrahim, Susan R Heckbert, Theo K Bammler, Kelly A Frazer, Bryan M McCauley, Kent Taylor, James S Pankow, Alexander P Reiner, Maiken E Gabrielsen, Jean‐François Deleuze, Chris J O’Donnell, Jihye Kim, Peter Kraft, John‐Bjarne Hansen, John A Heit, Charles Kooperberg, Kristian Hveem, Paul M Ridker, Pierre‐Emmanuel Morange, Andrew D Johnson, Christopher Kabrhel, David‐Alexandre Trégouët, Rainer Malik, Ganesh Chauhan, Matthew Traylor, Muralidharan Sargurupremraj, Yukinori Okada, Aniket Mishra, Loes Rutten‐Jacobs, Anne‐Katrin Giese, Sander W van der Laan, Solveig Gretarsdottir, Christopher D Anderson, Michael Chong, Hieab HH Adams, Tetsuro Ago, Peter Almgren, Philippe Amouyel, Hakan Ay, Traci M Bartz, Oscar R Benavente, Steve Bevan, Giorgio B Boncoraglio, Robert D Brown, Adam S Butterworth, Caty Carrera, Cara L Carty, Wei‐Min Chen, John W Cole, Adolfo Correa, Ioana Cotlarciuc, Carlos Cruchaga, John Danesh, Paul IW de Bakker, Anita L DeStefano, Marcel den Hoed, Qing Duan, Stefan T Engelter, Guido J Falcone, Rebecca F Gottesman, Raji P Grewal, Vilmundur Gudnason, Stefan Gustafsson, Tamara B Harris, Ahamad Hassan, Aki S Havulinna, Elizabeth G Holliday, George Howard, Fang‐Chi Hsu, Hyacinth I Hyacinth, M Arfan Ikram, Erik Ingelsson, Marguerite R Irvin, Xueqiu Jian, Jordi Jiménez‐Conde, Julie A Johnson, J Wouter Jukema, Masahiro Kanai, Keith L Keene, Brett M Kissela, Dawn O Kleindorfer, Michiaki Kubo, Leslie A Lange, Carl D Langefeld, Claudia Langenberg, Lenore J Launer, Jin‐Moo Lee, Robin Lemmens, Didier Leys, Cathryn M Lewis, Wei‐Yu Lin, Arne G Lindgren, Erik Lorentzen, Patrik K Magnusson, Jane Maguire, Ani Manichaikul, Patrick F McArdle, James F Meschia, Braxton D Mitchell, Thomas H Mosley, Michael A Nalls, Toshiharu Ninomiya, Martin J O’Donnell, Sara L Pulit, Kristiina Rannikmäe, Kathryn M Rexrode, Kenneth Rice, Stephen S Rich, Natalia S Rost, Peter M Rothwell, Tatjana Rundek, Ralph L Sacco, Saori Sakaue, Michele M Sale, Veikko Salomaa, Bishwa R Sapkota, Reinhold Schmidt, Carsten O Schmidt, Ulf Schminke, Pankaj Sharma, Agnieszka Slowik, Cathie LM Sudlow, Christian Tanislav, Turgut Tatlisumak, Kent D Taylor, Vincent NS Thijs, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Steffen Tiedt, Christophe Tzourio, Cornelia M van Duijn, Matthew Walters, Nicholas J Wareham, Sylvia Wassertheil‐Smoller, James G Wilson, Salim Yusuf, Najaf Amin, Hugo S Aparicio, Donna K Arnett, John Attia, Alexa S Beiser, Claudine Berr, Julie E Buring, Mariana Bustamante, Valeria Caso, Yu‐Ching Cheng, Seung Hoan Choi, Ayesha Chowhan, Natalia Cullell, Jean‐François Dartigues, Hossein Delavaran, Pilar Delgado, Marcus Dörr, Gunnar Engström, Ian Ford, Wander S Gurpreet, Anders Hamsten, Laura Heitsch, Atsushi Hozawa, Laura Ibanez, Andreea Ilinca, Martin Ingelsson, Motoki Iwasaki, Rebecca D Jackson, Katarina Jood, Pekka Jousilahti, Sara Kaffashian, Lalit Kalra, Masahiro Kamouchi, Takanari Kitazono, Olafur Kjartansson, Manja Kloss, Peter J Koudstaal, Jerzy Krupinski, Daniel L Labovitz, Cathy C Laurie, Christopher R Levi, Linxin Li, Lars Lind, Cecilia M Lindgren, Vasileios Lioutas, Yong Mei Liu, Oscar L Lopez, Hirata Makoto, Nicolas Martinez‐Majander, Koichi Matsuda, Naoko Minegishi, Joan Montaner, Andrew P Morris, Elena Muiño, Martina Müller‐Nurasyid, Bo Norrving, Soichi Ogishima, Eugenio A Parati, Leema Reddy Peddareddygari, Nancy L Pedersen, Joanna Pera, Markus Perola, Alessandro Pezzini, Silvana Pileggi, Raquel Rabionet, Iolanda Riba‐Llena, Marta Ribasés, Jose R Romero, Jaume Roquer, Anthony G Rudd, Antti‐Pekka Sarin, Ralhan Sarju, Chloe Sarnowski, Makoto Sasaki, Claudia L Satizabal, Mamoru Satoh, Naveed Sattar, Norie Sawada, Gerli Sibolt, Ásgeir Sigurdsson, Albert Smith, Kenji Sobue, Carolina Soriano‐Tárraga, Tara Stanne, O Colin Stine, David J Stott, Konstantin Strauch, Takako Takai, Hideo Tanaka, Kozo Tanno, Alexander Teumer, Liisa Tomppo, Nuria P Torres‐Aguila, Emmanuel Touze, Shoichiro Tsugane, Andre G Uitterlinden, Einar M Valdimarsson, Sven J van der Lee, Henry Völzke, Kenji Wakai, David Weir, Stephen R Williams, Charles DA Wolfe, Quenna Wong, Huichun Xu, Taiki Yamaji, Dharambir K Sanghera, Olle Melander, Christina Jern, Daniel Strbian, Israel Fernandez‐Cadenas, W T Longstreth, Arndt Rolfs, Jun Hata, Daniel Woo, Jonathan Rosand, Guillaume Pare, Jemma C Hopewell, Danish Saleheen, Kari Stefansson, Bradford B Worrall, Steven J Kittner, Sudha Seshadri, Myriam Fornage, Hugh S Markus, Joanna MM Howson, Yoichiro Kamatani, Stephanie Debette, Martin Dichgans

المساهمون: VU University medical center

المصدر: Temprano-Sagrera, G, Sitlani, C M, Bone, W P, Martin-Bornez, M, Voight, B F, Morrison, A C, Damrauer, S M, de Vries, P S, Smith, N L, Sabater-Lleal, M, Dehghan, A, Heath, A S, Morrison, A C, Reiner, A P, Johnson, A, Richmond, A, Peters, A, van Hylckama Vlieg, A, McKnight, B, Psaty, B M, Hayward, C, Ward-Caviness, C, O’Donnell, C, Chasman, D I, Strachan, D P, Trégouët, D A, Mook-Kanamori, D, Gill, D, Thibord, F, Asselbergs, F W, Leebeek, F W G, Rosendaal, F R, Davies, G, Homuth, G, Temprano, G, Campbell, H, Taylor, H A, Bressler, J, Huffman, J E, Rotter, J I, Yao, J, Wilson, J F, Bis, J C, Hahn, J M, Desch, K C, Wiggins, K L, Raffield, L M, Bielak, L F, Yanek, L R, Kleber, M E, Sabater-Lleal, M, Mueller, M, Kavousi, M, Mangino, M, Liu, M, Brown, M R, Conomos, M P, Jhun, M A, Chen, M H, de Maat, M P M, Pankratz, N, Smith, N L, Peyser, P A, Elliot, P, de Vries, P S, Wei, P, Wild, P S, Morange, P E, van der Harst, P, Yang, Q, Le, N Q, Marioni, R, Li, R, Damrauer, S M, Cox, S R, Trompet, S, Felix, S B, Völker, U, Tang, W, Koenig, W, Jukema, J W, Guo, X, Lindstrom, S, Wang, L, Smith, E N, Gordon, W, van Hylckama Vlieg, A, de Andrade, M, Brody, J A, Pattee, J W, Haessler, J, Brumpton, B M, Chasman, D I, Suchon, P, Chen, M H, Turman, C, Germain, M, Wiggins, K L, MacDonald, J, Braekkan, S K, Armasu, S M, Pankratz, N, Jackson, R D, Nielsen, J B, Giulianini, F, Puurunen, M K, Ibrahim, M, Heckbert, S R, Bammler, T K, Frazer, K A, McCauley, B M, Taylor, K D, Pankow, J S, Reiner, A P, Gabrielsen, M E, Deleuze, J F, O’Donnell, C J, Kim, J, McKnight, B, Kraft, P, Hansen, J B, Rosendaal, F R, Heit, J A, Psaty, B M, Tang, W, Kooperberg, C, Hveem, K, Ridker, P M, Morange, P E, Johnson, A, Kabrhel, C, Trégouët, D A, Smith, N L, Malik, R, Chauhan, G, Traylor, M, Sargurupremraj, M, Okada, Y, Mishra, A, Rutten-Jacobs, L, Giese, A K, van der Laan, S W, Gretarsdottir, S, Anderson, C D, Chong, M, Adams, H H H, Ago, T, Almgren, P, Amouyel, P, Ay, H, Bartz, T M, Benavente, O R, Bevan, S, Boncoraglio, G B, Brown, R D, Butterworth, A S, Carrera, C, Carty, C L, Chasman, D I, Chen, W M, Cole, J W, Correa, A, Cotlarciuc, I, Cruchaga, C, Danesh, J, de Bakker, P I W, DeStefano, A L, den Hoed, M, Duan, Q, Engelter, S T, Falcone, G J, Gottesman, R F, Grewal, R P, Gudnason, V, Gustafsson, S, Haessler, J, Harris, T B, Hassan, A, Havulinna, A S, Heckbert, S R, Holliday, E G, Howard, G, Hsu, F C, Hyacinth, H I, Arfan Ikram, M, Ingelsson, E, Irvin, M R, Jian, X, Jiménez-Conde, J, Johnson, J A, Jukema, J W, Kanai, M, Keene, K L, Kissela, B M, Kleindorfer, D O, Kooperberg, C, Kubo, M, Lange, L A, Langefeld, C D, Langenberg, C, Launer, L J, Lee, J M, Lemmens, R, Leys, D, Lewis, C M, Lin, W Y, Lindgren, A G, Lorentzen, E, Magnusson, P K, Maguire, J, Manichaikul, A, McArdle, P F, Meschia, J F, Mitchell, B D, Mosley, T H, Nalls, M A, Ninomiya, T, O’Donnell, M J, Psaty, B M, Pulit, S L, Rannikmäe, K, Reiner, A P, Rexrode, K M, Rice, K, Rich, S S, Ridker, P M, Rost, N S, Rothwell, P M, Rotter, J I, Rundek, T, Sacco, R L, Sakaue, S, Sale, M M, Salomaa, V, Sapkota, B R, Schmidt, R, Schmidt, C O, Schminke, U, Sharma, P, Slowik, A, Sudlow, C L M, Tanislav, C, Tatlisumak, T, Taylor, K D, Thijs, V N S, Thorleifsson, G, Thorsteinsdottir, U, Tiedt, S, Trompet, S, Tzourio, C, van Duijn, C M, Walters, M, Wareham, N J, Wassertheil-Smoller, S, Wilson, J F, Wiggins, K L, Yang, Q, Yusuf, S, Amin, N, Aparicio, H S, Arnett, D K, Attia, J, Beiser, A S, Berr, C, Buring, J E, Bustamante, M, Caso, V, Cheng, Y C, Hoan Choi, S, Chowhan, A, Cullell, N, Dartigues, J F, Delavaran, H, Delgado, P, Dörr, M, Engström, G, Ford, I, Gurpreet, W S, Hamsten, A, Heitsch, L, Hozawa, A, Ibanez, L, Ilinca, A, Ingelsson, M, Iwasaki, M, Jackson, R D, Jood, K, Jousilahti, P, Kaffashian, S, Kalra, L, Kamouchi, M, Kitazono, T, Kjartansson, O, Kloss, M, Koudstaal, P J, Krupinski, J, Labovitz, D L, Laurie, C C, Levi, C R, Li, L, Lind, L, Lindgren, C M, Lioutas, V, Mei Liu, Y, Lopez, O L, Makoto, H, Martinez-Majander, N, Matsuda, K, Minegishi, N, Montaner, J, Morris, A P, Muiño, E, Müller-Nurasyid, M, Norrving, B, Ogishima, S, Parati, E A, Reddy Peddareddygari, L, Pedersen, N L, Pera, J, Perola, M, Pezzini, A, Pileggi, S, Rabionet, R, Riba-Llena, I, Ribasés, M, Romero, J R, Roquer, J, Rudd, A G, Sarin, A P, Sarju, R, Sarnowski, C, Sasaki, M, Satizabal, C L, Satoh, M, Sattar, N, Sawada, N, Sibolt, G, Sigurdsson, Á, Smith, A, Sobue, K, Soriano-Tárraga, C, Stanne, T, Colin Stine, O, Stott, D J, Strauch, K, Takai, T, Tanaka, H, Tanno, K, Teumer, A, Tomppo, L, Torres-Aguila, N P, Touze, E, Tsugane, S, Uitterlinden, A G, Valdimarsson, E M, van der Lee, S J, Völzke, H, Wakai, K, Weir, D, Williams, S R, Wolfe, C D A, Wong, Q, Xu, H, Yamaji, T, Sanghera, D K, Melander, O, Jern, C, Strbian, D, Fernandez-Cadenas, I, Longstreth, W T, Rolfs, A, Hata, J, Woo, D, Rosand, J, Pare, G, Hopewell, J C, Saleheen, D, Stefansson, K, Worrall, B B, Kittner, S J, Seshadri, S, Fornage, M, Markus, H S, Howson, J M M, Kamatani, Y, Debette, S & Dichgans, M 2022, ' Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations ', Journal of Thrombosis and Haemostasis, vol. 20, no. 6, pp. 1331-1349 . https://doi.org/10.1111/jth.15698Test
Temprano-Sagrera, G, Sitlani, C M, Bone, W P, Martin-Bornez, M, Voight, B F, Morrison, A C, Damrauer, S M, de Vries, P S, Smith, N L, Sabater-Lleal, M, Dehghan, A, Heath, A S, Morrison, A C, Reiner, A P, Johnson, A, Richmond, A, Peters, A, van Hylckama Vlieg, A, McKnight, B, Psaty, B M, Hayward, C, Ward-Caviness, C, O’Donnell, C, Chasman, D, Strachan, D P, Tregouet, D A, Mook-Kanamori, D, Gill, D, Thibord, F, Asselbergs, F W, Leebeek, F W G, Rosendaal, F R, Davies, G, Homuth, G, Temprano, G, Campbell, H, Taylor, H A, Bressler, J, Huffman, J E, Rotter, J I, Yao, J, Wilson, J F, Bis, J C, Hahn, J M, Desch, K C, Wiggins, K L, Raffield, L M, Bielak, L F, Yanek, L R, Kleber, M E, Sabater-Lleal, M, Mueller, M, Kavousi, M, Mangino, M, Liu, M, Brown, M R, Conomos, M P, Jhun, M-A, Chen, M-H, de Maat, M P M, Pankratz, N, Smith, N L, Peyser, P A, Elliot, P, de Vries, P S, Wei, P, Wild, P S, Morange, P E, van der Harst, P, Yang, Q, le, N-Q, Marioni, R, Li, R, Damrauer, S M, Cox, S R, Trompet, S, Felix, S B, Völker, U, Tang, W, Koenig, W, Jukema, J W, Guo, X, Lindstrom, S, Wang, L, Smith, E N, Gordon, W, van Hylckama Vlieg, A, de Andrade, M, Brody, J A, Pattee, J W, Haessler, J, Brumpton, B M, Chasman, D I, Suchon, P, Chen, M-H, Turman, C, Germain, M, Wiggins, K L, MacDonald, J, Braekkan, S K, Armasu, S M, Pankratz, N, Jackson, R D, Nielsen, J B, Giulianini, F, Puurunen, M K, Ibrahim, M, Heckbert, S R, Bammler, T K, Frazer, K A, McCauley, B M, Taylor, K, Pankow, J S, Reiner, A P, Gabrielsen, M E, Deleuze, J-F, O’Donnell, C J, Kim, J, McKnight, B, Kraft, P, Hansen, J-B, Rosendaal, F R, Heit, J A, Psaty, B M, Tang, W, Kooperberg, C, Hveem, K, Ridker, P M, Morange, P-E, Johnson, A D, Kabrhel, C, Trégouët, D-A, Smith, N L, Malik, R, Chauhan, G, Traylor, M, Sargurupremraj, M, Okada, Y, Mishra, A, Rutten-Jacobs, L, Giese, A-K, van der Laan, S W, Gretarsdottir, S, Anderson, C D, Chong, M, Adams, H H H, Ago, T, Almgren, P, Amouyel, P, Ay, H, Bartz, T M, Benavente, O R, Bevan, S, Boncoraglio, G B, Brown, R D, Butterworth, A S, Carrera, C, Carty, C L, Chasman, D I, Chen, W-M, Cole, J W, Correa, A, Cotlarciuc, I, Cruchaga, C, Danesh, J, de Bakker, P I W, DeStefano, A L, den Hoed, M, Duan, Q, Engelter, S T, Falcone, G J, Gottesman, R F, Grewal, R P, Gudnason, V, Gustafsson, S, Haessler, J, Harris, T B, Hassan, A, Havulinna, A S, Heckbert, S R, Holliday, E G, Howard, G, Hsu, F-C, Hyacinth, H I, Arfan Ikram, M, Ingelsson, E, Irvin, M R, Jian, X, Jiménez-Conde, J, Johnson, J A, Jukema, J W, Kanai, M, Keene, K L, Kissela, B M, Kleindorfer, D O, Kooperberg, C, Kubo, M, Lange, L A, Langefeld, C D, Langenberg, C, Launer, L J, Lee, J-M, Lemmens, R, Leys, D, Lewis, C M, Lin, W-Y, Lindgren, A G, Lorentzen, E, Magnusson, P K, Maguire, J, Manichaikul, A, McArdle, P F, Meschia, J F, Mitchell, B D, Mosley, T H, Nalls, M A, Ninomiya, T, O’Donnell, M J, Psaty, B M, Pulit, S L, Rannikmäe, K, Reiner, A P, Rexrode, K M, Rice, K, Rich, S S, Ridker, P M, Rost, N S, Rothwell, P M, Rotter, J I, Rundek, T, Sacco, R L, Sakaue, S, Sale, M M, Salomaa, V, Sapkota, B R, Schmidt, R, Schmidt, C O, Schminke, U, Sharma, P, Slowik, A, Sudlow, C L M, Tanislav, C, Tatlisumak, T, Taylor, K D, Thijs, V N S, Thorleifsson, G, Thorsteinsdottir, U, Tiedt, S, Trompet, S, Tzourio, C, van Duijn, C M, Walters, M, Wareham, N J, Wassertheil-Smoller, S, Wilson, J G, Wiggins, K L, Yang, Q, Yusuf, S, Amin, N, Aparicio, H S, Arnett, D K, Attia, J, Beiser, A S, Berr, C, Buring, J E, Bustamante, M, Caso, V, Cheng, Y-C, Hoan Choi, S, Chowhan, A, Cullell, N, Dartigues, J-F, Delavaran, H, Delgado, P, Dörr, M, Engström, G, Ford, I, Gurpreet, W S, Hamsten, A, Heitsch, L, Hozawa, A, Ibanez, L, Ilinca, A, Ingelsson, M, Iwasaki, M, Jackson, R D, Jood, K, Jousilahti, P, Kaffashian, S, Kalra, L, Kamouchi, M, Kitazono, T, Kjartansson, O, Kloss, M, Koudstaal, P J, Krupinski, J, Labovitz, D L, Laurie, C C, Levi, C R, Li, L, Lind, L, Lindgren, C M, Lioutas, V, Mei Liu, Y, Lopez, O L, Makoto, H, Martinez-Majander, N, Matsuda, K, Minegishi, N, Montaner, J, Morris, A P, Muiño, E, Müller-Nurasyid, M, Norrving, B, Ogishima, S, Parati, E A, Reddy Peddareddygari, L, Pedersen, N L, Pera, J, Perola, M, Pezzini, A, Pileggi, S, Rabionet, R, Riba-Llena, I, Ribasés, M, Romero, J R, Roquer, J, Rudd, A G, Sarin, A-P, Sarju, R, Sarnowski, C, Sasaki, M, Satizabal, C L, Satoh, M, Sattar, N, Sawada, N, Sibolt, G, Sigurdsson, Á, Smith, A, Sobue, K, Soriano-Tárraga, C, Stanne, T, Colin Stine, O, Stott, D J, Strauch, K, Takai, T, Tanaka, H, Tanno, K, Teumer, A, Tomppo, L, Torres-Aguila, N P, Touze, E, Tsugane, S, Uitterlinden, A G, Valdimarsson, E M, van der Lee, S J, Völzke, H, Wakai, K, Weir, D, Williams, S R, Wolfe, C D A, Wong, Q, Xu, H, Yamaji, T, Sanghera, D K, Melander, O, Jern, C, Strbian, D, Fernandez-Cadenas, I, Longstreth, W T, Rolfs, A, Hata, J, Woo, D, Rosand, J, Pare, G, Hopewell, J C, Saleheen, D, Stefansson, K, Worrall, B B, Kittner, S J, Seshadri, S, Fornage, M, Markus, H S, Howson, J M M, Kamatani, Y, Debette, S & Dichgans, M 2022, ' Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations ', Journal of Thrombosis and Haemostasis, vol. 20, no. 6, pp. 1331-1349 . https://doi.org/10.1111/jth.15698Test
Journal of Thrombosis and Haemostasis, 20(6), 1331-1349. Wiley-Blackwell

مصطلحات موضوعية: Hemostasis, genome-wide association study, genetic pleiotropy, Hematology, Polymorphism, Single Nucleotide, Hemostatics, blood coagulation, cardiovascular diseases, Phenotype, Cardiovascular Diseases, Tissue Plasminogen Activator, hemostasis, Humans, Genetic Predisposition to Disease, Factor XI, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b7442423f44fe602d89a89feee11d1Test
https://hdl.handle.net/20.500.11820/264ae571-0038-4372-9a30-c81b5c9f6905Test

المؤلفون: Dong Heon Lee, Shih-Jen Hwang, Thorsten M. Schlaeger, Arunoday Bhan, Ming-Huei Chen, Daniel Levy, Joshua Keefe, Andrew D. Johnson, Benjamin At Rodriguez, Chen Yao

المصدر: Circ Res

مصطلحات موضوعية: Blood Platelets, Male, Pluripotent Stem Cells, Risk, Protein biomarkers, Physiology, CD146 Antigen, Platelet Membrane Glycoproteins, Disease, Bioinformatics, Proteomics, Article, Thromboembolism, Mendelian randomization, Humans, Medicine, Platelet, Gene Silencing, Longitudinal Studies, RNA, Small Interfering, Mean platelet volume, Granulins, Megakaryocyte Progenitor Cells, Peroxidase, Platelet Count, Sequence Analysis, RNA, business.industry, Peas, Cell Differentiation, Genomics, Blood Proteins, Mendelian Randomization Analysis, Middle Aged, Phenotype, Cardiovascular Diseases, Female, Cardiology and Cardiovascular Medicine, business, Mean Platelet Volume, Megakaryocytes, Biomarkers, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefc4a1864daf24b01a90707f82b11bcTest
https://doi.org/10.1161/circresaha.119.316447Test

المؤلفون: Paul Charles Armstrong, Andrew D. Johnson, Jennifer E. Huffman, Johann Willeit, Brigitte Wierer, Manuel Mayr, Temo Barwari, Melissa V. Chan, Stefan Kiechl, Timothy D. Warner, Ming-Huei Chen, Peter Santer, Shih-Jen Hwang

المصدر: Circulation Research

مصطلحات موضوعية: Blood Platelets, Male, medicine.medical_specialty, Aging, Platelet aggregation, Platelet Aggregation, Platelet Function Tests, Physiology, aspirin, Arterial Occlusive Diseases, Risk Assessment, Platelet reactivity, Sex Factors, Internal medicine, medicine, Humans, Myocardial infarction, Prospective Studies, Aged, risk, Aged, 80 and over, Aspirin, business.industry, Age Factors, medicine.disease, Research Letters, cardiovascular diseases, myocardial infarction, Italy, Heart Disease Risk Factors, Cardiology, Female, atherosclerosis, Cardiology and Cardiovascular Medicine, business, Platelet Aggregation Inhibitors, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edcc8b234237c2a4ff375900fda03c2Test
https://pubmed.ncbi.nlm.nih.gov/32336198Test

المؤلفون: Yoav Ben-Shlomo, Ming-Huei Chen, Peter Creighton Elwood, Arunoday Bhan, Mete Civelek, FinnGen Study, David-Alexandre Trégouët, Veikko Salomaa, Benjamin Rodriguez, Teemu J. Niiranen, Thorsten M. Schlaeger, Andrew D. Johnson, Andrew D Beswick, Pierre-Emmanuel Morange

المساهمون: Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

المصدر: American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), In press, 107 (2), pp.211-221. ⟨10.1016/j.ajhg.2020.06.008⟩
American Journal of Human Genetics, In press, 107 (2), pp.211-221. ⟨10.1016/j.ajhg.2020.06.008⟩
Am J Hum Genet
Rodriguez, B A T, Bhan, A, Beswick, A, Elwood, P C, Niiranen, T J, Salomaa, V, Trégouët, D-A, Morange, P-E, Civelek, M, Ben-Shlomo, Y, Schlaeger, T, Chen, M-H & Johnson, A D 2020, ' A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling ', American Journal of Human Genetics . https://doi.org/10.1016/j.ajhg.2020.06.008Test

مصطلحات موضوعية: 0301 basic medicine, Male, Platelet Aggregation, Embolism, Genome-wide association study, 030204 cardiovascular system & hematology, Pharmacology, 0302 clinical medicine, Megakaryocyte, Cardiovascular Disease, Neoplasms, Medicine, Platelet, Receptor, Lung, Genetics (clinical), Thrombin, Middle Aged, thrombin, stroke, 3. Good health, Stroke, medicine.anatomical_structure, VINTAGE, Cardiovascular Diseases, Female, medicine.drug, Signal Transduction, Platelets, Blood Platelets, venous thromboembolism, eQTL, GWA, Article, 03 medical and health sciences, Downregulation and upregulation, Mendelian randomization, Genetics, Humans, Receptor, PAR-1, Platelet activation, thrombosis, Alleles, Heart Failure, business.industry, Platelet Activation, 030104 developmental biology, Receptors, Thrombin, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed6f4d72d2a9d16e1e20ed0efb7eff0Test
https://hal.archives-ouvertes.fr/hal-03141739Test

المؤلفون: Nauder Faraday, Lisa R. Yanek, Richard A. Gibbs, Narayanan Veeraraghavan, Rasika A. Mathias, John D. Eicher, Lewis C. Becker, Eric Boerwinkle, Jennifer A. Brody, Honghuang Lin, Donna M. Muzny, L. Adrienne Cupples, Ginger A. Metcalf, Andrew D. Johnson, Diane M. Becker, Achilleas N. Pitsillides, Ming-Huei Chen

المصدر: Thrombosis and Haemostasis. 117:1083-1092

مصطلحات موضوعية: Adult, Blood Platelets, Male, 0301 basic medicine, Epinephrine, Genotype, Platelet Aggregation, Population, Hyaluronoglucosaminidase, Disease, Gene mutation, GSTZ1, Biology, GPI-Linked Proteins, Cohort Studies, 03 medical and health sciences, Framingham Heart Study, Population Groups, Exome Sequencing, Humans, Missense mutation, Exome, education, Gene, Alleles, Exome sequencing, Genetics, education.field_of_study, Polymorphism, Genetic, Membrane Proteins, Hematology, Middle Aged, Phosphoproteins, Adenosine Diphosphate, Protein Transport, 030104 developmental biology, Massachusetts, Cardiovascular Diseases, Mutation, Female, Cell Adhesion Molecules

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a7304d7a29263b018de9266acd175cTest
https://doi.org/10.1160/th16-09-0677Test

المؤلفون: Ching-Yu Cheng, Alexander Teumer, Cristian Pattaro, Peter Vollenweider, Heribert Schunkert, Lenore J. Launer, Reinhold Schmidt, Josef Coresh, Joshua C. Bis, Christopher J. O'Donnell, Stephen T. Turner, W. H. Linda Kao, François Bastardot, Matthias Olden, Rainer Rettig, Conall M. O'Seaghdha, Germaine C. Verwoert, David S. Siscovick, Abbas Dehghan, Myriam Fornage, Ming-Huei Chen, Xueling Sim, Anna Köttgen, Muredach P. Reilly, Caroline S. Fox, Murielle Bochud, Gary F. Mitchell

المساهمون: Epidemiology, CKDGen Consortia, AortaGen CARDIoGRAM CHARGE Eye CHARGE IMT ICBP, NeuroCHARGE

المصدر: American Journal of Kidney Diseases, 61(6), 889-898. W.B. Saunders
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation, vol. 61, no. 6, pp. 889-898

مصطلحات موضوعية: Adult, Male, Oncology, Pathology, medicine.medical_specialty, Population, Renal function, Blood Pressure, Single-nucleotide polymorphism, Genome-wide association study, Carotid Intima-Media Thickness, Polymorphism, Single Nucleotide, Coronary artery disease, SDG 3 - Good Health and Well-being, Internal medicine, medicine, Humans, Renal Insufficiency, Chronic, education, Adaptor Proteins, Signal Transducing, Aged, education.field_of_study, business.industry, Intracellular Signaling Peptides and Proteins, Proteins, Middle Aged, medicine.disease, Blood pressure, Cardiovascular Diseases, Nephrology, Albuminuria, Female, medicine.symptom, business, Genome-Wide Association Study, Glomerular Filtration Rate, Kidney disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b5e84690406c5c66805d5f2d361019Test
https://doi.org/10.1053/j.ajkd.2012.12.024Test

المؤلفون: James L. Januzzi, Kai C. Wollert, Lars Lind, Erik Ingelsson, Thomas J. Wang, Cecilia M. Lindgren, Elizabeth L. McCabe, Jennifer E. Ho, Andrew P. Morris, Susan Cheng, Tibor Kempf, Anahita Ghorbani, Anubha Mahajan, Ming-Huei Chen, Martin G. Larson, Andrew D. Johnson, Ramachandran S. Vasan

المصدر: Clinical Chemistry. 58:1582-1591

مصطلحات موضوعية: Male, medicine.medical_specialty, Growth Differentiation Factor 15, Offspring, Quantitative Trait Loci, Clinical Biochemistry, Locus (genetics), Genome-wide association study, 030204 cardiovascular system & hematology, Quantitative trait locus, Biology, Polymorphism, Single Nucleotide, Article, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Diabetes mellitus, medicine, Humans, Genetic Predisposition to Disease, Aged, 030304 developmental biology, 0303 health sciences, Framingham Risk Score, Cholesterol, HDL, Biochemistry (medical), Middle Aged, medicine.disease, 3. Good health, Endocrinology, Cardiovascular Diseases, Multivariate Analysis, Female, GDF15, Genome-Wide Association Study, Cohort study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daec179300e15edf27ffd800174ac971Test
https://doi.org/10.1373/clinchem.2012.190322Test

المؤلفون: Nicole L. Glazer, Cheryl Ingram, John F. Keaney, Vanessa Xanthakis, Christopher J. O'Donnell, Danielle Enserro, David D. McManus, Lisa M. Sullivan, Bernhard M. Kaess, Ramachandran S. Vasan, Ming-Huei Chen

المصدر: The Journal of Clinical Endocrinology & Metabolism. 97:E1943-E1947

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, alpha-2-HS-Glycoprotein, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Context (language use), Fatty Acid-Binding Proteins, Biochemistry, Body Mass Index, Endocrinology, Insulin resistance, Framingham Heart Study, Risk Factors, Internal medicine, Diabetes mellitus, medicine, Humans, Sex Distribution, Adiposity, Metabolic Syndrome, Sex Characteristics, Retinol binding protein 4, biology, Biochemistry (medical), JCEM Online: Brief Reports, Middle Aged, medicine.disease, Retinol binding protein, C-Reactive Protein, Massachusetts, Cardiovascular Diseases, Multivariate Analysis, biology.protein, Female, Insulin Resistance, Metabolic syndrome, Retinol-Binding Proteins, Plasma, alpha-2-HS-glycoprotein, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff95830e0b2b0a6d9989fb643f14817Test
https://doi.org/10.1210/jc.2012-1458Test

المؤلفون: Joshua C. Bis, Jens Baumert, Bruce M. Psaty, Barbara McKnight, Saonli Basu, Albert Hofman, Kent D. Taylor, Ming-Huei Chen, Maryam Kavousi, Christopher J. O'Donnell, Susana Eyhermendy, Moniek P.M. de Maat, Nicholas L. Smith, David Couper, Andrew D. Johnson, David P. Strachan, Wolfgang Koenig, Gordon D.O. Lowe, Christian Gieger, Wendy L. McArdle, Jacqueline C.M. Witteman, Martin G. Larson, Yurii S. Aulchenko, James S. Pankow, Fernando Rivadeneira, Thomas Lumley, Aaron R. Folsom, Qiong Yang, Eric Boerwinkle, Cornelia M. van Duijn, Weihong Tang, Joseph M. Massaro, Annette Peters, Alicja R Rudnicka, André G. Uitterlinden, Kelly A. Volcik, Thomas Illig, Geoffrey H. Tofler, Abbas Dehghan, Melanie Kolz, Sekar Kathiresan

المساهمون: Epidemiology, Internal Medicine

المصدر: Dehghan, A, Yang, Q, Peters, A, Basu, S, Bis, J C, Rudnicka, A R, Kavousi, M, Chen, M-H, Baumert, J, Lowe, G D O, McKnight, B, Tang, W, de Maat, M, Larson, M G, Eyhermendy, S, McArdle, W L, Lumley, T, Pankow, J S, Hofman, A, Massaro, J M, Rivadeneira, F, Kolz, M, Taylor, K D, van Duijn, C M, Kathiresan, S, Illig, T, Aulchenko, Y S, Volcik, K A, Johnson, A D, Uitterlinden, A G, Tofler, G H, Gieger, C, Psaty, B M, Couper, D J, Boerwinkle, E, Koenig, W, O'Donnell, C J, Witteman, J C, Strachan, D P, Smith, N L, Folsom, A R 2009, ' Association of novel genetic Loci with circulating fibrinogen levels : a genome-wide association study in 6 population-based cohorts ', Circulation: Cardiovascular Genetics, vol. 2, no. 2, pp. 125-33 . https://doi.org/10.1161/CIRCGENETICS.108.825224Test
Circulation-cardiovascular genetics, 2(2), 125-133. Lippincott Williams & Wilkins

مصطلحات موضوعية: Adult, Male, Genome-wide association study, Population based, Biology, Fibrinogen, Polymorphism, Single Nucleotide, White People, Article, Cohort Studies, Young Adult, Fibrinogen levels, Polymorphism (computer science), Genetics, medicine, Humans, Gene, Genetics (clinical), Aged, Aged, 80 and over, Medicine(all), Middle Aged, Pedigree, Coagulation, Cardiovascular Diseases, Genetic Loci, Meta-analysis, Female, Cardiology and Cardiovascular Medicine, Genome-Wide Association Study, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6206afc7b50db90ede0dbebb4febbefTest
https://doi.org/10.1161/circgenetics.108.825224Test

المؤلفون: Man Li, Vilmundur Gudnason, Eric Boerwinkle, Christopher J. O'Donnell, Cornelia M. van Duijn, Thor Aspelund, Guo Li, Dan E. Arking, Paul M. Ridker, Talin Haritunians, Tamara B. Harris, W. H. Linda Kao, Abbas Dehghan, Alex Parker, Bruno H. Stricker, Thomas Lumley, David S. Siscovick, Daniel I. Chasman, Michael G. Shlipak, Bruce M. Psaty, Megan L. Grove, Albert Hofman, Lenore J. Launer, Ashish Upadhyay, Josef Coresh, Fernando Rivadeneira, Albert V. Smith, Gudny Eiriksdottir, Jacqueline C.M. Witteman, Martin G. Larson, Dena G. Hernandez, Anna Köttgen, Michel Chonchol, Nicole L. Glazer, André G. Uitterlinden, Ming-Huei Chen, Caroline S. Fox, Mike A. Nalls, Qiong Yang, Guillaume Paré, Shih-Jen Hwang

المساهمون: Epidemiology, Public Administration, Internal Medicine

المصدر: Circulation-cardiovascular genetics, 3(6), 523-530. Lippincott Williams & Wilkins

مصطلحات موضوعية: Male, medicine.medical_specialty, Gout, Coronary Disease, Genome-wide association study, Article, chemistry.chemical_compound, SDG 3 - Good Health and Well-being, Risk Factors, Internal medicine, Genetics, Genetic predisposition, Humans, Medicine, Genetics (clinical), biology, business.industry, Mendelian Randomization Analysis, medicine.disease, Uric Acid, Endocrinology, chemistry, Cardiovascular Diseases, Genetic Loci, Meta-analysis, Immunology, biology.protein, Uric acid, Female, SLC22A12, Cardiology and Cardiovascular Medicine, business, Genome-Wide Association Study, SLC2A9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd613c509ad3dde879a5e610f38aebcTest
https://doi.org/10.1161/circgenetics.109.934455Test