Short- and Long-Term Mortality Trends in STEMI-Cardiogenic Shock over Three Decades (1989-2018): The Ruti-STEMI-Shock Registry
| العنوان: | Short- and Long-Term Mortality Trends in STEMI-Cardiogenic Shock over Three Decades (1989-2018): The Ruti-STEMI-Shock Registry |
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| المؤلفون: | Garcia Garcia, Cosme, Oliveras, Teresa, El Ouaddi, Nabil, Rueda, Ferran, Serra Flores, Jordi, Labata, Carlos, Ferrer, Marc, Cediel, Germán, Montero, Santiago, Martínez, Maria Jose, Resta, Helena, De Diego, Oriol, Vila, Joan, Degano, Irene R., Elosua, Roberto, Lupón, Josep, Bayés-Genís, Antoni, Universitat Autònoma de Barcelona. Departament de Medicina |
| المصدر: | Journal of Clinical Medicine r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol instname Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Volume 9 Issue 8 Journal of Clinical Medicine, Vol 9, Iss 2398, p 2398 (2020) |
| بيانات النشر: | MDPI, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, lcsh:Medicine, 030204 cardiovascular system & hematology, Article, STEMI mortality, 03 medical and health sciences, 0302 clinical medicine, Reperfusion therapy, Internal medicine, medicine, 030212 general & internal medicine, Myocardial infarction, cardiovascular diseases, Proportional hazards model, business.industry, Cardiogenic shock, Mortality rate, lcsh:R, General Medicine, medicine.disease, surgical procedures, operative, ST-elevation myocardial infarction, STEMI complications, Shock (circulatory), Long term mortality, prognosis, medicine.symptom, Complication, business |
| الوصف: | Aims: Cardiogenic shock (CS) is an ominous complication of ST-elevation myocardial infarction (STEMI), despite the recent widespread use of reperfusion and invasive management. The Ruti-STEMI-Shock registry analysed the prevalence of and 30-day and 1-year mortality rates in ST-elevation myocardial infarction (STEMI) complicated by CS (STEMI-CS) over the last three decades. Methods and Results: From February 1989 to December 2018, 493 STEMI-CS patients were consecutively admitted in a well-defined geographical area of ~850,000 inhabitants. Patients were classified into six five-year periods based on their year of admission. STEMI-CS mortality trends were analysed at 30 days and 1 year across the six strata. Cox regression analyses were performed for comparisons. Mean age was 67.5 ± 11.7 years 69.4% were men. STEMI-CS prevalence did not decline from period 1 to 6 (7.1 vs. 6.2%, p = 0.218). Reperfusion therapy increased from 22.5% in 1989&ndash 1993 to 85.4% in 2014&ndash 2018. Thirty-day all-cause mortality declined from period 1 to 6 (65% vs. 50.5%, p < 0.001), with a 9% reduction after multivariable adjustment (HR: 0.91 95% CI: 0.84&ndash 0.99 p = 0.024). One-year all-cause mortality declined from period 1 to 6 (67.5% vs. 57.3%, p = 0.001), with an 8% reduction after multivariable adjustment (HR: 0.92 95% CI: 0.85&ndash p = 0.030). Short- and long-term mortality trends in patients aged &ge 75 years remained ~75%. Conclusions: Short- and long-term STEMI-CS-related mortality declined over the last 30 years, to ~50% of all patients. We have failed to achieve any mortality benefit in STEMI-CS patients over 75 years of age. |
| وصف الملف: | application/pdf |
| تدمد: | 2077-0383 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbb684e2fb1a79536734dabd6215b3eTest https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3675Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....dbbb684e2fb1a79536734dabd6215b3e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20770383 |
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