التفاصيل البيبلوغرافية
| العنوان: |
Accuracy of Cardiac Magnetic Resonance Imaging in Diagnosing Pediatric Cardiac Masses: A Multicenter Study |
| المؤلفون: |
Beroukhim, Rebecca S, Ghelani, Sunil, Ashwath, Ravi, Balasubramanian, Sowmya, Biko, David M, Buddhe, Sujatha, Campbell, M Jay, Cross, Russell, Festa, Pierluigi, Griffin, Lindsay, Grotenhuis, Heynric, Hasbani, Keren, Hashemi, Sassan, Hegde, Sanjeet, Hussain, Tarique, Jain, Supriya, Kiaffas, Maria, Kutty, Shelby, Lam, Christopher Z, Liberato, Gabriela, Merlocco, Anthony, Misra, Nilanjana, Mowers, Katie L, Muniz, Juan Carlos, Nutting, Arni, Parra, David A, Patel, Jyoti K, Perez-Atayde, Antonio R, Prasad, Deepa, Rosental, Carlos F, Shah, Amee, Samyn, Margaret M, Sleeper, Lynn A, Slesnick, Timothy, Valsangiacomo, Emanuela, Geva, Tal |
| المساهمون: |
Cardiologie patientenzorg, Child Health, Circulatory Health |
| سنة النشر: |
2022 |
| مصطلحات موضوعية: |
cardiac magnetic resonance, cardiac mass, cardiac tumor, pediatric, Radiology Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine |
| الوصف: |
BACKGROUND: After diagnosis of a cardiac mass, clinicians must weigh the benefits and risks of ascertaining a tissue diagnosis. Limited data are available on the accuracy of previously developed noninvasive pediatric cardiac magnetic resonance (CMR)-based diagnostic criteria. OBJECTIVES: The goals of this study were to: 1) evaluate the CMR characteristics of pediatric cardiac masses from a large international cohort; 2) test the accuracy of previously developed CMR-based diagnostic criteria; and 3) expand diagnostic criteria using new information. METHODS: CMR studies (children 0-18 years of age) with confirmatory histological and/or genetic diagnosis were analyzed by 2 reviewers, without knowledge of prior diagnosis. Diagnostic accuracy was graded as: 1) single correct diagnosis; 2) correct diagnosis among a differential; or 3) incorrect diagnosis. RESULTS: Of 213 cases, 174 (82%) had diagnoses that were represented in the previously published diagnostic criteria. In 70% of 174 cases, both reviewers achieved a single correct diagnosis (94% of fibromas, 71% of rhabdomyomas, and 50% of myxomas). When ≤2 differential diagnoses were included, both reviewers reached a correct diagnosis in 86% of cases. Of 29 malignant tumors, both reviewers indicated malignancy as a single diagnosis in 52% of cases. Including ≤2 differential diagnoses, both reviewers indicated malignancy in 83% of cases. Of 6 CMR sequences examined, acquisition of first-pass perfusion and late gadolinium enhancement were independently associated with a higher likelihood of a single correct diagnosis. CONCLUSIONS: CMR of cardiac masses in children leads to an accurate diagnosis in most cases. A comprehensive imaging protocol is associated with higher diagnostic accuracy. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| تدمد: |
1936-878X |
| العلاقة: |
https://dspace.library.uu.nl/handle/1874/445414Test |
| الإتاحة: |
https://dspace.library.uu.nl/handle/1874/445414Test |
| حقوق: |
info:eu-repo/semantics/ClosedAccess |
| رقم الانضمام: |
edsbas.E2686714 |
| قاعدة البيانات: |
BASE |
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