المؤلفون: José N. Nobrega, Tarek K. Rajji, Bruce G. Pollock, Roger Raymond

المصدر: Journal of Pharmacological and Toxicological Methods. 112:107118

مصطلحات موضوعية: Agonist, Carbachol, medicine.drug_class, Pharmacology, Toxicology, Fluorescence, Calcium in biology, Cricetulus, Cricetinae, medicine, Animals, Humans, Fluorometry, Pharmacokinetics, Receptors, Cholinergic, Cognitive decline, Acetylcholine receptor, Chemistry, Receptor, Muscarinic M1, Antagonist, Muscarinic acetylcholine receptor M1, Radioactivity, Pharmaceutical Preparations, Cholinergic, Calcium, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162de83b3e6b13d4403ffbc148be4f20Test
https://doi.org/10.1016/j.vascn.2021.107118Test

المؤلفون: Jelena Momirov, Alena Randáková, John Boulos, Jan Jakubík, John M. Boulos

المصدر: Chemical Biology & Drug Design. 91:93-104

مصطلحات موضوعية: 0301 basic medicine, Carbachol, Pyridines, Pilot Projects, CHO Cells, Muscarinic Antagonists, Pharmacology, Ligands, Biochemistry, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Allosteric Regulation, Cricetinae, Drug Discovery, Muscarinic acetylcholine receptor M5, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, medicine, Animals, Humans, Protein Isoforms, Binding Sites, Chemistry, Organic Chemistry, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, N-Methylscopolamine, Receptors, Muscarinic, 030104 developmental biology, Drug Design, Acetylcholinesterase, Molecular Medicine, Pharmacophore, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b579d475c0acbbac04c6b9a5286c50Test
https://doi.org/10.1111/cbdd.13059Test

المؤلفون: Yong-Yao Cui, Wei Zhou, Kai Yang, Liang Zhu, Hong-Zhuan Chen, Lina Hou, Yun Song, Zu-Peng Xu

المصدر: Inflammation Research. 63:463-473

مصطلحات موضوعية: Receptor, Muscarinic M3, Pharmacology, Carbachol, Chemistry, Interleukin-8, Immunology, NF-kappa B, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, Cholinergic Agonists, Cell biology, chemistry.chemical_compound, Calphostin C, Cell Line, Tumor, medicine, Muscarinic acetylcholine receptor M4, Humans, Mitogen-Activated Protein Kinases, Signal transduction, Protein Kinase C, Protein kinase C, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f6d272afdf23b0d30d50ddcb0ecbd3Test
https://doi.org/10.1007/s00011-014-0718-4Test

المؤلفون: Niva Natan, Lili Wu, Victoria Nahum, Abraham Fisher, Eitan Gershonov, Nira Bar-Ner, Hanoch Elkon, Rodrigo Medeiros, Frank M. LaFerla, Ilya Bezprozvanny, Daniel A. Ryskamp, Rachel Brandeis

المصدر: Fisher, Abraham; Bezprozvanny, Ilya; Wu, Lili; Ryskamp, Daniel A; Bar-Ner, Nira; Natan, Niva; et al.(2016). AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease.. Neuro-degenerative diseases, 16(1-2), 95-110. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/0rm238hcTest

مصطلحات موضوعية: 0301 basic medicine, Male, drug effects, physiology [Avoidance Learning], Drug Evaluation, Preclinical, Morris water navigation task, chemistry, pharmacology [Thiazolidines], Pharmacology, Hippocampus, PC12 Cells, Rats, Sprague-Dawley, 0302 clinical medicine, Muscarinic acetylcholine receptor, Medicine and Health Sciences, Receptor, Nootropic Agents, Cerebral Cortex, Chemistry, Muscarinic acetylcholine receptor M1, agonists, metabolism [Receptors, sigma], drug therapy, metabolism, pathology [Alzheimer Disease], pathology [Cerebral Cortex], 3. Good health, Neurology, Thiazolidines, Female, Alzheimer's disease, pharmacology [Nootropic Agents], medicine.drug, Agonist, medicine.medical_specialty, Carbachol, medicine.drug_class, pharmacology [Spiro Compounds], Allosteric regulation, Mice, Transgenic, Article, 03 medical and health sciences, Allosteric Regulation, Alzheimer Disease, Internal medicine, physiology [Maze Learning], metabolism [Receptor, Muscarinic M1], medicine, Avoidance Learning, Animals, Humans, Receptors, sigma, Spiro Compounds, pathology [Synapses], Rats, Wistar, Maze Learning, pathology [Hippocampus], Receptor, Muscarinic M1, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Endocrinology, Synapses, Neurology (clinical), 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c808f1fecaeec6a83b471e4875eadfeTest
https://europepmc.org/articles/PMC4803577Test/

المؤلفون: Giulio Vistoli, Laura Raimondi, Rosanna Matucci, Annunziatina Laurino

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, 3-iodothyrothyronamine, Urinary Bladder, Muscarinic receptors, Muscarinic Antagonists, Pharmacology, 03 medical and health sciences, Internal medicine, Catalytic Domain, Cricetinae, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M5, medicine, Muscarinic acetylcholine receptor M4, Thyronines, Animals, Humans, Phosphorylation, Receptor, Thyroid, Mitogen-Activated Protein Kinase 1, Receptor, Muscarinic M3, Mitogen-Activated Protein Kinase 3, Chemistry, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, Acetylcholine, Rats, Molecular Docking Simulation, 3-iodothyroacetic acid, 030104 developmental biology, Endocrinology, Carbachol, medicine.drug, Muscle Contraction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01eb65ef66fdd7244b6881399adb955Test
http://hdl.handle.net/2158/1079396Test

المؤلفون: Vincenzo Mirone, Raffaella Sorrentino, Erminia Donnarumma, Annapina Russo, Valentina Pagliara, Giuseppe Cirino, Teresa Tramontano, Giulia Russo, Ferdinando Fusco, Emma Mitidieri, Roberta d'Emmanuele di Villa Bianca

المساهمون: D'EMMANUELE DI VILLA BIANCA, Roberta, Mitidieri, Emma, Fusco, Ferdinando, Russo, Annapina, Pagliara, Valentina, Tramontano, Teresa, Donnarumma, Erminia, Mirone, Vincenzo, Cirino, Giuseppe, Russo, Giulia, Sorrentino, Raffaella

المصدر: Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Carbachol, Cystathionine beta-Synthase, Stimulation, Muscarinic Antagonists, urologic and male genital diseases, Article, CBS, muscarinic receptor, 03 medical and health sciences, Internal medicine, Muscarinic acetylcholine receptor, urothelium, hydrogen sulphide, muscarinic receptors, CBS, phosphorilation, Cyclic GMP-Dependent Protein Kinases, Serine, medicine, Humans, Hydrogen Sulfide, Phosphorylation, Urothelium, Receptor, Cyclic GMP, Multidisciplinary, Chemistry, Muscarinic acetylcholine receptor M3, urothelium, Muscarinic acetylcholine receptor M1, equipment and supplies, Receptors, Muscarinic, female genital diseases and pregnancy complications, Cell biology, phosphorilation, 030104 developmental biology, Endocrinology, Bladder Disorder, hydrogen sulphide, Muscle Contraction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbaafbce2074fa7b46b91e4f601c4c4Test
http://hdl.handle.net/11588/646778Test

المؤلفون: Andreas Rinne, Peter Kolb, Martyn P. Mahaut-Smith, Juan Carlos Mobarec, Moritz Bünemann

المصدر: Science signaling. 8(401)

مصطلحات موضوعية: Agonist, G protein, medicine.drug_class, Chemistry, Muscarinic acetylcholine receptor M3, Depolarization, Cell Biology, Muscarinic acetylcholine receptor M1, Muscarinic Agonists, Biochemistry, Receptors, Muscarinic, Acetylcholine, Membrane Potentials, HEK293 Cells, Mutation, medicine, Biophysics, Humans, Carbachol, Signal transduction, Receptor, Molecular Biology, G protein-coupled receptor, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb1be14e3b290b46446813b73857f7fTest
https://pubmed.ncbi.nlm.nih.gov/26535008Test

المؤلفون: Gregory P. Hussmann, Yingxian Xiao, Barry B. Wolfe, Robert P. Yasuda, Kenneth J. Kellar

المصدر: Journal of Biological Chemistry. 286:39726-39737

مصطلحات موضوعية: Nicotine, Carbachol, Receptors, Nicotinic, Pharmacology, Models, Biological, Biochemistry, Neurobiology, mental disorders, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, medicine, Humans, Nicotinic Agonists, RNA, Messenger, Receptor, Molecular Biology, Chemistry, musculoskeletal, neural, and ocular physiology, Muscarinic acetylcholine receptor M2, Cell Biology, Muscarinic acetylcholine receptor M1, Receptors, Muscarinic, HEK293 Cells, Nicotinic agonist, Gene Expression Regulation, nervous system, Competitive antagonist, sense organs, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1561b21fb64dc5c450b6e6405e1bba9Test
https://doi.org/10.1074/jbc.m111.289546Test

المؤلفون: Hiroshi Fushiki, Hisashi Ohta, Kazumi Koga, Yoko Ueno, Yoshio Ogino, Nozomi Ami

المصدر: Journal of Pharmacological Sciences, Vol 116, Iss 1, Pp 81-88 (2011)

مصطلحات موضوعية: medicine.medical_specialty, Carbachol, Lung Neoplasms, Cell Survival, Antineoplastic Agents, Mice, SCID, Muscarinic Antagonists, Muscarinic Agonists, Muscarinic agonist, Mice, Piperidines, Internal medicine, Cell Line, Tumor, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, medicine, Animals, Humans, Calcium Signaling, Cell Proliferation, Pharmacology, Receptor, Muscarinic M3, Mice, Inbred ICR, Dose-Response Relationship, Drug, Chemistry, lcsh:RM1-950, Muscarinic acetylcholine receptor M3, Muscarinic antagonist, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, Dipeptides, Small Cell Lung Carcinoma, Xenograft Model Antitumor Assays, Tumor Burden, respiratory tract diseases, Endocrinology, lcsh:Therapeutics. Pharmacology, Cancer research, Molecular Medicine, Female, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c711e2e80a43d77c17be6c11ac6c2a0Test
http://www.sciencedirect.com/science/article/pii/S1347861319307248Test

المؤلفون: Banu Aydın, Beki Kan, Hülya Cabadak

المصدر: Journal of Receptors and Signal Transduction. 31:26-32

مصطلحات موضوعية: Atropine, Time Factors, Carbachol, Blotting, Western, CHO Cells, Muscarinic Antagonists, Pharmacology, Biology, Biochemistry, Cricetulus, Cricetinae, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Muscarinic acetylcholine receptor M5, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, medicine, Animals, Humans, RNA, Messenger, Molecular Biology, Receptor, Muscarinic M3, Receptor, Muscarinic M2, Receptor, Muscarinic M4, Gene Expression Regulation, Leukemic, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Cell Biology, Muscarinic acetylcholine receptor M1, Receptors, Muscarinic, Molecular biology, K562 Cells, Acetylcholine, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b63df4355a2850eba289bba9aae9935Test
https://doi.org/10.3109/10799893.2010.506484Test