التفاصيل البيبلوغرافية
| العنوان: |
Epidemiologic changes in bloodstream infections in Andalucía (Spain) during the last decade. |
| المؤلفون: |
Martínez Pérez-Crespo, P.M.1 (AUTHOR), López-Cortés, L.E.1 (AUTHOR) luiselopezcortes@gmail.com, Retamar-Gentil, P.1 (AUTHOR), García, J.F. Lanz1 (AUTHOR), Vinuesa García, D.2 (AUTHOR), León, E.3 (AUTHOR), Calvo, J.M. Sánchez4 (AUTHOR), Galán-Sánchez, F.5 (AUTHOR), Natera Kindelan, C.6 (AUTHOR), del Arco Jiménez, A.7 (AUTHOR), Sánchez-Porto, A.8 (AUTHOR), Herrero Rodríguez, C.9 (AUTHOR), Becerril Carral, B.10 (AUTHOR), Molina, I.M. Reche11 (AUTHOR), Iglesias, J.M. Reguera12 (AUTHOR), Pérez Camacho, I.13 (AUTHOR), Guzman García, M.14 (AUTHOR), López-Hernández, I.1 (AUTHOR), Rodríguez-Baño, J.1 (AUTHOR) |
| المصدر: |
Clinical Microbiology & Infection. Feb2021, Vol. 27 Issue 2, p283.e9-283.e16. 1p. |
| مصطلحات موضوعية: |
*ODDS ratio, *MULTIVARIATE analysis, *LOGISTIC regression analysis, *URINARY catheters, *INFECTION, *CONFIDENCE intervals, *CANDIDEMIA |
| مصطلحات جغرافية: |
ANDALUSIA (Spain), SPAIN |
| مستخلص: |
During the last decade, some changes in the epidemiology of invasive infections have been reported; however, specific studies with patient-level data are scarce. The aim of this study was to describe and evaluate the epidemiologic changes in bloodstream infections (BSI) during the last decade in Andalucía, Spain. Data from two prospective cohorts of BSI in adults with the same methodology performed 10 years apart in 11 hospitals (eight tertiary and three community) in Andalucía, Spain, were compared; the 2006–7 cohort study was performed between October 2006 and March 2007, and the 2016–17 cohort study was performed between October 2016 and March 2017. Population-based incidence rates were calculated and extrapolated for 1 year. Relative risk ratios were calculated between the 2 periods. Multivariate analyses were performed by logistic regression. Overall, 1262 episodes of BSI were included, 563 (44.6%) in 2006–7 and 699 (55.3%) in 2016–17. Multivariate models selected the following changes in patients' features in 2016–17, after controlling for type of acquisition: higher age (odds ratio (OR) = 1.02; 95% confidence interval [CI] 1.01–1.03), lower urinary catheter (OR = 0.37; 95% CI, 0.26–0.48) and lower Pitt score (OR = 0.76; 95% CI, 0.71–0.82). Adjusted estimations considering patients' features and exposure to procedures showed a reduction in coagulase-negative staphylococci (OR = 0.47; 95% CI, 0.32–0.69), and an increase in Proteus spp. (OR = 3.12; 95% CI, 1.18–8.23) and Candida spp. (OR = 3.01; 95% CI, 1.03–8.86). We found relevant epidemiologic changes in BSI in our area, including rates, frequency of acquisition types, changes in patient's profiles and aetiologic agents. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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