دورية أكاديمية
“ Candida Albicans Interactions With The Host: Crossing The Intestinal Epithelial Barrier”
| العنوان: | “ Candida Albicans Interactions With The Host: Crossing The Intestinal Epithelial Barrier” |
|---|---|
| المؤلفون: | Basmaciyan, Louise, Bon, Fabienne, Paradis, Tracy, Lapaquette, Pierre, Dalle, Frédéric |
| المساهمون: | Laboratoire de parasitologie mycologie (CHU de Dijon), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Procédés Alimentaires et Microbiologiques Dijon (PAM), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université Bourgogne Franche-Comté COMUE (UBFC), Vin Aliment Microbiologie et Stress (VAlMiS), Procédés Alimentaires et Microbiologiques (PAM), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Procédés Alimentaires et Microbiologiques Dijon (PAM), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université Bourgogne Franche-Comté COMUE (UBFC)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université Bourgogne Franche-Comté COMUE (UBFC), AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Université Bourgogne Franche-Comté COMUE (UBFC) |
| المصدر: | EISSN: 2168-8370 ; Tissue Barriers ; https://u-bourgogne.hal.science/hal-02172078Test ; Tissue Barriers , 2019, 7 (2), pp.1612661. ⟨10.1080/21688370.2019.1612661⟩ ; https://www.tandfonline.com/doi/full/10.1080/21688370.2019.1612661Test |
| بيانات النشر: | HAL CCSD Taylord & Francis |
| سنة النشر: | 2019 |
| المجموعة: | Université de Bourgogne (UB): HAL |
| مصطلحات موضوعية: | Candida albicans, adherence, damage, enterocyte, infection models, interaction, intestinal barrier, invasion, [SDV.IDA]Life Sciences [q-bio]/Food engineering |
| الوصف: | International audience ; Formerly a commensal organism of the mucosal surfaces of most healthy individuals, Candida albicans is an opportunistic pathogen that causes infections ranging from superficial to the more life-threatening disseminated infections, especially in the ever-growing population of vulnerable patients in the hospital setting. In these situations, the fungus takes advantage of its host following a disturbance in the host defense system and/or the mucosal microbiota. Overwhelming evidence suggests that the gastrointestinal tract is the main source of disseminated C. albicans infections. Major risk factors for disseminated candidiasis include damage to the mucosal intestinal barrier, immune dysfunction, and dysbiosis of the resident microbiota. A better understanding of C. albicans' interaction with the intestinal epithelial barrier will be useful for designing future therapies to avoid systemic candidiasis. In this review, we provide an overview of the current knowledge regarding the mechanisms of pathogenicity that allow the fungus to reach and translocate the gut barrier. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/31189436; hal-02172078; https://u-bourgogne.hal.science/hal-02172078Test; PUBMED: 31189436; PUBMEDCENTRAL: PMC6619947 |
| DOI: | 10.1080/21688370.2019.1612661 |
| الإتاحة: | https://doi.org/10.1080/21688370.2019.1612661Test https://u-bourgogne.hal.science/hal-02172078Test |
| رقم الانضمام: | edsbas.E3A4D251 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1080/21688370.2019.1612661 |
|---|