نتائج البحث - "Roger J. Davis"

1

Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease

المصدر: Cancers
Dipòsit Digital de la UB
Universidad de Barcelona
Cancers, Vol 14, Iss 78, p 78 (2022)
Cancers; Volume 14; Issue 1; Pages: 78
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)

مصطلحات موضوعية: Cancer Research, c-Jun N-terminal kinases (JNK), Carcinogenesis, Malalties del fetge, cholangiocarcinoma (CCA), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, endoplasmic reticulum (ER) stress, Stressthioacetamide (TAA), Article, Oncology, fibropolycystic liver disease, thioacetamide (TAA), CM272, Cholangiocarcinoma (CCA), Endoplasmic reticulum (ER), Carcinogènesi, RC254-282, Liver diseases, Fibropolycystic liver disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6483fc845531aaf67f238b004196fdc9Test
https://pubmed.ncbi.nlm.nih.gov/35008241Test

2

c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease

المؤلفون: Julie A. Jonassen, Gregory J. Pazour, Roger J. Davis, Kenley Preval, Abigail O. Smith

المصدر: PLoS Genetics
PLoS Genetics, Vol 17, Iss 12, p e1009711 (2021)

مصطلحات موضوعية: Cancer Research, Cell signaling, Physiology, medicine.medical_treatment, QH426-470, Signal transduction, urologic and male genital diseases, Kidney, Biochemistry, Epithelium, Medical Conditions, Animal Cells, Polycystic kidney disease, Medicine and Health Sciences, Post-Translational Modification, Phosphorylation, Genetics (clinical), Cystic kidney, c-jun, Signaling cascades, Animal Models, Polycystic Kidney, Autosomal Dominant, c-Jun N-terminal kinase signaling cascade, Experimental Organism Systems, Physiological Parameters, Genetic Diseases, Anatomy, Cellular Types, Research Article, Cell biology, TRPP Cation Channels, MAP Kinase Signaling System, Autosomal dominant polycystic kidney disease, Mouse Models, Research and Analysis Methods, End stage renal disease, Cystic kidney disease, Model Organisms, Polycystic Kidney Disease, Weight Loss, medicine, Genetics, Humans, Mitogen-Activated Protein Kinase 9, Mitogen-Activated Protein Kinase 8, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Dialysis, Cell Proliferation, Clinical Genetics, PKD1, business.industry, urogenital system, Body Weight, Autosomal Dominant Diseases, JNK Mitogen-Activated Protein Kinases, Biology and Life Sciences, Proteins, Kidneys, Epithelial Cells, Renal System, medicine.disease, Fibrosis, Biological Tissue, Mutation, Cancer research, Animal Studies, business, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b84f3446b6baa3eda5738e929eeae6Test
http://europepmc.org/articles/PMC8746764Test

3

JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma

المؤلفون: Tamera Barrett, Julie Cavanagh-Kyros, Francisco Javier Cubero, Fátima Sánchez-Cabo, Davide Seruggia, Roger J. Davis, Laura Esteban-Lafuente, Chaobo Chen, Elisa Manieri, Maria J. Monte, María Elena Rodríguez, Guadalupe Sabio, Luis Leiva-Vega, Cintia Folgueira, Manuel Gómez, Alejandro Rosell, Jose J.G. Marin, Alfonso Mora

المساهمون: European Regional Development Fund (ERDF/FEDER), European Commission, European Research Council, Fundación BBVA, Ministerio de Ciencia e Innovación (España), Comunidad de Madrid, Fundación Científica AECC, Instituto de Salud Carlos III - ISCIII, Fundación ProCNIC, National Institutes of Health (United States), Ministerio de Economía y Competitividad (España), La Caixa, Asociación Española Contra el Cáncer, European Cooperation in Science and Technology, AMMF - The Cholangiocarcinoma Charity, Universidad Complutense de Madrid, National Institutes of Health (US), Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades (España), Fundación Severo Ochoa, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Unión Europea. Comisión Europea, Comunidad de Madrid (España), National Institutes of Health (Estados Unidos)

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Male, Medical Sciences, medicine.drug_class, Cholangiocyte proliferation, Peroxisome proliferator-activated receptor, Bile Acids and Salts, Cholangiocarcinoma, 03 medical and health sciences, Mice, 0302 clinical medicine, Cholestasis, medicine, bile acid, Animals, Homeostasis, Humans, Mitogen-Activated Protein Kinase 9, Mitogen-Activated Protein Kinase 8, PPAR alpha, Transcription factor, PPARa, 030304 developmental biology, chemistry.chemical_classification, Mice, Knockout, 0303 health sciences, Multidisciplinary, Bile acid, Chemistry, Kinase, Biological Sciences, medicine.disease, Mice, Inbred C57BL, 030220 oncology & carcinogenesis, Cancer research, PPARa Bile acid, JNK, Steatosis, Signal transduction