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المؤلفون: Ignacio Puche-Sanz, Pedro J. Real, Pablo Lupiañez, Sonia Perales, Iris Simon, Clara Alaminos, José A. Lorente, Alba Rodríguez-Martínez, Laura Casado-Medina, Juan J. Díaz-Mochón, María José Serrano, María del Carmen Garrido-Navas
المساهمون: [Simon,I, Perales,S, Casado-Medina,L, Lupiañez,P, Real,PJ] GENyO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Gene Regulation, Stem Cells & Development Lab, PTS Granada, Granada, Spain. [Simon,I, Real,PJ] Faculty of Science, Department of Biochemistry and Molecular Biology I, University of Granada, Granada, Spain. [Rodríguez-Martínez,A, Garrido-Navas,MDC, Lorente,JA, Serrano,MJ] GENyO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Liquid Biopsy and Cancer Interception Group, PTS Granada, Granada, Spain. [Rodríguez-Martínez,A, Lorente,JA] Faculty of Medicine, Legal Medicine and Toxicology Department, University of Granada, Laboratory of Genetic Identification, Spain. [Garrido-Navas,MDC] Universidad Internacional de la Rioja, Logroño, Spain. [Puche-Sanz,I] Department of Urology, Bio-Health Research Institute (Instituto de Investigación Biosanitaria ibs.GRANADA), Hospital Universitario Virgen de las Nieves, University of Granada, Granada, Spain. [Diaz-Mochon, JJ] GENyO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Nanochembio Lab, PTS Granada, Granada, Spain. [Diaz-Mochon,JJ] Department of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, Campus de Cartuja, University of Granada, Granada, Spain. [Alaminos,C] Department of Urology, University Hospital of Jaen, Jaen, Spain. [Serrano,MJ] Comprehensive Oncology Division, Clinical University Hospital, Virgen de las Nieves-IBS, Granada, Spain. [Serrano,MJ] Department of Pathological Anatomy, Faculty of Medicine, University of Granada, Granada, Spain. [Real, PJ] Bio-Health Research Institute (Instituto de Investigación Biosanitaria ibs.GRANADA), Personalized Oncology Group, Granada, Spain, This study was supported by the Institute of Health Carlos III, Spain (PI17/00989) to M.J.S. and cofunded by the European Regional Development Fund 'A way to build Europe' and the Ramon y Cajal (RYC-2015-18382) to P.J.R., funded by the Ministry of Economy and Competitiveness. A.R.-M. was supported by the predoctoral-University Teacher Training Program from the Ministry of Education, Culture and Sport (FPU14/05461), I.S. was supported by the Young Researcher program from University of Granada (Joven Personal Investigador-Fondo Social Europeo, Universidad de Granada (2018-19)) and a donation from Rolucan Association (Rota Lucha contra el Cancer).
المصدر: Cancers
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Cancers, Vol 13, Iss 1483, p 1483 (2021)
Volume 13
Issue 6مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings], castration resistant prostate cancer, Cell, Andrógenos, urologic and male genital diseases, Diseases::Male Urogenital Diseases::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms::Prostatic Neoplasms, Castration-Resistant [Medical Subject Headings], Androgen deprivation therapy, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Castration Resistance, Anatomy::Cells::Cells, Cultured::Cell Line [Medical Subject Headings], androgen receptor, abiraterone, transcriptional regulation, Abiraterone, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cytophotometry::Flow Cytometry [Medical Subject Headings], medicine.diagnostic_test, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Protein Isoforms [Medical Subject Headings], enzalutamide, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Androgen receptor, medicine.anatomical_structure, Elementos reguladores de la transcripción, Oncology, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormone Antagonists::Androgen Antagonists [Medical Subject Headings], 030220 oncology & carcinogenesis, Castration resistant prostate cancer, cross-resistance, Check Tags::Male [Medical Subject Headings], lcsh:RC254-282, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::RNA Processing, Post-Transcriptional::RNA Splicing::Alternative Splicing [Medical Subject Headings], Article, Flow cytometry, 03 medical and health sciences, Transcriptional regulation, Psychiatry and Psychology::Behavior and Behavior Mechanisms::Motivation::Goals [Medical Subject Headings], Acetato de abiraterona, medicine, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Androgens [Medical Subject Headings], Enzalutamide, Cross-resistance, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation [Medical Subject Headings], Cell growth, business.industry, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Urogenital Surgical Procedures::Castration [Medical Subject Headings], Neoplasias de la próstata resistentes a la castración, medicine.disease, 030104 developmental biology, chemistry, Novel hormonal agents, Cancer research, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Receptors, Cytoplasmic and Nuclear::Receptors, Steroid::Receptors, Androgen [Medical Subject Headings], business, AR-V7, AR-V9
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f963c522f34e705bb01ae3faeed08e75Test
http://europepmc.org/articles/PMC8004828Test -
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المؤلفون: Raimundo G. del Moral, Verónica Ramos-Mejía, Juan A. Marchal, Maria Luisa Lozano, José Rivera, Gonzalo Martínez-Navajas, Lourdes Lopez-Onieva, Pedro J. Real, José María Bastida, Rosa María Ríos-Pelegrina, Iris Simon, Rosa Montes, Carmen Griñán-Lisón, Sonia Perales, Mar Lamolda
المصدر: Stem Cell Research, Vol 41, Iss, Pp-(2019)
Digibug. Repositorio Institucional de la Universidad de Granada
instnameمصطلحات موضوعية: 0301 basic medicine, Platelet disorder, Induced Pluripotent Stem Cells, Biology, Peripheral blood mononuclear cell, 03 medical and health sciences, chemistry.chemical_compound, Blood Coagulation Disorders, Inherited, 0302 clinical medicine, In vivo, Humans, Induced pluripotent stem cell, lcsh:QH301-705.5, Cells, Cultured, Cell Differentiation, Cell Biology, General Medicine, Middle Aged, Cellular Reprogramming, In vitro, Leukemia, Myeloid, Acute, 030104 developmental biology, lcsh:Biology (General), RUNX1, chemistry, Core Binding Factor Alpha 2 Subunit, Mutation, Leukocytes, Mononuclear, Cancer research, Alkaline phosphatase, Female, Blood Platelet Disorders, Reprogramming, 030217 neurology & neurosurgery, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654c76578aefe9da3c9b8291df5dc1b2Test
https://doi.org/10.1016Test/j .scr.2019.101603 -
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المؤلفون: María L. Toribio, Clara Bueno, Oscar Navarro-Montero, Tamara Romero, Cristina Prieto, Anna Bigas, Pablo Menendez, Pedro J. Real, María J. García-León, Verónica Ramos-Mejía, Verónica Ayllón
المصدر: Leukemia. 29:1741-1753
مصطلحات موضوعية: Cancer Research, Cellular differentiation, Notch signaling pathway, Mice, SCID, Embryoid body, Biology, Real-Time Polymerase Chain Reaction, Immunoenzyme Techniques, Transcriptome, Mice, Mice, Inbred NOD, Animals, Humans, Endothelium, RNA, Messenger, Progenitor cell, Cells, Cultured, Embryoid Bodies, Embryonic Stem Cells, Cell Proliferation, Hemogenic endothelium, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Cell Differentiation, Hematology, Flow Cytometry, Hematopoietic Stem Cells, Hematopoiesis, Cell biology, Haematopoiesis, Oncology, Immunology, cardiovascular system, Female, Stem cell, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e136102e30e3cae921da5d893562ba7eTest
https://doi.org/10.1038/leu.2015.74Test -
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المؤلفون: Rosa Montes, Tamara Romero, Verónica Ayllón, Maria Luisa Lozano, Vicente Vicente, Pedro J. Real, Lourdes Lopez-Onieva, José Rivera, Mar Lamolda, Verónica Ramos-Mejía
المصدر: Stem Cell Research, Vol 17, Iss 2, p 462 (2016)
مصطلحات موضوعية: Medicine(all), General Medicine, Cell Biology, Biology, medicine.disease, Bernard–Soulier syndrome, lcsh:Biology (General), Mutation (genetic algorithm), medicine, Cancer research, Stem cell, Induced pluripotent stem cell, lcsh:QH301-705.5, Gene, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9158046269fe8b8ec6ed07fcb56ccb47Test
https://hdl.handle.net/10668/10417Test -
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المؤلفون: Luciano Cesar Pontes Azevedo, Flávia Ribeiro Machado, Reinaldo Salomão, J. E. Bezerra, J. Real
المصدر: Shock. 39:13-109
مصطلحات موضوعية: business.industry, Septic shock, Emergency Medicine, Cancer research, Medicine, Critical Care and Intensive Care Medicine, business, medicine.disease, Microvesicles, Preliminary analysis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::bad0db41dc8e34ce100357080c639f6bTest
https://doi.org/10.1097/shk.0b013e3182941440Test -
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المؤلفون: Pedro J. Real, Mireia Castillo, Weiyun Z. Ai, Carlos Cordon-Cardo, Irene Homminga, Teresa Palomero, Adolfo A. Ferrando, Jules P.P. Meijerink, Valeria Tosello, Elisa de Stanchina, Giuseppe Basso, Eva Hernando, Catherine M. Sawai, Kelly Barnes, Iannis Aifantis, Maria Luisa Sulis
المساهمون: Pediatrics
المصدر: Nature Medicine, 15(1), 50-58. Nature Publishing Group
Nature medicineمصطلحات موضوعية: Mice, SCID, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dexamethasone, Mice, 0302 clinical medicine, Glucocorticoid receptor, Antineoplastic Combined Chemotherapy Protocols, Cyclin D2, Homeostasis, Enzyme Inhibitors, Receptor, Notch1, Mice, Knockout, 0303 health sciences, Bcl-2-Like Protein 11, Gene Expression Regulation, Leukemic, General Medicine, Cell cycle, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, Signal Transduction, medicine.drug, endocrine system, T cell, Notch signaling pathway, Biology, Models, Biological, digestive system, Article, General Biochemistry, Genetics and Molecular Biology, Kruppel-Like Factor 4, 03 medical and health sciences, Receptors, Glucocorticoid, Downregulation and upregulation, Cyclins, Proto-Oncogene Proteins, medicine, Animals, Humans, Glucocorticoids, 030304 developmental biology, Membrane Proteins, Mice, Inbred C57BL, Drug Resistance, Neoplasm, Cancer research, biology.protein, Amyloid Precursor Protein Secretases, Apoptosis Regulatory Proteins, Amyloid precursor protein secretase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0fca13cb7acc7eca5b58255e5c4633Test
https://doi.org/10.1038/nm.1900Test -
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المؤلفون: Archana M. Agarwal, Esther Caparrós, Satoru Nagase, Juan Carlos Zúñiga-Pflücker, Adolfo A. Ferrando, Sherrie L. Perkins, Carlos Cordon-Cardo, Teresa Palomero, Pedro J. Real, Maria Dominguez, Mireia Castillo, Govind Bhagat, Kristy A. Brown, Maria Cortina, Ramon Parsons, Maria Ciofani, Jean Buteau, Maria Luisa Sulis, Kelly Barnes, Giuseppe Basso
المساهمون: Istituto di Ricerca Pediatrica Città della Speranza, Ministerio de Educación y Ciencia (España), Asociación Española Contra el Cáncer, National Institutes of Health (US), Charlotte Geyer Foundation, Golfers Against Cancer, Leukemia & Lymphoma Society (US)
المصدر: Nature Medicine. 13:1203-1210
مصطلحات موضوعية: Leukemia, T-Cell, DNA Mutational Analysis, T-cell leukemia, Notch signaling pathway, medicine.disease_cause, Article, General Biochemistry, Genetics and Molecular Biology, Mice, Phosphatidylinositol 3-Kinases, Pregnancy, hemic and lymphatic diseases, Transcriptional regulation, medicine, Animals, Drosophila Proteins, Humans, Tensin, PTEN, Transgenes, Phosphorylation, Receptor, Notch1, PI3K/AKT/mTOR pathway, Genetics, Models, Genetic, biology, Gene Expression Regulation, Leukemic, PTEN Phosphohydrolase, General Medicine, Disease Models, Animal, Mutation, embryonic structures, cardiovascular system, Cancer research, biology.protein, Drosophila, Female, sense organs, biological phenomena, cell phenomena, and immunity, Signal transduction, Carcinogenesis, Proto-Oncogene Proteins c-akt, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde30cef545685e1a42ed5c3320863d5Test
https://doi.org/10.1038/nm1636Test -
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المؤلفون: Jose L. Fernandez-Luna, Miguel Lafarga, Pedro J. Real, Adalberto Benito, Ana de Juan, Jorge Cuevas, Jose M. Lopez-Vega, Maria T. Berciano, Paul J. Coffer, Javier Gómez-Román
المساهمون: University of Groningen
المصدر: Cancer Research, 65(18), 8151-8157. AMER ASSOC CANCER RESEARCH
مصطلحات موضوعية: Cancer Research, Receptor, ErbB-2, Cetuximab, LINES, Apoptosis, ACTIVATION, Trastuzumab, Epidermal growth factor, Epidermal growth factor receptor, RNA, Small Interfering, skin and connective tissue diseases, biology, Forkhead Box Protein O3, DEATH, Antibodies, Monoclonal, Drug Synergism, Forkhead Transcription Factors, CHEMOTHERAPY, Immunohistochemistry, FAMILY, Up-Regulation, ErbB Receptors, Oncology, SURVIVAL, Female, Signal transduction, medicine.drug, Adult, Transcriptional Activation, Antineoplastic Agents, Breast Neoplasms, Antibodies, Monoclonal, Humanized, Transfection, Cell Line, LUNG-CANCER, Breast cancer, Growth factor receptor, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Humans, Chemosensitizing agent, Gene Silencing, business.industry, Tumor Suppressor Proteins, Membrane Proteins, medicine.disease, Immunology, Cancer research, biology.protein, business, RESISTANCE
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc1e4f55788fff2ffccefe7f4a2489bTest
https://doi.org/10.1158/0008-5472.can-05-1134Test -
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المؤلفون: Verónica Ramos-Mejía, Rosa Montes, Pedro J. Real, Oscar Navarro-Montero, Pablo Menendez, Damia Romero-Moya, Clara Bueno
المصدر: Clinical Immunology. 145:89-91
مصطلحات موضوعية: Lineage (genetic), Cd34 cells, Transplantation, Heterologous, Immunology, Antigen-Presenting Cells, Antigens, CD34, Mice, SCID, Nod, Biology, Mice, Mice, Inbred NOD, Animals, Humans, Immunology and Allergy, Cell Lineage, Graft Survival, Fetal Blood, Multi organ, Transplantation, Haematopoiesis, Animals, Newborn, Liver, Gamma Rays, Cord blood, Cancer research, Transplantation Tolerance, Cord Blood Stem Cell Transplantation, Interleukin Receptor Common gamma Subunit
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https://doi.org/10.1016Test/j .clim.2012.08.001 -
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المؤلفون: Pedro J. Real, Pablo Menendez, Oscar Navarro-Montero, Ed Stanley, Verónica Ayllón, Andrew G. Elefanty, Verónica Ramos-Mejía
المصدر: Experimental Hematology. 44:S89
مصطلحات موضوعية: Homeobox protein NANOG, Cancer Research, Haematopoiesis, Genetics, Cell Biology, Hematology, Biology, Stem cell, Molecular Biology, Embryonic stem cell, Cell biology, Adult stem cell
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::38d6fa60b4ca469cec12748d5648dd93Test
https://doi.org/10.1016Test/j .exphem.2016.06.186