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المؤلفون: Liqin Wang, Haojie Jin, Fleur Jochems, Siying Wang, Cor Lieftink, Isabel Mora Martinez, Giulia De Conti, Finn Edwards, Rodrigo Leite de Oliveira, Arnout Schepers, Yangyang Zhou, Jiaojiao Zheng, Wei Wu, Xingling Zheng, Shengxian Yuan, Jing Ling, Kathy Jastrzebski, Matheus Dos Santos Dias, Ji-Ying Song, Patrick N. H. Celie, Hideo Yagita, Ming Yao, Weiping Zhou, Roderick L. Beijersbergen, Wenxin Qin, René Bernards
المساهمون: Human genetics
المصدر: Nature Cancer, 3(11), 1284-1299. Nature Research
Wang, L, Jin, H, Jochems, F, Wang, S, Lieftink, C, Martinez, I M, de Conti, G, Edwards, F, de Oliveira, R L, Schepers, A, Zhou, Y, Zheng, J, Wu, W, Zheng, X, Yuan, S, Ling, J, Jastrzebski, K, Santos Dias, M D, Song, J-Y, Celie, P N H, Yagita, H, Yao, M, Zhou, W, Beijersbergen, R L, Qin, W & Bernards, R 2022, ' cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis ', Nature Cancer, vol. 3, no. 11, pp. 1284-1299 . https://doi.org/10.1038/s43018-022-00462-2Testمصطلحات موضوعية: Cancer Research, Oncology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a515cd48bd69c79c04ef44ba3703733Test
https://research.vumc.nl/en/publications/5cb78c17-95c0-4a56-91e6-59542f1c1a54Test -
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المؤلفون: René Bernards, Giulia De Conti, Lenno Krenning, Ziva Pogacar, Marieke van de Ven, Cor Lieftink, Arnout Schepers, Jackie Johnson, Arno Velds, Olaf van Tellingen, Kelvin Groot, Roderick L. Beijersbergen, Rodrigo Leite de Oliveira, Ji-Ying Song, Fleur Jochems, René H. Medema, Leyma Wardak, Liqin Wang
المساهمون: Human genetics
المصدر: PLoS ONE, 17(9 September):e0273182. Public Library of Science
Pogacar, Z, Johnson, J L, Krenning, L, de Conti, G, Jochems, F, Lieftink, C, Velds, A, Wardak, L, Groot, K, Schepers, A, Wang, L, Song, J-Y, van de Ven, M, van Tellingen, O, Medema, R H, Beijersbergen, R L, Bernards, R & Leite de Oliveira, R 2022, ' Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity ', PLoS ONE, vol. 17, no. 9 September, e0273182, pp. e0273182 . https://doi.org/10.1371/journal.pone.0273182Testمصطلحات موضوعية: Senescence, Sulfonamides, Multidisciplinary, biology, Chemistry, Pyridines, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Palbociclib, Piperazines, Downregulation and upregulation, Cell culture, Cell Line, Tumor, Cancer cell, Cancer research, biology.protein, Humans, biological phenomena, cell phenomena, and immunity, Kinase activity, Senolytic, Protein Kinase Inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a29ef97e9ee3d0ca0f36662417d453aTest
http://www.scopus.com/inward/record.url?scp=85137745306&partnerID=8YFLogxKTest -
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المؤلفون: Rodrigo Leite de Oliveira, Giulia De Conti, Cor Lieftink, Arnout Schepers, Roderick L. Beijersbergen, René Bernards, Ziva Pogacar, Fleur Jochems, Liqin Wang
المصدر: Mol Cancer Res
مصطلحات موضوعية: Senescence, Cancer Research, Autophagy-Related Proteins, Apoptosis, Biology, Article, Cell Line, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Autophagy, medicine, Autophagy-Related Protein-1 Homolog, Humans, CRISPR, Senolytic, Molecular Biology, Cellular Senescence, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Cancer, ULK1, medicine.disease, HEK293 Cells, Oncology, A549 Cells, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, CRISPR-Cas Systems
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab7c3c161e6fd4bc1fdc9b4e06ac955Test
https://doi.org/10.1158/1541-7786.mcr-21-0146Test -
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المؤلفون: Matheus H. Dias, Giulia De Conti, René Bernards
المصدر: Cancers, Vol 13, Iss 1118, p 1118 (2021)
Cancersمصطلحات موضوعية: 0301 basic medicine, Drug, Cancer Research, Multidrug tolerance, media_common.quotation_subject, cellular plasticity, Review, Drug resistance, Biology, lcsh:RC254-282, Fight-or-flight response, 03 medical and health sciences, 0302 clinical medicine, Drug tolerance, drug tolerance, medicine, adaptive resistance, media_common, Cancer, stress response, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, collateral vulnerability, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Adaptation, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4f18ef44b0b8c991b838c6d39603efTest
https://www.mdpi.com/2072-6694/13/5/1118Test -
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المؤلفون: Ziva Pogacar, Fleur Jochems, Cun Wang, Rodrigo Leite de Oliveira, Arnout Schepers, Haojie Jin, Lodewyk F. A. Wessels, Robin Janssen, Giulia De Conti, Roderick L. Beijersbergen, René Bernards, Bram Thijssen, Liqin Wang
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: Senescence, Transcriptome, Cell culture, Cancer cell, Cancer research, medicine, Cancer, Biology, Primary cell, Senolytic, medicine.disease, Phenotype
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e94afaf961ba0b5115fb2cfa7744e970Test
https://doi.org/10.2139/ssrn.3762763Test -
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المؤلفون: Andrea Umberto Cammarata, Debora Valli, Matteo Righi, Giulia De Conti, Alicja M. Gruszka, Massimiliano Mazza, Pier Giuseppe Pelicci
المصدر: Cancers, Vol 12, Iss 3768, p 3768 (2020)
Cancers
Volume 12
Issue 12مصطلحات موضوعية: 0301 basic medicine, Cancer Research, mouse model, Biology, lcsh:RC254-282, Article, Viral vector, Small hairpin RNA, 03 medical and health sciences, 0302 clinical medicine, PML-RAR, AML, medicine, Gene silencing, AML1-ETO, Gene knockdown, Hematopoietic stem cell, Myeloid leukemia, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, candidate genes
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebcb4aeffa2af0014dc9eded7898c8cTest
https://www.mdpi.com/2072-6694/12/12/3768Test -
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المصدر: Acute Promyelocytic Leukemia ISBN: 9783319642567
مصطلحات موضوعية: Leukemia, medicine.anatomical_structure, Cell of origin, Cell, Preleukemia, medicine, Cancer research, Leukemic Stem Cell, Biology, medicine.disease
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::df312bdeba1f713cef0a3aec54fb1b98Test
https://doi.org/10.1007/978-3-319-64257-4_3Test -
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المؤلفون: Pier Giuseppe Pelicci, Maria Mallardo, Maria Elena Boggio Merlo, Valentina Tabanelli, Emanuela Colombo, Angelica Calleri, Stefano Pileri, Giulia De Conti
المصدر: Experimental Hematology. 53:S123
مصطلحات موضوعية: Cancer Research, Leukemia, Haematopoiesis, Oncogene, Genetics, medicine, Cancer research, Cell Biology, Hematology, Biology, Stem cell, medicine.disease, Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::06ad19d9bf3cb6a505d892ccc4636192Test
https://doi.org/10.1016/j.exphem.2017.06.309Test -
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المؤلفون: Ciro Mercurio, Tiphanie Durfort, Marco Giorgio, Elena Ceccacci, Lucilla Luzi, Giulia De Conti, Luca Mazzarella, Anna Di Russo, Pier Giuseppe Pelicci, Paolo Falvo, Mohamed Elgendy, Anna Giulia Sanarico, Massimiliano Mazza, Paola Vianello, Rani Pallavi, Elena Mylonas, Massimo Stendardo, Pier Luigi Rossi, Luciano Giacò, Saverio Minucci
المصدر: Blood. 126:459-459
مصطلحات موضوعية: biology, Diet therapy, Immunology, Insulin inhibitor, Cell Biology, Hematology, Cell cycle, medicine.disease, Biochemistry, Transplantation, Insulin receptor, Leukemia, Downregulation and upregulation, biology.protein, medicine, Cancer research, NRF1
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::06fd986fd0eca65699034f94ef5dd5f1Test
https://doi.org/10.1182/blood.v126.23.459.459Test