المؤلفون: Jarom Heijmans, Wouter L. Smit

المساهمون: Graduate School, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, General Internal Medicine, Clinical Haematology

المصدر: Mol Cell Oncol
Molecular & cellular oncology, 8(4):1879614. Taylor and Francis Ltd.

مصطلحات موضوعية: Cancer Research, Messenger RNA, driver mutations, protein synthesis, Colorectal cancer, Translation (biology), Biology, medicine.disease_cause, medicine.disease, Cell biology, Transformation (genetics), Organoid, medicine, Protein biosynthesis, mTOR signaling, Author’s Views, Molecular Medicine, KRAS, Enhancer, neoplasms, global translation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8194db6dbc28c579cbb0459b38a72ff4Test
https://pubmed.ncbi.nlm.nih.gov/34616863Test

المؤلفون: Clare Fiala, Eleftherios P. Diamandis

المصدر: BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: 0301 basic medicine, Adult, DNA Mutational Analysis, Normal tissue, lcsh:Medicine, Context (language use), Disease, Review, medicine.disease_cause, Normal tissues, 03 medical and health sciences, Young Adult, 0302 clinical medicine, medicine, Humans, Gene, Aged, Mutation, Circulating tumor DNA, business.industry, lcsh:R, Driver mutations, Cancer, General Medicine, Middle Aged, medicine.disease, 030104 developmental biology, The Hallmarks of Cancer, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, business, Mutations, Passenger mutations

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e5e26cfddf582179c94bbbc1336f44Test
http://europepmc.org/articles/PMC7594459Test

المؤلفون: Irene Vanni, Enrica Teresa Tanda, Bruna Dalmasso, Lorenza Pastorino, Virginia Andreotti, William Bruno, Andrea Boutros, Francesco Spagnolo, Paola Ghiorzo

المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 7 (2020)

مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Mutation rate, driver mutations, medicine.medical_treatment, Disease, Review, Biology, medicine.disease_cause, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, medicine, melanoma, Molecular Biosciences, Gene, Molecular Biology, lcsh:QH301-705.5, non-BRAF mutation, Mutation, Genetic heterogeneity, Melanoma, medicine.disease, targeted therapy, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Cancer research, genetic, heterogeneity, WES, WGS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963d6500283ca19c51304fc876c8998cTest
http://europepmc.org/articles/PMC7396525Test

المؤلفون: Hans Clevers, Ivana Bozic, Chay Paterson

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Paterson, C, Clevers, H & Bozic, I 2020, ' Mathematical model of colorectal cancer initiation ', Proceedings of the National Academy of Sciences, vol. 117, no. 34, pp. 20681-20688 . https://doi.org/10.1073/pnas.2003771117Test
Proceedings of the National Academy of Sciences of the United States of America, 117(34), 20681-20688. National Academy of Sciences
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Mutation rate, Genes, APC, Carcinogenesis, Colorectal cancer, medicine.disease_cause, law.invention, Cancer evolution, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins p21(ras)/genetics, Genes, APC/physiology, Immune system, Theoretical, Mutation Rate, law, Models, Genotype, Medicine, Humans, p53/genetics, ras, Mutation, Multidisciplinary, Oncogene, business.industry, APC/physiology, Driver mutations, Cancer, Colonic Neoplasms/genetics, Oncogenes, Biological Sciences, Models, Theoretical, Genes, p53, medicine.disease, Colorectal Neoplasms/genetics, Genes, p53/genetics, Genes, ras, Stochastic model, Genes, Colonic Neoplasms, Cancer research, Disease Progression, Suppressor, Tumor Suppressor Protein p53/genetics, KRAS, Carcinogenesis/genetics, Tumor Suppressor Protein p53, Colorectal Neoplasms, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0be1b6f7a2a90b22b288ed47a748750Test

المؤلفون: Phyu P. Aung, Jonathan L. Curry, Dzifa Y. Duose, Sri Krishna C. Arudra, Leomar Y. Ballester, Doina Ivan, Haider A. Mejbel, Carlos A. Torres-Cabala, Victor G. Prieto, Dinesh Pradhan, Michael T. Tetzlaff, Raja Luthra, Priyadharsini Nagarajan

المصدر: Cancers, Vol 11, Iss 11, p 1714 (2019)
Cancers
Volume 11
Issue 11

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pathology, medicine.medical_specialty, driver mutations, Biology, medicine.disease_cause, lcsh:RC254-282, DNA sequencing, Article, 03 medical and health sciences, 0302 clinical medicine, tumor heterogeneity, medicine, melanoma, Neoplasm, Gene, Mutation, histophenotypic heterogeneity, Genetic heterogeneity, Melanoma, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 030104 developmental biology, Oncology, Tumor morphology, 030220 oncology & carcinogenesis, Immunohistochemistry, next-generation sequencing

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9656d65ef57d54663485da9aff6da058Test
https://www.mdpi.com/2072-6694/11/11/1714Test

المؤلفون: Helano C. Freitas, Giovana Tardin Torrezan, Isabela Werneck da Cunha, Mariana Petaccia Macedo, Vanessa Karen de Sá, Marcelo Corassa, Elisa Napolitano e Ferreira, Augusto Obuti Saito, Graziela Zibetti Dal Molin, Vladmir C. Cordeiro de Lima, Dirce Maria Carraro

المصدر: Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Neuroblastoma RAS viral oncogene homolog, Cancer Research, medicine.medical_specialty, Mutation rate, driver mutations, EGFR, medicine.disease_cause, lcsh:RC254-282, 03 medical and health sciences, symbols.namesake, Exon, 0302 clinical medicine, Internal medicine, medicine, Gene, Original Research, Sanger sequencing, molecular testing, business.industry, medicine.disease, Molecular diagnostics, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lung adenocarcinoma, targeted therapies, respiratory tract diseases, 030104 developmental biology, 030220 oncology & carcinogenesis, symbols, Adenocarcinoma, KRAS, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3599700fd86ea87693eb4838bea3dfb1Test
https://pubmed.ncbi.nlm.nih.gov/32714871Test

المؤلفون: Karl Hartmann, Bernd Klosterhalfen, Felipe Crespo, Nikolaos Mitsimponas, Maria Mitsogianni, Aristoteles Giagounidis, Sabine Haase

المصدر: Case Reports in Oncology
Case Reports in Oncology, Vol 11, Iss 1, Pp 109-113 (2018)

مصطلحات موضوعية: 0301 basic medicine, Lung adenocarcinoma, Case Report, medicine.disease_cause, lcsh:RC254-282, Hairy cell leukemia, 03 medical and health sciences, 0302 clinical medicine, Non-small cell lung cancer, medicine, BRAF-V600E mutation, Lung cancer, neoplasms, Mutation, Lung, business.industry, Driver mutations, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, digestive system diseases, BRAF V600E, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Concomitant, Cancer research, Adenocarcinoma, Non small cell, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4338c075b7febf42a5f0db89f807420fTest
http://europepmc.org/articles/PMC5869534Test

المؤلفون: Quincy Chu

المصدر: Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 12 (2020)

مصطلحات موضوعية: driver mutations, non-small cell lung cancer (NSCLC), Review, medicine.disease_cause, lcsh:RC254-282, EGFR exon 20, Epidermal growth factor, medicine, ROS1, Anaplastic lymphoma kinase, Epidermal growth factor receptor, Lung cancer, Protein kinase B, Mutation, biology, business.industry, MET exon 14, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, BRAF mutation, Oncology, HER-2, Cancer research, biology.protein, business, K-RAS, NRG, NTRK, MET amplification

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7f428687a05c5cf352b29c0af56e75Test
https://pubmed.ncbi.nlm.nih.gov/32047535Test

المؤلفون: Yijiu Ren, Shujun Huang, Chenyang Dai, Dong Xie, Larry Zheng, Huikang Xie, Hui Zheng, Yunlang She, Fangyu Zhou, Yue Wang, Pengpeng Li, Ke Fei, Gening Jiang, Yang Zhang, Bo Su, E. Alejandro Sweet-Cordero, Nhan Le Tran, Yanan Yang, Jai N. Patel, Christian Rolfo, Gaetano Rocco, Andrés Felipe Cardona, Alessandro Tuzi, Matteo B. Suter, Ping Yang, Wayne Xu, Chang Chen

المصدر: Frontiers in Oncology, Vol 9 (2019)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, driver mutations, Somatic cell, Oncology and Carcinogenesis, Biology, medicine.disease_cause, lcsh:RC254-282, Germline, 03 medical and health sciences, ground-glass nodule, 0302 clinical medicine, Germline mutation, medicine, Copy-number variation, whole-exome sequencing, Indel, Exome sequencing, Genetics, copy number variation, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lung cancer, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, KRAS, Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac04901cff495004843788e2346fac2Test

المؤلفون: Hendrik-Tobias Arkenau, Gonzalo Torga, Raluca Maria Fostea, Elisa Fontana

المصدر: Cancers, Vol 12, Iss 2599, p 2599 (2020)
Cancers

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, IDH1, driver mutations, molecular profiling, medicine.medical_treatment, Review, biliary tract cancers, medicine.disease_cause, lcsh:RC254-282, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Medicine, Chemotherapy, Heterogeneous group, business.industry, High mortality, Immunotherapy, targeted therapy, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, immunotherapy, cholangiocarcinoma, business, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb99fc1cbb8ef545c4adbbdd8334357Test
https://doi.org/10.3390/cancers12092599Test