يعرض 1 - 10 نتائج من 1,369 نتيجة بحث عن '"(1"', وقت الاستعلام: 1.01s تنقيح النتائج
  1. 1
    LINC00472 suppressed by ZEB1 regulates the miR‐23a‐3p/FOXO3/BID axis to inhibit the progression of pancreatic cancer

    المؤلفون: Gang Wang, Cong Bi

    المصدر: Journal of Cellular and Molecular Medicine

    مصطلحات موضوعية: Male, Carcinogenesis, pancreatic cancer, Mice, Nude, BH3 interacting-domain death agonist, Biology, medicine.disease_cause, Mice, microRNA‐23a‐3p, Nude mouse, In vivo, Pancreatic cancer, Cell Line, Tumor, medicine, Animals, Humans, Cell Proliferation, long intergenic non‐protein coding RNA 00472, Reporter gene, zinc finger E‐box binding homeobox 1, Zinc Finger E-box-Binding Homeobox 1, Cell Biology, Original Articles, Middle Aged, biology.organism_classification, medicine.disease, Gene Expression Regulation, Neoplastic, Pancreatic Neoplasms, MicroRNAs, Apoptosis, forkhead box O3, Cancer research, FOXO3, Molecular Medicine, Female, RNA, Long Noncoding, Original Article, BH3‐interacting domain death agonist

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b021f336e980680ff1bc6eae727c3b1Test
    http://europepmc.org/articles/PMC8419165Test


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  2. 2
    Integration of comprehensive genomic profiling, tumor mutational burden, and PD‐L1 expression to identify novel biomarkers of immunotherapy in non‐small cell lung cancer

    المؤلفون: Shiyue Zhang, Youming Lei, Juan Zhao, Songhui Zhao, Wen-Jing Wang, Ming Yao, Xiaowei Dong, Kai Wang, Li Liu, Qing Zhou, Yunfei Shi

    المصدر: Cancer Medicine
    Cancer Medicine, Vol 10, Iss 7, Pp 2216-2231 (2021)

    مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, medicine.medical_treatment, medicine.disease_cause, Immunotherapy, Adoptive, B7-H1 Antigen, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Medicine, tumor protein p53, Anaplastic Lymphoma Kinase, Copy-number variation, programmed cell death 1 ligand 1, Immune Checkpoint Inhibitors, Original Research, Gene Rearrangement, education.field_of_study, High-Throughput Nucleotide Sequencing, Genetic Profile, Middle Aged, Protein-Tyrosine Kinases, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lysine methyltransferase 2C, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, KRAS, non‐small cell lung cancer, Genetic Markers, China, Population, tumor mutation burden, lcsh:RC254-282, 03 medical and health sciences, Proto-Oncogene Proteins, ROS1, Biomarkers, Tumor, Humans, Radiology, Nuclear Medicine and imaging, education, Lung cancer, Aged, Retrospective Studies, business.industry, Proto-Oncogene Proteins c-ret, Cancer, Clinical Cancer Research, Immunotherapy, Genes, erbB-1, Histone-Lysine N-Methyltransferase, medicine.disease, Genes, p53, 030104 developmental biology, Genes, ras, Mutation, Cancer research, business

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07246db02928c9d4cd88d3dfd21b1b9dTest
    http://europepmc.org/articles/PMC7982619Test


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  3. 3
    Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

    المؤلفون: Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita

    المصدر: Cancer Immunology, Immunotherapy

    مصطلحات موضوعية: Male, Cancer Research, Pro-Opiomelanocortin, Paraneoplastic Syndromes, Programmed Cell Death 1 Receptor, Autoimmunity, Hypopituitarism, Immune checkpoint inhibitor, medicine.disease_cause, B7-H1 Antigen, Mice, 0302 clinical medicine, Neoplasms, Immunology and Allergy, CTLA-4 Antigen, Corticotrophs, Immune Checkpoint Inhibitors, Aged, 80 and over, biology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Paraneoplastic syndrome, Female, Original Article, Immunotherapy, Antibody, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, Hypophysitis, Immunology, 030209 endocrinology & metabolism, Adrenocorticotropic hormone, 03 medical and health sciences, Antigen, medicine, Animals, Humans, Aged, Retrospective Studies, business.industry, medicine.disease, biology.protein, Ectopic expression, Corticotropic cell, business, Adrenal Insufficiency

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc181a81511e7fe6b828ea748faa32Test
    https://hdl.handle.net/20.500.14094/90008773Test


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  4. 4
    NF1-mutated melanomas reveal distinct clinical characteristics depending on tumour origin and respond favourably to immune checkpoint inhibitors

    المؤلفون: Michael Weichenthal, Patrick Terheyden, Edgar Dippel, Georg Lodde, Rudolf A. Herbst, Inga Möller, Lisa Zimmer, Dirk Schadendorf, Julia Kretz, Peter Mohr, Ralf Gutzmer, Jochen Utikal, Eleftheria Chorti, Johanna Matull, Claudia Pföhler, Annette Paschen, Luisa Richter, Anne Zaremba, Philipp Jansen, Friedegund Meier, Selma Ugurel, Carl M. Thielmann, Antje Sucker, Eva Hadaschik, Jens Ulrich, Klaus G. Griewank, Alexander Kreuter, Rajmohan Murali, Elisabeth Livingstone

    المصدر: Eur J Cancer

    مصطلحات موضوعية: Adult, Male, Neuroblastoma RAS viral oncogene homolog, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Skin Neoplasms, Adolescent, Immune checkpoint inhibitors, Medizin, Gene mutation, medicine.disease_cause, Article, Young Adult, Humans, Medicine, Immune Checkpoint Inhibitors, Melanoma, neoplasms, Gene, Aged, Aged, 80 and over, Mutation, Neurofibromin 1, business.industry, Middle Aged, medicine.disease, Immune checkpoint, nervous system diseases, Oncology, Cohort, Cancer research, Female, business

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55018505c8924b71ce959451efd5e004Test
    https://doi.org/10.1016/j.ejca.2021.09.035Test


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  5. 5
    Long non-coding RNA (lncRNA) HOXD-AS2 promotes glioblastoma cell proliferation, migration and invasion by regulating the miR-3681-5p/MALT1 signaling pathway

    المؤلفون: Xingming Zhong, Yong Cai

    المصدر: Bioengineered
    article-version (VoR) Version of Record
    Bioengineered, Vol 12, Iss 2, Pp 9113-9127 (2021)

    مصطلحات موضوعية: Male, Carcinogenesis, LncRNA HOXD‐AS2, Down-Regulation, Mice, Nude, Apoptosis, miR-3681-5p, Bioengineering, Biology, medicine.disease_cause, Applied Microbiology and Biotechnology, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, Glioma, medicine, Animals, Humans, Gene silencing, Neoplasm Invasiveness, Gene Silencing, Cell Proliferation, Gene knockdown, Base Sequence, Cell growth, MALT1, General Medicine, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, Long non-coding RNA, Up-Regulation, nervous system diseases, Gene Expression Regulation, Neoplastic, MicroRNAs, Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein, Tumor progression, Gene Knockdown Techniques, Cancer research, Female, RNA, Long Noncoding, Glioblastoma, TP248.13-248.65, Signal Transduction, Research Article, Research Paper, Biotechnology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be60aceaf5b145e698f647a362495101Test
    https://doi.org/10.1080/21655979.2021.1977104Test


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  6. 6
    Circular RNA CELF1 drives immunosuppression and anti-PD1 therapy resistance in non-small cell lung cancer via the miR-491-5p/EGFR axis

    المؤلفون: Haitao Ma, Wen Ge, Jianjun Xu, Hao Chi, Hua Tang, Wan Cai, Jing Wang

    المصدر: Aging (Albany NY)

    مصطلحات موضوعية: Male, Aging, Lung Neoplasms, EGFR, medicine.medical_treatment, Programmed Cell Death 1 Receptor, NSCLC, medicine.disease_cause, Malignant transformation, Mice, Downregulation and upregulation, Circular RNA, In vivo, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Animals, Humans, Medicine, circ_CELF1, Lung cancer, miR-491-5p, Immune Checkpoint Inhibitors, business.industry, RNA, Circular, Cell Biology, Immunotherapy, Middle Aged, medicine.disease, respiratory tract diseases, ErbB Receptors, MicroRNAs, A549 Cells, Drug Resistance, Neoplasm, Cancer cell, Cancer research, Female, business, Carcinogenesis, Research Paper, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe80d3ce7b1de01f9f273d6987bf21bTest
    https://doi.org/10.18632/aging.203576Test


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  7. 7
    Restoration of HBV-specific CD8+ T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy

    المؤلفون: Zhigang Tian, Xiaokun Shen, Rui Sun, Chuang Guo, Binqing Fu, Haiming Wei, Jiabin Li, Dongyao Wang, Ying Ye, Junfei Zhang, Yanyan Liu

    المصدر: Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
    Signal Transduction and Targeted Therapy

    مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, Cell biology, Hepatitis B virus, Cancer Research, Adolescent, QH301-705.5, Programmed Cell Death 1 Receptor, CD8-Positive T-Lymphocytes, medicine.disease_cause, T-Lymphocytes, Regulatory, Article, Young Adult, Hepatitis B, Chronic, Immune system, Interferon, Drug Resistance, Viral, Genetics, medicine, Humans, Cytotoxic T cell, Hepatitis B e Antigens, IL-2 receptor, Biology (General), Aged, business.industry, Interleukin-2 Receptor alpha Subunit, Interferon-alpha, Interferon-Stimulated Gene Factor 3, Middle Aged, Recombinant Proteins, Clinical trial, Gene Expression Regulation, HBeAg, Immunology, Infectious diseases, Interleukin-2, Medicine, Female, business, CD8, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e45fff313f3e77b83a96cc5ccad309Test
    https://doaj.org/article/21b417eb6d294715b19d0a664f3c43a8Test


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  8. 8
    Nickel chloride regulates ANGPTL4 via the HIF-1α-mediated TET1 expression in lung cells

    المؤلفون: Yu-Ting Kang, Sheau-Chung Tang, Chien-Te Li, Yen-Chein Lai, I-Lun Hsin, Jiunn-Liang Ko, Yu-Ping Hsiao

    المصدر: Toxicology Letters. 352:17-25

    مصطلحات موضوعية: Male, Lung Neoplasms, Bisulfite sequencing, Adenocarcinoma of Lung, Bronchi, Toxicology, medicine.disease_cause, Mixed Function Oxygenases, Nickel, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Angiopoietin-Like Protein 4, Humans, Epigenetics, Lung cancer, Lung, Aged, Oncogene, biology, Epithelial Cells, General Medicine, Methylation, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Gene Expression Regulation, biology.protein, Cancer research, Demethylase, Adenocarcinoma, Female, Carcinogenesis

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4feb2a4e48fc8843ce32ef76878e44Test
    https://doi.org/10.1016/j.toxlet.2021.09.007Test


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  9. 9
    DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma

    المؤلفون: Jun-Jie Chen, Bin Zhu, Ying Feng, Jun-Ling Yang, Hua Huang, Wan-Jiang Xue, Wen Yuan Chung, Yi-Lin Hu

    المصدر: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
    Journal of Experimental & Clinical Cancer Research : CR

    مصطلحات موضوعية: DNA (Cytosine-5-)-Methyltransferase 1, Male, Cancer Research, Carcinoma, Hepatocellular, Angiogenesis, Down-Regulation, Mice, Nude, Transfection, medicine.disease_cause, Mice, chemistry.chemical_compound, Downregulation and upregulation, medicine, Animals, Humans, Gene silencing, HCC, RC254-282, Tube formation, DNA methylation, Research, Liver Neoplasms, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, miR-378a-3p, Vascular endothelial growth factor, TRAF1, TNF receptor associated factor, Oncology, chemistry, Cancer research, Carcinogenesis, Chromatin immunoprecipitation, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3184dab7eaed07e927a91570a256c08bTest
    https://doaj.org/article/92450d8b1f70426281f53b95df652367Test


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  10. 10
    Gastrointestinal stromal tumors with BRAF gene fusions. A report of two cases showing low or absent KIT expression resulting in diagnostic pitfalls

    المؤلفون: Lei Zhang, Ziyu Xie, Dianne Torrence, Ping Chi, Cristina R. Antonescu

    المصدر: Genes Chromosomes Cancer

    مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, Cancer Research, Oncogene Proteins, Fusion, Gastrointestinal Stromal Tumors, Nerve Tissue Proteins, PDGFRA, medicine.disease_cause, Article, Fusion gene, Young Adult, GTP-Binding Proteins, Genetics, medicine, Humans, Receptor, trkC, Receptor, Fibroblast Growth Factor, Type 1, neoplasms, Anoctamin-1, In Situ Hybridization, Fluorescence, Mutation, GiST, biology, CD117, GTPase-Activating Proteins, Imatinib, Gene rearrangement, Middle Aged, digestive system diseases, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Proto-Oncogene Proteins c-kit, Ribonucleoproteins, Imatinib Mesylate, Cancer research, biology.protein, Female, Myxoid Leiomyosarcoma, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6025e5a77624d3c37c3deb8d5c5844a8Test
    https://doi.org/10.1002/gcc.22991Test


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